Alignment for family C51
1 2 3 4 5 6 7 8 9 10 11 12
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1 --------MATYQEYKSRSNGNAYDID-GSFG-----------AQ----------------------------------------CWDGYADYCKYLGLPYAN------------------C---TNTGYARDIWE----------QRHENGILNYFD---------EVETM-------------QA----------------------------------GDVAIFMVVAGV-TPY--------------------------------------------------SHVAIFDSD---A---GGGYGWFLGQNQGGA----NG--AY 1
2 --------MATYQEYKSRSNGNAYDID-GSLG-----------AQ----------------------------------------CWDGYADYCKYLGLPYAN------------------C---TNTGYAKDIWE----------QRHKNGILNYFD---------EVETM-------------QA----------------------------------GDVAIFMVVAGV-TPY--------------------------------------------------SHVAIFDSD---A---GSGYGWFLGQNQGGA----NG--AY 2
3 --------MVAYLDFKSRVLNNGYDHDGGAFG-----------WQ----------------------------------------CWDGFAELCEANGIPIIN------------------TDPINHTGYAMDLWE----------QRKTNGMLTYFD---------EVETM-------------EG----------------------------------GDVAVFKEVAGV-TPS--------------------------------------------------SHVAIFDSD---I---DGVYGWFLGQNQGSTITHPNGGSAF 3
4 --------------------------------------------Q----------------------------------------CYP------------LIL----QYIR-----ALGYPWRNRDPSGNAFDLYE----------HFPTNGLGEFFDQVPTSRLDGGTNL-------------PQV----------------------------------GDIVVYGPGGYV-SEH--------------------------------------------------GHAAVVTAVRGNG---PLFGYETADQNSGG----------- 4
5 MQAKLTKKEFIEWLKTSEGKQ--YNADGW-YG-----------FQ----------------------------------------CFD------------YAN----AGWQ-----VLF--GYNLKGVG-AKDIPS----ANNFDGLATV-----YQN---------TPDFL------------AQP----------------------------------GDMVVFG--SNYGAGY--------------------------------------------------GHVAWVI----ET---TLDYIIVYEQNWLGGGWTDGVQQP- 5
6 MQAKLTKKEFIEWLKTSEGKQ--YNADGW-YG-----------FQ----------------------------------------CFD------------YAN----AGWK-----ALF--GLLLKGVG-AKDIPF----ANNFDGLATV-----YQN---------TPDFL------------AQP----------------------------------GDMVVFG--SNYGAGY--------------------------------------------------GHVAWVI----EA---TLDYIIVYEQNWLGGGWTDGVQQPG 6
7 ------KKEFIEWLKTSEGKQ--FNVDLW-YG-----------FQ----------------------------------------CFD------------YAN----AGWK-----VLF--GLLLKGLG-AKDIPF----ANNFDGLATV-----YQN---------TPDFL------------AQP----------------------------------GDMVVFG--SNYGAGY--------------------------------------------------GHVAWVI----EA---TLDYIIVYEQNWLGGGWTDGIEQPG 7
8 MQAKLTKKEFIEWLKTSEGKQ--FNVDLW-YG-----------FQ----------------------------------------CFD------------YAN----AGWK-----VLF--GLLLKGLG-AKDIPF----ANNFDGLATV-----YQN---------TPDFL------------AQP----------------------------------GDMVVFG--SNYGAGY--------------------------------------------------GHVAWVI----EA---TLDYIIVYEQNWLGGGWTDGIEQPG 8
9 MQAKLTKKEFIEWLKTSEGKQ--FNVDLW-YG-----------FQ----------------------------------------CFD------------YAN----AGWK-----VLF--GLLLKGLG-AKDIPF----ANNFDGLATV-----YQN---------TPDFL------------AQP----------------------------------GDMVVFG--SNYGAGY--------------------------------------------------GHVAWVI----EA---TLDYIIVYEQNWLGGGWTDGIEQPG 9
10 MQAKLTKNEFIEWLKTSEGKQ--FNVDLW-YG-----------FQ----------------------------------------CFD------------YAN----AGWK-----VLF--GLLLKGLG-AKDIPF----ANNFDGLATV-----YQN---------TPDFL------------AQP----------------------------------GDMVVFG--SNYGAGY--------------------------------------------------GHVAWVI----EA---TLDYIIVYEQNWLGGGWTDGIEQPG 10
11 MQAKLTKKEFIEWLKTSEGKQ--FNVDLW-YG-----------FQ----------------------------------------CFD------------YAN----AGWK-----VLF--GLLLKGLG-AKDIPF----ANNFDGLATV-----YQN---------TPDFL------------AQP----------------------------------GDMVVFG--SNYGAGY--------------------------------------------------GHVAWVI----EA---TLDYIIVYEQNWLGGGWTDRIEQPG 11
12 MQAKLTKKEFIEWLKTSEGKQ--FNADLW-YG-----------FQ----------------------------------------CFD------------YAN----AGWK-----VLF--GLLLKGLG-AKDIPF----ANNFDGLATV-----YQN---------TPDFL------------AQP----------------------------------GDMVVFG--SNYGAGY--------------------------------------------------GHVAWVI----EA---TLDYIIVYEQNWLGGGWTDGIEQP- 12
13 MQAKLTKKEFIEWLKTSEGKQ--FNVDLW-YG-----------FQ----------------------------------------CFD------------YAN----AAWK-----VLF--GLLLKGLG-AKDIPF----ANNFDGLATV-----YQN---------TPDFL------------AKP----------------------------------GDMVVFG--SNYGAGY--------------------------------------------------GHVAWVI----EA---TLDYIIVYEQNWLGGGWTDGIEQPG 13
14 MQAKLTKNEFIERLKTSEGKQ--FNVDLW-YG-----------FQ----------------------------------------CFD------------YAN----AGWK-----VLF--GLLLKGLG-AKDIPF----ANNFDGLATV-----YQN---------TPDFL------------AQP----------------------------------GDMVVFG--SNYGAGY--------------------------------------------------GHVAWVI----EA---TLDYIIVYEQNWLGGGWTDGIEQPA 14
15 MQAKLTKKEFIEWLKTSEGKQ--FNVDLW-YA-----------FQ----------------------------------------CFD------------YAN----AGWK-----ALF--GLLLKGVG-AKDIPF----ANNFDGLATV-----YQN---------TPDFL------------AQP----------------------------------GDMVVFG--SNYGAGY--------------------------------------------------GHVAWVI----EA---TLDYIIVYEQNWLGGGWTDGIEQP- 15
16 MQAKLTKKEFIEWLKTSEGKQ--FNIDLW-YA-----------FQ----------------------------------------CFD------------YAN----AGWK-----ALF--GLLLKGVG-AKDIPF----ANNFDGLATV-----YQN---------TPDFL------------AQP----------------------------------GDMVVFG--SNYGAGY--------------------------------------------------GHVAWVI----EA---TLDYIIVYEQNWLGGGWTDGIEQPG 16
17 MTATLTKEEFIKWLNNSVGKQ--YNEDLW-YG-----------FQ----------------------------------------CFD------------YAN----AGWK-----LLF--GHLLKGIG-AKDIPN----ANDFTNEATV-----YQN---------TPDFL------------AQP----------------------------------GDLVVFG--SNYGAGY--------------------------------------------------GHVAWVI----EA---TLDYIIVLEQNWLGGGWTDGIEQPG 17
18 MTAKLTKQEFINWLKQSEGKQ--YDMDGW-YG-----------FQ----------------------------------------CFD------------YAN----AGWQ-----QLF--GYNLSGAG-AKDIPF----VNNFTGKAKI-----IQN---------TPEFI------------AEA----------------------------------GDMVVFN--NKYGGGY--------------------------------------------------GHVAWVI----SA---DINNITVIEQNWLGGGWTNGPEQGG 18
19 -----TREEFVKWLKSTEGKQ--YDYDLY-AA-----------FQ----------------------------------------CFD------------YAN----VGWD-----KLF--GHGLKGNG-AKDIPFNAYNKDKFKNEATV-----YKN---------TPSFL------------AKP----------------------------------GDLVVWG--EQMGNGW--------------------------------------------------GHVAWVV----EA---TLDEITV------------------ 19
20 ----FTREEFVKWLKSTVGKQ--YDYDLY-AA-----------FQ----------------------------------------CVD------------YAN----VGWD-----KLF--GHGLKGNG-AKDIPFNDYNKDKFKNEATV-----YKN---------TPSFL------------AKP----------------------------------GDLVVWG--EQMGYGW--------------------------------------------------GHVAWVV----EA---TLDYIVVLEQNWLGGGWTSG----- 20
21 -----TKQEAIKWINNSIGKQ--YDFDGY-FG-----------FQ----------------------------------------CVD------------YSN----AYWN-----YVT--GGRLAGEG-AKDLPF----WNDFKGVATV-----YKN---------TPSFL------------AQG----------------------------------GDIVVWG--STFGNGF--------------------------------------------------GHTGVVI----DA---NSNYIVVVEQNWLLGGWTQGDARGG 21
22 MVSVRTYNQAIAYVKKMEGNA--YDPDRS-YG-----------AQ----------------------------------------CFD------------LAN----QYWL-----YLF--GHTLKGVG-AADIPT----WNNFTNEATV-----YEN---------TQTFQ------------AKP----------------------------------GDVVIFN--RNYGGGY--------------------------------------------------GHVAIVL----SA---TLNTINVIEQNWLGGAQWSPPEVAT 22
23 MASKRIYKDAIKYLKSMEGNA--YNPDRS-YG-----------FQ----------------------------------------CFD------------LAN----QWWL-----YLF--NHTLKGVG-AADIPT----WNNFKGEATV-----YEN---------TLSFQ------------AQP----------------------------------GDLVIFN--RNYGQGY--------------------------------------------------GHVAIVL----SA---TLNSITVLEQNWVGGAYWTPPEV-- 23
