Alignment for family M15C

              1         2         3             4          5                                                       6                          7                          8                                            9          10                         11                                                 12        13        14        15        16        17        18        19        20          21        22        23        24        25        26        27        28 
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   1 -------IADAGL--LEPRTRASVQAIIGDAKQ---LGI-NLMIFET-YRSKERQKALFDQG------------------------------------------ATQLKNV---GVHH---------------Y--GLACDLVKN-------------VNGQ----PSWKG-------------DFSFL------------------------R--TLG--HH----HG--L------VW----GGD-W----GEPSVP--------------------H-S-FV-----DSD----HVQRVTKGRQASLF--------------------------------------------------------------------------------------------------------------------------------------------------------   1
   2 -------------------------------------------IAET-WRSPPLQWYHWEKG-RT--RP--------------------------------GQIVTNVSDAR-TGFHY---------------W--GLAIDIVHG---------------------------------------KRGWA---------------YP---RFFEWLARYY--EA----CG--L------VA----GGY-W--------------------------------KKLK-----DWP----HGQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------   2
   3 -------------------VAVNCRTLIERAAA---RGL-PVLVVQT-VRDAEYQRYLVSMGYAARTAT----------------------------------VPTF---------HA---------------KGVGLAFDICK--N----V-------KGHEYDDPGFFT------------------------------------------AMGRLG--KE----MG--F------TW----GGD-W-------------------------------RS-FP-----DRP----HFQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------   3
   4 -------------------------------------GL--LVLVTGTVRDEEYQQYCFENG-------------------------------------------TAATPV--PSFHG---------------EQAGLAFDFCQN-------------IKGQEYSDSAFFQ------------------------------------------RAGELG--EQ----VG--F------EW----GGR-W------------------------------K-S-FP-----DRP----HLQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------   4
   5 -----------DIDRLRPDVAANCRAWLELCRA---AGL--LVLVTGTVRDEEYQQYCFENG-------------------------------------------TAATPV--PSFHG---------------EQAGLAFDFCQN-------------IKGQEYSDSAFFQ------------------------------------------RAGELG--EQ----VG--F------EW----GGR-W------------------------------K-S-FP-----DRP----HLQWSDGGKYTSSMIRAGDYPPAMPPYREEDTD-------------------------------------------------------------------------------------------------------------------------------------   5
   6 ------------------QAQKACALFLEECKK---QGL-NVLITET-YRSQERQNWLYEQG-RSRAGK----------------------------------VVTWTK----NSRHT---------------S--RRAWDICK--N----V-------RGQEYSDSSFFK------------------------------------------KCAEVA--AL----LG--I------TW----GGD-W-------------------------------NS-NP-----DTP----HFEI------------------------------------------------------------------------------------------------------------------------------------------------------------------   6
   7 -----------------------CALFLEECKK---QGL-NVLITET-YRSQERQNWLYEQG-RSRGGK----------------------------------AVTWTK----NSRHT---------------S--RRAWDICK--N----V-------KGQEYRDKTFFK------------------------------------------KCAEVA--AL----LG--I------TW----GGE-W-------------------------------KN-SP-----DTP----HFEI------------------------------------------------------------------------------------------------------------------------------------------------------------------   7
   8 -----------------------------ECER---EGL-AVLITET-YRTQERQDYLYAQG-RTRAGT----------------------------------IITWTR----KSRHT---------------G--RLAWDVCK--N----V-------KGQEYADAAFFD------------------------------------------RCGRIA--EK----LG--I------TW----GGR-W--------------------------------D-TP-----DRS----HFEV------------------------------------------------------------------------------------------------------------------------------------------------------------------   8
   9 ------------------------------------AGIQNIFVTET-YRSQARQNYLYRQG-RTRPGK----------------------------------IVTWTL----ISNHT---------------S--RLAWDIAV--A----P-------PKSLY-DVDTLT------------------------------------------KVGAIA--RK----LG--I------TW----GGD-W-------------------------------AR-RI-----DRP----HFEVKQ----------------------------------------------------------------------------------------------------------------------------------------------------------------   9
  10 -------------SELSPVAQTAIRLLFQELYK---AGIRDVFVTET-YRSQARQKYLYAQG-RTRPGN----------------------------------IVTWTL----NSNHA---------------S--RLAWDIAV--A----P-------PKSLY-DVATLN------------------------------------------KAGAIA--RK----LG--I------TW----GGD-W-------------------------------KN-NL-----DRP----HFEVKP----------------------------------------------------------------------------------------------------------------------------------------------------------------  10
  11 ---------------------------------------INIFITET-YRSQARQNYLYAQG-RTRPGQ----------------------------------IVTWTL----SSNHK---------------S--RLAWDLAV--S----P-------PQSLY-DVMTLN------------------------------------------KVGGIA--RK----LG--I------TW----GGD-W-------------------------------AG-SI-----DRP----HFEV------------------------------------------------------------------------------------------------------------------------------------------------------------------  11
  12 ------------------------------------AGIKNIFITET-YRSQERQKYLYAQG-RTRPGQ----------------------------------IVTWTL----NSNHK---------------S--RLAWDIAV--G----P-------PQSLY-DVTTLN------------------------------------------RVGAIA--KK----LG--I------EW----GGT-W-------------------------------TN-AI-----DRP----HFEVK-----------------------------------------------------------------------------------------------------------------------------------------------------------------  12
  13 ------------------------------------AGIRNIFITET-YRSQERQKYLYAQG-RTRPGQ----------------------------------IVTGTL----NSNHK---------------S--RLAWDIAV--G----P-------PQTLY-DVTTLN------------------------------------------KAGAIA--KK----LG--I------EW----GGT-W-------------------------------TN-AI-----DRP----HFEVK-----------------------------------------------------------------------------------------------------------------------------------------------------------------  13
  14 ------------------------------------AGIKNIFITET-YRSQERQKYLYAQG-RTRPGQ----------------------------------VVTWTL----NSNHK---------------S--RLAWDIAV--G----P-------PQSLY-DATTLS------------------------------------------RVGAIA--KK----LG--I------EW----GGT-W-------------------------------TK-AI-----DRP----HFEVK-----------------------------------------------------------------------------------------------------------------------------------------------------------------  14
  15 -------------------------------------GIKNIFITET-YRSQERQKYLYAQG-RTRPGQ----------------------------------VVTWIL----NSNHK---------------S--RLAWDIAV--G----P-------PQSLY-DVTTLS------------------------------------------RVGAIA--KK----LG--I------EW----GGT-W-------------------------------TK-AI-----DRP----HFEVK-----------------------------------------------------------------------------------------------------------------------------------------------------------------  15
  16 -------------------------------------GIKNIFITET-YRSQARQKYLYAQG-RTRPGK----------------------------------VVTWTL----NSNHK---------------S--RLAWDIAV--G----P-------PQSLY-DVTTLS------------------------------------------RVGAIA--KK----LG--I------EW----GGT-W-------------------------------TK-AI-----DRP----HFEVK-----------------------------------------------------------------------------------------------------------------------------------------------------------------  16
  17 ------------------------------CFK---AGIKNVFITET-YRSQERQKYLYAQG-RTRPGQ----------------------------------IVTWTL----DSNHK---------------S--RLAWDIAV--G----P-------PQDLY-DVATLS------------------------------------------RVGAIA--RK----LG--I------TW----GGD-W-------------------------------TG-NI-----DRP----HFEVKPN---------------------------------------------------------------------------------------------------------------------------------------------------------------  17
  18 ------------------------------------AGIVDIFITET-YRSQARQNYLYEQG-RTRPGQ----------------------------------VVTWTR----NSNHT---------------S--RRAWDIAV--A----P-------PRNLY-DISTLS------------------------------------------KVGAIA--KK----LG--I------EW----GGY-W------------------------------EAG-KY-----DAP----HFEIP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  18
  19 -----------------PAAEQACRLLFQECYK---AGIRNLFVSET-YRPQARQNYLYEQG-RSRSGP----------------------------------IVTWTK----TSRHT---------------S--RLAWDIAC--S----S-------PATLY-DAALLS------------------------------------------KVGAIA--RK----LD--I------TW----GGD-W-------------------------------SN-NR-----DRP----HFEVT-----------------------------------------------------------------------------------------------------------------------------------------------------------------  19
  20 ---------------------DIA-------ED---EGL-DVTIAET-YRTQERQDQLYAKG-RTSPGS----------------------------------IVTWTN----DSRHT---------------R--RNAFDIAK--N----S-------PGHEYDDPEFFR------------------------------------------KCAEIA--KR----IG--L------TA----GYY-W-------------------------------ES-NQ-----DMP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  20
  21 --------------QLSPKTRELANLFLKRCSE---EGL-EVKITET-YRTQERQNHLYELG-RSRPGV----------------------------------KVTWTK----NSKHT---------------M--RRAFDVAKIGD----D-------P---YGDEDFFK------------------------------------------KCAEIG--KE----IG--L------TP----GYY-F-------------------------------KY-FQ-----DKP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------  21
  22 ---------------LDPELRARVERVMERMKN---EYGHDVSIVET-TRSQERQDWLYEQG-RSRDGS----------------------------------VVTWTR----DSAHT---------------R--GEAVDVII----------------DGRYENAAGFG------------------------------------------RLQRIA--NE----EG--L------RT----LGM-K-----------------------------------------DPG----HLEL------------------------------------------------------------------------------------------------------------------------------------------------------------------  22
  23 --------------QLRPEVRKKVEKFLIKAQK---AGI-PLKVTSA-YRNCEEQNKLYAQG-RTAPGG----------------------------------IVTNAKCG--QSDHN---------------V--GVAVDIVPI-------------VDGR----ANYKV------PESV------WN------------------------TIGAIGES------VG--L------SW----GGR-W------------------------------T-S-FK-----DRP----HF--------------------------------------------------------------------------------------------------------------------------------------------------------------------  23
  24 ---------------------------------MVNAGI-PFMYTCT-RRTQEEQDALYAQG-R---TK---------------P--------------G-K-IVTWTR----KSKH-----------------IDGKAFDIA-I-L----R-------DFK----PCWDV-----KVDVNENEIPDYE------------------------EAGRIG--ES----VG--L------RW----GGR-F------------------------------R-N-SKGKPRPDYP----HFEI------------------------------------------------------------------------------------------------------------------------------------------------------------------  24
  25 ---------SRDLADLQPHVRSMAEQLLDTAK-A--VGI-PLTVTFT-RRSIARQAALFAQG-R---TA---------------P--------------G-P-IVTNAKSG--ESFHN---------------Y--GLALDVVPT-A----LL-----------ALPDWGD-----TPDQQARTDALWS------------------------KVGTIG--KG----IG--F------RW----GGE-F------------------------------H-S-IR-----DRP----HFEWS-----------------------------------------------------------------------------------------------------------------------------------------------------------------  25
  26 ----------------------------NAVLKLTSPDL-EVRFTCT-WRPQFEQDALYAQG-RTKPGP----------------------------------KVTWVT----NSAHNTDLPETPRGD--------AEAFDVGVF-------------EQGRYLPGANGRE-------------------------------------LALYQRLGPIG--EK----LG--L------VW----GGR-W------------------------------K-S-SP-----DFP----HYE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  26
  27 -------------SSLDPYVASLASEFLNLTRA---HNL-DVRITTG-FRSWDESDRLYAQG-RT--MP------------------------------G-P-IVSNARAG--DSYHN---------------W--GLAFDAAPF-V----------------NNQIS-ND-------------QNLYI------------------------LMGHLG--GQ----GG--L------EW----GGT-F------------------------------K-A-IV-----DYP----HYQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------  27
  28 VINYSNRPSSISLSSLNPYVALLAQRFLNLCTA---NGL-NVRVIQA-FRSWYEQDQLYTQG-RTMPGN----------------------------------IVTDAQGG--DSYHN---------------W--GLAFDCAPV-------------ENGQ----VSWND-------------ITSFN------------------------EMGRLG--QQ----VG--L------EW----GGN-W------------------------------T-S-YAITLV-DAP----HFQYTFGLSTEQL---------------------------------------------------------------------------------------------------------------------------------------------------------  28
  29 ------------------------KEFLQLTKT---NGL-DVRIYSV-FRSWSEQDRLFSLG-RW--KP------------------------------G-E-KVTNARGG--ESYHN---------------W--GLAFDAAPY-E----------------NNSIPWNN-------------IKKFK------------------------QMGYIG--EQ----LG--L------TW----GGR-F------------------------------T-T-IV-----DYP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  29
  30 ---------------------------LQLTKT---NGL-DVRIYSV-FRSWSEQDRLFSLG-RW--KP------------------------------G-E-KVTNARGG--ESYHN---------------W--GLAFDAAPY-E----------------NNSIPWNN-------------IKKFK------------------------QMGYIG--EQ----LG--L------TW----GGR-F------------------------------T-T-IV-----DYP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  30
  31 ------------------------KEFLQLTKT---NGL-DVRIYSV-FRSWSEQDRLFSLG-RW--KP------------------------------G-E-KVTNARGG--ESYHN---------------W--GLAFDAAPY-E----------------NNSIPWNN-------------IKKFK------------------------QMGYIG--EQ----LG--L------TW----GGR-F------------------------------T-T-IV-----DYP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  31
  32 ---------------LHPYVEILAKEFLKLTKT---NGL-DVRIYSV-FRSWSEQDKLFSLG-RW--KP------------------------------G-K-KVTNARGG--ESYHN---------------W--GLAFDAAPY-E----------------NNSIPWNN-------------IKKFK------------------------QMGYIG--EQ----LG--L------TW----GGR-F------------------------------T-T-IV-----DYP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  32
  33 -------------------VEMSAKEFLQLTKT---NGL-DVRIYSV-FRSWSEQDRLFSLG-RW--KP------------------------------G-K-KVTNARGG--ESYHN---------------W--GLAFDAAPY-E----------------NNSIAWNN-------------TKKFK------------------------KMGYIG--EQ----LG--L------TW----GGR-F------------------------------T-T-LV-----DYP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  33
  34 ----------------------------QLTKI---NGL-DVRIYSV-FRSWSEQDQLFSLG-RW--KP------------------------------G-K-KVTNARGG--ESYHN---------------W--RLAFDAAPY-E----------------NNSVAWNN-------------IKKFK------------------------QMGYIG--EQ----LG--L------TW----GGR-F------------------------------T-T-LV-----DYP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  34
  35 ------------------------KEFLQLTKT---NGL-DVRIYSV-FRSWSEQDRLFSLG-RW--KP------------------------------G-K-KVTNARGG--ESYHN---------------W--RLAFDAAPY-E----------------NNSVAWNN-------------IKKFK------------------------QMGYIG--EQ----LG--L------TW----GGR-F------------------------------T-T-IV-----DYP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  35
  36 ----------------------------QLTKA---NGL-DVRIYAV-FRSWSEQDQLFSLG-RW--KP------------------------------G-K-KVTNARGG--ESYHN---------------W--GLAFDAAPY-E----------------NNSIPWGD-------------IKKFK------------------------QMGYIG--EK----LG--L------TW----GGR-F------------------------------T-T-IV-----DYP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  36
  37 ----------------------------QLTKT---NGL-DVRIYSV-FRSWSEQDRLFSLG-RW--KP------------------------------G-K-KVTNARGG--ESYHN---------------W--GLAFDAAPY-E----------------NNSIPWGD-------------IKKFK------------------------QMGYIG--EK----LG--L------TW----GGR-F------------------------------T-T-IV-----DYP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  37
  38 ----------------------------QLTKA---NGL-DVRIYSV-FRSWSEQDRLFSLG-RW--KP------------------------------G-K-KVTNARGG--ESYHN---------------W--GLAFDAAPY-E----------------NNSIPWGN-------------IKKFK------------------------QMGYVG--EK----LG--L------TW----GGR-F------------------------------T-S-IV-----DYP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  38
  39 --------------------------FLELTKA---NGL-DVRIYSA-FRSWSEQDRLFSLG-RW--QP------------------------------G-K-KVTNARGG--ESYHN---------------W--GLAFDAAPY-E----------------NNSIPWGN-------------IQKFK------------------------QMGYIG--EK----LG--L------NW----GGR-F------------------------------T-T-LV-----DYP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  39
  40 ----------------------------QLTKA---NGL-DVRIYSV-FRSWSEQDQLFSLG-RW--KP------------------------------G-K-KVTNARGG--ESYHN---------------W--GLAFDAAPY-E----------------NNSIPWGN-------------IKKFQ------------------------QMGNIG--EK----LG--L------NW----GGR-F------------------------------T-S-II-----DYP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  40
  41 -SKYEFYTSSNNIHSLHPYVKRLTKEFLDLTKA---NGL-DVRIYSV-FRSWSEQDRLFSLG-RW--KP------------------------------G-K-KVTNSRGG--ESYHN---------------W--GLAFDAAPF-E----------------NETIPWGN-------------IKKFK------------------------QMGYLG--QN----LG--L------KW----GGN-F------------------------------T-S-IV-----DYP----HFEYSF----------------------------------------------------------------------------------------------------------------------------------------------------------------  41
  42 ----------LDNVNINREMARLATDVISRARM---EGM-DMRVVSD-FRSVEEQNALFAQG-R---TA---------------P--------------G-R-VVTNATGG--SSWHN---------------Y--GLAVDVAFN-N----A-------NGQ----PSWPE-------------NANWD------------------------RYGEIA--VQ----RG--L------EW----GGN-W------------------------------R-G-IN-----DRP----HIEYHPGLGAGEARTMLPAYRQGGLDQVWNNLGL------------------------------------------------------------------------------------------------------------------------------------  42
  43 -------------------------QLITDAYNK--KKY-KLVIGEG-YRSIAYQNELYARG-R---TT---------------P--------------G-P-IVTNARGG--SSFHN---------------F--GLAFDIAIL-D----K-------EED--GI-DNTD-----SK---------YR------------------------EVGKLG--KA----LG--L------EW----GGD-W------------------------------K-S-IY-----DAP----HFQF------------------------------------------------------------------------------------------------------------------------------------------------------------------  43
  44 -------------------------QLITDAYNK--KKY-KLVIGEG-YRSIAYQNELYARG-R---TT---------------P--------------G-P-IVTNARGG--SSFHN---------------F--GLAFDIAIL-D----K-------EED--GI-DNTD-----SK---------YR------------------------EVGKLG--KA----LG--L------EW----GGD-W------------------------------K-S-IY-----DAP----HFQF------------------------------------------------------------------------------------------------------------------------------------------------------------------  44
  45 -------------------------QLITDAYNK--KKY-KLVIGEG-YRSIAYQNELYARG-R---TT---------------P--------------G-P-IVTNARGG--SSFHN---------------F--GLAFDIAIL-D----K-------EED--GI-DNTD-----SK---------YR------------------------EVGKLG--KA----LG--L------EW----GGD-W------------------------------K-S-IY-----DAP----HFQF------------------------------------------------------------------------------------------------------------------------------------------------------------------  45
  46 -----------------PSVQACALQLITKAY-A--KGY-KLIITQG-LRTIYEQNKLYAKG-R---TTAQLRAVGISGIAGNPS--------------A-A-IVTRAKGG--TSYHN---------------Y--GLAFDIGIL-R----T-------DEK--DV-DWTD-----SK---------YR------------------------PIGALG--KE----LG--L------EW----GGD-F------------------------------K-S-IK-----DTP----HYQLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------  46
  47 -----------------PSVQACALQLITKAY-A--KGY-KLIITQG-LRTIYEQNKLYAKG-R---TTAQLRAVGISGIAGNPS--------------A-A-IVTRAKGG--TSYHN---------------Y--GLAFDIGIL-R----T-------DEK--DV-DWTD-----SK---------YR------------------------PIGALG--KE----LG--L------EW----GGD-F------------------------------K-S-IK-----DTP----HYQLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------  47
  48 ----------------------LIRKFINEVYAK--HQV-QLVIVQD-YRTYAQQDALYAKG-R---TT---------------P--------------G-S-IVTRARGG--QSNHN---------------F--ALAVD--V--F----PLW----EDGK--LHMDAKS-----DA----KNIQILR------------------------KVAPVG--KS----IG--L------EW----GGD-W------------------------------K-S-IV-----DNP----HFQLK-----------------------------------------------------------------------------------------------------------------------------------------------------------------  48
  49 ----------------------LIRKFINEVYAK--HQV-QLVIVQD-YRTYAQQDALYAKG-R---TT---------------P--------------G-S-IVTRARGG--QSNHN---------------F--ALAVD--V--F----PLW----EDGK--LHMDAKS-----DA----KNIQILR------------------------KVAPVG--KS----IG--L------EW----GGD-W------------------------------K-S-IV-----DNP----HFQLK-----------------------------------------------------------------------------------------------------------------------------------------------------------------  49
  50 ----------------------LIRKFINEVYAK--HQV-QLVIVQD-YRTYAQQDALYAKG-R---TT---------------S--------------G-S-IVTRARGG--QSNHN---------------F--ALAVD--V--F----PLW----EDGK--LHMDAKS-----DA----KNIQILR------------------------KVAPVG--KS----IG--L------EW----GGD-W------------------------------K-S-IV-----DNP----HFQLK-----------------------------------------------------------------------------------------------------------------------------------------------------------------  50
  51 --------------------------------AQ--HQV-QLVIVQD-YRTYAQQDALYAKG-R---TA---------------P--------------G-S-IVTKARGG--QSNHN---------------F--ALAVD--V--F----PLW----EDGK--LHMDAKS-----DA----KNIKILK------------------------KVAPVG--KS----IG--L------EW----GGD-W------------------------------K-S-IV-----DNP----HFQLK-----------------------------------------------------------------------------------------------------------------------------------------------------------------  51
