Family U56
Summary for family U56
| Family type peptidase | U56.001 - homomultimeric peptidase (Thermotoga maritima), MEROPS Accession MER0005216 (peptidase unit: 1-259) |
| Content of family | Family U56 contains endopeptidases. |
| History |
Identifier created: MEROPS 8.2 (4 August 2008)
Familu U56 contains the homomultimeric peptidase (U56.001) from the hyperthermophilic bacterium Thermotoga maritima, which is so named because it consists of many identical subunits and forms a complex with a size in excess of 780 kDa. Individual subunits are 31 kDa (Hicks et al., 1998.
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| Catalytic type | Peptidase of unknown catalytic type |
| Active site | Neither active site residues nor the catalytic type have been determined. |
| Activities and specificities | The homomultimeric peptidase is able to hydrolyse substrates of chymotrypsin (S01.001) (such as substrate Val-Lys-Met-NHMec), trypsin (S01.151) and casein. Optimal conditions for activity are 90°C and pH 7.1 (Hicks et al., 1998). |
| Molecular structure | The homomultimeric peptidase is visible under transmission electron microscopy showing a large globular assembly (Hicks et al., 1998). It is not known how many subunits exist in the homomultimer. The amino acid sequence shows no relationship to any other peptidase. |
| Clan | unassigned |
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Distribution of family
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Bacteria |
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Archaea |
details |
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Protozoa |
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Fungi |
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Plants |
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Animals |
details |
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Viruses |
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| Peptidases and Homologues |
MEROPS ID |
Structure |
| homomultimeric peptidase | U56.001 | Yes |
| Family U56 unassigned peptidases | unassigned | Yes |