24 -----TYKQAISYLKSMEGHA--YNPDNA-FG-----------FQ----------------------------------------CVD------------AAN----QYWL-----YLF--NHTLKGVG-AADIPT----WNNFTNEATV-----YEN---------TQSFQ------------ALP----------------------------------GDVVIFN--RNYGDGY--------------------------------------------------GHVGIVI----SA---TLNSITILEQNWLGGAYWT------ 24
25 MTSIRTYKQAISYLKSMEGHA--YNPDNA-YG-----------VQ----------------------------------------CFD------------LAN----QYWL-----YLF--NHGLKGVG-AADIPT----WNNFTNEATV-----YEN---------TQSFQ------------ALP----------------------------------GDVVIFN--RNYGEGY--------------------------------------------------GHVGIVL----KA---TLNSITILEQNWLGGAYWTPPEVAT 25
26 MPSVRTYSQAISYLKSLEGKA--WNPDNA-FG-----------CQ----------------------------------------CFD------------TAN----QYWL-----YLF--NHRLKGVG-AADIPT----WNDFTNEATV-----YEN---------TVSFQ------------ALP----------------------------------GDVVIFN--RNYGGGY--------------------------------------------------GHVGIVI----SA---TLDSITILEQNWLGGAYWSPPEVTT 26
27 MPSVRTYSQAISYLKSLEGKA--WNPDNA-FG-----------CQ----------------------------------------CFD------------TAN----QYWL-----YLF--NHRLKGVG-AADIPT----WNDFTNEATV-----YEN---------TVSFQ------------ALP----------------------------------GDVVIFN--RNYGGGY--------------------------------------------------GHVGIVI----SA---TLDSITILEQNWLGGAY-------- 27
28 MPSVRTYSQAISYLKSLEGKA--WNPDNA-FG-----------CQ----------------------------------------CFD------------TAN----QYWL-----YLF--NHRLKGVG-AADIPT----WNDFTNEATV-----YEN---------TVSFQ------------ALP----------------------------------GDVVIFN--RNYGGGY--------------------------------------------------GHVGIVI----SA---TLDSITILEQNWLGGAYWSPPEVTT 28
29 MPSVRTYSQAISYLKSLEGKA--WNPDNA-FG-----------CQ----------------------------------------CFD------------TAN----QYWL-----YLF--NHRLKGVG-AADIPT----WNDFTNEATV-----YEN---------TVSFQ------------ALP----------------------------------GDVVIFN--RNYGGGY--------------------------------------------------GHVGIVI----SA---TLDSITILEQNWLGGAYWSPPEVTT 29
30 MPSVRTYSQAISYLKSLEGKA--WNPDNA-FG-----------CQ----------------------------------------CFD------------TAN----QYWL-----YLF--NHRLKGVG-AADIPT----WNDFTNEATV-----YEN---------TVSFQ------------ALP----------------------------------GDVVIFN--RNYGGGY--------------------------------------------------GHVGIVI----SA---TLDSITILEQNWLGGAYWSPPEVTT 30
31 MPSVRTYSQAISYLKSLEGKA--WNPDNA-FG-----------CQ----------------------------------------CFD------------TAN----QYWL-----YLF--NHRLKGVG-AADIPT----WNDFTNEATV-----YEN---------TVSFQ------------ALP----------------------------------GDVVIFN--RNYGGGY--------------------------------------------------GHVGIVI----SA---TLDSITILEQNWLGGAYWSPPEVTT 31
32 MPSVRTYSQAISYLKSLEGKA--WNPDNA-FG-----------YQ----------------------------------------CFD------------TAN----QYWL-----YLF--NHRLKGVG-AADIPT----WNDFTNEATV-----YEN---------TVSFQ------------ALP----------------------------------GDVVIFN--RNYGGGY--------------------------------------------------GHVGIVI----SA---TLDSITILEQNWLGGAYWSPPEVTT 32
33 MTSIRTYQQAISYLKSLEGKA--WNPDNA-YG-----------YQ----------------------------------------CFD------------TVN----QYWL-----YLF--GHMLKGIG-AADIPT----WNNFTNEATV-----YEN---------TLSFQ------------ALP----------------------------------GDVVIFN--RNYGQGY--------------------------------------------------GHTGIVL----SA---TLNSITILEQNWLGGAYWT------ 33
34 MVSVRTYKQSIAYLKSLEGKA--LNPDGA-YG-----------FQ----------------------------------------CFD------------VAN----QYWL-----YLF--GHTLKGVG-AADIPT----WNNFTGEATV-----YEN---------TLSFL------------AKP----------------------------------GDVVIFN--RNYGGGY--------------------------------------------------GHVGIVI----SA---TSNYITILEQNWVGGAYWT------ 34
35 MTSVRTYKQSIAYLKSLEGKA--LNPDGA-YG-----------FQ----------------------------------------CFD------------VAN----QYWL-----YLF--GHTLKGVG-AADIPT----WNNFTGEATV-----YEN---------TLSFL------------AKP----------------------------------GDVVIFN--RNYGGGY--------------------------------------------------GHVGIVI----SA---TSNYITILEQNWVGGAYWTPPKLLQ 35
36 -----TEKEAVKYIHSLEGKG--WDFDGS-WG-----------WQ----------------------------------------CFD------------EAN----MYWY-----ELF--GHGLKGEG-AADIPN----VNNFKGEATV-----YQN---------TVEFK------------AKA----------------------------------GDVVVFN--RNYGGGY--------------------------------------------------GHVAIVLDGNHDG---SYNQFLSLDQNWFGGG-LAKTEVAQ 36
37 -----TEKEAIDYIYNLEGKG--WDFDGV-YG-----------WQ----------------------------------------CVD------------LAN----MYWY-----KLF--GHGLKGEG-AADIPN----VNDFKGEATV-----YQN---------TPEFK------------AKP----------------------------------GDVVIFN--RNYGGGY--------------------------------------------------GHVAIVLDGNHDG---SYNSFVSLDQNWYGGG-LAKTEIAQ 37
38 -------NSKLKYLNSLVGKG--IDFDNA-YG-----------YQ----------------------------------------CVD------------VAN----HYWA-----HLF--NHGLKG-N-AIDIPS----ANNFKGEAKV-----YNN---------TPNFE------------AKP----------------------------------GDLVVFTNGQKYGSGF--------------------------------------------------GHVAVVTNGNVDG---NLQKFESLEQNWYGGG--------- 38
39 -------------LKTLENRG--WDFDGS-YG-----------WQ----------------------------------------CFD------------LVN----VYWN-----HIY--GHGLKGYG-AKDIPY----ANNFNSEAKI-----YHN---------TPTFK------------AEP----------------------------------GDLVVFS--GRFGGGY--------------------------------------------------GHTAIVLNGDYDG---KLMKFQSLDQNWNNGGW-------- 39
40 ----------LNYLKTLENRG--WDFDGS-YG-----------WQ----------------------------------------CFD------------LVN----VYWN-----HLY--GHGLKGYG-AKDIPY----ANNFNSEAKI-----YHN---------TPTFK------------AEP----------------------------------GDLVVFS--GRFGGGY--------------------------------------------------GHTAIVLNGDYDG---KLMKFQSLDQNWNNGGW-------- 40
41 NNKSNSNNSTLNYLKTLENRG--WDFDGS-YG-----------WQ----------------------------------------CFD------------LVN----VYWN-----HLY--GHGLKGYG-AKDIPY----ANNFNSEAKI-----YHN---------TPTFK------------AEP----------------------------------GDLVVFS--GRFGGGY--------------------------------------------------GHTAIVLNGDYDG---KLMKFQSLDQNWNNGGWRKAEVAHK 41
42 ----------LNYLKTLENRG--WDFDGS-YG-----------WQ----------------------------------------CFD------------LVN----VYWN-----HLY--GHGLKGYG-AKDIPY----ENNFNSEAKI-----YHN---------TPTFK------------AEP----------------------------------GDLVVFS--GRFGGGY--------------------------------------------------GHTAIVLNGDYDG---KLMKFQSLDQNWNNGGW-------- 42
43 -NRRNNSSSTLNYLNSLAYKG--WDFDGA-YG-----------NQ----------------------------------------CFD------------LVN----VYWN-----HLY--GHGLRGYG-AKDIPF----ANNFRGEATV-----YRN---------TPTFK------------AEL----------------------------------GDVTVFS--GRYGGGF--------------------------------------------------GHTAIVLNGNYDG---KLMKFQSLDQNWYGGDSRRADIAHK 43
44 ---------------TLQGRG--WDFDNF-AG-----------YQ----------------------------------------CFD------------LVN----VYWY-----HLY--GHGLNGMY-AKDIPF----QNDFTNEASV-----HQN---------TPSFK------------AYP----------------------------------GDVVVFG--NSYGKGM--------------------------------------------------GHVAIVTNGNVDG---NWNKFESLDQNWNHGG--------- 44
45 ---------------TLQGRG--WDFDNF-AG-----------YQ----------------------------------------CFD------------LAN----VYWY-----HLY--GHGLNGMY-AKDIPF----QNNFTNEASV-----HQN---------TPSFK------------AYP----------------------------------GDVVVFG--NSYGKGM--------------------------------------------------GHVAIVTNGNADG---NWNQFESLDQNWNHGG--------- 45
46 --TQYTQDEAIQHVESLNGQG--WDYDDA-YG-----------WQ----------------------------------------CFD------------LVN----EQWD-----YLY--GHGLKGDY-AKDIPE----ENNFIGEAQV-----YEN---------TEDFK------------ATA----------------------------------GDIVVFN--DAYGNGA--------------------------------------------------GHTAIVTNGNYDG---NYTQFQSLDQNWEGGG--------- 46
47 ----KTRSQAHAYLDRLKGYW--WDFDGV-YG-----------AQ----------------------------------------CFD------------LAN----QYWY-----YVT--GHTLSGMY-AKDIPF----VNDFNGYANV-----VKN---------YNSYI------------PKK----------------------------------GTLVVFPYEYG--NGC--------------------------------------------------GHVAIIES----A---TQNYFYSLDQNWYGGARNNPPE--- 47