  52 -------------------------------------QI-QLVIVQD-YRTYAQQDALYAKG-R---TT---------------S--------------G-R-IVTKAKGG--QSNHN---------------F--ALAVD--I--F----PLW----SDGK--LHMDAKS-----DA----ENIKILK------------------------KVAPIG--KS----IG--L------EW----GGD-W------------------------------K-S-IT-----DNP----HFQLK-----------------------------------------------------------------------------------------------------------------------------------------------------------------  52
  53 ---------------------------------K--HQI-QLVIVQD-YRTYEQQDALYAKG-R---TT---------------S--------------G-R-IVTKAKGG--QSNHN---------------F--ALAVD--I--F----PLW----ADGK--LHMDAKS-----DA----ENIKILK------------------------KVAPIG--KS----IG--L------EW----GGD-W------------------------------K-S-IT-----DNP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------  53
  54 ----VSQRNEKSIAKLHPQVRDKIRKFINDVYTK--HQV-QLVIVQD-YRTYVQQDALYAKG-R---TA---------------S--------------G-S-VVTNARGG--QSNHN---------------F--ALAVD--V--F----PLW----EDGK--LHMDVKS-----DQ----KNIKILK------------------------KIAPIG--KG----IG--L------EW----GGN-W------------------------------K-S-II-----DNP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------  54
  55 ----VSQRNEKSIAKLHPQVRDKIRKFINDVYTK--HQV-QLVIVQD-YRTYAQQDALYAKG-R---TA---------------S--------------G-S-VVTNARGG--QSNHN---------------F--ALAVD--V--F----PLW----EDGK--LHMDVKS-----DQ----KNIKILK------------------------KIAPIG--KG----IG--L------EW----GGD-W------------------------------K-S-II-----DNP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------  55
  56 ----------------------------NDSERE--LGI-KLIIVQG-LRTYEEQNKLYAKG-R---TA---------------S--------------G-S-IVTKAKGG--QSNHN---------------F--GVAID--V--F----PLH----EDGK--LHM--AD-----DK----KNIRLLK------------------------KVAPIG--KR----HG--F------KW----GGD-W------------------------------T-S-FK-----DYP----HFE-------------------------------------------------------------------------------------------------------------------------------------------------------------------  56
  57 -------------------------------AG---FPY-LVKIISG-TRTYAEQDDLYAKG-RWGGPP------------------------------G-P-KVTWAKGG--QSNHN---------------F--GIAWDVALF-E------------DGRYMNGDAAHD-------------AQAYR------------------------DLAGLA--LL----PG--L------EW----GGA-W------------------------------K-K--S-----DPP----HYQV------------------------------------------------------------------------------------------------------------------------------------------------------------------  57
  58 ----------------------------SNAAA---FPF-TVRIISG-TRTYAEQDDLYARG-RW-GRA------------------------------G-P-KVTNAKGG--QSNHN---------------F--GIAWDVALF-E------------GGRYMDGSATHD-------------AQAYR------------------------DLAGHA--LV----DG--L------EW----GGA-W------------------------------R-T-YR-----DPP----HYQV------------------------------------------------------------------------------------------------------------------------------------------------------------------  58
  59 --------ISTLLPEAQKAARQWFKLARNEAAN---QGY-EAKIICG-TRTYAEQNDLY--------RQ------------------------------R-P-KVTNARGG--QSWHN---------------F--GLAWDFGIF-Q------------DRNYLP-----N-------------HPLYT------------------------TLGKLYA-KI----DG--L------EW----GGT-W------------------------------K-S-FT-----DPP----HLQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------  59
  60 -------------------------------------------IISG-TRTYAEQDELYAIG-RTTELH------------------------------R-S-PVTKARGG--HSNHN---------------F--GIAWDVGIF-D----A-------EGRYLTGNTADQ-------------SATYA------------------------ALGKHIKDRV----TA--I------EW----GGD-W------------------------------H-S-FI-----DRP----HYQL------------------------------------------------------------------------------------------------------------------------------------------------------------------  60
  61 ----FDTRSEQNICTLSLRAQRLCRIFLTRVLQ---GGM-RVRVISG-TRTYKEQDELFRRG-RY--GN---------------P--------------G-P-RVTNARGG--RSNHN---------------F--GIAWDIGIF-T----A-------EGG------------------YVTGRDDYD------------------------EAARIG--LT----PD--I------EW----GGH-W------------------------------K-S-FP-----DRP----HYQLRF----------------------------------------------------------------------------------------------------------------------------------------------------------------  61
  62 -----------------PQVQPMARALVQKAAAS---GI-AIRVISG-LRTYEEQDALYAQG-R---TA---------------P--------------G-S-VVTNARGG--YSNHN---------------F--GIAFDIGV--F------------EGN--RYLGDSP-----K----------YK------------------------AVGVLG--MD----LG--L------EW----GGN-W------------------------------K-T-IV-----DQP----HYQLRP----------------------------------------------------------------------------------------------------------------------------------------------------------------  62
  63 ------------IATLLPQVQPMARALVQKAAAS---GI-AIRVISG-LRTYEEQDALYAQG-R---TA---------------P--------------G-S-VVTNARGG--YSNHN---------------F--GIAFDIGV--F------------EGN--RYLGDSP-----K----------YK------------------------AVGVLG--MD----LG--L------EW----GGN-W------------------------------K-T-IV-----DQP----HYQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------  63
  64 ------------IATLLPQVQPLARALVQKAALS---GI-SIKIICG-FRTYAEQDALYAQG-R---TV---------------P--------------G-N-KVTNAKGG--FSNHN---------------F--GIAFDIGV--F------------EGN--KYLGDSP-----K----------YK------------------------AVGVIG--TD----LG--L------EW----GGN-W------------------------------K-T-IV-----DEP----HFQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------  64
  65 ------------------------RALVQKATAA---GI-RIKVISA-LRTYAEQDQLYAQG-R---TA---------------P--------------G-T-VVTNAKAG--QSNHN---------------F--GIAFDVGV--F------------EGN--KYLGDSP-----K----------YK------------------------AVGALG--IE----LG--L------EW----GGN-W------------------------------K-S-IV-----DQP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------  65
  66 -------------------VRPYARELLFKAAAA---GI-RIKIISG-LRTYEEQNRLYAKG-R---TI---------------P--------------NTS-IVTNAQGG--ESNHN---------------F--GIAFDIGV--F------------EGS--KYLDDSP-----K----------YK------------------------AVGVLG--KE----LG--L------EW----GGN-W------------------------------K-S-IV-----DQP----HFQLRP----------------------------------------------------------------------------------------------------------------------------------------------------------------  66
  67 ------------IATLVPEVRGYARTLVQRAAAM---GV-EIKVISG-TRTYEAQDALYAQG-R---TA---------------P--------------G-S-IVTKARGG--YSNHN---------------F--GIAFDIGV--F------------EGT--EYIGESP-----K----------YA------------------------AVAAIA--KD----LG--L------EW----GGD-W------------------------------K-S-IQ-----DQP----HFQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------  67
  68 -------------------------------GR---QGL-QIKIGET-LRTVEEQDALYAQG-R---TR---------------P--------------G-N-IVTNAPGSSYSSYHQ---------------W--GTAFDIYRN--------------DGT------G----------AYNDAGSFFS------------------------KVGAIG--VS----LG--L------EW----GGN-W------------------------------K-S-IV-----DKP----HFQLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  68
  69 --------------------QAMAGRLIEECGR---QGL-QIKIGET-LRTVEEQDALYAQG-R---TR---------------P--------------G-N-IVTNAPGSSYSSYHQ---------------W--GTAFDIYRN--------------DGT------G----------AYNDAGSFFS------------------------KVGAIG--VS----LG--L------EW----GGN-W------------------------------K-S-IV-----DKP----HFQLPDWGSSTVG---------------------------------------------------------------------------------------------------------------------------------------------------------  69
  70 -----------------PRLQHLAGQLIEECGR---QGL-SIKIGET-FRTVAEQDALFAQG-R---TK---------------P--------------G-N-IVTNAPGSNYSSYHQ---------------W--GTAFDIYRN--------------DGA------G----------AYNDSALFFQ------------------------RVGAIG--MS----LG--L------EW----GGN-W------------------------------K-S-IM-----DNP----HFQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------  70
  71 -----------------------------ECNK---QGL-KIKIGET-LRTVAEQDALYAQG-R---TK---------------P--------------G-N-IVTNAPGSSYSSYHQ---------------W--GTAFDIFRN--------------DGT------G----------AYNEIGGFFN------------------------RVGAIG--VS----LG--L------EW----GGN-W------------------------------K-S-PV-----DKP----HFQLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  71
  72 -------KDMRDITLCHPRLQALAERLVEECNK---QGL-KIKIGET-LRTVAEQDALYAQG-R---TE---------------P--------------G-P-IVTNAPGSSYSSYHQ---------------W--GTAFDFFRN--------------DGR------G----------AYYDNDGFFT------------------------KVGKIG--VS----LG--L------EW----GGN-W------------------------------K-S-PV-----DKP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------  72
  73 ----------------------------EECSK---QGL-IIMIGET-YRTVAEQDALYAQG-R---TT---------------P--------------G-N-IVTNAPGSTYSSYHQ---------------W--GTAFDFFRN--------------DGQ------G----------AYNEAGNFFG------------------------RVGAIG--VS----LG--L------EW----GGN-W------------------------------K-S-PV-----DKP----HFQLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  73
  74 ---------MRDITLCHPRLQTLAAELIRKCAE---QGL-QIKIGET-LRTTAEQDALYAQG-R---TK---------------P--------------G-K-IVTNAKGSSYSSYHQ---------------W--GTAFDIYRA--------------DGC------G----------AYYDKDGFFS------------------------KVGAIG--VS----IG--L------EW----GGS-W------------------------------K-S-IV-----DKP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------  74
  75 ---------MRDITLCHPRLQKLATELIQKCSA---QGL-QIKIGET-LRTGSEQDTLYAQG-R---TT---------------P--------------G-S-IVTNAPGSSYSSYHQ---------------R--GTAFDIYRA--------------DGC------G----------AYYDKDGFFT------------------------RVGAIG--VS----IG--L------EW----GGN-W------------------------------K-S-IV-----DKP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------  75
  76 -----------------------AGRLEEECRT---RGL-SIKIGET-YRTVLEQENLYAQG-R---TK---------------P--------------G-D-IVTNARGITYDSFHQ---------------W--GTAFDFYRN--------------DGR------G----------AYNEEGQFFE------------------------KVGAIG--ES----LG--L------EW----GGS-W------------------------------K-S-IK-----DKP----HFQLPDWGSGTEEIKKLYKTPDEFKKTWTSKT--------------------------------------------------------------------------------------------------------------------------------------  76
  77 --------------------QKLAKELVTVCEK---QGC-PIGIGEC-FRTVQEQNRLYDQG-R---TK---------------P--------------G-P-VVTNAPGSTYRSMHQ---------------W--GVAFDVYRK--------------DGK------G----------AYNESGNYFQ------------------------RVGAIG--KS----LG--L------EW----GGD-W------------------------------K-S-IV-----DKL----HFQLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  77
  78 --------------ELHPRLQEKVSELQKLCEN---NGL-IIGIGEC-LRTVAEQEELYAQG-R---DK---------------P--------------G-N-IVTNARGTSYSSQHQ---------------W--GIAFDFYRN--------------DGT------G----------AYNESGNFFE------------------------RVGSLA--KS----IG--L------GW----GGD-W------------------------------T-S-IK-----DRP----HLYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  78
  79 -----------------------------ICEK---NGL-KIGIGEC-LRTVAEQDALYAKG-R---TQ---------------P--------------G-K-RVTNARGSTYASQHQ---------------W--GIAFDFYRN--------------DGT------G----------AYNETGDFFN------------------------RVGALA--KT----IG--L------GW----GGD-W------------------------------K-S-PV-----DKP----HLYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  79
  80 ---------------------------VEECKK---QGL-IIKIGEC-YRTVAEQEELYAQG-R---KK---------------P--------------G-N-IVTNARGSSYSSQHQ---------------W--GIAFDFFRN--------------DGN------G----------AYNESGNFFG------------------------KVGAIG--KK----LG--L------GW----GGD-W------------------------------H-S-IV-----DKP----HLYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  80
  81 --------------------------LVEECKK---QGL-IIKVGEC-FRTVAEQEELYAQG-R---TK---------------P--------------G-N-IVTNARGSSYSSQHQ---------------W--GIAFDFFRN--------------DGN------G----------AYNESGNFFG------------------------KVGAIG--KQ----LG--L------GW----GGD-W------------------------------H-S-IV-----DKP----HLYLPD----------------------------------------------------------------------------------------------------------------------------------------------------------------  81
  82 ---------------------------VEECKK---QGL-IIKIGEC-YRTVVEQDELYAQG-R---TK---------------P--------------G-N-IVTNARGSSYSSQHQ---------------W--GIAFDFFRN--------------DGN------G----------AYNESGNFFG------------------------KVGAIG--KK----LG--L------GW----GGD-W------------------------------K-S-IV-----DKP----HLYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  82
  83 ----------------HPRLQEAFKQLAVKCNA---QGL-TIGLGEC-FRTVAEQDALYEQG-R---TK---------------P--------------G-N-IVTNARGSSYSSQHQ---------------W--GIAFDFYRN--------------DGQ------G----------AYNESGDFFR------------------------RVGQVA--KS----LG--L------GW----GGD-W------------------------------T-S-IV-----DKP----HIYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  83
  84 ----------------HPSLQAAFKELAAKCHA---QGL-IIGLGEC-FRTVAEQDALYAQG-R---TE---------------P--------------G-S-IVTNAKGSSYSSQHQ---------------W--GIAFDFYRN--------------DGK------G----------AYNESGDFFR------------------------RIGQIA--KS----IG--L------GW----GGD-W------------------------------T-S-IV-----DKP----HIYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  84
  85 ----------------HPRLQEAFQQLLAKCSA---QGL-AVGLGEC-FRTVAEQDALYAQG-R---TK---------------P--------------G-S-IVTNAKGSSYASQHQ---------------W--GIAFDFYRN--------------DGK------G----------AYNESDRFFE------------------------RVGAAG--KS----LG--L------GW----GGD-W------------------------------N-S-LV-----DKP----HFYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  85
  86 ---------------LHPRLQTKAALLKEECKK---QGI-SILFSEC-LRTKAEQDALYAQG-R---TA---------------P--------------G-N-IVTNAKGSTYSSQHQ---------------W--GIAIDFYIN-M----D------VDGD------GDK-----KDDAFNNSTGLFE------------------------QVGAIA--KS----VG--L------GW----GGD-W------------------------------T-S-IK-----DRP----HLYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  86
  87 -----------------------------------------IRITEE-TRTVERQDELYAIG-R---TT---------------K--------------G-D-IVTYAKGSSYSSHHQ---------------W--GTAFDFCRN--------------DGK------D----------PFYDKDGFFS------------------------RVGEIG--KS----IG--L------EW----GGD-W------------------------------K-K--A-----DKP----HFQLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  87
  88 --------------DIHPKLKILQKKLIEECES---KGL-LIRITQE-IRTAEEQDRLYAQG-R---TT---------------S--------------G-N-IVTNARGSDYSSHHQ---------------W--GTAFDFCRN--------------DGN------D----------PYYDKDGFFS------------------------KVGAIG--KS----IG--L------EW----GGD-W------------------------------K-K-PV-----DKP----HFQLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  88
  89 -----------NVSRLHPRLKRLQKKLIAQCAA---RGL-PIRITQE-VRTAEEQDALYALG-R---TA---------------G--------------G-S-IVTNARGSSYSSHHQ---------------W--GTAFDFCRD--------------DGK------P----------PYEDGDRFFE------------------------KVGAMG--KA----LG--L------EW----GGD-W------------------------------K-S-IV-----DKP----HFQLPDWGSGT-----------------------------------------------------------------------------------------------------------------------------------------------------------  89
  90 -------------------------AWIKACAT---EGI-TVDIGET-LRTVAEQDALYAQG-R---TK---------------P--------------G-N-IVTNAKGSSYSSQHQ---------------W--GIAFDFYLK-M----D------VDGD------GSV-----SDDAYNDSTGMFK------------------------KAAELA--KA----LG--L------AW----GGD-W------------------------------R-S-IV-----DKP----HLYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  90
  91 --------------------------WMKACVT---QGI-AVTIGET-FRTVAEQDALYAQG-R---TK---------------P--------------G-K-KVTNAPGSSYSSQHQ---------------W--GIAFDFYLI-M----D------IDGD------GST-----SDDAFNDRTGMFK------------------------KAAEIA--KG----LG--L------AW----GGD-W------------------------------K-S-LE-----DKP----HLYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  91
  92 ------------------RMQKIAAQWITACKA---EGI-NVAISET-LRTAAEQDALYAKG-R---TK---------------P--------------G-N-IVTNAKGSSYRSQHQ---------------W--GIAFDFYLK-M----D------VDGD------GKI-----ADDAYNDSKGHFR------------------------KAAEIG--KK----LG--L------AW----GGD-W------------------------------S-S-IV-----DKP----HLYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  92
  93 -----------------------ATQWQKECLD---QGI-IVEIGET-LRTVKEQDALYEQG-R---TK---------------P--------------G-P-IVTNAKGSSYSSQHQ---------------W--GIAFDFFLK-M----D------INGN------GAV-----TDDAFNDSTGMFE------------------------RAASVA--EK----LG--L------GW----GGR-W------------------------------T-S-IV-----DKP----HLYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  93
  94 -----------------------ATQWQKECLD---QGI-IVEIGET-LRTVKEQDALYEQG-R---TK---------------P--------------G-P-IVTNAKGSSYSSQHQ---------------W--GIAFDFFLK-M----D------INGN------GAV-----TDDAFNDSTGMFE------------------------RAASVA--EK----LG--L------GW----GGR-W------------------------------T-S-IV-----DKP----HLYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  94
  95 ----------------HPRLQHLATQWQKECLD---QGI-IVEIGET-LRTVKEQDALYEQG-R---TK---------------P--------------G-P-IVTNAKGSSYSSQHQ---------------W--GIAFDFFLK-M----D------INGN------GAV-----TDDAFNDSTGMFE------------------------RAASVA--EK----LG--L------GW----GGR-W------------------------------T-S-IV-----DKP----HL--------------------------------------------------------------------------------------------------------------------------------------------------------------------  95
  96 --------------KLHPWLDQKLTVLLRKCAK---KGI-YLIITEG-FRSKEYQDSLYAQG-R---TK---------------P--------------G-K-IVTNAKGSTYSSQHM---------------W--GVAFDIAIN-D----S---------------------------KLLYDAATIR------------------------KVAVIA--KG----IG--L------GW----GGD-W------------------------------K-S-IV-----DTP----HFYLP-----------------------------------------------------------------------------------------------------------------------------------------------------------------  96
  97 ----------------------------KKCAK---KGL-YLIITEG-FRSKEYQDSLYAKG-R---TK---------------P--------------G-K-IVTNAKGSTYSSQHM---------------W--GIAFDIAIN-D----S---------------------------KLLYDTATIK------------------------KVAVIA--KK----IG--L------GW----GGD-W------------------------------T-S-IV-----DTP----HFYL------------------------------------------------------------------------------------------------------------------------------------------------------------------  97
  98 -----------------------------KCAK---KRI-YLIITEG-YRSKAYQDALYAKG-R---TK---------------P--------------G-K-VVTNAKGSTYSSQHM---------------W--GIAFDIAIN-D----S---------------------------RLLYDHAMLK------------------------KVAKIA--KK----IG--L------GW----GGD-W------------------------------R-S-IV-----DTP----HFYL------------------------------------------------------------------------------------------------------------------------------------------------------------------  98
  99 --------------QLHPWMQYKIYLLKKECKK---QGL-QLGIGEC-FRSVKEQEDLYAKG-R---SA---------------P--------------G-K-IVTNARGKSFSSQHQ---------------W--GIAVDIFQN-I----R---------------------------GKEYEDAFMK------------------------KVAKIAKSKK----VG--L------SW----GGD-W------------------------------K-S-PV-----DTP----HFY-------------------------------------------------------------------------------------------------------------------------------------------------------------------  99
 100 ---------------IQNDVVAF---IID-AQ-N--QGI-KVRITDG-FRSYAEQDALYAQG-R---TT---------------S--------------G-S-IVTNAKAG--QSWHN---------------F--GLAIDVVEI-V----NG-----------A---------------AQYTDASYA------------------------KIAVIG--KQ----HG--F------VW----GGD-W------------------------------T-S-FK-----DKP----HFEKTYSYTLSQLDA------------------------------------------------------------------------------------------------------------------------------------------------------- 100
 101 -------------------------------------GI-KLRVTSA-LRTVAEQDALYKKD-N----------------------------------------VTKAQGG--QSYHN---------------Y--GLAIDVVEI-K------------NGQ----VIWNC--------------D-WP------------------------KIAAVG--KR----FG--F------EW----GGD-W------------------------------K-G-FV-----DKP----HFQMPFGKSIRQLCIAKYP--------------------------------------------------------------------------------------------------------------------------------------------------- 101
 102 ----------------------------------------DIRIVQG-LRTIEEQDALYNQG-R---NG--------------NS--------------G-K-KVTDAKGG--SSYHN---------------F--GLAIDIG-R-I----T-------NNQ----LSY---------------DIDWQ------------------------KVEEIG--NE----YG--F------EW----GGN-W------------------------------T-S-II-----DKP----HFQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 102
 103 ---------------------QQAINFINDVEKE--FGV-QLRVTTG-LRTFDEQNRLYNQG-R---TT---------------P--------------G-K-IVTWVRGG--YSYHN---------------Y--GLAIDVIEI-K------------NKK----ANWDE--------------KVLI------------------------RISSVG--IR----HG--F------SW----GGD-W------------------------------K-K-QK-----DYP----HFEIT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 103
 104 --------------GLHPLVADKARALIRKAY-E--EGI-YIIITQG-FRTIEEQNRLYALG-R---TK---------------P--------------G-R-IVTNARGG--YSYHN---------------F--GLAFDVCVC-N----V------FKGT--LIPSWSL-----DR--------RWF------------------------RVGQIG--KS----LG--L------EW----GGD-W------------------------------K-S-FK-----DYP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 104
 105 --------------GLHPLVADKARALIRKAY-E--EGI-YIIITQG-FRTVEEQNRLYALG-R---TK---------------P--------------G-R-IVTNARGG--YSYHN---------------F--GLAFDVCVC-N----V------FKGT--LIPSWSL-----DR--------RWF------------------------RVGQIG--KS----LG--L------EW----GGD-W------------------------------K-S-FK-----DYP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 105
 106 ----LLFRAEKRLSGLHPLVADKARALIRKAY-E--EGI-YIIITQG-FRTVEEQNRLYALG-R---TK---------------P--------------G-R-IVTNARGG--YSYHN---------------F--GLAFDVCVC-N----V------FKGT--LIPSWSL-----DR--------RWF------------------------RVGQIG--KS----LG--L------EW----GGD-W------------------------------K-S-FK-----DYP----HFQYTFGLSLAQLRAGKRPPAA------------------------------------------------------------------------------------------------------------------------------------------------ 106
 107 ---------------VHPLVADKARALIRKAY-E--EGI-YIIITQG-FRTIEEQNRLYALG-R---TK---------------P--------------G-R-IVTNARGG--YSYHN---------------F--GLAFDICVC-N----V------FKGT--LIPSWSL-----DR--------RWF------------------------RVGQIG--KS----LG--L------EW----GGD-W------------------------------K-S-FK-----DYP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 107
 108 ----LLFRAEKRLSGLHPLVADKARALIRKAY-E--EGI-YIIITQG-FRTIEEQNRLYALG-R---TK---------------P--------------G-R-IVTNARGG--YSYHN---------------F--GLAFDICVC-N----V------FKGT--LIPSWSL-----DR--------RWF------------------------RVGQIG--KS----LG--L------EW----GGD-W------------------------------K-S-FK-----DYP----HFQYTFGLSLAQLRAGKRPPTA------------------------------------------------------------------------------------------------------------------------------------------------ 108
 109 ----LLFRAEKRLSGLHPLVADKARALIRKAY-E--EGI-YIIITQG-FRTIEEQNRLYALG-R---TK---------------P--------------G-R-IVTNARGG--YSYHN---------------F--GLAFDICVC-N----V------FKGT--LIPSWSL-----DR--------RWF------------------------RVGQIG--KS----LG--L------EW----GGD-W------------------------------K-S-FK-----DYP----HFQYTFGLSLAQLRAGKRPPTA------------------------------------------------------------------------------------------------------------------------------------------------ 109
 110 ----LLNRAEKKLAGLHPVVAEKARKLIKEAY-S--EGI-YIIITQG-FRTIEEQNSLYAQG-R---TK---------------P--------------G-K-IVTNARGG--YSYHN---------------F--GLAFDFCVC-D----V------VKGS--LEPNWKV-----DR--------RWL------------------------RVGEIG--KS----LG--L------EW----GGD-W------------------------------K-S-FK-----DYP----HFQYTFGLSRAQLRSGKKPP-------------------------------------------------------------------------------------------------------------------------------------------------- 110
 111 --------------GLHPVVAEKARQLIQQTC-T--EGI-PIIITQG-LRTIEEQDRLYAQG-R---TK---------------P--------------G-N-IVTNARGG--YSYHN---------------F--GLAFDVCVC-D----V------VKGN--LVPNWKV-----DR--------RWH------------------------RVGQIG--KS----LG--L------EW----GGD-W------------------------------R-R-LR-----DYP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 111
 112 ----LLQRAEKKLSGLHPVVAEKARQLIQQTC-T--EGI-PIIITQG-LRTIEEQDRLYAQG-R---TK---------------P--------------G-N-IVTNARGG--YSYHN---------------F--GLAFDVCVC-D----V------VKGN--LVPNWKV-----DR--------RWH------------------------RVGQIG--KS----LG--L------EW----GGD-W------------------------------R-R-LR-----DYP----HFQYTFGLTLAQLRNGKKPP-------------------------------------------------------------------------------------------------------------------------------------------------- 112
 113 ----LLQRAEKKLSGLHPVVAEKARQLIQQTC-T--EGI-PIIITQG-LRTIEEQDRLYAQG-R---TK---------------P--------------G-N-IVTNARGG--YSYHN---------------F--GLAFDVCVC-D----V------VKGN--LVPNWKV-----DR--------RWH------------------------RVGQIG--KS----LG--L------EW----GGD-W------------------------------R-R-LR-----DYP----HFQYTFGLTLAQLRNGKKPP-------------------------------------------------------------------------------------------------------------------------------------------------- 113
 114 ---------------VHPVVAAKARQLIEKAY-R--EGI-NVIVTQG-LRTIEEQNELYAQG-R---TK---------------P--------------G-K-IVTNAKGG--YSYHN---------------F--GLAFDFAIM-K----D-------DGN--I--SWNV-----DD--------KWK------------------------RVAQIG--KS----LG--L------EW----GGD-W------------------------------K-S-FP-----DYP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 114
 115 ----------------HPLVAAKARQLIEQAY-K--EGI-NVIITQG-LRTIEEQNELYAQG-R---TK---------------P--------------G-K-IVTNAKGG--YSYHN---------------F--GLAFDFALL-N----P-------DGS--V--SWNV-----DD--------KWK------------------------RVAQIG--KS----LD--L------EW----GGD-W------------------------------K-D-FK-----DYP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 115
 116 ----LLEKADKKLQGVHPTVAAKARQLVSLAY-K--EGI-PIIITQG-LRTIEEQNALYAQG-R---AK---------------P--------------G-K-IVTNAKGG--YSYHN---------------F--GLAFDFAIL-N----A-------NGS--V--NWNV-----DD--------KWK------------------------RVGAIG--KS----LG--L------EW----GGD-W------------------------------T-S-FK-----DYP----HFQYTFGLSLADLRSGKKPP-------------------------------------------------------------------------------------------------------------------------------------------------- 116
 117 ------------------------------------LGF-TLRVTQG-RRNIAEQNGFYAQG-R---TK---------------P--------------G-K-IITNAKGG--YSYHN---------------F--GLALDVVVI-K------------NGQ--A--DWTV-----LN--------K--------------------------DIVRIA--KE----EG--F------EW----GGD-W------------------------------K-S-FK-----DYP----HFQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 117
 118 ----------------------KSYELIRQAY-K--ESI-FVVITEG-FRSIEQQHKLYSQG-R---TT---------------P--------------G-S-IVTNAKGG--YSYHN---------------Y--GLAFDIALL-D----N-------NGE--V--DWTI-----DR--------RWN------------------------KAGEIG--KR----IG--L------EW----GGD-W------------------------------K-S-LK-----DYP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 118
 119 ----LLKKAENKLQNVHEIVQEKSYELIRQAY-K--ESI-FVVITEG-FRSIEQQHKLYSKG-R---AT---------------P--------------G-S-IVTNAKGG--YSYHN---------------Y--GLAFDIALL-D----D-------NGE--V--DWTI-----DR--------RWK------------------------KAGEIG--KR----IG--L------EW----GGD-W------------------------------T-S-LK-----DYP----HFQYTFGLSLSELRSGKKP--------------------------------------------------------------------------------------------------------------------------------------------------- 119
 120 --------------DVHEIVQEKAYELIGQAY-K--ESI-FVSITEG-FRSIEHQHNLYSQG-R---TT---------------L--------------G-S-IVTNDKGG--YSYHN---------------Y--GLAIDIALL-D----N-------DGK--V--DWTI-----DR--------RWN------------------------KAGEIG--KR----IG--L------EW----GGD-W------------------------------T-S-LK-----DYP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 120
 121 ----------------------------ERCY-A--CGV-PILITQG-LRTAAEQDALYAQG-R---TK---------------S--------------G-A-IVTNARGG--QSYHN---------------Y--GLAVDFALL-L----P-------NGS--SV-SWDM-----ARDGDNDQAADWL------------------------EVVQQA--KR----LG--F------EW----GGD-W------------------------------T-S-LK-----DYP----HFQMS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 121
 122 ---------------------------------T--FGV-PIQITQG-LRTIAEQDALYAQG-R---TK---------------P--------------G-S-IVTNARGG--YSYHN---------------Y--GLAIDFALL-L----P-------NGS--SV-SWDM-----ARDGDKDRTTDWL------------------------EVVQQA--KR----LG--F------EW----GGD-W------------------------------T-S-LK-----DYP----HFQMS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 122
 123 ---------------LHPAVLAAATTLIERCY-A--CGV-PILITQG-LRTIAEQDALYAQG-R---TK---------------P--------------G-A-IVTNARGG--YSYHN---------------Y--GLAVDFALL-L----P-------NGS--SV-SWDM-----NRDGDSDCTADWL------------------------EVVQQA--KA----IG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HFQLS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 123
 124 ---------------LHPAVLTAATTLIERCY-A--CGV-PILITQG-LRTTAEQDALYAQG-R---TK---------------P--------------G-A-IVTNARGG--YSYHN---------------Y--GLAVDFALL-L----P-------NGS--SV-SWDM-----NRGGDNDCTADWL------------------------EVVQQA--KA----IG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HFQLS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 124
 125 ---------------LHPAVLAAATTLIERCY-A--CGV-SILITQG-LRTTAEQDALYAQG-R---TK---------------P--------------G-A-IVTNARGG--YSYHN---------------Y--GLAVDFALL-L----P-------NGS--SV-SWDM-----NRDGDNDCTADWL------------------------EVVQQA--KA----IG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HFQLS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 125
 126 ---------------LHPAVLAAATTLIERCY-A--CGV-PILITQG-LRTTAEQDALYAQG-R---TK---------------P--------------G-T-IVTNARGG--YSYHN---------------Y--GLAVDFALL-L----P-------NGS--SV-SWDT-----NKDGDNDCTADWL------------------------EVVQQA--KA----IG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HFQLS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 126
 127 --------------GLHPAVLAAATALIERSY-A--VGV-PILITQG-LRTIAEQDALYAQG-R---TR---------------P--------------G-A-IVTNARGG--YSYHN---------------Y--GLAADFALL-L----P-------DGS--SV-SWDM-----NRDENQNGTRDWL------------------------EVVQHA--KA----IG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HLQMS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 127
 128 --------------GLHPAVLAAATALIERSY-T--GGV-PILITQG-LRTMAEQDALYAQG-R---TR---------------P--------------G-A-IVTNARGG--YSYHN---------------Y--GLAADFALL-L----P-------DGS--SV-SWDM-----NRDGNQNGTQDWL------------------------EVVQRA--KA----IG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HLQMS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 128
 129 ---------------LHPVVKSAAEALIVRSY-A--CGV-PILITQG-LRTIAEQDALYAQG-R---TR---------------P--------------G-A-IVTNARGG--ESYHN---------------Y--GLAVDFALL-L----P-------NGS--SV-SWDM-----TRDVDQDGTPDWR------------------------EVVQQS--KA----IG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HLQMV----------------------------------------------------------------------------------------------------------------------------------------------------------------- 129
 130 ----------------HPVVMAAATVLIERCY-S--RGV-PILITQG-LRTIAEQNALYEQG-R---SK---------------P--------------G-A-IVTNARGG--YSYHN---------------F--GLAVDFALL-L----P-------NGS--SV-SWDM-----NRDYNGNNIKDWI------------------------EVVEEA--KK----LG--F------DW----GGD-W------------------------------T-S-FK-----DYP----HFQMV----------------------------------------------------------------------------------------------------------------------------------------------------------------- 130
 131 ------------------------TVLIERCY-A--RGV-PIVITQG-LRTIAEQDALYAQG-R---TK---------------P--------------G-S-IVTNAKGG--YSYHN---------------F--GLAVDFALL-L----P-------NGS--SV-SWDM-----NRDYNENNIKDWI------------------------EVVEEA--KK----LG--F------DW----GGD-W------------------------------T-S-FK-----DYP----HFQMV----------------------------------------------------------------------------------------------------------------------------------------------------------------- 131
 132 --------------NLHPVVRSAATALIERCY-K--LNI-PILITQG-LRTIDEQDALYAQG-R---TK---------------P--------------G-A-IVTNARGG--YSYHN---------------F--GLAVDFALL-L----P-------NGS--GV-SWDM-----CRDGNNNQIADWQ------------------------EVVKEA--KG----LG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HFQMA----------------------------------------------------------------------------------------------------------------------------------------------------------------- 132
 133 --------------NLHPVVRSAATALIERCY-K--LNI-PILITQG-FRTIAEQDALYAQG-R---TK---------------P--------------G-A-IVTNARGG--YSYHN---------------F--GLAVDFALL-L----P-------NGS--SV-SWDM-----CRDGNNNQIADWQ------------------------EVVKEA--KG----LG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HFQMA----------------------------------------------------------------------------------------------------------------------------------------------------------------- 133
 134 ---------------LHPVVRSAATALIERCY-K--LNI-PILITQG-LRTIAEQDALYAQG-R---TK---------------P--------------G-A-IVTNARGG--YSYHN---------------F--GLAVDFALL-L----P-------NGS--SV-SWDM-----RRDDNNNQIADWQ------------------------EVVKEA--KA----LG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HFQMA----------------------------------------------------------------------------------------------------------------------------------------------------------------- 134
 135 --------------NLHPVVRSAATALIERCY-K--LNI-PILITQG-LRTIAEQDALYAQG-R---TK---------------P--------------G-A-IVTNARGG--YSYHN---------------F--GLAVDFALL-L----P-------NGS--SV-SWDM-----RLDGNNNQIIDWQ------------------------EVVKEA--KA----LG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HFQMA----------------------------------------------------------------------------------------------------------------------------------------------------------------- 135
 136 --------------DLHPVVVAAAVALIERSY-A--RGV-QIIITQG-YRSKAEQDGLYAQG-R---TK---------------P--------------G-S-IVTNARGG--YSYHN---------------Y--GLAVDFALL-L----P-------DGY--SA-SWDM-----KRDGDKDGIADWQ------------------------EVAQQA--KA----LG--F------EW----GGD-W------------------------------M-S-FK-----DYP----HFQMS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 136
 137 ---------------LHPVVVAAAVALIERIY-A--RGV-QIIITQG-YRSKAEQDGLYAQG-R---TK---------------P--------------G-S-IVTNARGG--YSYHN---------------Y--GLAVDFALL-L----P-------DGS--GA-SWDM-----KRDGDKDGIADWQ------------------------EVVQQA--KA----LG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HFQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 137
 138 ---------------LHPVVSAAADKLIERCY-T--CGV-PVLITQG-LRTFSEQDRLYAQG-R---TS---------------A--------------G-N-IVTNARGG--YSFHN---------------Y--GLAVDFALL-L----P-------DGS--SA-SWDM-----KRDGDRDGTADWQ------------------------EVVQQA--KA----LG--F------EW----GGD-W------------------------------S-S-FK-----DYP----HFQMS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 138
 139 ---------------------------IERSY-A--RGV-NIVITQG-LRSIEEQDALYAQG-R---TK---------------P--------------G-A-IVTNAKGG--TSYHN---------------F--GLAVDFALL-L----P-------DGK--QV-SWDL-----KRDGDADGMRDWT------------------------EVVQGA--KA----LG--L------EW----GGD-F------------------------------V-S-IK-----DAP----HFQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 139
 140 ---------------------------IERCY-K--RGV-PIVITQG-LRTIEEQEALYAQG-R---TK---------------P--------------G-S-IVTNAKGG--TSYHN---------------Y--GLAVDFALL-L----P-------NGS--AV-SWDL-----KRDGDCDKATDWG------------------------EVVDEA--KE----LG--F------EW----GGD-F------------------------------T-S-IK-----DAP----HFQMS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 140
 141 -------------------------------Y-A--RGV-PIVITQG-LRTIAEQDSLYAKG-R---TK---------------P--------------G-Q-IVTNAKGG--HSYHN---------------Y--GLAIDFGLL-Q----L-------DGR--NV-SWDT-----TRDGDSDRVADWQ------------------------EVVQEA--KA----LG--F------EW----GGD-W------------------------------T-S-IK-----DYP----HFQMS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 141
 142 ---------------LQPVVKAAATALIERCY-A--RGV-NIVITQG-LRTIAEQDALYAQG-R---TK---------------P--------------G-Q-IVTNAKGG--HSYHN---------------Y--GLAIDFALL-L----P-------DGR--NV-SWDM-----NRDGDGDKVADWN------------------------EVVQEA--KA----LG--F------EW----GGD-W------------------------------T-S-IK-----DYP----HFQMS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 142
 143 ---------------LQPVVKAAATALIERCY-A--REV-NIVITQG-LRTIAEQDALYAQG-R---TK---------------P--------------G-Q-IVTNAKGG--TSYHN---------------Y--GLAIDFALL-L----P-------NGS--SV-SWDT-----TRDGDGDKVADWS------------------------EVVQEA--KA----LG--F------EW----GGD-W------------------------------T-N-FK-----DLP----HFQMV----------------------------------------------------------------------------------------------------------------------------------------------------------------- 143
 144 ---------------LHPVVLNAATLLIERCY-A--NGV-PILITQG-LRTIAEQDALYAQG-R---TK---------------P--------------G-V-VVTYAKGG--YSYHN---------------Y--GLAIDFALL-L----P-------SGT--AV-SWDM-----CRDGDGDRIADWQ------------------------EVVQQA--KA----LG--F------EW----GGD-W------------------------------S-S-FK-----DYP----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 144
 145 ---------------------------IQRCY-A--CGI-PILITQG-LRTLAEQEALYAQG-R---TK---------------P--------------G-T-VVTHARGG--YSYHN---------------Y--GLAVDFALL-L----P-------DGK--NV-SWDM-----LRDGNEDRIADWR------------------------QVVQTA--KI----LD--F------EW----GGD-W------------------------------S-G-FK-----DYP----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 145
 146 ----------------------GAKALIQQSY-A--RGV-PIVITQG-LRSIAEQNALYAQG-R---SK---------------P--------------G-P-IVTNAKGG--TSYHN---------------Y--GLAFDFALL-L----P-------DGN--SI-SWDM-----NRDGDKDKIADWQ------------------------EVVQVG--KQ----LG--L------EW----GGD-W------------------------------T-S-FK-----DYS----HLQMA----------------------------------------------------------------------------------------------------------------------------------------------------------------- 146
 147 ----------------------GAKALIQQSY-A--KGV-PIVITQG-LRSIAEQNALYAQG-R---NK---------------P--------------G-P-IVTNAKGG--TSYHN---------------Y--GLAFDFALL-L----P-------DGN--SL-SWDM-----NRDGDKDKIADWQ------------------------EVVQVG--KQ----LG--L------EW----GGD-W------------------------------T-S-FK-----DYS----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 147
 148 ------------------------NVLIQQSH-A--RGV-PIVITQG-LRTIAEQNALYAQG-R---SK---------------P--------------G-P-IVTNAKGG--TSYHN---------------Y--GLAFDFALL-L----P-------NGT--SL-SWDI-----NRDGDKDKTADWQ------------------------EVVQEA--KR----LG--L------EW----GGD-W------------------------------T-S-FK-----DYS----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 148
 149 ------------------------NVLIQQSH-A--RGV-PIVITQG-LRTIAEQNALYAQG-R---SK---------------P--------------G-P-IVTNAKGG--TSYHN---------------Y--GLAFDFALL-L----P-------NGT--SL-SWDI-----NRDGDKDKTADWQ------------------------EVVQEA--KR----LG--L------EW----GGD-W------------------------------T-S-FK-----DYS----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 149
 150 ---------------------------------F--KGV-PIIITQG-LRTIAEQNALYAQG-R---SK---------------P--------------G-P-IVTYARGG--TSYHN---------------Y--GLAVDFALL-Q----P-------DGK--TV-SWNM-----SRDLDQDRKADWQ------------------------EVVTVA--KQ----LG--F------EW----GGD-W------------------------------T-S-FK-----DNS----HLQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 150
 151 ----------------HPVLLAGATALIQRSY-A--KGI-PIVITQG-LRTIAEQNALYAQG-R---TK---------------P--------------G-S-IVTNARGG--TSYHN---------------Y--GLAIDFALL-L----P-------DGK--NV-SWDI-----SRDGNKDKIADWQ------------------------QVAQEA--KK----LG--F------AW----GGD-W------------------------------T-S-FK-----DYS----HLEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 151
 152 ---------------LHPVILAGASALIQRSY-A--KGI-PIVITQG-MRTIAEQNALYAQG-R---TK---------------P--------------G-N-IVTNARGG--TSYHN---------------Y--GLAIDFALL-L----P-------DGK--NV-SWDI-----SRDGNKDKIADWQ------------------------QVAQEA--KK----LG--F------AW----GGD-W------------------------------T-S-FK-----DYS----HLEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 152
 153 -----------------------------RSY-A--RGI-PILITQG-MRTIAEQNALYAQG-R---TK---------------K--------------G-A-IVTNARGG--SSYHN---------------Y--GLAIDFALL-L----P-------DGK--SV-SWDM-----KRDGDGDKVADWQ------------------------EVAQEA--KK----LG--F------EW----GGD-W------------------------------S-S-FK-----DYS----HLQMS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 153
 154 -----------------------------RSY-A--RGI-PILITQG-MRTIAEQNALYAQG-R---TK---------------K--------------G-A-IVTNARGG--SSYHN---------------Y--GLAIDFALL-L----P-------DGK--SV-SWDM-----KRDGDGDKVADWL------------------------EVAQEA--KK----LG--F------EW----GGD-W------------------------------S-S-FK-----DYS----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 154
 155 -----------------------------RSY-A--RGI-PILITQG-MRTIAEQNALYAQG-R---TK---------------K--------------G-A-IVTNAKGG--NSYHN---------------Y--GLAIDFALL-L----P-------DGK--SV-SWDM-----KRDGDGDKVADWQ------------------------EVAQEA--KK----LG--F------EW----GGD-W------------------------------S-S-FK-----DYS----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 155
 156 -----------------------------RSY-A--RGI-PILITQG-MRTIAEQNALYAQG-R---TK---------------K--------------G-A-IVTNAKGG--NSYHN---------------Y--GLAIDYALL-L----P-------DGK--SV-SWDM-----KRDGDGDKVADWQ------------------------EVAQEA--KK----LG--F------EW----GGD-W------------------------------S-S-FK-----DYS----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 156
 157 ---------------LHPVLQAAADELIQRSY-A--KGV-PIIITQG-MRTIAEQNALYAQG-R---TK---------------K--------------G-P-IVTNARGG--SSYHN---------------Y--GLAIDFALL-L----P-------DGN--NV-SWDM-----NRDGDSDKVPDWQ------------------------EVAEVA--KQ----LG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 157
 158 --------------KLHPAVLAGANELIRRSY-N--RGV-PILITQG-MRTIAQQNELYAQG-R---TK---------------K--------------G-D-IVTNARGG--DSYHN---------------Y--GLAIDFALL-L----P-------DGR--NV-SWDM-----KRDGDGDKVADWQ------------------------EVVQEG--KK----LG--F------EW----GGD-W------------------------------T-S-FK-----DYA----HLQMS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 158
 159 --------------KLHPAVLAGANELIRRSY-N--RGV-PILITQG-MRTIAQQNELYAQG-R---TK---------------K--------------G-D-IVTNARGG--DSYHN---------------Y--GLAIDFALL-L----P-------DGR--NV-SWDM-----NRDGDGDKVADWQ------------------------EVAQEG--KQ----LG--F------EW----GGD-W------------------------------T-S-FK-----DYA----HLQMS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 159
 160 ----------------HPVLLAAAHVLIQRCY-A--RGI-PIIITQG-LRTIAEQNALYAQG-R---TR---------------K--------------G-P-IVTNARGG--SSFHN---------------Y--GLAMDFALL-L----P-------DGQ--NI-SWDM-----SRDGDGDKLADWQ------------------------EVVQEA--KK----LG--L------EW----GGD-W------------------------------T-S-FK-----DYS----HLQMA----------------------------------------------------------------------------------------------------------------------------------------------------------------- 160
 161 ------------------ALLAAANVLIQRCY-V--RGI-PIVITQG-LRTIAEQNALYALG-R---TK---------------K--------------G-A-IVTNARGG--SSFHN---------------Y--GLAIDFALL-L----P-------DGR--NI-SWDM-----SRDGDGDKLADWQ------------------------EVVQEA--KK----LG--L------EW----GGD-W------------------------------T-S-FK-----DYS----HFQMA----------------------------------------------------------------------------------------------------------------------------------------------------------------- 161