48 ----KTRSQAHAYLDRLKGYW--WDFDGV-YG-----------AQ----------------------------------------CFD------------LAN----QYWY-----YVT--GHTLSGMY-AKDIPF----VNDFNGYANV-----VKN---------YNSYI------------PKK----------------------------------GTLVVFPYEYG--NGC--------------------------------------------------GHVAIIES----A---TQNYFYSLDQNWYGGARNNPPE--- 48
49 ----KTRSQAHAYLDRLKGYW--WDFDGV-YG-----------AQ----------------------------------------CFD------------LAN----QYWY-----YVT--GHTLSGMY-AKDIPF----VNDFNGYANV-----VKN---------YNSYI------------PKK----------------------------------GTLVVFPYEYG--NGC--------------------------------------------------GHVAIIES----A---TQNYFYSLDQNWYGGARNNPPEVAQ 49
50 ----KTRSQAHAYLDRLKGYW--WDFDGV-YG-----------AQ----------------------------------------CFD------------LAN----QYWY-----YVT--GHTLSGMY-AKDIPF----VNDFNGYANV-----VKN---------YNSYI------------PKK----------------------------------GTLVVFPYEYG--NGC--------------------------------------------------GHVAIIES----A---TQNYFYSLDQNWYGGARNNPPEVAQ 50
51 ----KTRSQAHAYLDRLKGYW--WDFDGV-YG-----------AQ----------------------------------------CFD------------LAN----QYWY-----YVT--GHTLSGMY-AKDIPF----VNDFNGYANV-----VKN---------YNSYI------------PKK----------------------------------GTLVVFPYEYG--NGC--------------------------------------------------GHVAIIES----A---TQNYFYSLDQNWYGGARNNPPEVAQ 51
52 ----KTRSQAHAYLDRLKGYW--WDFDGV-YG-----------AQ----------------------------------------CFD------------LAN----QYWY-----YVT--GRTLSGMY-AKDIPF----VNDFNGYANV-----VKN---------YNSYI------------PKK----------------------------------GTLVVFPYEYG--NGC--------------------------------------------------GHVAIIES----A---TQNYFYSLDQNWYGGARNNPPEVAQ 52
53 -----TRNQAHAYLDRLKGYW--WDFDGV-YG-----------AQ----------------------------------------CFD------------LAN----QYWY-----YVT--GHTLSGMY-AKDIPF----VNDFNGYANV-----VKN---------YNSYI------------PKK----------------------------------GTLVVFPYEYG--NGC--------------------------------------------------GHVAIIES----A---TQNYFYSLDQNWYGG---------- 53
54 ----KTRAQAHAYLRKLKGYW--WDFDGV-YG-----------AQ----------------------------------------CFD------------LAN----QYWY-----YVT--GHALRGLY-AKDIPF----ANNFDGYANV-----VKN---------YSSYV------------PKK----------------------------------GTLVIFPYEYG--NGS--------------------------------------------------GHVAIIES----A---TQNYFYSLDQNWYGGAQNNPPEVAQ 54
55 ----MTKSQAEKWLDNSEGKQ--YNFDNY-AG-----------FQ----------------------------------------CYD------------YAN----AFFN-----AVT--GARLTGLY-AKNIPF--DNEKVISKYAKV-----IKN---------YDSFL------------PRK----------------------------------TDIAVFN--GGYGGGA--------------------------------------------------GHVAPVT----RA---TLTQFEVLEQNWNGQGWTNGVASP- 55
56 ----MTRKQAENWLDNSEGRQ--YNADGY-YG-----------FQ----------------------------------------CYD------------YSK----MYFY-----VVT--GEWIGGLK-ASNIPF--DNKTKIEKYATI-----IKN---------YDSFL------------PQK----------------------------------GDIVCFP--DKYGGGY--------------------------------------------------GHTAVVT----RA---TLTQFEVLEQNWFGNGWTDGVVKP- 56
57 --MLITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----IAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 57
58 --MLITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----IAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 58
59 --MLITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----IAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 59
60 ----ITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----IAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQP- 60
61 --MLITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----IAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 61
62 --MLITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----IAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 62
63 --MLITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----IAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 63
64 --MLITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----IAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 64
65 --MLITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----IAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 65
66 --MLITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----IAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 66
67 --MLITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAS----MFFM-----IAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 67
68 ----ITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----IAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSYGQNWNGKGWTNGVAQP- 68
69 --MLITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----IAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSYGQNWNGKGWTNGVAQPG 69
70 --MLITKNQAEKWFDNSLGKQ--FNPDLF-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKAKIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 70
71 --MLMTKNQAEKWFDNSLGKQ--FNPDLF-FG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 71
72 --MLMTKNQAEKWFDNSLGKQ--FNPDLF-FG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKARIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 72
73 ----MTRNQAEKWFDNSLGKQ--FNPDGW-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKAKIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQP- 73
74 ----MTKNQAEKWFDNSLGKQ--FNPDGW-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKAKIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQP- 74
75 ----MTKNQAEKWFDNSLGKQ--FNPDGW-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKAKIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQP- 75
76 ----MTKNQAEKWFDNSLGKQ--FNPDGW-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKAKIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQP- 76
77 --MLMTKNQAEKWFDNSLGKQ--FNPDGW-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKAKIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 77
78 --MLMTKNQAEKWFDNSLGKQ--FNPDGW-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKAKIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 78
79 --MLMTKNQAEKWFDNSLGKQ--FNPDGW-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKAKIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 79
80 --MLMTKNQAEKWFDNSLGKQ--FNPDGW-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKAKIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 80
81 --MLMTKNQAEKWFDNSLGKQ--FNPDGW-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKAKIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 81
82 --MLMTKNQAEKWFDNSLGKQ--FNPDGW-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKAKIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 82
83 --MLMTKNQAEKWFDNSLGKQ--FNPDGW-YG-----------FQ----------------------------------------CYD------------YAN----MFFM-----LAT--GERLQGLY-AYNIPF--DNKAKIEKYGQI-----IKN---------YDSFL------------PQK----------------------------------LDIVVFP--SKYGGGA--------------------------------------------------GHVEIVE----SA---NLNTFTSFGQNWNGKGWTNGVAQPG 83
84 ---MKTYSEARARLRWYQGRY--IDFDGW-YG-----------YQ----------------------------------------CAD------------LAV----DYIY-----WLL--E--IRMWGNAKDAIN-----NDFKNMATV-----YEN---------TPSFV------------PQI----------------------------------GDVAVFT--KGIYKQY--------------------------------------------------GHIGLVFNG---G---NTNQFLILEQN-----YDGNANTPA 84
85 ---MKTYSEARARLRWYQGRY--IDFDGW-YG-----------YQ----------------------------------------CAD------------LAV----DYIY-----WLL--E--IRMWGNAKDAIN-----NDFKNMATV-----YEN---------TPSFV------------PQI----------------------------------GDVAVFT--KGIYKQY--------------------------------------------------GHIGLVFNG---G---NTNQFLILEQN-----YDGNANTPA 85
86 -------------LRWYQGRY--IDFDGW-YG-----------YQ----------------------------------------CAD------------LAV----DYIY-----WLL--E--IRMWGNAKDAIN-----NDFKNMATV-----YEN---------TPSFV------------PQI----------------------------------GDVAVFT--KGIYKQY--------------------------------------------------GHIGLVFNG---G---NTNQFLILEQN-----YDG------ 86