 162 ---------------LQPVIKDAATALIEFAY-A--HGV-PIMITQG-LRTIAEQDSLYAQG-R---TK---------------P--------------G-Q-IVTNAKGG--YSYHN---------------F--GVAIDFALL-L----P-------DG---SV-SWDT-----KRDGDGDGVADWS------------------------EVVADA--KR----LG--W------EW----GGD-W------------------------------T-S-FK-----DLP----HFQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 162
 163 --------------GLQPVVRQVAEALIEFAY-A--HGV-PIVITQG-LRTIPEQDGLYAQG-R---TK---------------P--------------G-Q-IVTNAKGG--YSYHN---------------F--GVAIDFALL-L----P-------GG---GV-SWDM-----KRDGDGDGIADWQ------------------------EVVDAA--KR----LG--W------EW----GGD-W------------------------------T-S-FK-----DYP----HFQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 163
 164 ---------------------------------A--CGV-PIVITQG-LRTIDEQNALYAQG-R---TT---------------R--------------G-Q-IVTNARGG--YSYHN---------------F--GVAIDFALL-L----P-------DG---GV-SWDT-----KRDGDCDGLADWG------------------------EVVAQA--KR----LG--W------DW----GGD-W------------------------------R-S-FT-----DLP----HFEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 164
 165 ---------------------------IERCY-N--RGV-PIVITQG-LRTYAEQDALYTQG-R---TK---------------P--------------G-A-IVTNARGG--YSNHN---------------F--GVAIDFALL-L----P-------DGR--TC-SWDT-----KRDGDRDGVADWN------------------------EVVAEA--KR----LG--F------EW----GGD-W------------------------------R-T-FT-----DLP----HFEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 165
 166 -------KSAARLIGLHPVVQQATVRLIELAY-Q--AGV-PIVITQG-LRTFAEQDALYAQG-R---TK---------------P--------------G-Q-IVTNARGG--YSNHN---------------F--GVAIDFALL-M----P-------DGR--SV-TWDM-----TRDGDGDKRADWA------------------------EVADIA--KR----LG--F------SW----GGD-W------------------------------T-S-FK-----DYP----HFDMTFGLSTADFRAGKQPSQAAQAAALAIINKEGEDRMNAQDKAAIEALQAAVAKQEK----------------------------------------------------------------------------------------------------------- 166
 167 --EFILSKSSKRLSDLHPTVKVAAEKLIINSY-K--RGV-PIVITQG-LRTFAEQNALYAQG-RYGDKR---------------P------------------IVTNAKAG--ESFHN---------------Y--GVAIDFALL-L----P-------DGK--NV-SWDM-----QRDGDGDRQCDWL------------------------EVVEEA--KK----LG--F------QW----GGD-W------------------------------I-N-FK-----DSP----HFEMTFGLSIKDFQLGKRPPVVNESIKEVEDNMPLQLNDY------------------------------------------------------------------------------------------------------------------------------ 167
 168 -------------------VKAAAEALIDRSF-A--LGI-PIVVTQG-LRTFAEQNALYEQG-R---TK---------------P--------------G-S-IVTNARGG--YSNHN---------------F--GVAIDFALL-T----N-------DGR--AV-SWDT-----KLDGNRNGKADWN------------------------EVVTLA--KA----LG--F------TW----GGD-W------------------------------K-T-FL-----DLP----HFEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 168
 169 ------------------CVKAAAEALIDRSY-A--AGI-PIIIVQG-LRTIAEQDALYAQG-R---SK---------------P--------------G-Q-IVTNAKGG--YSNHN---------------F--GVAIDFALL-T----N-------DGR--SV-SWDT-----KLDGNRNGKADWN------------------------EVVAIA--KA----LG--F------TW----GGD-W------------------------------K-T-FV-----DLP----HFEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 169
 170 ------SKSATRLQGLLPVVRTAAECLIERSF-A--LGI-PIVITQG-LRTIAEQNELYAQG-R---TK---------------P--------------G-P-KVTNAKGG--TSYHN---------------F--GVAIDFSLL-L----P-------DGR--SV-SWDT-----QRDGNADHKADWM------------------------QVVAIA--KE----LG--F------EW----GGD-W------------------------------K-T-FT-----DLP----HLQIVFGLSTAQYRAGKRPTKAQIDSVLSRINKTGDDEPMTLEE-------------------------------------------------------------------------------------------------------------------------- 170
 171 -------------------------------Y-N--RGV-QIIITQG-LRTYAEQDNLYAKG-R---TA---------------KQLAAVGLSKVTPQPK-EDIVTNARGG--YSNHN---------------F--GWANDFALL-L----P-------DGR--TV-SWDT-----LRDDDKDSLPDWS------------------------EVVEEA--KK----LG--F------AW----GGD-W------------------------------R-T-FK-----DMP----HLEMV----------------------------------------------------------------------------------------------------------------------------------------------------------------- 171
 172 ------------------PLRTGCAALIELAY-N--RGV-MPIITQG-MRTYAEQDALYAQG-R---TK---------------P--------------G-A-IVTNARGG--YSNHN---------------F--GFAADFALL-L----P-------DGR--TV-SWDT-----LRDDDKDSLPDWS------------------------EVVDQI--RR----LG--F------DW----GGD-W------------------------------L-S-FK-----DMP----HFEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 172
 173 -------------------IRQAAECLIDRCY-D--RDV-WIIITQG-LRTYAEQDALFAQG-R---TK---------------S--------------G-Q-VVTKARGG--YSIHN---------------F--GYAIDFALL-L----R-------DGR--TV-SWET-----LRDDDKDSLPDWS------------------------EVVEEA--KR----LG--F------EW----GGD-W------------------------------R-S-FK-----DMP----HIQMIFGLSTADFRAGKRPTQAQLNAVLAKINSL------------------------------------------------------------------------------------------------------------------------------------ 173
 174 -------------------IRQATECLIDRCY-D--RAV-WIIITQG-LRTYAEQDALYAQG-R---TK---------------S--------------G-Q-VVTKARGG--YSIHN---------------F--GYAIDFALL-L----R-------DGR--TV-SWDT-----LRDDDKDSLPDWS------------------------EVVEEA--KR----LG--F------EW----GGD-W------------------------------R-S-FK-----DMP----HLQMVFGLSTADFRAGKRPTQAQLDAVLAKINSL------------------------------------------------------------------------------------------------------------------------------------ 174
 175 --------------------KIVVEKLIERCY-A--RGV-RIVITQG-LRTYAEQDALYAQG-R---NG---------------D--------------K-RPKVTKARGG--YSNHN---------------F--GFAADFALL-L----R-------DGR--TV-SWDT-----LRDDDKDSLPDWS------------------------EVVEEA--KR----LG--L------EW----GGN-W------------------------------R-S-FK-----DMP----HLQMTFGLSTADFRAGKRPTQSQLNTILAKINSLKMED-------------------------------------------------------------------------------------------------------------------------------- 175
 176 ---------------LHPVVKGKATQLIENAY-N--RGV-QILITDG-YRSFAEQQRLYNQG-R---TT---------------P--------------G-S-IVTNARPG--QSYHN---------------Y--GLAID---F-A----L----YTKDGR--KV-VWDT-----RIDGDGDGLSDWD------------------------EVVIEA--KK----LG--F------KW----GGD-W------------------------------V-S-FR-----DFP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 176
 177 ------------PSGLHPIVEEKRDLLVTRAAE---IGI-DILITDG-YRSPEEQEGLHNQG-R---NM---------------P--------------G-A-IVTYAAAG--ESYHN---------------Y--GLAIDYALR-L----D-------DDS----VVWDI-----ERDDNGNGKSDWF------------------------EVAAIG--KQ----LG--F------DW----GGD-W------------------------------Q-R-FK-----DYP----HLEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 177
 178 -------------------------------------GI-DILITDG-YRSPEEQQGLHNQG-R---NM---------------P--------------G-A-IVTYAAAG--ESYHN---------------Y--GLAIDYALR-L----D-------DDS----VVWDI-----ERDDNDNGKSDWF------------------------EVAAIG--KQ----LG--F------DW----GGD-W------------------------------Q-R-FK-----DYP----HLEMTF---------------------------------------------------------------------------------------------------------------------------------------------------------------- 178
 179 --------------GLYPIVEENRDFLVAKAAE---LGI-DLIITDG-YRSPEEQQGLHNQG-R---NM---------------P--------------G-A-IVTYAAAG--ESYHN---------------Y--GLAIDYALR-L----D-------DGS----VVWDI-----ERDDNGNGKSDWF------------------------EVAAIG--KS----LG--F------DW----GGD-W------------------------------Q-R-FK-----DYP----HLEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 179
 180 -------------------------------------GI-DILITDG-YRSPEEQDRLHNQG-R---SA---------------P--------------G-T-VVTYAEAG--ESYHN---------------Y--GLAIDYALR-L----D-------DGS----VVWDI-----TRDDNDNGESDWF------------------------EVAAIG--KK----LG--F------DW----GGD-W------------------------------Q-R-FK-----DYP----HLEMTF---------------------------------------------------------------------------------------------------------------------------------------------------------------- 180
 181 -------------------------QLVQQAQS---IGI-DILITDG-FRSAEEQNDLHNQG-R---SA---------------A--------------G-N-IVTYARGG--ESYHN---------------Y--GLAIDFALR-L----D-------NGD----VVWDI-----ERDDNGNGERDWY------------------------EVAAIG--KE----LG--F------AW----GGD-W------------------------------Q-R-FK-----DYP----HLEMTFGLSIGELQQG------------------------------------------------------------------------------------------------------------------------------------------------------ 181
 182 -------------SGLHPIVEEKSEELVSKAAA---IGI-QVLITDG-FRSADEQNGLHAKG-R---ST---------------T--------------G-N-VVTYARGG--DSYHN---------------Y--GLAIDFALK-L----S-------NGE----VVWDT-----ARDDNKNGKADWF------------------------EVAAIG--KE----LG--F------QW----GGD-W------------------------------Q-R-FK-----DYP----HLEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 182
 183 -------------------------QLIGKAEE---IGI-PILISDS-FRSVESQDVLYEKG-R---SI---------------E--------------G-D-IVTYARGG--ESYHN---------------Y--GLAIDFVLQ-N----S-------DGT----ISYDL-----QRDLNGNGEADWY------------------------EVASIG--KD----LG--F------EW----GGD-W------------------------------P-S-FK-----DYP----HLEYTF---------------------------------------------------------------------------------------------------------------------------------------------------------------- 183
 184 -------------------------------------GI-TVVITEG-FRSIEEQNELYRQG-R---SK---------------K--------------G-N-IVTYAKGG--ESYHN---------------Y--GLAIDFALQ-K----K-------DGS----LIWDM-----TYDGNRNGTPDWL------------------------EVVSIA--KT----LG--F------DW----GGD-W------------------------------R-G-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 184
 185 -------------------------------------GI-TVVITEG-FRSIEEQNELYRQG-R---SK---------------K--------------G-N-IITYAKGG--ESYHN---------------Y--GLAIDFALQ-K----K-------DGS----LIWDM-----TYDGNRNGTPDWL------------------------EVVSIA--KT----LG--F------DW----GGD-W------------------------------R-G-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 185
 186 -----------IPSALHPLVKQNAELLQTAALK---KGI-TVVITEG-FRSIEEQNELYRQG-R---SK---------------K--------------G-N-IVTYAKGG--ESYHN---------------Y--GLAIDFALQ-K----K-------DGS----LIWDM-----TYDGNRNGTPDWL------------------------EVVSIA--KK----LG--F------DW----GGD-W------------------------------R-G-FK-----DYP----HLQMIPG--------------------------------------------------------------------------------------------------------------------------------------------------------------- 186
 187 -----------IPSALHPLVKQNAELLQTAALK---KGI-TVVITEG-FRSIEEQNELYRQG-R---SK---------------K--------------G-N-IVTYAKGG--ESYHN---------------Y--GLAIDFALQ-K----K-------DGS----LIWDM-----TYDGNRNGTPDWL------------------------EVVSIA--KK----LG--F------DW----GGD-W------------------------------R-G-FK-----DYP----HLQMIP---------------------------------------------------------------------------------------------------------------------------------------------------------------- 187
 188 -----------IPNALHPLVKQNAELLQTAALK---KGI-TVVITEG-FRSIEEQNELYRQG-R---SK---------------K--------------G-N-IVTYAKGG--ESYHN---------------Y--GLAIDFALQ-K----K-------DGS----LIWDM-----TYDGNQNGRPDWL------------------------EVVSIA--KT----LG--F------DW----GGD-W------------------------------R-N-FK-----DYP----HLQMIPG--------------------------------------------------------------------------------------------------------------------------------------------------------------- 188
 189 ------------------------------AEK---KGI-SIVITEG-FRSIEEQNELYKQG-R---SK---------------K--------------G-N-IVTYAKGG--ESYHN---------------Y--GLAIDFALQ-Q----K-------NGS----LLWDI-----EYDGNQNGTSDWL------------------------EVVAIA--KK----LG--F------EW----GGD-W------------------------------K-R-FK-----DYP----HLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 189
 190 ------------------------------AEK---KGI-SIVITEG-FRSIEEQNELYKQG-R---SK---------------K--------------G-N-IVTYAKGG--ESYHN---------------Y--GLAIDFALQ-Q----K-------NGS----LLWDI-----EYDGNQNGTSDWL------------------------EVVAIA--KK----LG--F------EW----GGD-W------------------------------K-R-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 190
 191 -----------VPSDLHPIVKQNADALKAAAAN---KGI-TVVITEG-FRSFKEQDELYKQG-R---TK---------------K--------------G-N-IVTYARGG--ESYHN---------------Y--GLAIDFALQ-K----K-------DGS----IIWDM-----EYDGNQNGKSDWL------------------------EVVEIA--KT----LG--F------EW----GGD-W------------------------------K-R-FK-----DYP----HLEMIPN--------------------------------------------------------------------------------------------------------------------------------------------------------------- 191
 192 -----------VPSDLHPIVKQNADALKAAAAN---KGI-DVVITEG-FRSFKEQDELYKQG-R---TK---------------K--------------G-N-IVTYARGG--ESYHN---------------Y--GLAIDFALQ-K----K-------DGS----IIWDM-----EYDGNQNGKSDWL------------------------EVVEIA--KT----LG--F------EW----GGD-W------------------------------K-R-FK-----DYP----HLEMIPN--------------------------------------------------------------------------------------------------------------------------------------------------------------- 192
 193 -----------VPSDLHPIVKQNADALKAAAAN---KGI-NVVITEG-FRSFKEQDELYKQG-R---TK---------------K--------------G-N-IVTYARGG--ESYHN---------------Y--GLAIDFALQ-K----K-------DGS----IIWDM-----EYDGNQNEKSDWL------------------------EVVEIA--KT----LG--F------EW----GGD-W------------------------------K-R-FK-----DYP----HLEMIPN--------------------------------------------------------------------------------------------------------------------------------------------------------------- 193
 194 -------------------------------------GI-TVVITEG-FRSFKEQDELYKQG-R---TK---------------K--------------G-N-IVTYARGG--ESYHN---------------Y--GLAIDFALQ-K----K-------DGS----IIWDM-----EYDGNQNGKSDWL------------------------EVVEIA--KQ----LG--F------EW----GGD-W------------------------------K-R-FK-----DYP----HLEM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 194
 195 -----------VPSDLHPVVQQNADALKAAAAN---KSI-TVIITEG-FRSFKEQDELYKQG-R---TK---------------K--------------G-N-IVTYAKGG--ESYHN---------------Y--GLAIDFALQ-K----K-------DGS----IIWDM-----EYDGNQNGKSDWL------------------------EVVEIA--KK----LG--F------EW----GGD-W------------------------------K-R-FK-----DYP----HLEMIPD--------------------------------------------------------------------------------------------------------------------------------------------------------------- 195
 196 -------------------------------------GI-HIVITEG-FRSFEEQDELYKQG-R---TK---------------K--------------G-N-IVTYARGG--ESYHN---------------Y--GLAIDFALR-K----K-------DGS----IIWDI-----EYDGNQNGQSDWL------------------------EVVEIA--KK----LG--F------EW----GGD-W------------------------------K-R-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 196
 197 -------------------VKQNADTLKAAASN---KGI-SIVITEG-FRSFKEQDELYKQG-R---TK---------------K--------------G-N-IVTYAKGG--ESYHN---------------Y--GLAIDFALQ-K----K-------DGS----ILWDM-----DYDGNQNGISDWL------------------------EVVTIA--KK----LG--F------EW----GGD-W------------------------------E-R-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 197
 198 ---------------------AGKNKLISQAKA---KGI-SLLVTDG-FRSSAKQNQLYAKG-R---SE---------------K--------------G-N-IVTTARGG--ESYHN---------------Y--GLAIDFALR-K----K-------DGS----VVWDM-----RMDENKNGLSDWM------------------------EVVKLA--KR----LG--F------SW----GGD-W------------------------------E---FK-----DYP----HLQMEF---------------------------------------------------------------------------------------------------------------------------------------------------------------- 198
 199 ---------------LHPLVAEKKDELIALAAG---KGI-NVVITQD-FRSIEEQNALYEKG-R---TA---------------E--------------G-N-IVTHAKGG--ESYHN---------------F--GLAIDFALM-S----V-------DGQ----VIWDM-----KYDGNGNSRADWD------------------------EVVEIA--KD----LG--F------EW----GGD-W------------------------------T-Q-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 199
 200 YIGPPNLEDTSLPTALHPAVAEKKDQLISQAAD---KGI-NVVITQD-FRSIEEQDALYEKG-R---TA---------------E--------------G-S-IVTHAKGG--ESYHN---------------F--GLAIDFALM-S----V-------DGQ----VIWDM-----NYDSNGNSKADWD------------------------EVVEIA--KD----LG--F------EW----GGD-W------------------------------T-Q-FK-----DYP----HLQMDF---------------------------------------------------------------------------------------------------------------------------------------------------------------- 200
 201 ---------------LHPVVSAKKDELISLAAD---KGI-NIVITQD-FRSIEEQNELYAKG-R---TA---------------E--------------G-E-IVTNAKGG--ESYHN---------------F--GLAIDFALL-S----L-------NGA----VIWDM-----NYDGNGNSRADWD------------------------EVVEIA--KG----LG--F------EW----GGD-W------------------------------R-S-FK-----DYP----HLQYDFGLSIWELQRGKRPP-------------------------------------------------------------------------------------------------------------------------------------------------- 201
 202 -----------LPVQLHPVVSAKKDELISLAAD---KGI-NIVITQD-FRSIEEQNELYAKG-R---TA---------------E--------------G-E-IVTNAKGG--ESYHN---------------F--GLAIDFALL-S----L-------NGA----VIWDM-----NYDGNGNSRADWD------------------------EVVEIA--KG----LG--F------EW----GGD-W------------------------------R-S-FK-----DYP----HLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 202
 203 --------------GLNPVVEENKDILVKKAGD---IGI-RVVITED-FRSVEEQDRLYEQG-R---TR---------------E--------------G-S-VVTNAKGG--ESYHN---------------Y--GLAIDFALL-D----I-------NGA----VIWDM-----KYDGNGNGKTDWS------------------------EVVEIA--KE----LG--F------QW----GGD-W------------------------------T-N-FK-----DYP----HFQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 203
 204 -TSIEQKKDVPLPTELHPIVKERSDQLVQQAAK---IGI-VVMITDG-FRSIEEQNTIYEQG-R---TA---------------E--------------G-N-IVTNAKGG--ESYHN---------------Y--GLAIDFALE-T----T-------SGD----VIWDR-----QYDRNQNGKSDWS------------------------EVVKIA--KS----LG--F------EW----GGD-W------------------------------K-G-FK-----DYP----HFQMDFGLTIADLQNGERPEDTSNVADT------------------------------------------------------------------------------------------------------------------------------------------ 204
 205 --------------------------------------------------------LLYEQG-R---TT---------------E--------------G-N-IVTNAKGG--ESYHN---------------F--GLAVDFAIK-L----P-------SGE----VIWDR-----QYDGNGNSVADWT------------------------EVVAIA--KK----LG--F------DW----GGD-W------------------------------K-S-FK-----DYP----HLQMDFGLAIADLQRGA----------------------------------------------------------------------------------------------------------------------------------------------------- 205
 206 -------HSNSLPTELHPIVKERTNQLVQQAAD---KGI-VIVITDG-FRSADDQNRLYEKG-R---SA---------------E--------------G-S-IVTYAKGG--ESYHN---------------F--GLAIDFALK-T----P-------SGN----VIWDM-----DYDGNKNGKADWN------------------------EVVSLA--KT----LG--F------EW----GGD-W------------------------------A-K-FK-----DYP----HLQMDFGLTIAQLQNGERPAESS----------------------------------------------------------------------------------------------------------------------------------------------- 206
 207 --------------------KERSNQLIQQSAK---KGI-VIVITDG-FRSAEDQNRLYEKG-R---TA---------------D--------------G-T-IVTYAKGG--ESYHN---------------F--GLAIDFALK-T----P-------SGD----VIWDR-----QYDGNKNGKADWA------------------------EVVEMA--KV----LG--F------QW----GGD-W------------------------------T-Q-FK-----DYP----HLEMNFGLTIAELQNGDRPAGSSMTADTTKD--------------------------------------------------------------------------------------------------------------------------------------- 207
 208 ------------PQELHPVVQENKDVLVQKAAE---IGI-RVLVTDG-FRSFEEQNQLYEKG-R---SK---------------D--------------G-Q-IVTHAKGG--ESYHN---------------F--GLAIDFALL-N----K-------QGK----ALWDT-----TYDGNGNGKSDWM------------------------EVVGIA--KE----LG--F------TW----GGD-W------------------------------N-H-FK-----DYP----HLEMR----------------------------------------------------------------------------------------------------------------------------------------------------------------- 208
 209 --------------------------LVQKAAE---RGI-KVLVTDG-FRSFEEQNQLYEKG-R---SR---------------E--------------G-Q-IVTHAKGG--ESYHN---------------F--GLAIDFALV-N----K-------SGK----ALWDT-----NYDGNGNGKSDWM------------------------EVVGIA--KE----LG--F------MW----GGD-W------------------------------K-H-FK-----DYP----HIEMRFGLTINDLKRGKRPPQDALTAS------------------------------------------------------------------------------------------------------------------------------------------- 209
 210 --------------------------LVKTAAD---SGI-SIIVTDG-FRSFQEQDFLYQKG-R---TT---------------D--------------G-Q-IVTHAKAG--DSYHN---------------F--GLAIDFALL-D----K-------QGK----ALWDT-----AYDGNGNGKSDWM------------------------EVVAIA--KE----LG--F------QW----GGD-W------------------------------E-H-FK-----DYP----HFEMRFGLTIDDLQRGKRPPQNS----------------------------------------------------------------------------------------------------------------------------------------------- 210
 211 -------------DELNPIVAEKKDELIQLAKD---KGI-PVIITAG-FRSLAEQNELYEKG-R---SD---------------P--------------G-N-IVTNARGG--ESLHN---------------F--GLAIDFALL-N----K-------QGE----AIWDM-----SYDGNDNGKSDWM------------------------EVVTIA--KG----LG--F------DW----GGD-W------------------------------A-G-FK-----DYP----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 211
 212 --------------------DRKKDELISLAAA---KGI-KVVITDG-FRSSAEQDVLYSKG-R---EG---------------G--------------G-S-IVTHARGG--ESYHN---------------Y--GLAIDFALK-D----R-------TGD----IIWDM-----EYDGNKNGKADWL------------------------EVVAIA--KS----LG--F------TW----GGD-W------------------------------P-Q-FP-----DNP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 212
 213 --------------------DRKKDELISLAAA---KGI-KVVITDG-FRSSAEQDVLYSKG-R---EG---------------G--------------G-S-IVTHARGG--ESYHN---------------Y--GLAIDFALK-D----R-------TGD----IIWDM-----EYDGNKNGKADWL------------------------EVVAIA--KS----LG--F------TW----GGD-W------------------------------P-Q-FP-----DNP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 213
 214 -------------------------ELLAKTAA---IGI-QVVITDD-FRSMEEQDKLYSQG-R---TS---------------E--------------G-K-IVTHAKAG--ESYHN---------------Y--GLAIDFALK-T----K-------SGK----IIWDM-----NADLNGDGRKDWS------------------------QVVAIA--KE----LG--F------EW----GGD-W------------------------------T-N-FP-----DYP----HLQLSYGLSIAELQRGTKTARS------------------------------------------------------------------------------------------------------------------------------------------------ 214
 215 -------KDFSGATELHPVVEEKKNKLVQQAND---QGI-SIVITEG-FRSKEEQDKLYAKG-R---TE---------------E--------------G-N-IVTYSKGG--QSYHN---------------Y--GLAIDFAIR-L----K-------DGR----VVWDM-----EYDGNHNNQSDWM------------------------EVVDIA--KG----LE--F------EW----GGD-W------------------------------Q-G-FK-----DYP----HFQMN----------------------------------------------------------------------------------------------------------------------------------------------------------------- 215
 216 -------------TDLHPVVEEKKNKLVQQASD---QGI-SIVITEG-FRSKEEQDKLYAKG-R---TE---------------E--------------G-N-IVTYSKGG--QSYHN---------------Y--GLAIDFAIQ-L----K-------DGR----VIWDM-----EYDGNNNNQSDWM------------------------EVVDIA--KN----LG--F------EW----GGD-W------------------------------Q-G-FK-----DYP----HFQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 216
 217 ---------------LHPTVEKNMNELIEKTSD---IGI-SIIITDD-YRSKEEQDKLYAQG-R---TT---------------E--------------G-Q-IVTQVQGG--ESMHN---------------Y--GLAIDFALE-P----E-------PGN----VIWDM-----EYDGNKNGESDWM------------------------EVVDIA--KE----LG--F------EW----GGD-W------------------------------P-G-FK-----DYP----HLEMH----------------------------------------------------------------------------------------------------------------------------------------------------------------- 217
 218 ------------PQGLHPIVQKKSDELVERASE---QDI-QIIITDG-FRSFEEQDEIYAQG-R---TR---------------E--------------G-S-IVSYAQGG--ESYHN---------------Y--GLAIDFALQ-T----E-------DD-----VIWDL-----EYDGNGNGESDWM------------------------EVVEIA--KD----LG--F------AW----GGD-F------------------------------R-G-FK-----DYP----HFEMR----------------------------------------------------------------------------------------------------------------------------------------------------------------- 218
 219 ------------PTGLHPIVEEKQDDLVQRASE---EGI-NIVITDG-FRSFEEQDEIYAQG-R---TR---------------E--------------G-N-IVSYAEGG--ESYHN---------------Y--GLAIDFVLQ-T----D-------DD-----VIWDL-----EYDGNGNGESDWM------------------------EVVEIA--KD----LG--F------TW----GGD-F------------------------------R-G-FK-----DYP----HFEMR----------------------------------------------------------------------------------------------------------------------------------------------------------------- 219
 220 ------LANVPMPTELHPVVEEKKNELIEQSAE---QGI-EIVITDG-FRSAEEQDKIYEQG-R---SE---------------E--------------G-N-IVTNARGG--ESYHN---------------F--GLAIDFAIR-T----N-------EDT----VVWDM-----EYDGNNNERSDWM------------------------EVVEIA--KE----LG--F------SW----GGD-W------------------------------H-G-FK-----DYP----HFEMRFGLSIRELQRG------------------------------------------------------------------------------------------------------------------------------------------------------ 220
 221 ------------PKSLHPAVQKAKERLIDLTKE---KGI-NIVITDG-HRSKEEQNALYEKG-R---SK---------------S--------------G-D-IVTHVKGG--GSYHN---------------Y--GLAIDFALK-L----D-------NGN----VIWDM-----KHDGNGNGESDWM------------------------EVVAIA--KD----LG--F------EW----GGD-W------------------------------S-S-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 221
 222 -------------------------ELVASAKE---KGI-SVVITDG-FRSKEQQNALYQQG-R---SD---------------S--------------G-L-VVTQVQGG--YSYHN---------------Y--GLAIDFALR-T----K-------SGD----VIWDL-----EFDGNRNGQADWM------------------------EVVAVA--KQ----LG--F------SW----GGD-W------------------------------EGS-FK-----DYP----HLQMDFGYSIQALKSGKRPPVESQP--------------------------------------------------------------------------------------------------------------------------------------------- 222
 223 -----------IPTELHPKVEEAKQTLIQRAEA---KDI-TIVITDG-HRTEAEQDELYQQG-R---SE---------------P--------------G-N-IVTYASGG--ESYHN---------------Y--GLAIDFALR-V----D-------NGE----VVWDM-----QRDGNGNGESDWM------------------------EVVAIA--KD----LG--F------EW----GGD-W------------------------------T-S-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 223
 224 ------------PTKLHPKVESAKEKLKQLAQE---KGI-DIVITDG-IRSKKEQNELYAQG-R---SD---------------K--------------G-D-IVTHARGG--ESYHN---------------Y--GLAIDYALK-L----D-------NGE----VVWDI-----ERDGNGNGKADWM------------------------EVAHIA--KD----LG--F------EW----GGD-W------------------------------P-S-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 224
 225 ------------PTELHPKVEKAKHTLLKRAEE---KGI-SVVITDG-HRSIERQNELYAQG-R---ED---------------K--------------G-S-VVTHADGG--ESYHN---------------Y--GLAIDFALK-T----N-------SGD----VVWDT-----TRDGNGNGKADWM------------------------EVVSIA--KD----LG--F------EW----GGD-W------------------------------S-S-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 225
 226 ------------------------EELVARAAE---QGI-EMVITDG-HRSVESQNELYARG-R---SE---------------E--------------G-K-VVTHAKGG--ESYHN---------------Y--GLAIDFALQ-T----D-------NG-----VVWNM-----ERDGNGNGKSDWM------------------------EVVAIA--KD----LG--F------EW----GGD-W------------------------------S-N-FK-----DYP----HLQMDF---------------------------------------------------------------------------------------------------------------------------------------------------------------- 226
 227 --------------MLHPKVEEYKNNLIASSKE---RGI-DIVITEG-HRSMERQNELYDRG-R---ST---------------D--------------G-D-IVTYAEGG--ESYHN---------------Y--GLAIDFALR-L----E-------NGN----VVWDM-----NRDGNGNGEADWL------------------------EVVSLA--KD----MG--F------EW----GGD-F------------------------------S-N-FK-----DYP----HFQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 227
 228 ------------PDNLHPTVKERKDELVERVRE---KGI-QIVITEG-HRSEEKQDALYAQG-R---SS---------------E--------------G-E-VVTHAKGG--ESYHN---------------Y--GLAIDFALK-A----E-------GGN----VIWDR-----EYDGNGNGQSDWM------------------------ETVEVA--KE----LG--F------EW----GGD-W------------------------------E-N-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 228
 229 -----------VPTDLHPVVEQKKEELMDAVRA---KGI-DVVITEG-HRTMERQDALYAQG-R---SE---------------G--------------G-S-IVTSAKGG--ESYHN---------------Y--GLAIDFALR-T----A-------EGD----VVWDR-----VRDDNGNGEPDWM------------------------EVVEEA--KS----LG--F------EW----GGD-W------------------------------S-N-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 229
 230 --------------ELHPYVLKQKNELVRLTEE---KGI-TIIISDG-YRSHEEQTRIYNQG-R---TT---------------G--------------G-S-IVTNAKAG--ESLHN---------------Y--GLAIDFALK-L----K-------DGS----VIWDM-----EYDGNNNGKSDWM------------------------EVVEIA--KS----LG--F------QW----GGD-W------------------------------A-N-FP-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 230
 231 ----FNSKETPEITQLHPYVLQQKNELVRLTKK---KGI-TIVITDG-YRSHEEQTRIYNQG-R---ST---------------E--------------G-N-IVTNAKAG--ESLHN---------------Y--GLAIDFALR-L----K-------DGS----VIWDM-----EYDGNGNGKADWM------------------------EVVEIA--KD----LG--F------QW----GGD-W------------------------------A-N-FP-----DYP----HLQIDF---------------------------------------------------------------------------------------------------------------------------------------------------------------- 231
 232 -------------TQLHPYVLQQKNELVRLTKK---KGI-TIVITDG-YRSHEEQTRIYNQG-R---ST---------------E--------------G-N-IVTNAKAG--ESLHN---------------Y--GLAIDFALR-L----K-------DGS----VIWDM-----EYDGNGNGKADWM------------------------EVVEIA--KD----LG--F------QW----GGD-W------------------------------A-N-FP-----DYP----HLQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 232
 233 -------------------------ELVRLTKQ---RGI-TIVITDG-YRSHEEQTRIYNQG-R---TT---------------E--------------G-D-IVTNAKAG--QSLHN---------------Y--GLAIDFALR-L----E-------DGS----VIWDM-----EYDGNGNGKSDWM------------------------EVVAIA--KE----LG--F------EW----GGD-W------------------------------D-K-FP-----DYP----HLQMDF---------------------------------------------------------------------------------------------------------------------------------------------------------------- 233
 234 -------------------VAENEKLLVRKAAR---RGI-AIVITHG-YRSSEEQDALFNQG-R---SS---------------A--------------G-N-IVTNARGG--ESYHN---------------Y--GLAIDFALR-T----P-------EGD----VVWDM-----ERDDNGNGKADWM------------------------EVVDLA--KE----LG--F------TW----GGD-W------------------------------A-N-FP-----DYP----HLQMDFGLSINELKRGKRPPDS------------------------------------------------------------------------------------------------------------------------------------------------ 234
 235 -------------------VAESEKLLVRKAAR---RGI-EIVITHG-FRSNEEQDALFNQG-R---SI---------------A--------------G-N-IVTNAQGG--ESYHN---------------Y--GLAIDFALR-T----P-------EGD----VVWDM-----ERDDNGNGQADWL------------------------EVVELA--KE----LG--F------TW----GGD-W------------------------------A-N-FP-----DYP----HLQMDFGLSINDLKRG------------------------------------------------------------------------------------------------------------------------------------------------------ 235
 236 ------------VTELHPEVAAKKSQLVELAKQ---KGI-QIMITEG-HRSEERQNELYEQG-R---TT---------------E--------------G-Q-IVTSARGG--ESYHN---------------Y--GLAIDFAIR-V----S-------EDK----VIWDM-----EYDGNNNGESDWM------------------------EVVAIA--KN----LG--F------KW----GGD-W------------------------------V-N-FP-----DYP----HLQYDFGYSIAELQRG------------------------------------------------------------------------------------------------------------------------------------------------------ 236
 237 ------------PTELHPKVGQATEKLIKQSED---IGI-SIIITDG-LRSVEEQNAIYEQG-R---SQ---------------E--------------G-K-IVTYAKGG--ESYHN---------------Y--GLAVDFALE-P----S-------DGQ----VIWDT-----EYDGNSNGQSDWM------------------------EVVDIA--KS----LG--F------SW----GGD-F------------------------------S-R-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 237
 238 -------------------------KLVKEAEN---IGI-ELIITET-IRSYDEQNALYEQG-R---TT---------------E--------------G-N-IVTHAQGG--ESYHN---------------Y--GLAIDYALS-D----Q-------DGN----LIWDL-----NYDGNGNGDSDWF------------------------EVADIA--KD----LG--F------EW----GGD-W------------------------------E-K-FQ-----DYP----HLQMTF---------------------------------------------------------------------------------------------------------------------------------------------------------------- 238
 239 -------------ESLHPTVDKQLSKLIEQSKE---KNI-DIVITAG-VRSKEEQNQLYKQG-R---SK---------------E--------------G-N-IVTHAKAG--ESYHN---------------Y--GLAVDYALR-N----K-------KGE----IRWDM-----NYDGNGNGKSDWV------------------------EVAELA--KD----LG--F------EW----GGD-W------------------------------S-G-FK-----DYP----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 239
 240 ------------------------EKLVDQAAE---KNI-DVVITET-VRSHEEQDALYEQG-R---SK---------------K--------------G-S-IVTYAEGG--ESYHN---------------Y--GLAVDYALR-N----H-------NGK----IIWNT-----SYDGNNNGESDWF------------------------EVADIA--KE----LG--F------EW----GGD-W------------------------------S-N-FK-----DYP----HLQMDFGLSIDQLKRG------------------------------------------------------------------------------------------------------------------------------------------------------ 240
 241 ------------PEGLHPIVGQKAQELAGLAAE---RGI-RIEITDG-FRSHEEQDQLYEQG-R---TA---------------Y--------------G-P-VVTHAKGG--QSYHN---------------F--GLAIDYAIR-T----T-------DGR----LVWDT-----GYDGNGNGKSDWF------------------------EVADIA--KE----LG--F------EW----GGD-W------------------------------S-G-FK-----DYP----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 241
 242 --------------GLHPIVAERAEILRQRAAS---IGI-VIRFTDD-FRSFEEQDALYAQG-R---TE---------------P--------------G-Y-IVTNARGG--QSYHN---------------Y--GLAVDYAL--E----V-------GHQ----VIWDI-----EYDGNGNGRSDWF------------------------EVAQMA--KE----LG--F------TW----GGD-W------------------------------E-S-FR-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 242
 243 ------------IAGLHPIVAEKADELVAQTGK---LGI-KIMITDD-FRSSEEQNTLYKKG-R---SE---------------P--------------G-Q-VVTNVKGG--ASYHN---------------Y--GLAVDFALV-K----P-------DGD----VIWDM-----EYDGNGNGKSDWM------------------------EVVSAA--KK----LG--F------AW----GGD-W------------------------------T-S-FK-----DYP----HLQMDFGYSIKDLQNGKRPP-------------------------------------------------------------------------------------------------------------------------------------------------- 243
 244 -----------------------AGELIRIAAE---KGI-TIQLVED-FRSIESQNQLFAKG-R---TE---------------P--------------G-N-IVTYAQGG--ESYHN---------------Y--GLAVDFALK-G----P-------NGS----LIWDR-----SYDMNGNSKGDWG------------------------EVASIA--KS----LG--F------EW----GGD-W------------------------------E-N-FK-----DYP----HLQMSFGLSISDLQRGKRPPGS------------------------------------------------------------------------------------------------------------------------------------------------ 244
 245 --------------QLHPIVRQQADELVRLAKK---QGI-RILITDG-FRSAAEQDALYRKG-R---SD---------------D--------------G-S-IVTKAKGG--QSYHN---------------F--GLAVDFALL-K----D-------DGS----ASWEM-----NADLNDNGKSDWQ------------------------EVVAIA--KS----LH--F------EW----GGD-W------------------------------D-S-FP-----DYP----HLQMTFGYSIRELQRGADLSAMTLEDAE------------------------------------------------------------------------------------------------------------------------------------------ 245
 246 -------------TELHPTVEEKKNKLIEQAVT---KDI-HVVITDD-VRSFERQEELYQQG-R---AT---------------D--------------G-E-IVTYAQGG--ESYHN---------------Y--GLAIDYALE-N----K-------NGE----LIWDI-----HYDGNNNNQSDWF------------------------EVANIA--KN----LG--F------EW----GGD-W------------------------------E-G-FK-----DYP----HLQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 246
 247 -------------SELHPVVEKAKNELVDQASK---KDI-DVMITDE-VRSKERQDELYARG-R---TT---------------E--------------G-T-VVTHAQGG--ESYHN---------------Y--GLAIDYAIK-N----N-------NGN----VLWDI-----HYDGNNNGESDWF------------------------EVAEIA--KE----IG--F------EW----GGD-W------------------------------Q-H-FK-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 247
 248 --------------------------LIDQASE---IGI-TIVITDG-YRTFAEQDELYARG-R---QD---------------D--------------G-Q-IVTHAQGG--ESYHN---------------Y--GLAIDYALM-N----D-------AGE----VIWDI-----DYDGNGNGKSDWY------------------------EVAEIA--ES----LG--F------EW----GGR-W------------------------------T-H-FP-----DYP----HLQMTF---------------------------------------------------------------------------------------------------------------------------------------------------------------- 248
 249 -------------SELHPDVQEAVDTLIDRADD---IDI-EVVITDG-LRTEEEQETLYARG-R---EN---------------E--------------E-D-IVTHARAG--ESYHN---------------Y--GLAVDYAIR-N----H-------DGE----VIWDI-----HYDGNNNGESDWF------------------------EVADIA--KE----LG--F------EW----GGD-F------------------------------N-S-FT-----DYP----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 249
 250 -----------IPTELHPIVEENKNILLKKAAE---IDI-DVMITEG-LRPFEKQDELYNQG-R---ST---------------K--------------G-N-IVTYSKGG--ESFHN---------------Y--GLAFDYAIK-N----T-------NDG----IEWDI-----EYDGNHNGQSDWF------------------------EVAELA--KE----LG--F------EW----GGD-W------------------------------R-K-FK-----DYP----HLQMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 250
 251 -------------DELHPIVAEKTEQLIEQASQ---IGI-AIIITDG-FRTIEEQDALYQQG-R---ST---------------N--------------G-S-IVTHVAGG--ESLHN---------------Y--GLAVDYALL-N----E-------NGQ----PIWDL-----EYDGNHNGESDWI------------------------EVADIA--KD----LG--F------KW----GGD-W------------------------------K-H-FV-----DYP----HLEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 251
 252 -------------------------QLIEHAAA---VGI-DLMITDG-FRSIEEQNELFRQG-R---SA---------------G--------------G-K-IVTNAMGG--QSLHN---------------F--GLAVDYALL-N----Q-------SGQ----PIWDL-----TYDGNNNGEPDWF------------------------EVAELA--KD----LG--F------EW----GGD-W------------------------------T-D-FV-----DFP----HLQMTFGY-------------------------------------------------------------------------------------------------------------------------------------------------------------- 252
 253 -------------------------QLIEHAAA---VGI-DLMITDG-FRSIEEQNELFRQG-R---SA---------------G--------------G-K-IVTNAMGG--QSLHN---------------F--GLAVDYALL-N----Q-------SGQ----PIWDL-----TYDGNNNGEPDWF------------------------EVAELA--KD----LG--F------EW----GGD-W------------------------------T-D-FV-----DFP----HLQMTFGY-------------------------------------------------------------------------------------------------------------------------------------------------------------- 253
 254 ---------------LHPVVADYTEKLIEEAEA---IGI-SILITDG-YRTPEEQDRLYQKG-R---DQ---------------H--------------G-R-IVTNAKGG--QSYHN---------------F--GLAIDFALL-D----E-------GGE----PLWDI-----AYDGNENGEPDWF------------------------EVAELA--KE----LG--F------EW----GGD-W------------------------------A-N-FT-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 254
 255 -----KANRKLDDPGLNPVVREMGKQLVKLAYA---QGV-PVCITQA-YRSKAEQDALYAQG-R---TK---------------A--------------G-K-VVTNAPGG--YSNHN---------------Y--GLAIDFALY-T----P-------SGL---EVTWSE-----SADYDRDGEADWK------------------------EIVRIA--KK----LG--F------EW----GGD-W------------------------------R-G-FR-----DAP----HLEYTFGLTIAQLRAGKKP--------------------------------------------------------------------------------------------------------------------------------------------------- 255
 256 ------ARSAAYLVGLLPAVKLAAEKLIERCYSE---GV-EIRLTAG-YRSAAEQQRLYEQG-R---TK---------------P--------------G-P-IVTNAKPG--QSNHN---------------Y--GLAIDFVLV-Q----SGYSMSVDDDH--DGI---------------AD---WA------------------------EVVAQA--KL----LG--F------SW----GGD-W------------------------------I-S-FK-----DYP----HFEMMF---------------------------------------------------------------------------------------------------------------------------------------------------------------- 256
 257 ------KSAAEITDRLNPAVKLGLEKLVERCYA---RGV-EIRITSG-YRSAAQQQAIYDQG-RTTASK--------------AK--------------GEK-IVSNAQPG--YSMHN---------------Y--GLAGDFVLT-K----N---------------GYDL-----TADSNHNGVSDWL------------------------EVVTQA--KL----LG--F------EW----GGD-W------------------------------I-S-FK-----DRP----HIQMAFGLGVTKQLLKGIRPTQAQIDDTIKKINALEDDSDMATNKELETKVQTQAEAIEAQEKRMLA--------------------------------------------------------------------------------------------------- 257
 258 ------------------------------------LGL-EVRLTSG-YRSADEQNALYAQG-R---SK---------------P--------------G-Q-VVTNAKAG--ESYHN---------------Y--GLAVDF-VI-I----H-------NNR----ADYDL-----ESDHNRSDEPDWQ------------------------ELGELG--KA----LG--F------EW----GGD-W------------------------------R-S-FP-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 258
 259 ------------------------------------LGL-EVRLTSG-YRSADEQNALYAQG-R---SK---------------P--------------G-Q-VVTNAKAG--QSYHN---------------Y--GLAVDF-VI-I----H-------NNR----ADYNL-----ESDHNRSDEPDWQ------------------------ELGELG--KA----LG--F------EW----GGD-W------------------------------R-S-FP-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 259
 260 ------------------------------------LGL-EVRLTSG-YRSADEQNALYAQG-R---SK---------------P--------------G-Q-VVTNAKAG--QSYHN---------------Y--GLAVDF-VI-I----H-------DNR----ADYDL-----NADHNKSGEPDWQ------------------------ELGELG--KA----LG--F------EW----GGD-W------------------------------R-S-FP-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 260
 261 --------------------------------SC--LGL-EVRLTSG-YRSEDEQNALYAQG-R---SE---------------P--------------G-Q-IVTNAKAG--QSYHN---------------Y--GLAVDF-VI-I----H-------DNR----ADYDL-----SSDHNRSGVPDWQ------------------------ELGELG--KA----LG--F------EW----GGD-W------------------------------R-N-FP-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 261
 262 ---------------LHPLVANRGESFIRLAHSC--LDL-EVRLTSG-YRSAKEQNALYAQG-R---SE---------------P--------------G-Q-VVTNAKAG--QSYHN---------------Y--GLAVDF-VI-I----H-------NNK----TDYDL-----NTDRNRNDIPDWQ------------------------ELGELG--KA----LG--F------EW----GGD-W------------------------------N-S-FP-----DYP----HLQM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 262
 263 -----------------------------VSHSC--YNI-DIRITQG-YRTNKQQDVLYEQG-R---SR---------------A--------------G-D-VVTNARGG--ESMHN---------------Y--GLAIDF-VQ-M----V-------DGD----ISYDL-----EYDGNQSGKSDWR------------------------EVAAVG--KA----LG--F------EW----GGD-W------------------------------K-R-FV-----DYP----HFEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 263
 264 ---------------LHPAVRAGAKDLIRLSHSC--YNI-DIRITQG-YRTKKQQDALYEQG-R---SQ---------------A--------------G-E-VVTNARGG--ESMHN---------------Y--GLAIDF-VQ-M----I-------DGD----ISYDL-----EYDGNQSGKSDWR------------------------EVAAVG--KA----LG--F------EW----GGD-W------------------------------K-R-FV-----DYP----HFEM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 264
 265 --------SEANLKRLHPAVEAGAKDLIRVAHSC--YNI-DIKITQG-YRSIQQQNTLFEQG-R---SE---------------A--------------G-E-VVTNARGG--ESMHN---------------Y--GLAIDF-VQ-L----V-------NGQ----ISYDL-----EYDGNRSGKSDWR------------------------EVADIG--KA----LG--F------EW----GGD-W------------------------------K-R-FV-----DYP----HFEMTFGYSLDELKAGERPSRSEK---------------------------------------------------------------------------------------------------------------------------------------------- 265
 266 ----LINASETNLKRLHPAVEAGAKDLIRVAHSC--YNI-DIKITQG-YRSIQQQNALYEQG-R---SK---------------A--------------G-E-VVTNARGG--ESMHN---------------Y--GLAVDF-VQ-L----V-------NGE----ISYDL-----EYDGNRSGKSDWR------------------------EVADIG--KA----LG--F------EW----GGD-W------------------------------K-R-FV-----DYP----HFEMTFGYSLDELKAGERP--------------------------------------------------------------------------------------------------------------------------------------------------- 266
 267 -----------------------------------------------------------------------------------------------------------------QSNHN---------------Y--GLAIDYVLL-S----E-------DGK---KALWTV-----N--------EKWR------------------------RVAQIG--KS----LG--F------SW----GGD-W------------------------------K-S-FK-----DYP----HLEM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 267