87 -----TYSEARARLRWYQGRY--IDFDGW-YG-----------YQ----------------------------------------CAD------------LAV----DYIY-----WLL--E--IRMWGNAKDAIN-----NDFKNMATV-----YEN---------TPSFV------------PQI----------------------------------GDVAVFT--KGIYKQY--------------------------------------------------GHIGLVFNG---G---NTNQFLILEQN-----YDG------ 87
88 ---MKTYSEARARLRWYQGRY--IDFDGW-YG-----------YQ----------------------------------------CAD------------LAV----DYIY-----WLL--E--IRMWGNAKDAIN-----NDFKNMATV-----YEN---------TPSFV------------PQI----------------------------------GDVAVFT--KGIYKQY--------------------------------------------------GHIGLVFNG---G---NTNQFLILEQN-----YDGNANTPA 88
89 ---MKTYSEARARLRWYQGRY--IDFDGW-YG-----------YQ----------------------------------------CAD------------LAV----DYIY-----WLL--E--IRMWGNAKDAIN-----NDFKNMATV-----YEN---------TPSFV------------PQI----------------------------------GDVAVFT--KGIYKQY--------------------------------------------------GHIGLVFNG---G---NTNQFLILEQN-----YDGNANTPA 89
90 ---MKTYSEARARLRWYQGRY--IDFDGW-YG-----------YQ----------------------------------------CAD------------LAV----DYIY-----WLL--E--IRMWGNAKDAIN-----NDFKNMATV-----YEN---------TPSFV------------PQI----------------------------------GDVAVFT--KGIYKQY--------------------------------------------------GHIGLVFNG---G---NTNQFLILEQN-----YDGNANTPA 90
91 ---MKTYSEARARLRWYQGRY--IDFDGW-YG-----------YQ----------------------------------------CAD------------LAV----DYIY-----WLL--E--IRMWGNAKDAIN-----NDFKNMATV-----YEN---------TPSFV------------PQI----------------------------------GDVAVFT--KGIYKQY--------------------------------------------------GHIGLVFNG---G---NTNQFLILEQN-----YDGNANTPA 91
92 ---MKTYSEARARLRWYQGRY--IDFDGW-YG-----------YQ----------------------------------------CAD------------LAV----DYIY-----WLL--E--IRMWGNAKDAIN-----NDFKNMATV-----YEN---------TPSFV------------PQI----------------------------------GDVAVFT--KGIYKQY--------------------------------------------------GHIGLVFNG---G---NTNQFLILEQN-----YDGNANTPA 92
93 ---MKTYSEARARLRWYQGRY--IDFDGW-YG-----------YQ----------------------------------------CAD------------LAV----DYIY-----WLL--E--IRMWGNAKDAIN-----NDFKNMATV-----YEN---------TPSFV------------PQI----------------------------------GDVAVFT--KGIYKQY--------------------------------------------------GHIGLVFNG---G---NTNQFLILEQN-----YDGNANTPA 93
94 ---MKTYSEARARLRWYQGRY--IDFDGW-YG-----------YQ----------------------------------------CAD------------LAV----DYIY-----WLL--E--IRMWGNAKDAIN-----NDFKNMATV-----YEN---------TPSFV------------PQI----------------------------------GDVAVFT--KGIYKQY--------------------------------------------------GHIGLVFNG---G---NTNQFLILEQN-----YDGNANTPA 94
95 ---MKTYSEARARLRWYQGRY--IDFDGW-YG-----------YQ----------------------------------------CAD------------LAV----DYIY-----WLL--G--IRMWGNAKDAIN-----NDFKNMATV-----YEN---------TPSFV------------PQI----------------------------------GDVAVFT--KGIYKQY--------------------------------------------------GHIGLVFNG---G---NTNQFLILEQN-----YDGNANTPA 95
96 ---MKTYSEARSRLRWYVGRY--IDFDGY-WA-----------YQ----------------------------------------CMD------------LAV----DYIY-----WLL--D--IRMWGNAKDAIN-----NDFKNMATI-----YEN---------TPSFV------------PQV----------------------------------GDVAVFR--NGIYKQY--------------------------------------------------GHIGIVYNS---G---NTNQFLILEQN-----FDGNANTPA 96
97 ---MKSQQQAKEWIYNHEGAG--VDFDGA-YG-----------FQ----------------------------------------CMD------------LAV----AYVY-----YIT--DGKVRMWGNAKDAIN-----NDFKGLATV-----YKN---------TPSFK------------PQL----------------------------------GDVAVYT--N---SQY--------------------------------------------------GHIQCVI-S---G---NLDYYTCLEQNWLNGGFDK------ 97
98 ---MKSQQQAKEWIYKHEGAG--VDFDGA-YG-----------FQ----------------------------------------CMD------------LSV----AYVY-----YIT--DGKVRMWGNAKDAIN-----NDFKGLATV-----YKN---------TPSFK------------PQL----------------------------------GDVAVYT--N---GQY--------------------------------------------------GHIQCVL-S---G---NLDYYTCLEQNWLGGGFDG------ 98
99 ---MKSQQQAKEWIYKHEGAG--VDFDGA-YG-----------FQ----------------------------------------CMD------------LSV----AYVY-----YIT--DGKVRMWGNAKDAIN-----NDFKGLATV-----YKN---------TPSFK------------PQL----------------------------------GDVAVYT--N---GQY--------------------------------------------------GHIQCVL-S---G---NLDYYTCLEQNWLGGGFDG------ 99
100 ---MKSQQQAKDWIYKHEGVG--VDFDGA-YG-----------FQ----------------------------------------CMD------------LAV----AYIY-----YIT--DGKVRMWGNAKDAIN-----NDFKGLATV-----YEN---------TSSFK------------PQL----------------------------------GDVAVYT--N---SQY--------------------------------------------------GHIQCVT-S---G---NLDYYTCLEQNWLNGGYDG------ 100
101 ---MKSQQQAKEWIYKHEGVG--VDFDLA-FG-----------YQ----------------------------------------CAD------------LAV----AYIY-----YIT--DGKVRMWGNAKDAIN-----NDFKGLATV-----YEN---------TPNFK------------PQL----------------------------------GDVAVYT--NGQYGQY--------------------------------------------------GHIQCVL-S---G---NLDYYTCLEQNWLGGGFDG------ 101
102 -----TKAQAKSWINSKVGKG--IDWDGM-YG-----------YQ----------------------------------------CMD------------EAV----DYIH-----YVT--DGKVTMWGNAIDAPK-----NNFQGLCTV-----YTN---------TPEFR------------PAY----------------------------------GDVIVWS--YGTFATY--------------------------------------------------GHIAIVVNPDPYG---DLQYITALEQNWNGNG--------- 102
103 ---MKTKAQAKSWINSKIGKG--IDWDGM-YG-----------YQ----------------------------------------CMD------------EAV----DYIH-----HVT--DGKVTMWGNAIDAPK-----NNFQGLCTV-----YTN---------TPEFR------------PAY----------------------------------GDVIVWS--YGTFATY--------------------------------------------------GHIAIVVNPDPYG---DLQYITVLEQNWNGNGIYK------ 103
104 ---MKTLKQAESYIKSKVNTG--TDFDGL-YG-----------YQ----------------------------------------CMD------------LAV----DYIY-----HVT--DGKIRMWGNAKDAIN-----NSFGGTATV-----YKN---------YPAFR------------PKY----------------------------------GDVVVWT--TGNFATY--------------------------------------------------GHIAIVTNPDPYG---DLQYVTVLEQNWNGNGIYK------ 104
105 ---VKTWTSYDPAFSTMEPGC--VDVDHF-YH-----------AQ----------------------------------------CAD------------LPT----DYIL-----WLT--DNQYKAWGNAKDFPN-----NKFPTGWKV-----IEN---------MPETV------------PQK----------------------------------GWIAVFT--SGTYAQY--------------------------------------------------GHIGIVYNG---G---NTNSFQILEQNWNG-----YANKKP 105
106 ---VKVWTSYDNRFYPMEPGC--IDVDKS-FH-----------AQ----------------------------------------CAD------------LTI----DYIL-----WLT--DNEFRIRGNAKDAINPK--KNKLPEGWKI-----VLN---------RPSTV------------PRK----------------------------------GWIAVFT--DGTYWEY--------------------------------------------------GHIGMVYDG---G---NTSRFQILEQNWNG-----WANKKP 106
107 ----------------MEPGC--IDVDRS-FH-----------AQ----------------------------------------CMD------------LVI----DYCL-----WIS--DNQFRIRGNAKQAID-----NPLPKGWKI-----IRN---------ERATV------------PKQ----------------------------------GWIGVNT--S-TY--Y--------------------------------------------------GHIWLVDKG---A---TQMTMPVIEQNWNS-----LANLKP 107
108 ------------------GQW--IDTDGY-YG-----------AQ----------------------------------------CKD------------FVNAFTQDNFG-----VTFP-GNACDLIY-D-SLPA----G--W----QR-----IQN---------YAEFV------------PEP----------------------------------GDIAIWGGWNG--NPY--------------------------------------------------GHTAIIVS----A---NLYTFDSVDQNWV------------ 108
109 -----TKEQGAQWALDRVGQS--IDVDGY-YG-----------AQ----------------------------------------CKD------------FVEKFTTENFG-----VSFP-GNAIDLIY-C-AIPS----G--W----QR-----IKN---------TPEFL------------PQP----------------------------------GDIALWA---Y--GTY--------------------------------------------------GHTGIIVS----A---NLNTFVSVDQNWYNASSNGSPAAK- 109