 268 -------------SGIHKIVKESAIEMIKQAYK---EGI-FVQITSG-YRSFAEQNKLYAQG-R-----------------TA-P--------------G-K-IVTNAKGG--QSNHN---------------Y--GLAIDYVLL-S----A-------DGK---KALWTV-----N--------EKWR------------------------RVAQIG--KS----LG--F------SW----GGD-W------------------------------K-S-FK-----DYP----HLEMMGSLTLTQLQAGKRP--------------------------------------------------------------------------------------------------------------------------------------------------- 268
 269 ----------------------------TRSYN---EGI-NVQISSG-YRSNTQQASIYGMG-R---PN----YWWNGKHYGN-T--------------G-S-IVSNAQPG--QSIHN---------------Y--GLAIDYFLV-S----D-------DGL---KAIWVV-----N--------AQWR------------------------RVAQIG--KS----LG--F------TW----GGD-W------------------------------K-G-FV-----DAP----HLEY------------------------------------------------------------------------------------------------------------------------------------------------------------------ 269
 270 ---------------IHPVVKESALEMVKRAYQ---ESI-FVQISAG-YRSMEEQAKLYGQG-R---LG----YIYDGKNYSDLS--------------K-P-RVTNAKPG--QSYHN---------------Y--GLAIDYFIV-S----D-------DGK---NAKWTV-----D--------AKWR------------------------RVAAIG--KS----LG--F------AW----GGD-W------------------------------S-N-FK-----DYP----HLDMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 270
 271 ------RSVKKMGKGMNPVVKAAALEMVERAYN---EGI-TVQISAG-YRSLEEQATLFGQG-R---V-----YSYKGKNYSNLA--------------K-P-IVTNAKPG--QSYHN---------------Y--GLAIDFFIV-S----D-------DGR---RAIWTV-----N--------SKWQ------------------------RVAAIG--KG----LG--F------KW----GGD-W------------------------------S-S-FK-----DYP----HLE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 271
 272 ------RSITNMKDGINPTVKKSALELIRRAYE---ENI-FVLITSG-FRSMEEQAALYGQG-R---ES----YVYNGKDYGDPT--------------K-P-IVTQVKPG--KSNHN---------------F--GLAIDFVLL-S----E-------DGN---RAIWDV-----N--------DNWI------------------------RVANMG--KE----LG--F------KW----GGD-W------------------------------T-S-FK-----DYP----HLEM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 272
 273 -----------------KVVEEKATQLVSIAYR---EGI-YVQISSG-YRSLAEQARLYGKG-R---PF----FVWKGKNYGK-K--------------G-K-IVTYAKPG--ESIHN---------------K--GRAIDFFLV-S----K-------DGR---TALWKV-----D--------ERWH------------------------RVGAIG--KS----LG--F------SW----GGD-W------------------------------K-T-FK-----DYP----HLELA----------------------------------------------------------------------------------------------------------------------------------------------------------------- 273
 274 -----ERSIRNMGN-VQAEVRKRALEFIELAYK---KRI-PVQISSG-FRSMEEQARLYGQG-R---PN----YVWQGKKYGS-K--------------G-N-IVTKAQPG--QSNHN---------------K--GWAIDYFIV-S----E-------DGT---KALWKV-----D--------EKWR------------------------QAASIA--KS----LG--F------SW----GGD-W------------------------------K-S-FP-----DYP----HLEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 274
 275 -----------------------------RAYS---EGI-NVQISSG-LRTNDEQNRLYAKG-R---TA---------------S--------------G-N-IVTNARAG--QSVHN---------------Y--GLAVDYFLT-N----R-------TGD---TAVWTV-----N--------DQWK------------------------RVAAIA--KS----MG--F------TW----GGD-W------------------------------T-S-FP-----DAS----HLEY------------------------------------------------------------------------------------------------------------------------------------------------------------------ 275
 276 -----------------------------RAYK---EGI-NVQISSG-LRTHAEQNALYAKG-R---TA---------------P--------------G-N-IVTNARAG--QSVHN---------------Y--GLAVDYFLT-N----H-------TGT---TATWTV-----N--------AQWR------------------------RVAAIA--KS----MG--F------TW----GGD-W------------------------------T-S-FP-----DAP----HLEY------------------------------------------------------------------------------------------------------------------------------------------------------------------ 276
 277 ----------------------------KRAY-K--EGI-WVQYSAG-YRSYAEQNALYAQG-R---TK---------------P--------------G-S-IVTNARGG--YSNHN---------------F--GLAVDYFLY-D----D-------NGK--A--HWNV-----N--------SDWK------------------------RVAQIA--KD----LG--F------EW----GGD-W------------------------------K-S-FY-----DAP----HLEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 277
 278 --LIDKSNKRLGVSGLNKVVYESAIEVIKRAY-K--EGI-WVQYSAG-YRSYAEQNALYAQG-R---TK---------------P--------------G-S-IVTNARGG--YSNHN---------------F--GLAVDYFLY-D----D-------NGK--A--HWNV-----N--------SDWK------------------------RVAQIA--KD----LG--F------EW----GGD-W------------------------------K-S-FY-----DAP----HLEMTGGLSTAQLRA------------------------------------------------------------------------------------------------------------------------------------------------------- 278
 279 -QTLLNRAKENMGSGMNPVVNETILEVVKLAYE---AGI-FVQITAG-YRSFREQNELYERG-R---TN-------------K-S--------------K-P-IVTYARGG--QSLHN---------------Y--GLAVDFVIV-S----D-------DGK---RALWTE-----G--------EKWT------------------------RVAAIA--KS----LG--F------VW----GGD-F------------------------------E-L-FR-----DFP----HLGMSGGLS------------------------------------------------------------------------------------------------------------------------------------------------------------- 279
 280 ---------------VQPVVKEKVFELIERAYE---RGI-FAQISSG-HRTWEEQAHLYGKG-R------------------------PDYYWKGKRYGHSGSIVTYAPPG--KSNHH---------------S--GRAVDFFLVSA------------DGK---NALWTV-------------NANWR------------------------EVAKIA--KS----LG--F------QW----GGD-W------------------------------T-S-FK-----DYA----HLEWP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 280
 281 ------RSLERIGE-VHMEVKKKVIELIDAAYE---EGI-AVQMSSG-YRSHTQQAAIYGQG-R---PG----YHWNGVHYGS-A--------------G-R-IVTYAEPG--ESNHH---------------S--GRAVDFFLV-S----P-------EGN---EALWVV-----D--------SRWR------------------------RVAALA--KG----LG--F------SW----GGD-W------------------------------K-S-FK-----DYA----HLEW------------------------------------------------------------------------------------------------------------------------------------------------------------------ 281
 282 ----------------------------------------VVRFSWT-FRSFEEQDKIYQQG-R---TT---------------P--------------G-S-IVSNAKAG--ESFHN---------------Y--GLAIDIVLL-V----D----KDVNGTFETA-SWST-----KADFDKDGQSDWS------------------------EVVEVF--KK----YG--W------EW----GGD-W------------------------------R-R--R-----DDP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 282
 283 ----------------------------------------VVRFSWT-FRSFEEQDKIYQQG-R---TT---------------P--------------G-S-IVSNAKAG--ESFHN---------------Y--GLAIDIVLL-V----D----KDVNGTFETA-SWST-----KADFDKDGQSDWS------------------------EVVEVF--KK----YG--W------EW----GGD-W------------------------------R-R--R-----DDP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 283
 284 ----------------------------------------VVRFSWT-FRSFEEQDKIYQQG-R---TT---------------P--------------G-S-IVSNAKAG--ESFHN---------------Y--GLAIDIVLL-V----D----KDVNGTFETA-SWST-----KADFDKDGQSDWS------------------------EVVEVF--KK----YG--W------EW----GGD-W------------------------------R-R--R-----DDP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 284
 285 ----------------------------------------VVRFSWT-FRSFEEQDKIYQQG-R---TT---------------P--------------G-S-IVSNAKAG--ESFHN---------------Y--GLAIDIVLL-V----D----KDVNGTFETA-SWST-----KADFDKDGQSDWS------------------------EVVEVF--KK----YG--W------EW----GGD-W------------------------------R-R--R-----DDP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 285
 286 ----------------------------------------VVRFSWT-FRSFEEQDKIYQQG-R---TT---------------P--------------G-S-IVSNAKAG--ESFHN---------------Y--GLAIDIVLL-V----D----KDVNGTFETA-SWST-----KADFDKDGQSDWS------------------------EVVEVF--KK----YG--W------EW----GGD-W------------------------------R-R--R-----DDP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 286
 287 ------------IKTIHPQLRTELLEIYNEILE---RGV-GVRFTSV-LRSFKEQDAIYAQG-RW--GN---------------P--------------G-S-IVSHARGG--QSYHN---------------Y--GLAVDFCLL-K----T-------NGQ----VSWNR-----SDDLDRDGQSDWM------------------------EIASAF--KM----YG--W------EW----GGD-W------------------------------N-S-FK-----DYP----HVQKTFGY-------------------------------------------------------------------------------------------------------------------------------------------------------------- 287
 288 ---------------MHPKIREEVREIYLQINTALPKGV-RLRLSQT-LRTFKEQDELFNK--R---PK-----------------------------------VTNAKGG--QSIHN---------------Y--GLAFDIVI---------------------LYDKDSNGSFETASWALDIN--FM------------------------KVVNFF--KS----KG--W------TW----GGD-W------------------------------K-S-FK-----DYP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 288
 289 ----------ERIDQIHPRLRADLKNDYEFINSQLPKNV-RLRFTFT-YRSIDEQNDLYAQG-R---TK---------------P--------------G-K-IVTNAKGG--QSMHN---------------Y--GLAFDIVL---------------------LFDYDNNESFETANWDLNEI--FM------------------------KVVNYF--KA----KG--W------EW----GGD-W------------------------------K-R-FK-----DYP----HFQMTFGNDLKKLKA------------------------------------------------------------------------------------------------------------------------------------------------------- 289
 290 --------------------REEVKQIIKECDQALTGRA-KIRITQG-LRSFEEQEKLYAIG-R---IT---------------S--------------G-K-KVTNAKAG--QSIHN---------------Y--GLAVDICLM-I------------DGK---TASWDT-----VKDWDNDKVADWY------------------------ECVKIF--AK----HG--W------DW----GGN-W------------------------------K-T-FK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 290
 291 --------------------REEVKQIIKECDESLTGRA-KIRITQG-LRTFEEQEKLYAIG-R---IT---------------S--------------G-K-KVTNAKAG--QSIHN---------------Y--GLAVDICLM-I------------DGK---TASWDT-----VKDWDNDRVADWY------------------------ECVKIF--AK----HG--W------DW----GGN-W------------------------------K-T-FK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 291
 292 --------------------REEVKQIIQECDKALTGRA-KVRITQG-LRSFEEQEKLYAIG-R---IT---------------S--------------G-K-KVTNAKAG--QSIHN---------------Y--GLAVDICMM-I------------DGK---TASWDT-----VKDWDNDKVADWY------------------------ECVKIF--AK----HG--W------DW----GGN-W------------------------------K-T-FK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 292
 293 --------------------REEVKQIIKECDEALTGKA-KVRITQG-LRSFEEQEKLYAIG-R---IT---------------S--------------G-R-KVTNAKAG--QSIHN---------------Y--GLAVDICLI-I------------DGK---AASWDT-----VKDWDNDKVADWY------------------------ECVKIF--AK----HG--W------DW----GGN-W------------------------------K-T-FK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 293
 294 ---------------------TEVKQIIKECDDALTGIA-KIRITQG-LRSFEEQEKLYAIG-R---IT---------------S--------------G-K-KVTNAKAG--QSIHN---------------Y--GLAVDICLM-I------------DGK---TASWDT-----AKDWDNDKVADWY------------------------ECVKIF--AK----HG--W------DW----GGN-W------------------------------K-T-FK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 294
 295 --------------------REEVKQIIKECDAALTGKA-KIRITQG-LRSFEEQEKLYAIG-R---VT---------------S--------------G-K-KVTNAKAG--QSIHN---------------Y--GLAVDMCLI-I------------DGK---TASWDT-----AKDWDNDKIADWY------------------------ECVKIF--AK----HG--W------DW----GGN-W------------------------------K-T-FK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 295
 296 ---------------------DEVKQIIKECDEALTGRA-KIRITQG-LRSFEEQEKLYAIG-R---IT---------------A--------------G-K-KVTNAKAG--QSIHN---------------Y--GLAVDICLM-I------------DGK---TASWDT-----AKDWDNDQVADWY------------------------ECVKIF--AR----HG--W------DW----GGN-W------------------------------K-T-FK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 296
 297 ---------------LHPLVRDEVKQIIQECDEALTGRA-KIRITQG-LRSFEEQEKLYAIG-R---IT---------------S--------------G-K-KVTNAKAG--QSIHN---------------Y--GLAVDICLM-I------------DGK---TASWDT-----VKDWDNDKVADWY------------------------ECVKIF--AR----YG--W------DW----GGN-W------------------------------K-T-FK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 297
 298 ---------------------DEVKQIIKECDEALTGRA-KVRITQG-LRSFEEQEKLYAIG-R---IT---------------S--------------G-K-KVTNAKAG--QSIHN---------------Y--GLAVDICLM-I------------DGK---VASWDT-----VKDWDNDRVADWY------------------------ECVKIF--AR----HG--W------DW----GGN-W------------------------------K-T-FK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 298
 299 ---------------------KEVRQIIQDCDEALTGRA-KVRITQG-LRSFEEQEKLYAIG-R---LT---------------S--------------G-K-KVTNAKAG--QSIHN---------------Y--GLAVDICLI-I------------DGK---IASWDT-----AKDWDNDKVADWY------------------------ECVKIF--AR----HG--W------DW----GGN-W------------------------------K-T-FK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 299
 300 --------------------REEAKQIIKACDEALTGRA-KIRITQG-LRSFEEQERLYAIG-R---LT---------------T--------------G-R-KVTNAKAG--QSIHN---------------Y--GLAVDICLI-I------------DGK---TASWDT-----AKDWDNDGVADWY------------------------ECVKVF--AK----YG--W------DW----GGN-W------------------------------K-T-FK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 300
 301 --------------------REEVRQIIEECDKTLTGRA-KIRVTQG-LRSFEEQEKLYAIG-R---IT---------------K--------------D-K-KVTNAKAG--QSIHN---------------Y--GLAVDICLI-T------------DGK---AVSWDN-----AKDWDNDGIADWY------------------------ECVKIF--AK----YG--W------DW----GGN-W------------------------------K-T-MK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 301
 302 --------------------------------IALSERA-KIRITQG-FRTIEEQNELYAKG-R---TI---------------S--------------G-K-KVTNAKGG--QSIHN---------------Y--GFAVDICLI-I------------DGK---KASWDT-----MKDWDGDKVADWF------------------------ECVKIF--AK----YN--W------DW----GGN-W------------------------------K-T-FK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 302
 303 -------------------------------------------ITQG-LRTFKEQDELYAQG-R---TK---------------P--------------G-K-KVTNAKAG--QSIHN---------------Y--GLAVDICLI-I------------DGK---TVSWDT-----AKDWDNDGVADWY------------------------ECVKIF--AK----YG--W------EW----GGN-W------------------------------K-T-FK-----DLP----HFERRHIWKGDRKINASWRNLQNLPKDKDGYVV------------------------------------------------------------------------------------------------------------------------------------- 303
 304 ---------------LHPLVRDEVTKIINECNQSLTGRA-QVRITQG-LRTFKEQEDLYALG-R---TK---------------P--------------G-K-KVTNVKGG--QSIHN---------------Y--GFAVDICLI-I------------DGK---VASWDT-----VKDWDNDGVADWY------------------------ECVKIF--AK----HG--W------DW----GGN-W------------------------------K-T-FK-----DLP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 304
 305 -------------------------------------------VTQS-LRTFQEQEDLYAFG-R---TK---------------P--------------G-K-KVTNAKGG--QSIHN---------------Y--GFAVDICLI-I------------DGK---TASWDT-----AKDWDDDRISDWQ------------------------ECVKIF--KK----YN--W------NW----GGD-W------------------------------K-T-FK-----DLP----HFD------------------------------------------------------------------------------------------------------------------------------------------------------------------- 305
 306 -------------------------------------------ITQS-LRTFQEQEDLYAFG-R---TK---------------P--------------G-K-KVTNAKGG--QSIHN---------------Y--GFAVDICLI-I------------DGN---TASWDT-----AKDWDNDQIADWQ------------------------ECVNIF--KK----YN--W------NW----GGD-W------------------------------K-T-FK-----DLP----HFD------------------------------------------------------------------------------------------------------------------------------------------------------------------- 306
 307 -------------------------------------------ITQG-LRTFQEQEDLYAFG-R---TK---------------P--------------G-K-KVTNAKGG--QSIHN---------------Y--GFAVDICLI-I------------DGK---TASWDT-----AKDWDDDQVSDWQ------------------------ECVDIF--KK----HG--W------NW----GGD-W------------------------------K-T-FK-----DLP----HFD------------------------------------------------------------------------------------------------------------------------------------------------------------------- 307
 308 ---------------------EEVMQIIKDCDTALTGRA-KVRITQG-LRTYAEQAKLYAQG-R---TI---------------P--------------G-L-KVTNARPG--QSIHN---------------Y--GLAVDICLI-I------------DGK---TASWDI-----AKDWDGDRIADWQ------------------------ECVRIF--NR----YG--W------EW----GGN-W------------------------------K-T-FK-----DYP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 308
 309 ---------------LHPVIREEVMQIIKDCDTALTGRA-KVRITQG-LRTYAEQAKLYAQG-R---TT---------------P--------------G-L-KVTNARPG--QSIHN---------------Y--GLAVDICLI-I------------DGK---TASWDI-----AKDWDGDRVADWQ------------------------ECVRIF--NR----YG--W------EW----GGN-W------------------------------K-T-FK-----DYP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 309
 310 ---------------------EEVMQIIKDCDTALTGRA-KVRITQG-LRTYAEQAKLYAQG-R---TT---------------T--------------G-L-KVTNARPG--QSIHN---------------Y--GLAVDICLI-I------------DGK---TASWDI-----AKDWDGDRIADWQ------------------------ECVKIF--NR----YG--W------EW----GGN-W------------------------------K-T-FK-----DYP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 310
 311 ---------------------EEVMQIIKDCDTALTGRA-KIRITQG-LRTHAEQAKLYAQG-R---TT---------------P--------------G-L-KVTNARPG--QSIHN---------------Y--GLAVDICLI-I------------DGK---TASWDI-----AKDWDGDRIADWQ------------------------ECVKIF--NR----YG--W------EW----GGN-W------------------------------K-T-FK-----DYP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 311
 312 ---------------------EEVMQIIKDCDKALTGRA-KIRITQG-LRTHAEQAKLYAQG-R---TT---------------P--------------G-L-KVTNARPG--QSIHN---------------Y--GLAVDICLI-I------------DGK---TASWDI-----AKDWDGDRIADWQ------------------------ECVKIF--SR----YG--W------EW----GGN-W------------------------------K-T-FK-----DYP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 312
 313 --------TLANIEKLHPMIREEVKQIIKECDTALTGRA-KIRITQG-FRTFQEQAKLYAQG-R---TL---------------P--------------G-K-KVTNARPG--QSIHN---------------Y--GLAVDMCLV-I------------DGK---TISWDI-----AKDWDNDRIADWK------------------------ECVNVF--AK----YG--W------EW----GGS-W------------------------------K-T-FK-----DYP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 313
 314 -------------------------CIINECNKALTGRA-QIRISQG-LRTFSEQDELYAQG-R---TK---------------P--------------G-K-KVTNAKGG--QSVHN---------------Y--GFAVDGVLI-L------------DGK---TASWDF-----KKDFDNDGVADWD------------------------ECVKIF--AK----YG--W------SW----GGN-W------------------------------T-S-FK-----DFP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 314
 315 ------------------------RAVITQMHAQ---GI-YICVAQG-FRSFAEQDALYAQG-R---TK---------------P--------------G-S-IVTNARGG--QSNHN---------------Y--GVAVDLCL--Y----T------QDGS--DVI-W-T-----VE----GN---FR------------------------KVIAAM--KA----QG--F------KW----GGD-W------------------------------V-S-FK-----DYP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 315
 316 ------------------------RAVITQMHAQ---GI-YICVAQG-FRSFAEQNALYAQG-R---TK---------------P--------------G-S-IVTNARGG--QSNHN---------------Y--GVAVDLCL--Y----T------QDGS--DVI-W-T-----VE----GN---FR------------------------KVIAAM--KA----QG--F------KW----GGD-W------------------------------V-S-FK-----DYP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 316
 317 --LIDKANRKLNVSGMRKDVADRTRAVITQMHAQ---GI-YICVAQG-FRSFAEQNALYAQG-R---TK---------------P--------------G-S-IVTNARGG--QSNHN---------------Y--GVAVDLCL--Y----T------QDGS--DVI-W-T-----VE----GN---FR------------------------KVIAAM--KA----QG--F------KW----GGD-W------------------------------V-S-FK-----DYP----HFELYDVVGGQKPPA------------------------------------------------------------------------------------------------------------------------------------------------------- 317
 318 -------------------------AVITQMHAQ---GI-YICVAQG-FRSFAEQDALYAQG-R---TK---------------P--------------G-N-IVTNARGG--QSNHN---------------Y--GVAVDLCL--Y----T------QDGS--DVI-W-T-----VE----GN---FR------------------------KVIAAM--KG----QG--F------KW----GGD-W------------------------------V-S-FK-----DYP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 318
 319 -------------------------AVITQMHAQ---GI-YICVAQG-FRSFAEQDALYAQG-R---TK---------------P--------------G-N-IVTNARGG--QSNHN---------------Y--GVAVDLCL--Y----T------QDGS--DVI-W-T-----VE----GD---FR------------------------KVIAAM--KG----QG--F------KW----GGD-W------------------------------V-S-FK-----DYP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 319
 320 --------------------------VIKEMAKQ---GI-YINVAQG-FRSIAEQNELYAQG-R---TK---------------P--------------G-N-VVTNAKGG--QSNHN---------------Y--GVAVDLCQ--Y----T------QDGK--DVI-W-A-----VD----AK---FK------------------------KIVDAM--KK----QG--F------KW----GGD-W------------------------------K-S-FK-----DNP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 320
 321 --------------------------VIKEMAKQ---GI-YINVAQG-FRSIAEQNELYAQG-R---TK---------------P--------------G-N-VVTNAKGG--QSNHN---------------Y--GVAVDLCQ--Y----T------QDGK--DVI-W-A-----VD----AK---FK------------------------KIVDAM--KK----QG--F------KW----GGD-W------------------------------K-S-FK-----DNP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 321
 322 --------------------------VIKEMAKQ---GI-YINVAQG-FRSIAEQNELYAQG-R---TK---------------P--------------G-N-VVTNAKGG--QSNHN---------------Y--GVAVDLCQ--Y----T------QDGK--DVI-W-A-----VD----AK---FK------------------------KIVAAM--KK----QG--F------KW----GGD-W------------------------------K-S-FK-----DNP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 322
 323 --------------------------VIKEMAKQ---GI-YINVAQG-FRSIAEQNELYAQG-R---TK---------------P--------------G-N-VVTNAKGG--QSNHN---------------Y--GVAVDLCQ--Y----T------QDGK--DVI-W-A-----VD----AK---FK------------------------KIVAAM--KK----QG--F------KW----GGD-W------------------------------K-S-FK-----DNP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 323
 324 --------------------------VIKEMAKQ---GI-YINVAQG-FRSIAEQNELYAQG-R---TK---------------P--------------G-N-VVTNAKGG--QSNHN---------------Y--GVAVDLCQ--Y----T------QDGK--DVI-W-A-----VD----AK---FK------------------------KIVAAM--KK----QG--F------KW----GGD-W------------------------------K-S-FK-----DNP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 324