110 -----SREDAVKWAYAQEGKF--LDYDKV-YG-----------AQ----------------------------------------CVD------------LVHYYYAYFGK-----ASYATGNGCDFVN-N-KLPD----G--W----TR-----IKN---------TADFV------------PQP----------------------------------GDIAVWG-KEL--SQY--------------------------------------------------GHVAIILS----A---DAHSFVSMDQNWPRG---------- 110
111 KTGKPTAKQVVDWAINLIGSG--VDVDGY-YG-----------RQ----------------------------------------CWD------------LPNYIFNRYWG-----FKTP-GNARDMAW-Y-RYPA----G--F----KI-----YKN---------TTNFV------------PKP----------------------------------GDMAIWTGGNYNWNTW--------------------------------------------------GHTGIVVGP---S---TKDYFYSVDQNWNNANSYVGSPAAK 111
112 KTGKPTAKQVVDWAINLIGSG--VDVDGY-YG-----------RQ----------------------------------------CWD------------LPNYIFNRYWN-----FKTP-GNARDMAW-Y-RYPE----G--F----KV-----FRN---------TSDFV------------PKP----------------------------------GDIAVWTGGNYNWNTW--------------------------------------------------GHTGIVVGP---S---TKSYFYSVDQNWNNSNSYVGSPAAK 112
113 ------------------------------YG-----------AQ----------------------------------------CWD------------LPNYLFYKIWG-----FKTP-GNARDIPF-YNNYPR----G--F----QI-----IRN---------TPEFI------------PEP----------------------------------GDIAVWTAESDPWIRW--------------------------------------------------GHTDIVIGP---S---TKDYFWGVDQNWF------------ 113
114 KTRKPTASEVVEWAKSNIGKR--INIDNY-RG-----------SQ----------------------------------------CWD------------TPNFIFKRYWG-----FVTW-GNAKDMAN-Y-RYPK----G--F----RF-----YRY---------SSGFV------------PEP----------------------------------GDIAVWHPGNGI-GSD--------------------------------------------------GHTAIVVGP---S---NKSYFYSVDQNWVNSNSWTGSPGRL 114
115 KTRKPTASEVVEWAKSNIGKR--INIDNY-RG-----------SQ----------------------------------------CWD------------TPNFIFKRYWG-----FVTW-GNAKDMAN-Y-RYPK----G--F----RF-----YRY---------SSGFV------------PEP----------------------------------GDIAVWHPGNGI-GSD--------------------------------------------------GHTAIVVGP---S---NKSYFYSVDQNWVNSNSWTGSPGRL 115
116 KTRKPTASEVVEWAKSNIGKR--INIDNY-RG-----------SQ----------------------------------------CWD------------TPNFIFKRYWG-----FVTW-GNAKDMAN-Y-RYPK----G--F----RF-----YRY---------SSGFV------------PEP----------------------------------GDIAIWHPGNGI-GSD--------------------------------------------------GHTAIVVGP---S---NKSYFYSVDQNWVNSNSWTGSPGRL 116
117 KTRKPTASEVVEWAKSNIGKR--INIDNY-RG-----------SQ----------------------------------------CWD------------TPNFIFKRYWG-----FVTW-GNAKDMAN-Y-RYPK----G--F----RF-----YRY---------SSGFV------------PEP----------------------------------GDIAVWHPGNGI-GSD--------------------------------------------------GHTAIVVGP---S---NKSYFYSVDQNWVNSYSWTGSPGRL 117
118 KTRKPTASEVVEWAKSNIGKR--INIDNY-RG-----------SQ----------------------------------------CWD------------TPNFIFKRYWG-----FVTW-GNAKDMAN-Y-RYPK----G--F----RF-----YRY---------SSGFV------------PEP----------------------------------GDIAVWHPGNGI-GSD--------------------------------------------------GHTAIVVGP---S---NKSYFYSVDQNWVNSNSWTGSPGSL 118
119 KTRKPTASEVVEWAKSNIGKR--INIDNY-RG-----------SQ----------------------------------------CWD------------TPNFIFKRYWG-----FVTW-GNAKDMAN-Y-RYPK----G--F----RF-----YRY---------SSGFV------------PEP----------------------------------GDIAVWHPGNGI-GSD--------------------------------------------------GHTAIVVGP---S---NKSYFYSVDQNWVNSNSWTGSPGSL 119
120 KTRKPTASEVVEWAKSNIGKR--INIDNY-RG-----------SQ----------------------------------------CWD------------TPNFIFKRYWG-----FVTW-GNAKDMAN-Y-RYPK----G--F----RF-----YRY---------SSGFV------------PEP----------------------------------GDIAVWHPGSGI-GSD--------------------------------------------------GHTAIVVGP---S---NKSYFYSVDQNWVNSNSWTGSPGSL 120
121 KTRKPTASEVAEWAKSNIGKR--INIDGY-RG-----------SQ----------------------------------------CWD------------TPNFIFKRYWG-----FVTW-GNAKDMAN-Y-RYPK----G--F----RF-----YRY---------TSGFV------------PEP----------------------------------GDMAVWHPGNGI-GSD--------------------------------------------------GHTAIVVGP---S---NKSYFYSVDQNWVNSNSWTGSPGAL 121
122 -KRKPTASEVVEWAKSMKGKR--VDVDGY-YG-----------AQ----------------------------------------CWD------------LPNYIFNRFWN-----FRTW-GNAVDMSR-Y-KYPK----G--F----RF-----HRY---------TSSFI------------PKP----------------------------------GDIAVWHPGNGI-GSA--------------------------------------------------GHTAIVVGP---S---DKSYFYSIDQNWVGANGWT------ 122
123 KKRKPTASEVAAWAKSRIGKR--LDVDGY-YG-----------AQ----------------------------------------CWD------------LPNYIFKRYWG-----FFTT-GNAIAMAW-Y-RYPR----G--F----KF-----YRN---------TRNFV------------PKP----------------------------------GDMAVWGKGSYN-NGT--------------------------------------------------GHTAVVVGP---S---NKSYFTSVDQNWRNSNGYTGSPGSL 123
124 KKRKPTASEVAAWARSRIGKR--LDIDGR-GG-----------AQ----------------------------------------CWD------------LPNYIFGRYWN-----FWCN-GNAIHMAW-Y-RYPR----G--F----KF-----YRN---------TASFV------------PEP----------------------------------GDMAVWGTGSFN-NGV--------------------------------------------------GHTAVVVGP---S---NRNYFTSVDQNWRNANGYTGSPGSL 124
125 --RKPTASEVAAWAKSNIGKR--VDVDGY-RG-----------AQ----------------------------------------CWD------------TPNFIFKRYWN-----FTTW-GNAMHMAF-Y-KYPR----G--F----KF-----YPN---------TANFV------------PKP----------------------------------GDMAVWGKGSFN-NGT--------------------------------------------------GHTAIVVGP---S---NKSYFYSVDQNWRNSNGWTGSPGSL 125
126 KRRKPTASEVAAWAKRMIGRR--VDVDGY-YG-----------AQ----------------------------------------CWD------------LPNYIFNRYWH-----FKTT-GNAIAMAW-Y-RYPK----G--F----KF-----YRN---------TRNFV------------PKP----------------------------------GDMAVWGKGSFN-NGV--------------------------------------------------GHTAVVIGP---S---TKSYFTSVDQNWIGANSYTGSPGA- 126
127 KRRKPTASEVAAWAKRMIGRR--VDVDGY-YG-----------AQ----------------------------------------CWD------------LPNYIFNRYWH-----FKTT-GNAIAMAW-Y-RYPK----G--F----KF-----YRN---------TRNFV------------PKP----------------------------------GDMAVWGKGSFN-NGV--------------------------------------------------GHTAVVIGP---S---TKSYFTSVDQNWIGANSYTGSPGA- 127
128 ---------------------KGVNIDGR-FG-----------FQ----------------------------------------CWD------------LPNYIFNRYWH-----FRTW-GNANAMAN-RSNYPN----S-SW----KI-----YRN---------TSSFV------------PQP----------------------------------GDIVCWTY-----GYA--------------------------------------------------GHTGIVVGP---S---DKKHFRTVDQNWFNSNQYVGSRAAY 128
129 KSGKPTAQNVVDWALDLARRRSGVNIDGY-YG-----------MQ----------------------------------------CWD------------LPNYILKRYWG-----FTTW-GNANAMAI-KSNY-R----GYDF----KI-----YRN---------TASFV------------PRP----------------------------------GDWAVWAG-----SNP--------------------------------------------------GHVAIVVGP---S---TTNYFYSVDQNWYTAN-WSGSPAYK 129
130 KNRKPTASEVVEWALYIAKNKIAIDVPGSGMG-----------AQ----------------------------------------CWD------------LPNYLLDKYWG-----FRTW-GNADAMAQ-KSNY-R----GRDF----KI-----IRN---------TKDFV------------PQP----------------------------------GDWGVWTG-----GWA--------------------------------------------------GHVNIVVGP---C---TKDYWYGVDQNWYTNNA-TGSPPYK 130
131 KNRKPTASEVVEWALYIAKNKIAIDVPGSGMG-----------AQ----------------------------------------CWD------------LPNYLLDKYWG-----FRTW-GNADAMAQ-KSNY-R----GRDF----KI-----IRN---------TKDFV------------PQP----------------------------------GDWGVWTG-----GWA--------------------------------------------------GHVNIVVGP---C---TKDYWYGVDQNWYTNNA-TGSPPYK 131
132 KNRKPTASEVVEWALYIAKNKIAIDVPGSGMG-----------AQ----------------------------------------CWD------------LPNYLLDKYWG-----FRTW-GNADAMAQ-KSNY-R----GRDF----KI-----IRN---------TKDFV------------PQP----------------------------------GDWGVWTG-----GWA--------------------------------------------------GHVNIVVGP---C---TKDYWYGVDQNWYTNNA-TGSPPYK 132
133 --------------------------------------------Q----------------------------------------CCD------------LPCFIVKNWFG-----IDL-WGNAIDLLNSASAQGL------------EV-----IYN---------APGVN------------PKA----------------------------------SDLFVMEVAGS---PY--------------------------------------------------GHTGAVIED---S---DGYTIKTVEQNIDGNW--------D 133
134 ---MATVSEVISYWRGLADTNQGYDADLA-WG-----------WQ----------------------------------------CAD------------VTNGTTTNFFG-----VTL-WGNAIDLLDSAKAQGL------------EV-----IYD---------APGIN------------PKA----------------------------------GDLFVMYTYAH---PY--------------------------------------------------GHTGIVIAD---S---DGYTIQTIEQNVDGYSDNNGDGIND 134
135 ---MATLDEVLSFAKGLADAGQGVDLDNV-YG-----------TQ----------------------------------------CVD------------LPNWITTKYFG-----IAL-WGNAIDLLDSAAAQGM------------EV-----VYN---------APGVN------------PRA----------------------------------GAIFVMVTYAH---GY--------------------------------------------------GHTGLVIVT---S---DGYVLHNIEQNVDGNA--------D 135
136 QMISSQCREVIEFFINLVNAGVGVDKDGF-AG-----------WQ----------------------------------------CTD------------VPCYAAKHWFG-----VDL-WGNAIDLLDSAAAVGW------------EV-----HRM---------PTDAN------------PQT----------------------------------GAFFVQSVPYH---QF--------------------------------------------------GHTGVVIED---S---DGYTMRTIEQNIDGNP--------D 136
137 KMISSQCREVIEFFINLANAGMGVDKDSF-AG-----------WQ----------------------------------------CAD------------VPCYAAKHWFD-----VDL-WGNAIDLLDSAAALGW------------EV-----HRM---------PTDAN------------PLT----------------------------------GAFFVQSVPYH---QF--------------------------------------------------GHTGIVIED---S---DGYTMRTVEQNIDGNP--------D 137
138 QMISSQCREVIEFYINLANAGMGVDKDGA-YG-----------TQ----------------------------------------CAD------------VPCYAAKHWFG-----VDL-WGNAADLLDSASAQGW------------EV-----HRM---------PTDAN------------PRA----------------------------------GAFFVMDAWFG-GINY--------------------------------------------------GHTGLVYVD---S---DGYTMQTIEQNIDGNA--------D 138
139 ---MTTANEIVQYCVNLANSGTGVDKDGA-HG-----------TQ----------------------------------------CCD------------LPCFVAKNWFG-----VDL-WGNAIDLLDSASAQGW------------EV-----HRM---------PTEAN------------PKA----------------------------------GATFVQSVPYH---QF--------------------------------------------------GHTGIVIED---S---DGYTMRTVEQNIDGNA--------D 139
140 EETMTTANEIVQYCVNLANSGMGVDKDGA-HG-----------TQ----------------------------------------CCD------------LPCFVAKNWFG-----VDL-WGNAIDLLDSASAQGW------------EV-----HRM---------PTEAN------------PKA----------------------------------GATFVQSVPYH---QF--------------------------------------------------GHTGIVIED---S---DGYTMRTVEQNIDGNA--------D 140
141 EETMTTANEIVQYCVNLANSGMGVDKDGA-HG-----------TQ----------------------------------------CCD------------LPCFVAKNWFG-----VDL-WGNAIDLLDSASAQGW------------EV-----HRM---------PTEAN------------PKA----------------------------------GATFVQSVPYH---QF--------------------------------------------------GHTGIVIED---S---DGYTMRTVEQNIDGNA--------D 141
142 -----TVNEVVNFAKDLANRGQGVDYDGW-YG-----------NQ----------------------------------------CVD------------LPNWICGKFFG-----KPL-WGNAIDLIKSAKQHGF------------EV-----HYM---------PTSER------------PRP----------------------------------GAIFVKNYWASDGVNY--------------------------------------------------GHTGLIIGV---S----GNAVQTIEQNLVG----------- 142
143 ------------------------------YG-----------GQ----------------------------------------CVA------------LIDKIVQEETG-----KNMSYTNAIDCLDKAKANGF------------QV-----TYD---------AVGVN------------PQA----------------------------------GDFYVIRVPSH---SF--------------------------------------------------GHIGVCLAD---S---DGTGLEGVEQNVDGYSDSNRNGVND 143
144 -------------------------------G---------MKWQ----------------------------------------CVE------------FAR----RYWM----LRGKPTPAFFGPVVGAADIWDTLTHVTFLDNATTA-PLLKFKN---------GARLG-------YGGSAPRV----------------------------------GDLLIYPRDAEGFFSY--------------------------------------------------GHVAVVVR----V---------------------------- 144
145 -------------------------------G---------MKWQ----------------------------------------CVE------------FAR----RYWM----LRGKPTPAFFGPVVGAADIWDTLTHVTFLDNATTA-PLLKFKN---------GARLG-------YGGSAPRV----------------------------------GDLLIYPRDAEGFFSY--------------------------------------------------GHVAVVVR----V---------------------------- 145
146 -------------------------------G---------MKWQ----------------------------------------CVE------------YAR----RYWM----LRGTPTPAFFGAVKGAADIWDSLTHVTFLDNATTA-PLLKFKN---------GARLG-------YGGSAPRV----------------------------------GDLLIYPRDTENVFPY--------------------------------------------------GHVAVVVK----V---------------------------- 146
147 -------------ENTTTYNNVTVAGTSYQSG---------LKWQ----------------------------------------CVE------------YAR----RYWM----LRGTPQPATFGSVDGAADIWD-LKDIQLLNGQKRK-PLLKYHN---------GNATS--------ANSKPRV----------------------------------GDLLIYPRQPNG-FPC--------------------------------------------------GHVAVVVG----V---TGDRMFVAEQNWENAAW-PGPYHNY 147
148 VSTELGYINLTVLELNNETGQVTYISKQFYTG---------LAWQ----------------------------------------CVE------------YAR----RYWM----QSGTPQPAYFESVPGAADIWN-LTFVRLLSNTSMKLPLHRFRN---------GDPVT-------SNLQVPAV----------------------------------GDIIIYPVQDGG-FPY--------------------------------------------------GHVAVIAS----VEISTHGAIYVAEQNWANAVW-PSAYHNY 148
149 VSTELGYINLTVPELNNETGQVTYISKQFYTG---------LAWQ----------------------------------------CVE------------YAR----RYWM----QSGTPQPAYFESVPGAADIWN-LTFVRLLSNTSMKLPLHRFRN---------GDPVT-------SNLQVPAV----------------------------------GDIIIYPVQDGG-FPY--------------------------------------------------GHVAVIAS----VEISTHGAIYVAEQNWANAVW-P------ 149
150 VSTELRYINLTVPELNNETGQLTYISKQFYTG---------LAWQ----------------------------------------CVE------------YAR----RYWM----QRGTPQPAYFDSVLGAADVWN-LTFVRLLSNASITLPLRRYWN---------GDRVT-------DNHQIPAI----------------------------------GDIIIYPVQDGG-FPY--------------------------------------------------GHVAVIAN----VELSTHGAIYVAEQN-------------- 150
151 ------------------------------LG---------VKWQ----------------------------------------CVE------------FAR----RYLA----SR---KAVWTASMPIAADMWRAET------------PFVRVQD---------GTPVEFTRIANRSHGPAPAM----------------------------------SDIIVWGQSEET--PF--------------------------------------------------GHVAVVTE----V---LPEAVRVAEQNQGFERW-PQGMLYS 151
152 DHSKWNSYKSILKKEESG------LTKDVFLG---------VKYQ----------------------------------------CVE------------YAR----RFLV----IN---FAAAFKDINCADEIYK-LNYVEDLTTT--------FPNK--------GNQP-------------PQV----------------------------------GDLIIYPRTQKQ--PY--------------------------------------------------GHVAVIVE----V---GMGYVCVAEQNYEDSGWIKKNYARK 152
153 RSNYVTF-----------------DNRQVYTGVRFYTIHYYFRFQ----------------------------------------CVE------------FAR----RYLI----QT---KGVVFGDVGCAYHIFD-LNTVTDLVTQQQR-QFQSIPQ---------GSSIP------------PKK----------------------------------GDLVIYQKSGKQ--WW--------------------------------------------------GHVAVVTN----V---DGNLIDLAEQNY-DEDWDSQSYARQ 153
154 ISTQKNSIK---------------GEGSMETG---------MEWQ----------------------------------------CFE------------YVK----RYWI----MRGVPQPVILPTARKSSELWS---FTQATFKNGSKVQLERHDN---------GGSQ-------------PLV----------------------------------GDLLVYREQPAL-LPV--------------------------------------------------GHVAVIVR----V---GKTHVWVAEQNWFNKQWHPPFHNFS 154
155 FSGERS------------------IDGNLFCG---------FKYQ----------------------------------------CVE------------FAR----RWLF----ER---KSLVLPDVDWAVHIFN-LKEVSDARTGKPV-RCVAIRN---------GTAAK------------PVV----------------------------------DSLLIYPSDDYS--PV--------------------------------------------------GHVAAITE----V---GDKWVRIADQNHRFHKW-DANYAAE 155
156 FSGERS------------------IDGNLFCG---------FKYQ----------------------------------------CVE------------FAR----RWLY----EA---KGLVLPDVNWAAHIFD-LTEVHDASTATPV-PCVKVSN---------GTAAK------------PVA----------------------------------DSLLIYAVNEDA--PW--------------------------------------------------GHVAVITE----V---GDKWVRIADQN-------------- 156