 325 --------------------SDKTRNVIKKMAKE---GI-YLCVAQG-YRSTAEQNALYAQG-R---TK---------------P--------------G-A-IVTNAKGG--QSNHN---------------F--GVAVDLCL--Y----T------SDGK--DVI-WES-----TT----SR---WK------------------------KVVAAM--KA----EG--F------EW----GGD-W------------------------------K-S-FK-----DYP----HFELCDAVSGEKIPTATQ--NTN----------------------------------------------------------------------------------------------------------------------------------------------- 325
 326 AWLIEKANRKLNTSGMNKATSDKTRNVIKKMAKE---GI-YLCVAQG-YRSTAEQNALYAQG-R---TK---------------P--------------G-A-IVTNAKGG--QSNHN---------------F--GVAVDLCL--Y----T------SDGK--DVI-WES-----TT----SR---WK------------------------KVVAAM--KA----EG--F------EW----GGD-W------------------------------K-S-FK-----DYP----HFELCDAVSGEKIPTATQ--NTNPNRHDGKIVDSAPLLPKMDFKSNPARMYKSGTEFLVYEHNQYWYKTYINDKLYYMYKSFCDVVAKKDAKGRIKVRIKSAKDLRIPVWNNTKLNSGKIKWYAPNTKLAWYNNGKGYLELWYEKDGWYYTANYFLK--------- 326
 327 AWLIEKANRKLNTSGMNKATSDKTRNVIKKMAKE---GI-YLCVAQG-YRSTAEQNALYAQG-R---TK---------------P--------------G-A-IVTNAKGG--QSNHN---------------F--GVAVDLCL--Y----T------SDGK--DVI-WES-----TT----SR---WK------------------------KVVAAM--KA----EG--F------EW----GGD-W------------------------------K-S-FK-----DYP----HFELCDAASGEKIPTATQ--NTNPNRHDGKIVDSAPLLPKMDFKSSPFRMYKAGTEILVYEHNQYWYKTYINDKLYYMYKSFCDVVAKKDAKGRIKVRIKSAKDLRIPVWDNTRLNSGKIKWYKPGTKLSWYDNKKGFLELWYTKDGWYYTANYFLK--------- 327
 328 -----------NVSGMNKVAADKTRNVIKKMAKE---GI-YLCVAQG-YRSTAEQNALYAQG-R---TK---------------P--------------G-A-IVTNAKGG--QSNHN---------------F--GVAVDLCL--Y----T------SDGK--DVI-WES-----TT----SR---WK------------------------KVVAAM--KA----EG--F------KW----GGD-W------------------------------K-T-FK-----DYP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 328
 329 AWLIEKANRKLNAGGMYKITSDKTRNVIKKMAKE---GI-YLCVAQG-YRSTAEQNALYAQG-R---TK---------------P--------------G-A-IVTNAKGG--QSNHN---------------Y--GVAVDLCL--Y----T------NDGK--DVI-WES-----TT----SR---WK------------------------KVVAAM--KA----EG--F------KW----GGD-W------------------------------K-S-FK-----DYP----HFELCDAVSGEKIPAATQNTNTNSNRYEGKVIDSAPLLPKMDFKSSPFRMYKVGTEFLVYDHNQYWYKTYIDDKLYYMYKSFCDVVAKKDAKGRIKVRIKSAKDLRIPIWNNTKLNSGKIKWYAPNVKLAWYNYRRGYLELWYPSDGWYYTANYFLK--------- 329
 330 AWLIEKANRKLNAGGMYKITSDKTRNVIKKMAKE---GI-YLCVAQG-YRSTAEQNALYAQG-R---TK---------------P--------------G-A-IVTNAKGG--QSNHN---------------Y--GVAVDLCL--Y----T------NDGK--DVI-WES-----TT----SR---WK------------------------KVVAAM--KA----EG--F------KW----GGD-W------------------------------K-S-FK-----DYP----HFELCDAVSGEKIPAATQNTNTNSNRYEGKVIDSAPLLPKMDFKSSPFRMYKVGTEFLVYDHNQYWYKTYIDDKLYYMYKSFCDVVAKKDAKGRIKVRIKSAKDLRIPVWNNIKLNSGKIKWYAPNVKLAWYNYRRGYLELWYPNDGWYYTAEYFLK--------- 330
 331 AWLIEKANRKLNAGGMYKITSDKTRNVIKKMAKE---GI-YLCVAQG-YRSTAEQNALYAQG-R---TK---------------P--------------G-A-IVTNAKGG--QSNHN---------------Y--GVAVDLCL--Y----T------NDGK--DVI-WES-----TT----SR---WK------------------------KVVAAM--KA----EG--F------KW----GGD-W------------------------------K-S-FK-----DYP----HFELCDAVSGEKIPAATQNTNTNSNRYEGKVIDSAPLLPKMDFKSSPFRMYKVGTEFLVYDHNQYWYKTYINDKLYYMYKSFCDVVAKKDAKGRIKVRIKSAKDLRIPVWNNTKLNSGKIKWYAPNTKLAWYNNGKGYLELWYPSDGWYYTANYFLK--------- 331
 332 -----------NVSGMDKVTSDKTRNVIKKMSKQ---GI-YLCVAQG-YRSNAEQNALYAQG-R---TK---------------P--------------G-S-VVTNAKGG--QSNHN---------------Y--GVAVDLCL--Y----S------NDGK--NVI-WES-----TT----SR---WK------------------------KVVAAM--KA----EG--F------KW----GGD-W------------------------------K-S-FK-----DYP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 332
 333 AWLIEKANRKLNVSGMNKSVADKTRNVIKKMAKK---GI-YLCVAQG-YRSSAEQNALYAQG-R---TK---------------P--------------G-A-VVTNAKGG--QSNHN---------------Y--GVAVDLCL--Y----T------SDGK--NVI-WES-----TT----SR---WK------------------------TVVSAM--KA----EG--F------EW----GGD-W------------------------------K-S-FK-----DYP----HFELYDAAGGEKAPSTS----------------------------------------------------------------------------------------------------------------------------------------------------- 333
 334 AWLIEKANRKLNVSGMNKSVADKTRNVIKKMAKK---GI-YLCVAQG-YRSSAEQNALYAQG-R---TK---------------P--------------G-A-VVTNAKGG--QSNHN---------------Y--GVAVDLCL--Y----T------SDGK--NVI-WES-----TT----SR---WK------------------------TVVSAM--KA----EG--F------EW----GGD-W------------------------------K-S-FK-----DYP----HFELYDAAGGEKAPSTS----------------------------------------------------------------------------------------------------------------------------------------------------- 334
 335 -------------------------------YEQ---GI-YIGIAQG-YRSTAEQNALYAQG-R---TA---------------P--------------G-Q-KVTNAKGG--QSNHN---------------Y--GCAVDLFI--Y----A------HDGK--SVVAWEP-----PS----T-------------------------------VVKAM--KA----EG--F------KW----GGD-W------------------------------K-G-FV-----DKP----HFELY----------------------------------------------------------------------------------------------------------------------------------------------------------------- 335
 336 -------------------------YVIQKAHAE---GI-YICVVNPCFRSKAEQDALYAQG-R---TK---------------P--------------G-Q-IVTNAKGG--QSNHN---------------F--GVAVDLCL--Y----T------NDGK--NVV-WET-----NT----KR---WL------------------------RVVAIA--KS----VG--F------KW----GGD-W------------------------------T-S-FK-----DYP----HFELY----------------------------------------------------------------------------------------------------------------------------------------------------------------- 336
 337 ----------------------------QKAHEE---GI-YICVVNPCFRSKAEQDALYAQG-R---TK---------------P--------------G-Q-IVTNARGG--QSNHN---------------Y--GVAVDLCL--Y----T------ADGK--NVV-WET-----TS----KR---WL------------------------RVVAIA--KT----VG--F------KW----GGD-W------------------------------T-S-FK-----DYP----HFELY----------------------------------------------------------------------------------------------------------------------------------------------------------------- 337
 338 -------------------------------H-V--KGI-YVGVAQG-FRSYAEQEKLYAQG-R---TA---------------P--------------G-A-IVTNARGG--QSNHN---------------R--GIAVD---L-F----Q----YSMDGA--EA-IFNT-----D--------ANFQ------------------------QIILAM--KR----QG--F------SW----GGD-W------------------------------D-G-FK-----DYP----HFELN----------------------------------------------------------------------------------------------------------------------------------------------------------------- 338
 339 SWLLERANRKLNVPGLSPEVARKTRQVIRELH-V--RGI-YVGVAQG-FRSYAEQEKLYAQG-R---TT---------------P--------------G-A-IVTNARGG--QSNHN---------------R--GIAVD---L-F----Q----YSMDGT--EA-IFNT-----D--------ENFQ------------------------QIVHAM--KR----QG--F------SW----GGD-W------------------------------S-G-FK-----DYP----HFELNKTTTDVLVP-------------------------------------------------------------------------------------------------------------------------------------------------------- 339
 340 ------------------EVAKRTQEVIREMH-A--QGI-YVGVAQG-YRSIAEQNRLYAQG-R---TL---------------P--------------G-P-IVTNARGG--QSSHN---------------R--GIAVD---L-F----Q----YSQDGT--QA-LFRN-----D--------QSFQ------------------------KIVAAM--KR----RG--F------SW----GGD-W------------------------------T-S-FK-----DYP----HFELL----------------------------------------------------------------------------------------------------------------------------------------------------------------- 340
 341 SWLLERANRKLNASGLSREVAKRTQEVIREMH-A--QGI-YVGVAQG-YRSIVEQNRLYAQG-R---TL---------------P--------------G-P-IVTNARGG--QSSHN---------------R--GIAVD---L-F----Q----YSKDGT--QA-LFRN-----D--------QSFQ------------------------KIVAAM--KR----RG--F------SW----GGD-W------------------------------T-S-FK-----DYP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 341
 342 -------------------------------AAE---GL-PIGIAQA-FRTRQEQDALYAIG-R---TR---------------P--------------G-K-IVTYAKGG--ASNHN---------------F--GVAVDLFL--Y----A------DGGK--RAEFLAP-----PD----PR---LQ------------------------RLVRAM--KQ----YQ--M------QW----GGD-W------------------------------G-N-FP-----DYP----HFQLY----------------------------------------------------------------------------------------------------------------------------------------------------------------- 342
 343 --WLLDQANRKLTNGMDPDVAAITRTVITELAAE---GL-PIGIAQG-FRTKQEQDDLYASG-R---TR---------------P--------------G-K-IVTYAKGG--KSNHN---------------F--GVAVDLFV--Y----A------DGGK--RAEFPAP-----PD----PR---LK------------------------RIVAAM--KR----YQ--M------QW----GGD-W------------------------------G-S-FP-----DYP----HFQLYDAVNGQTKP-------------------------------------------------------------------------------------------------------------------------------------------------------- 343
 344 ---------------------------------H---GI-KLGIAQS-FRSIAEQNALYAKG-R---TT---------------Q--------------G-P-IVTQARGG--QSNHN---------------F--GVAIDVFL--Y----E------DG-----ALFLSP-----PD----AR---LR------------------------RIVAAM--KR----RG--M------DW----GGD-W------------------------------S-R-FP-----DYP----HFELY----------------------------------------------------------------------------------------------------------------------------------------------------------------- 344
 345 --LLRRANQKLSVPGMHPSVVRIARDAIRELYPH---GI-KLGIAQS-FRSIAEQNALYAKG-R---TT---------------P--------------G-P-IVTQARGG--QSNHN---------------F--GVAIDVFL--Y----Q------DG-----ALFLSP-----PD----AR---LR------------------------RIVAAM--KR----RG--M------DW----GGD-W------------------------------S-R-FP-----DYP----HFELYDHVS------------------------------------------------------------------------------------------------------------------------------------------------------------- 345
 346 ------------------------------------------------HRSNEEQNDLYAQG-R---TK---------------P--------------G-K-IVTNAKAG--QSPHN---------------FLPARAFDIAFV-K------------PGN---LLDWNP------------EL--FK------------------------KFATLLANKR----ND--V------RW----GGT-F------------------------------T-S-FK-----DYP----HFELKD---------------------------------------------------------------------------------------------------------------------------------------------------------------- 346
 347 --AELVAKAEKKVGGLKPDVKKAVLSAVKEAYDR--YGI-GIIVSQG-YRSIAEQNGLYAQG-R---TK---------------P--------------G-N-IVTNAKGG--QSNHN---------------F--GVAVDFAID-L----I------DDGK--IDS-WQP-----SA----T-------------------------------IVNMM--KR----RG--F------KW----GGD-W------------------------------K-S-FT-----DLP----HFEACDWYRGERKYKVDTSEWKKKENINIVIKDVGYFQDKPQFLNSKSVRQWKHGTKVKLTKHNSHWYTGVVKDGNKSVRGYIYHSMAKVTSKNSDGSVNATINAHAFCWDNKKLNGGDFINLKRGFKGITHPASDGFY--------------------------- 347
 348 -------------------------------------------ITEC-YRSPERQNELYAQG-R---TR---------------P--------------G-L-IVTYKRGS--ESKHN---------------LSPTPALDVAFL-L----A-------DGS----VSWSG-----LL------LSKFA------------------------RLMKAA--DA-----R--V------VW----GGD-W------------------------------A-G-FK-----DRP----HFEV------------------------------------------------------------------------------------------------------------------------------------------------------------------ 348
 349 -------------------------------------------VTEG-YRSAAEQDALYAQG-R---TK---------------P--------------G-R-IVTYKQGG--ASKHN---------------RQPAEALDVAFM-L----S-------NGQ----VSWSA-----EL------LRRFA------------------------QLMKQA--NP-----A--I------RW----GGD-W------------------------------P-Q-FR-----DRP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 349
 350 --------------TLHPKARHTFFCFVNKCEEVDR----EYVVLSG-LRGPAEQDELYCHG-R-------------------ATEAYCVNLGFTAHPTGWR---TNAKRW--RSNHN---------------Y--GVAIDMQDF--------------------------------------NADDWV-----------------NQGIPSQMAGTVG--DQ----FG--L------EW----GGR-W--------------------------------TDSR-----DYP----HFQLS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 350
 351 -------------------------------ERMKARGF-PMVLLEG-YRSAERQNKLAGGS-T---------------------------------------KVTQAKGG--ESKHQ---------------Y--GLAADLAPV-------------RSGK----VVISE-------------RDPWA-------------------MQAYNALGEEA--QA----AG--L------TW----GGV-W------------------------------S---FR-----DYG----HIE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 351
 352 -------------------------------EKMKARGF-PMVLLEG-YRSAERQNKLAGGS-V---------------------------------------KVTQAKGG--ESKHQ---------------Y--GLAADLAPV-------------RNGK----VVISE-------------RDPWA-------------------MQAYNALGEEA--QA----AG--L------TW----GGV-W------------------------------S---FR-----DYG----HIE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 352
 353 -----------------------------VMEKMKARGF-PMVLLEG-YRSAERQNKLAGGS-V---------------------------------------KVTQAKGG--ESKHQ---------------Y--GLAADLAPV-------------RNGK----VVISE-------------RDPWA-------------------MQAYNALGEEA--QA----AG--L------TW----GGV-W------------------------------S---FR-----DYG----HIE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 353
 354 --------LNRADRDWNKLDAAFVQTVLRVMARLEARGF-PMTLLEG-YRSPERQDALAGQG-T---------------------------------------LVTKAKGG--QSKHQ---------------C--GLAVDLAPV-------------RNGK----VVVSE-------------RAPWA-------------------MSAYLALGEEA--TA----AG--L------TW----GGN-W------------------------------S---FK-----DYG----HIE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 354
 355 ------------------LDAAFVQTVLRVMARLEARGF-PMTLLEG-YRSPERQDALAGQG-T---------------------------------------LVTKAKGG--QSKHQ---------------Y--GLAVDLAPV-------------RNGK----VVVSE-------------RAPWA-------------------MSAYLALGEEA--TA----AG--L------TW----GGT-W------------------------------S---FK-----DYG----HIE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 355
 356 -----------------------------LFERMQSRQY-PLALLEG-YRSPERQDMLASKG-L---------------------------------------HVTHARAF--QSKHQ---------------Y--GLAADVAPI-------------RNGK----LVISE-------------RDPWA-------------------AAAYKVLGEEA--AA----LG--L------VW----GGN-W------------------------------A---MN-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 356
 357 ------------------LDARFRERLQRVVERLRGRGQ-HFVLVEG-YRSPERQDQLFALP-T---------------------------------------KVTAARAW--ESRHQ---------------Y--GLAADLAPV-------------RDGA----ASF-E-------------TDGLG-------------------MEAYRLLGEEA--EA----AG--L------TW----GGR-W------------------------------D---IR-----DYG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 357
 358 -------------------------------------GY-EMTLIEG-YRSPERQAVLALQG-S---------------------------------------QVTRAGAN--MSYHQ---------------Y--GLAADSAFV-------------RDGR----VVISE-------------RDPWV-------------------MHGYELYGALA--ET----YG--L------TW----GGR-W------------------------------S---FR-----DLG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 358
 359 -------------------------------------GY-DMVLIEG-YRSPERQARLYEQG-A---------------------------------------HVTQVGAN--MSYHQ---------------H--GLAADSAFY-------------RDGK----VVISE-------------RDPWA-------------------MRGYQLYGEVA--EQ----VG--L------TW----GGR-W------------------------------K---MQ-----DYG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 359
 360 ---------------------------------AERYGY-QMVLLEG-YRSPDRQASLASSG-N---------------------------------------QVTQAGAN--RSYHQ---------------Y--GLAADNAFL-------------RDGK----VVISE-------------KDPWA-------------------MRGYALYGKTA--AE----VG--L------VW----GGD-W------------------------------S---FH-----DYG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 360
 361 ----------------------------AFKLMREQHGY-EMVLLEG-YRSPERQAQLASLG-P---------------------------------------AVTHAGAG--QSYHQ---------------Y--GLAADCAFM-------------RDGR----IVISE-------------RDAWA-------------------ARGYEHFGAVA--EA----VG--L------SW----GGA-W------------------------------R-T-LV-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 361
 362 -----------------------------------EHGY-EMALLEG-YRSPERQVKLAAMG-S---------------------------------------NVTQATAF--QSYHQ---------------Y--GLAADNAFF-------------RDGK----LVISE-------------KDPWA-------------------MRGYELYGQTA--ES----VG--L------VW----GGR-W------------------------------K---MM-----DLG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 362
 363 -------------------------------------GY-EMALLEG-YRSPERQVKLAAMG-S---------------------------------------NVTQATAF--QSYHQ---------------Y--GLAADNAFF-------------RDGK----LVISE-------------KDPWA-------------------MRGYELYGQTA--ES----VG--L------VW----GGR-W------------------------------K---MM-----DLG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 363
 364 -------------------------------------GY-EMALLEG-YRSPERQVKLAAMG-S---------------------------------------NVTQATAF--QSYHQ---------------Y--GLAADNAFF-------------RDGK----LVISE-------------KDPWA-------------------MRGYELYGQTA--ES----VG--L------VW----GGR-W------------------------------K---MM-----DLG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 364
 365 -----------------------------------EHGY-EMALLEG-YRSPERQVKLAAMG-S---------------------------------------NVTQATAF--QSYHQ---------------Y--GLAADSAFF-------------RDGK----LVISE-------------KDPWA-------------------MRGYELYGQTA--ES----VG--L------VW----GGR-W------------------------------K---MM-----DLG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 365
 366 -----------------LDADFRQRLLLVYKIMRDEHGY-EMALLEG-YRSPERQEKLAAMG-S---------------------------------------NVTQATAF--QSYHQ---------------Y--GLAADSAFF-------------RDGK----LVISE-------------KDPWA-------------------MRGYALYGQAA--ES----VG--L------VW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 366
 367 -----------------------------------EHGY-EMALLEG-FRSPDRQAKLAAMG-S---------------------------------------NVTQAGAY--QSYHQ---------------Y--GLAADSAFF-------------REGK----LVISE-------------KDPWA-------------------MRGYELYGQTA--ES----VG--L------VW----GGR-W------------------------------K---MM-----DLG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 367
 368 -----------------------------------EHGY-EMALLEG-FRSPDRQAKLAAMG-S---------------------------------------NVTQAGAY--QSYHQ---------------Y--GLAADSAFF-------------RDGK----LVISE-------------KDPWA-------------------MRGYELYGQTA--ES----VG--L------VW----GGR-W------------------------------K---MM-----DLG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 368
 369 -----------------------------------QYGY-EMALLEG-YRSPERQNRLAQMG-G---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQTA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 369
 370 -------------------------------------GY-EMALLEG-YRSPERQNRLAQMG-G---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQTA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 370
 371 -----------------LDADFRTRLLLVYKIMREQYGY-EMALLEG-YRSPERQNRLAQMG-G---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLASDNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQTA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 371
 372 -----------------------------------QYGY-EMALLEG-YRSPERQNRLAQIG-S---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQTA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 372
 373 -------------------------------------GY-EMALLEG-YRSPERQNRLAQIG-S---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQTA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 373
 374 -----------------LDADFRTRLLLVYKIMHEQYGY-EMALLEG-YRSPERQNRLAQIG-S---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQTA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 374
 375 -----------------LDADFRTRLLLVYKIMHEQYGY-EMALLEG-YRSPERQNRLAQIG-S---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQTA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 375
 376 ----------------------------------EQHGY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------F--GLASDNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQTA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 376
 377 -------------------------------------GY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------SVTNAAAF--QSYHQ---------------F--GLASDNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQTA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 377
 378 -------------------------------------GY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EE----VG--L------TW----GGR-W------------------------------K---LM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 378
 379 -------------------------------------GY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EE----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 379
 380 -------------------------------------GY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EE----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 380
 381 -----------------LDTDFRTRLLLVYKIMREQHGY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EE----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 381
 382 -------------------------------------GY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EE----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 382
 383 -----------------------------------QHGY-EMALLEG-YRSPERQNRLAQMG-G---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EE----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 383
 384 -----------------------------------QHGY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAADNAFL-------------RDGK----IVISE-------------KDPWA-------------------MQGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 384
 385 -----------------------------------QYGY-EMALLEG-YRSPERQNRLAAMG-G---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 385
 386 -----------------------------------QYGY-EMALLEG-YRSPERQNRLAAMG-G---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 386
 387 -----------------------------------QYGY-EMALLEG-YRSPERQNRLAQMG-G---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 387
 388 -----------------------------------QYGY-EMALLEG-YRSPERQNRLAQMG-G---------------------------------------SVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 388
 389 -------------------------------------GY-EMALLEG-YRSPERQNRLAQMG-G---------------------------------------SVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 389