157 FSGERS------------------IEGNIFFG---------FKYQ----------------------------------------CVE------------FAR----RWLL----VR---KGLVLPDVNWACHIFQ-LKEVRDAATAESF-AVLPVRN---------GTGTK------------PEA----------------------------------DALLVYPSTATN--PV--------------------------------------------------GHVGAITE----V---GDDYVCVADQN-------------- 157
158 FSGERS------------------VEDNIFFG---------FKYQ----------------------------------------CVE------------FAR----RWLL----AR---KGLVLPDVNWACHVFQ-LKEVRDAATAESF-AVLPVRN---------GAEAK------------PEA----------------------------------DALLVYPSTDTN--PV--------------------------------------------------GHVGAITE----V---GDDYVCVADQNYRFHKW-ESSYAYK 158
159 FSGERS------------------IEDNIFFG---------FKYQ----------------------------------------CVE------------FAR----RWLL----VR---KGLVLPDVNWACHIFQ-LKEVRDAATTESF-AVLPVRN---------GTKTK------------PEA----------------------------------DALLVYPSTDAN--PV--------------------------------------------------GHVGVITE----V---GDDYVCVADQNYRFHKW-ESSYAYK 159
160 FSGERN------------------IEDNIFFG---------FKYQ----------------------------------------CVE------------FAR----RWLL----VR---KGLLLPDVNWACHIFQ-LKEVRDAATTESF-AVLQVRN---------GTTTK------------PEA----------------------------------DALLVYPSTDAN--PV--------------------------------------------------GHVGTITE----V---GDDYVCVADQNYRFHKW-ESSCAYK 160
161 FSGERS------------------IEGNFFCG---------FKYQ----------------------------------------CVE------------FAR----RWLL----VR---KGLVLPNVNWACHIFQ-LKEVRDAATAEGF-AVLKVCN---------GTERK------------PEA----------------------------------DTLLIYSSTDAC--PV--------------------------------------------------GHVSVITE----V---GDDYVCVADQNYRFHKW-ESSYAYR 161
162 FSGERS------------------IDDNVFCG---------FKYQ----------------------------------------CVE------------FAR----RWLL----ER---KGLVLPDVNWACHIFK-LKSVKDAATAEEV-PVIAVRN---------GTEAK------------PEP----------------------------------DTLIIYPSSDVN--TV--------------------------------------------------GHVGAITE----V---GDDYVCIADQNYRFHKW-EASYSYK 162
163 FTYQGH------------------YADNFFMG---------YKWQ----------------------------------------CVE------------FAR----RWLL----LR---KGLALPQYDFAAHLIH-MREVCDAETGEVV-PCKFVSQ---------GSPEP------------PVA----------------------------------DALIVYPGTREN--IF--------------------------------------------------GHVGVITH----V---TDALVGVADQN-------------- 163
164 ---ENNY-----------------VDTSIYTG---------FRYQ----------------------------------------CVE------------YAR----RFLL----LT---TGCVFANCGRASEIYA-MDHITHVETGAQY-TLHRHHND--------GTATQ-----------KPAP----------------------------------GDIIVYPYHPEL-TPW--------------------------------------------------GHVGVISF----V---DDNRVGIAEQNH------------- 164
165 FSGENNY-----------------VDTSIYTG---------FRYQ----------------------------------------CVE------------YAR----RFLL----LT---TGCVFANCGRASEIYA-MDHITHVETGAQY-TLHRHHND--------GTATQ-----------KPAP----------------------------------GDIIVYPYHPEL-TPW--------------------------------------------------GHVGVISF----V---DDNRVGIAEQNHYFGPF-TSPNESY 165
166 ---ENNY-----------------VDTSIYTG---------FRYQ----------------------------------------CVE------------YAR----RFLL----LT---TGCVFANCGRASEIYA-MDHITHVETGAQY-TLHRHHND--------GTATQ-----------KPAP----------------------------------GDIIIYPYHPEL-TPW--------------------------------------------------GHVGVISF----V---DDNRVGIAEQNH------------- 166
167 FSGENNY-----------------VGTSIYTG---------FRYQ----------------------------------------CVE------------YAR----RFLL----LT---TGCVFANCGRASEIYA-MDYITHVETGALY-TLHHHNND--------GTATQ-----------KPAP----------------------------------GDIIIYPYHPEL-TPW--------------------------------------------------GHVGVISF----V---DDNRVGIAEQN-------------- 167
168 -----------------------------YTG---------YRYQ----------------------------------------CVE------------YAR----RFLI----LT---TGCVFGSCGGANEIFE-MKTLKHIETDAKL-DFIAHPN---------GKSKR-----------RPTP----------------------------------GDIIVYPRHSQL-LPW--------------------------------------------------GHVGVISY----V---HNQKVGIAEQN-------------- 168
169 ------------------------------MG---------HKWQ----------------------------------------CVE------------FAR----RFLF----LN---YGFVFTDVGMAWEIFS-LRFLRQVVNDNIL-PLQAFAN---------GSKRA------------PRA----------------------------------GALLIWQKGGEF-HET--------------------------------------------------GHVAVITQ----L---LDDKVRIAEQNVLHSPL-PLGQQWT 169
170 VPRPSR-----------DDPAFRSYIDNEYMG---------HKWQ----------------------------------------CVE------------FAR----RFLF----LT---YGFVFTDVGMAYEIFS-LRFLRQVVNDNLL-PLQAFAN---------GSRRA------------PEA----------------------------------GSLLIWQKGGEF-HET--------------------------------------------------GHVAVITQ----L---VGDKVRIAEQNVIHQPL-PQGQQWT 170
171 DPRDYA-----------DDAAFRSYIGNEYMG---------HKWQ----------------------------------------CVE------------FAR----RFLF----LN---YGVVFTDVGMAWEIFS-LRFLREVVNDNIL-PLQAFAN---------GSARA------------PVA----------------------------------GALLIWQKGGEF-KDT--------------------------------------------------GHVAIITQ----L---LDNKIRIAEQNVIHMPL-PPGQQWT 171
172 DPWD-D-----------DDAAFRSYIDDEYMG---------HKWQ----------------------------------------CVE------------FAR----RFLF----LN---YGVVFTDVGMAWEIFS-LRFLREVVNDNIL-PLQAFPN---------GSPRA------------PEA----------------------------------GALLIWQKGGEF-NET--------------------------------------------------GHVAIITQ----L---LDNKIRIAEQNVIHTPL-PPGQQWT 172
173 DPQEYE-----------DDAVFRSYIDDEYMG---------HKWQ----------------------------------------CVE------------FAR----RFLF----LN---YGVVFTDVGMAWEIFS-LRFLREVVNDNIL-PLQAFPN---------GSPRA------------PVA----------------------------------GALLIWDKGGEF-KDT--------------------------------------------------GHVAIITQ----L---HGNKVRIAEQNVIHSPL-PQGQQWT 173
174 DPREYE-----------DDSAFRSYIDDEYMG---------HKWQ----------------------------------------CVE------------FAR----RFLF----LN---YGVVFTDVGMAWEIFS-LRFLREVVNDNIL-PLQAFPN---------GSPRA------------PVA----------------------------------GALLIWDKGGEF-KDT--------------------------------------------------GHVAIITQ----L---HGNKVRIAEQNVIHTPL-PPGQQWT 174
175 DAQEYP-----------DDAAFRSYLGGEYMG---------YKWQ----------------------------------------CVE------------FAR----RYLY----LN---YGMVFTDVGMAYEIFS-LRFLRQVVNDALL-PLQAFAN---------GGKRA------------PEC----------------------------------GALLIWQEGGEF-KHT--------------------------------------------------GHVAVITE----V---LADKVRIAEQNVIHSRL-PSGQQWT 175
176 ------------------------------------------KYQ----------------------------------------CVE------------FIK----RYYF----EYYNHKMP--ATYGNAKDFYN--KELKDGEINIKR-GLLQFSN---------PSFKK------------PSV----------------------------------GDIIIFKPYILN--PY--------------------------------------------------GHVAIISN----V---EDDNIEIVQQN--VWKKTREKFKLT 176
177 ------------------------------------------KYQ----------------------------------------CVE------------FIK----RYYF----EYYNHKMP--DTYGNAKDFYD--NKLKDAEMNVKR-GLLQFSN---------PSFKK------------PSV----------------------------------GDIIIFKPSLLN--PY--------------------------------------------------GHVAIISK----V---DESAIEIIQQN-------------- 177
178 TSLGRNL-----------------SEDGYNLG---------IKYQ----------------------------------------CVE------------FIK----RFYF----QFYHHKMP--DTYGHAKDFFD--HSVADGGINKKR-ALLQFTN---------GSISA------------PET----------------------------------GDIIVFSPTLFN--RY--------------------------------------------------GHVAIVSA----V---EPTSIEIIQQN-------------- 178
179 NVDGREL-----------------TKDGYNLG---------LKYQ----------------------------------------CVE------------FVK----RYYY----DALKHKMP--DSYGHAKDFFN--PLVKDGELNTQR-NLNQFIN---------PSSAK------------PRV----------------------------------NDLLVYSGTLLN--KY--------------------------------------------------GHVAIISN----V---TANGIEIIQQN-------------- 179
180 NVDGRAL-----------------AKDGYNLG---------LKYQ----------------------------------------CVE------------FVK----RYYY----EELNHKMP--DSYGHAKDFFN--SQIKDGKINKQR-NLKQYKN---------PSKSK------------PKV----------------------------------NDLVIYSATTLN--KY--------------------------------------------------GHVSIVSK----V---TENEVEIIQQN-------------- 180
181 HVEKRNV-----------------TKDGYNLG---------LEFQ----------------------------------------CVE------------FVK----RYYY----EHLNHKMP--DSYGHAKDFFN--PKVKDGKRNVQR-NLIQYTN---------KSISK------------PKT----------------------------------NDIVVFEASWYN--RF--------------------------------------------------GHVAIVTE----V---SENTVSIIQQN-------------- 181
182 QSSGRNV------------------IDGYNVG---------IRYQ----------------------------------------CVE------------FVK----RYYY----LHYHHRMP--DTYGNAKDFFD--KKLSSGSLNTAR-GLFQYKN---------RDQVK------------PQK----------------------------------GDLLVFDSYIFN--PY--------------------------------------------------GHVAIVSN----V---TDKNIEIIQQNPGPWGRSRTNIELE 182
183 QSSGRNI------------------IDGYNVG---------VRYQ----------------------------------------CVE------------FVK----RYYY----LHYHHRMP--DTYGHAKAFFD--KKLSNGSLNTAR-ALFQYTN---------GDHVK------------PQK----------------------------------GDLLVFDSYILN--PY--------------------------------------------------GHVAIVSR----V---TDSNIEIIQQNPGPWGKSRACIELQ 183
184 QSSGRNV------------------IDGYNVG---------IRYQ----------------------------------------CVE------------FVK----RYYY----LHYHHRMP--DTYGHAKDYFD--KKISNGALNTAR-GLFQYQN---------GTQVK------------PQK----------------------------------GDLIVFASYILN--PY--------------------------------------------------GHVAIISK----V---TDKDIEIIQQNAGPWGKSRVLIELQ 184
185 --SGRNV------------------VDGYNIG---------MKYQ----------------------------------------CVE------------FVK----RYYY----EYYHHKMP--DSYGHAKSFFD--KKLSNGEMNVSR-GLIQYKN---------GEGIL------------PQI----------------------------------GDIVVFDGYLFN--PY--------------------------------------------------GHVAIISA----V---GTNEVELIQQNSGCMNVSRKCLGLT 185
186 TNEGRNL-----------------SLDGYNLG---------IKYQ----------------------------------------CVE------------FVK----RYFY----LRYQHKMP--DSFGHAKDFFN--DLLPDASWNEKR-ALRQYTN---------GSQSK------------PMA----------------------------------DDLLVFAPWMFN--PY--------------------------------------------------GHVAIVAN----V---TETSIEIAQQN-------------- 186
187 ------------------------------------------KYQ----------------------------------------CVE------------FVK----RYFY----LRYQHKMP--DSFGHAKDFFN--DLLPDASWNEKR-ALRQYTN---------GSQSK------------PMA----------------------------------DDLLVFAPWVFN--PY--------------------------------------------------GHVAIIAN----V---TETSIEIAQQN-------------- 187
188 TNEGRNL-----------------SLNGYNLG---------IKYQ----------------------------------------CVE------------FVK----RYFY----LRFQHKMP--DSFGHAKDFFN--DLLPDASWNEKR-ALRQYTN---------GSQSK------------PMA----------------------------------DDLLVFAPWMFN--PY--------------------------------------------------GHVAIVAS----V---TETSIEIAQQN-------------- 188
189 TNEGRNL-----------------SLDGYNLG---------IKYQ----------------------------------------CVE------------FVK----RYFY----QRYQHQMP--DSFGHARDFFD--NLLTDGSWNEKR-ALRQFTN---------GSQSK------------PMA----------------------------------DDLLVFAPWILN--PY--------------------------------------------------GHVAIIAA----V---TDKGIEIAQQN-------------- 189
190 TSDGRNL-----------------SIDGYNLG---------IKYQ----------------------------------------CVE------------FVK----RYFY----QRHQHKMP--DTYGHARDFFD--NSLADGAWNEKR-AMLQYVN---------GSQLT------------PQA----------------------------------DDLLAFAPWLFN--PY--------------------------------------------------GHVAIIAE----V---HDHQVEIVQQN-------------- 190
191 TSDGRNL-----------------SIDGYNLG---------IKYQ----------------------------------------CVE------------FVK----RYFY----QRHQHKMP--DTYGHARDFFD--NSLADGAWNEKR-AMLQYVN---------GSQLT------------PQA----------------------------------DDLLVFAPWLFN--PY--------------------------------------------------GHVAIIAE----V---HDHQVEIVQQN-------------- 191
192 ------------------------------------------KYQ----------------------------------------CVE------------FVK----RYYF----ERFNHRMP--DAFGNAKDFFD--ANTAQGALNPKR-ALVQYRN---------AGSEK------------PQV----------------------------------DDLIVFPPTLFN--PY--------------------------------------------------GHVAIVAN----V---TEREVEIVQQN-------------- 192
193 ENHGKSY-----------------SKDGYYYG---------YKWQ----------------------------------------CVE------------YVK----RFYY----EAKGHKMP--DVYGNAKDFFD--INTEHGHLNKRR-GLIQHRN---------GENEK------------PKV----------------------------------DDLLVFTDT-----KF--------------------------------------------------GHVVIVTE----V---GDDYIEVIQQN--MGSSSRDKFTLK 193
194 ENHGKSY-----------------SKDGYCYG---------YKWQ----------------------------------------CVE------------YVK----RFYY----EAKGHKMP--DVYGNAKDFFD--INTEQGHLNKRR-GLIQYRN---------GENEK------------PKV----------------------------------DDLLVFTDT-----QF--------------------------------------------------GHVVIVTE----V---GDDYIEVIQQN--MGSSSRDRFTLK 194
195 ENHGKSY-----------------SKDGYYYG---------YKWQ----------------------------------------CVE------------YVK----RFYY----KAKDHKMP--DVYGNAKDFFD--INTEQGHLNKRR-GLIQYRN---------GENEK------------PKV----------------------------------DDLLVFTDT-----EF--------------------------------------------------EHVVIVTE----V---GNDYIEVIQQN--IGSSSRDKFTLK 195
196 ESHGKNY-----------------SKDGYYYG---------YKWQ----------------------------------------CVE------------YIK----RFYY----EAKGHSMP--NGFGNAKDFFD--PKVGQGKLNKDR-GLFQYKN---------GENEK------------PKA----------------------------------DDILVFTDT-----KY--------------------------------------------------GHVVIVTK----V---TDDTVEVIQQN--MGNKTRDQFKLE 196
197 -----SY-----------------SNDGYYYG---------YKWQ----------------------------------------CVE------------YIK----RFFY----EAKVHKMP--DVYGNTKDFFD--QELEQCALNEKR-GLYQYKN---------GANEK------------PMK----------------------------------DDLLVFTYT-----NY--------------------------------------------------GHVVIISE----V---GDNYIEVVQQN--MGQESRDKFELT 197
198 ASHGLNY-----------------SDDGYYYG---------LKWQ----------------------------------------CTE------------YVK----RFYY----TVYQHKMP--DGAGNAKYYFN--PMLEQGEYNNQR-GLFQYKN---------GGDVK------------PRE----------------------------------DDLIVFTDG-----KY--------------------------------------------------GHVAIISA----T---GEDWIEVVQQN-------------- 198
199 --------------------SSRNSVNGYDTG---------LAYQ----------------------------------------CVE------------LVR----RFYY-------QYYGKQMGAGYNAKDFFA----------NAYRWGMTAYAN---------GGGMA------------PKP----------------------------------GDILCFN--GNAGGGA--------------------------------------------------GHVAPIVE----V---GADYVIIVQQN-------------- 199
200 ------------------------------------------KWQ----------------------------------------CVE------------FVR----RYTSMSGGKYISHR-------GNASTFYK--SSIPDGG-HTFD-AFTQYRNTDPKTGAKIGSIGK------------PKP----------------------------------GDIIVLST---N--TY--------------------------------------------------GHVAVIAE----V---GDEHISIAQQN--VLTNFKEEISLK 200
201 -------------------------GNG--------------KYQ----------------------------------------CVE------------YVK----RFYK----EAMNVE-PDWDGTGNAITYYT--NA-------EAK-GLVSYSN---------NGSVA------------PKP----------------------------------DDIIIFSPT-DN--GY--------------------------------------------------GHVAIITE----V---GDKYIKIIEQN-WNQENAFASLSLE 201
202 -------DVFCVYRKGDTGPMFYMLHGGGYSGLTWAAVTEGLLSQLRCRVVAPDLRGHGDTVTKDDQDLSTERQIEDIVAIHENICGD----------EAIPTFIIGHSMGGALAVHVAASGRLKGLIGIA---------VIDVVEGTAMEALTTMKH---------FLKSR------------PQKFGSVGAAVEWCCKSGTAKNSRAARVSMPAQIKKIGDLYTWRIDLSKTEPHWVGWFKGLSKLFLSCRVPKLLVLAGIDRLDTDLIVGQMQGKFQETIMPKAGHA--VQEDSPEELADTLANFALRNQ--------------- 202
Active site residue: X
Putative: +
Experimental: #