 390 -------------------------------------GY-EMALLEG-YRSPERQNRLAQMG-G---------------------------------------SVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 390
 391 -----------------------------------QYGY-EMALLEG-YRSPERQNRLAQMG-T---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 391
 392 ----------------------------------EQHGY-EMALLEG-YRSPERQNRLAQMG-T---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 392
 393 -----------------------------------QYGY-EMALLEG-YRSPERQNRLAQMG-T---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 393
 394 -----------------------------------QYGY-EMALLEG-YRSPERQNRLAQMG-T---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 394
 395 -----------------------------------QYGY-EMALLEG-YRSPERQNRLAQMG-T---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 395
 396 -----------------LDPDFRTRLLLVYKIMHEQYGY-EMALLEG-YRSPERQNRLAQMG-T---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 396
 397 -----------------LDPDFRTRLLLVYKIMHEQYGY-EMALLEG-YRSPERQNRLAQMG-T---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 397
 398 -----------------LDPDFRTRLLLVYKIMHEQYGY-EMALLEG-YRSPERQNRLAQMG-T---------------------------------------NVTNAAAY--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 398
 399 ----------------------------------EQHGY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 399
 400 ----------------------------------EQHGY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 400
 401 -----------------------------------QYGY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 401
 402 -----------------------------------QYGY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 402
 403 -------------------------------------GY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 403
 404 -----------------LDPDFRTRLLLVYKIMHEQYGY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 404
 405 -----------------LDPDFRTRLLLVYKIMHEQHGY-EMALLEG-YRSPERQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 405
 406 -----------------------------------QYGY-EMALLEG-YRSPDRQNRLAQMG-S---------------------------------------NVTNAAAF--QSYHQ---------------F--GLAADNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 406
 407 -----------------------------------QYGY-EMALLEG-YRSPERQNRLAAIG-S---------------------------------------NVTNAAAY--QSYHQ---------------F--GLASDNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 407
 408 -----------------LDPDFRTRLLLVYKIMHEQYGY-EMALLEG-YRSPERQNRLAAIG-S---------------------------------------NVTNAAAY--QSYHQ---------------F--GLASDNAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EQ----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 408
 409 -----------------------------------EHGY-EMALLEG-YRSPERQARLAAMG-T---------------------------------------HVTKAGAY--HSYHQ---------------F--GLAADSAFY-------------RDGK----LVISE-------------KDPWA-------------------MRGYELYGQIA--ES----AG--L------TW----GGR-W------------------------------K---MM-----DLG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 409
 410 -----------------------------------EHGY-EMALLEG-YRSPERQAKLAAMG-S---------------------------------------HVTQAGAY--HSYHQ---------------F--GLAADSAFY-------------RDGK----LVISE-------------KDPWA-------------------MRGYELYGRAA--ES----AG--L------VW----GGR-W------------------------------K---MM-----DLG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 410
 411 -----------------------------------KHGY-EMALIEG-YRSPERQNMLAGMG-G---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAGDCAFV-------------RNGK----LVISE-------------KDPWA-------------------MEGYRLYGEVA--ES----VG--L------TW----GGR-W------------------------------K---LM-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 411
 412 -----------------LNPEYAQRLLLVFKIMKEKYGI-EMALIEG-YRSPERQNMLAGMG-G---------------------------------------NVTNAAAF--QSYHQ---------------Y--GLAGDCAFV-------------RNGK----LVISE-------------KDPWA-------------------MEAYRHYGEVA--ES----VG--L------TW----GGR-W------------------------------K---LM-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 412
 413 -----------------LNPEYAQRLLLVFKIMKEKHGY-EMALIEG-YRSPQRQNMLAGMG-G---------------------------------------GITNAAAF--QSYHQ---------------Y--GLAGDCAFV-------------RNGK----LVISE-------------KDPWA-------------------MAGYRLYGEVA--ES----VG--L------TW----GGR-W------------------------------K---LM-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 413
 414 ----------------------------------ERHGY-EMVLIEG-YRSPERQNMLAGFG-S---------------------------------------SVTNAAAF--QSYHQ---------------Y--GLAGDCAFV-------------RNGK----LVISE-------------KDPWA-------------------MEGYRLYGEVA--GS----VG--L------TW----GGN-W------------------------------K---MM-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 414
 415 ----------------------------------EKHGY-EMALIEG-YRSPERQDLLAKMG-S---------------------------------------NVTNAGAF--QSYHQ---------------Y--GLAADCAFV-------------RNGK----LVISE-------------KDPWA-------------------MEGYRLYGEVA--ES----VG--L------TW----GGR-W------------------------------K---MM-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 415
 416 ----------------------------------EKHGY-DMAILEG-YRSPERQNMLAGMG-S---------------------------------------NVTNAAAF--QSWHQ---------------Y--GLAADCAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGEVA--ES----VG--M------TW----GGR-W------------------------------K---MM-----DFG----HTEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 416
 417 ----------------------------------EKHGY-DMAILEG-YRSPERQNMLAGMG-S---------------------------------------NVTNAAAF--QSWHQ---------------Y--GLAADCAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGEVA--ES----VG--M------TW----GGR-W------------------------------K---MM-----DFG----HTEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 417
 418 ----------------------------------EKHGY-DMAILEG-YRSPERQNLLASMG-S---------------------------------------NVTNAAAF--QSWHQ---------------Y--GLAADCAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGEVA--ES----VG--M------TW----GGR-W------------------------------K---MM-----DFG----HTEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 418
 419 ---------------------------------KEKHGY-DMAILEG-YRSPERQNALAAMG-P---------------------------------------NVTNAAAF--QSWHQ---------------Y--GLAADCAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGEVA--ES----LG--L------TW----GGR-W------------------------------K---MM-----DFG----HTEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 419
 420 -----------------------------------KYGY-EMALLEG-YRSPARQDMLAGMG-S---------------------------------------QVTNARAF--QSWHQ---------------Y--GLAADCAFW-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------T---MM-----DFG----HTEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 420
 421 ----------------------------------EQHGY-DMVIIEG-YRSPERQNALAQMG-G---------------------------------------SVTNAKAF--QSYHQ---------------Y--GLAADSAFM-------------RNGK----LVITE-------------KDPWA-------------------MRGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 421
 422 -----------------LDADFTQRLLMTFKIMKEKYGY-DMVIIEG-YRSPERQNALAQMG-G---------------------------------------SVTNAKAF--QSYHQ---------------Y--GLAADSAFM-------------RSGK----LVITE-------------KDPWA-------------------MRGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------K---MM-----DLG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 422
 423 -----------------------------------RYGY-DMALIEG-YRSPQRQAMLAAKG-G---------------------------------------SVTNAGAW--QSYHQ---------------Y--GLAADCAFY-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--EA----AG--L------VW----GGS-W------------------------------K---MM-----DLG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 423
 424 ------------------------------------HGY-EMVLLEG-YRSPARQDQLAAAG-P---------------------------------------NVTNARAF--QSYHQ---------------Y--GLAADCAFM-------------HEGK----LIISE-------------KNAWA-------------------MRGYRLYGVTA--ES----VG--L------RW----GGR-W------------------------------T---MM-----DFG----HTELP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 424
 425 ------------------------------------HGY-DMVLLEG-YRSPARQDQLAAAG-P---------------------------------------NVTNARAF--QSYHQ---------------Y--GLAADCAFM-------------HEGK----LIISE-------------KNAWA-------------------MRGYRLYGVTA--ES----VG--L------RW----GGR-W------------------------------T---MM-----DFG----HTELP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 425
 426 --------------------------------MKENHGY-DMAILEG-YRSPERQNALAAAG-P---------------------------------------AVTNAKAF--QSYHQ---------------F--GLAADCAFL-------------RDGK----LLISE-------------RDPWA-------------------MRGYRLYGEAA--ES----VG--L------HW----GGR-W------------------------------T---MM-----DFG----HTEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 426
 427 ----------------------------------EQHGY-EMALLEG-YRSPARQDELAATG-G---------------------------------------HVTNARAF--QSWHQ---------------Y--GLAADCAFL-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--ES----LG--L------TW----GGR-W------------------------------K---MM-----DFG----HIEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 427
 428 ----------------------------------ERHGY-EMAILEG-YRSPARQDALAALG-P---------------------------------------GVTNARSW--QSWHQ---------------Y--GLAADCAFV-------------RDGK----LVISE-------------KDPWA-------------------MRGYQLYGQVA--ES----VG--L------TW----GGR-W------------------------------K---MM-----DFG----HTEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 428
 429 ---------------------------------REEHGY-EMVLIEG-YRSPERQTQLAGMG-S---------------------------------------HVTNAGAY--QSYHQ---------------Y--GLAADSAFL-------------RDGK----VVVSE-------------KDPWA-------------------MRGYELFGETA--ER----VG--L------TW----GGR-W------------------------------K---MM-----DFG----HTEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 429
 430 ----------------------------AYRVMREEHGY-EMVLIEG-YRSPERQEELASKG-S---------------------------------------HVTNAGAY--QSYHQ---------------Y--GLAADSAFL-------------RDGK----VVVSE-------------KDPWA-------------------MRGYELFGETA--ER----VG--L------TW----GGR-W------------------------------K---LM-----DFG----HTEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 430
 431 ----------------------------AYRVMREEHGY-EMVLIEG-YRSPDRQAELAKMG-S---------------------------------------HVTNAGAY--QSYHQ---------------F--GLAADSAFL-------------RDGK----VVVSE-------------KDPWA-------------------MRGYELFGETA--ER----VG--L------TW----GGR-W------------------------------K---MM-----DFG----HTEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 431
 432 ----------------------------------EQHGY-EMALIEG-YRSPERQEELAGMG-T---------------------------------------HVTNAGAF--QSYHQ---------------Y--GLAADSAFY-------------RDGK----IVISE-------------KDPWA-------------------MRGYELFGETA--EL----VG--L------TW----GGR-W------------------------------K---MM-----DFG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 432
 433 -------------------------------------GY-EMALIEG-YRSPERQEELAGMG-S---------------------------------------HVTNAGAF--QSYHQ---------------F--GLAADSAFY-------------RDGK----IVISE-------------KDPWA-------------------MRGYELFGQTA--EL----VG--L------TW----GGR-W------------------------------K---MM-----DFG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 433
 434 -----------------LDADFRNRLLLVYKIMKEKHGY-DLALLEG-YRSPERQAKLAALG-N---------------------------------------TVTLAKAN--QSYHQ---------------Y--GLAADNAFY-------------RNGK----LVISE-------------RDPWA-------------------MEGYRLYGEVA--ES----VG--L------VW----GGR-W------------------------------S-S-IK-----DYG----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 434
 435 ----------------------------------EQYGY-ELVLLEG-YRSPVRQNMLAG-N-P---------------------------------------NTTKAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 435
 436 ----------------------------------EQYGY-ELVLLEG-YRSPVRQNMLAG-N-P---------------------------------------NTTKAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 436
 437 -----------------MNPRYKQRLLMVFKIMKEQYGY-ELVLLEG-YRSPVRQNMLAG-N-P---------------------------------------NTTKAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 437
 438 ----------------------------------EQYGY-ELVLLEG-YRSPGRQNMLAG-N-P---------------------------------------NTTKAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 438
 439 -----------------------------------QYGY-ELVLLEG-YRSPGRQNMLAG-N-P---------------------------------------NTTKAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 439
 440 ---------------------------MVFKIMKEQYGY-ELVLLEG-YRSPGRQNMLAG-N-P---------------------------------------NTTKAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 440
 441 ---------------------------MVFKIMKEQYGY-ELVLLEG-YRSPTRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 441
 442 ---------------------------MVFKIMKEQYGY-ELVLLEG-YRSPARQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 442
 443 ----------------------------------EQYGY-ELVLLEG-YRSPVRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 443
 444 ----------------------------------EQYGY-ELVLLEG-YRSPVRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 444
 445 -----------------------------------QHGY-ELVLLEG-YRSPNRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 445
 446 -----------------------------------QHGY-ELVLLEG-YRSPNRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 446
 447 ----------------------------------EQHGY-ELVLLEG-YRSPNRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 447
 448 -----------------------------------QHGY-ELVLLEG-YRSPNRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 448
 449 -----------------------------------QHGY-ELVLLEG-YRSPNRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 449
 450 -----------------------------------QHGY-ELVLLEG-YRSPSRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 450
 451 -----------------------------------QHGY-ELVLLEG-YRSPSRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 451
 452 -----------------------------------QHGY-ELVLLEG-YRSPSRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 452
 453 -----------------------------------QHGY-ELVLLEG-YRSPSRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 453
 454 ------------------------------------YGY-ELVLLEG-YRSPARQNMLAG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 454
 455 -----------------------------------QYGY-ELVLLEG-YRSPARQNMLAG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 455
 456 ------------------------------------YGY-ELVLLEG-YRSPARQNMLAG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 456
 457 ------------------------------------YGY-ELVLLEG-YRSPARQNMLAG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 457
 458 ------------------------------------YGY-ELVLLEG-YRSPARQNMLAG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 458
 459 ------------------------------------YGY-ELVLLEG-YRSPARQNMLAG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 459
 460 ------------------------------------YGY-ELVLLEG-YRSPARQNMLAG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 460
 461 ---------------------------MVFKIMKEQYGY-ELVLLEG-YRSPARQNMLAG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 461
 462 -----------------------------------QYGY-ELVLLEG-YRSPARQNMLAG-N-P---------------------------------------NTTKARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MQGYRLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 462
 463 ----------------------------------EQHGY-ELVLLEG-YRSPSRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 463
 464 ----------------------------------EQHGY-ELVLLEG-YRSPSRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 464
 465 ----------------------------------EQHGY-ELVLLEG-YRSPSRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 465
 466 -----------------------------------QHGY-ELVLLEG-YRSPSRQNMLAG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 466
 467 -----------------------------------QHGY-ELVLLEG-YRSPSRQNMLAG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 467
 468 --------------------------------MKEQHDY-ELVLLEG-YRSPSRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 468
 469 ----------------------------------EQHGY-ELVLLEG-YRSPSRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 469
 470 -----------------------------------QHGY-ELVLLEG-YRSPNRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 470
 471 ----------------------------------EQHGY-ELVLLEG-YRSPNRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 471
 472 -----------------------------------QHGY-ELVLLEG-YRSPNRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 472
 473 -----------------------------------QHGY-ELVLLEG-YRSPNRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 473
 474 ----------------------------------EQHGY-ELVLLEG-YRSPNRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 474
 475 ----------------------------------EQHGY-ELVLLEG-YRSPNRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 475
 476 -----------------------------------QHGY-ELVLLEG-YRSPNRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 476
 477 -----------------------------------QHGY-ELVLLEG-YRSPNRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 477
 478 -----------------------------------QHGY-ELVLLEG-YRSPNRQNLLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 478
 479 ----------------------------------EQYGY-ELVLLEG-YRSPERQNMLAG-N-P---------------------------------------NTTRARSY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 479
 480 ----------------------------------EQYGY-ELVLLEG-YRSPERQNMLAG-N-P---------------------------------------NTTRARSY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 480
 481 -----------------------------------QHGY-DLVLLEG-YRSPSRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFR-------------RNGK----IVITE-------------RDPWA-------------------MRGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 481
 482 -------------------------------------GY-DLVLLEG-YRSPSRQNMLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFR-------------RNGK----IVITE-------------RDPWA-------------------MRGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 482
 483 -----------------------------------RHGY-ELVLLEG-YRSPERQNFLSG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 483
 484 -----------------MNPRYKQRLLMVFKIMKERYGY-ELVLLEG-YRSPERQNLLSG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 484
 485 ------------------------------------YGY-ELVLLEG-YRSPARQNLLSG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 485
 486 ------------------------------------YGY-ELVLLEG-YRSPARQNLLSG-N-P---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVITE-------------RDPWA-------------------MRGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 486
 487 -----------------------------FKVMKEQHNY-ELVLLEG-YRSPSRQNLLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQIYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 487
 488 ---------------------------------KEQHNY-ELVLLEG-YRSPSRQNLLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQIYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 488
 489 ---------------------------------KEQHNY-ELVLLEG-YRSPSRQNLLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQIYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 489
 490 ----------------------------------------ELVLLEG-YRSPSRQNLLAG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQIYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 490
 491 -----------------------------------QHGY-ELVLLEG-YRSPSRQNMLST-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADIAFK-------------RNGK----IVISE-------------RDPWA-------------------MRGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 491
 492 ----------------------------------EQHGY-ELVLLEG-YRSPERQNSLSA-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADIAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 492
 493 ----------------------------------EQHGY-ELVLLEG-YRSPERQNSLSA-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADIAFK-------------RNGK----VLISE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 493
 494 ----------------------------------EQHGY-ELVLLEG-YRSPERQNSLSA-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADIAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 494
 495 ----------------------------------EQHGY-ELVLLEG-YRSPERQNSLSA-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 495
 496 -----------------------------------RHGY-ELVLLEG-YRSPERQNSLSK-N-K---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 496
 497 ----------------------------------ERHGY-ELVLLEG-YRSPERQNSLSK-N-K---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 497
 498 -----------------------------------RHGY-ELVLLEG-YRSPERQNSLSK-N-K---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADVAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 498
 499 ------------------------------------YGY-DLVLLEG-YRSPERQNLLSG-N-P---------------------------------------NTTRAKGY--QSYHQ---------------F--GLAADIAFQ-------------RNGK----VVISE-------------RDPWA-------------------MRGYELYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 499
 500 -------------------------------------GY-ELVLLEG-YRSPQRQNSLAS-N-K---------------------------------------NTTLARGY--QSYHQ---------------F--GLAADVAFK-------------RDGK----VVISE-------------RDPWA-------------------MRGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTEYRMPN-------------------------------------------------------------------------------------------------------------------------------------------------------------- 500
 501 -------------------------------------GY-ELVLLEG-YRSPQRQNSLAS-N-K---------------------------------------NTTLARGY--QSYHQ---------------F--GLAADVAFK-------------RDGK----VVISE-------------RDPWA-------------------MRGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTEFRMPN-------------------------------------------------------------------------------------------------------------------------------------------------------------- 501
 502 -----------------------------------QHGY-DMVLLEG-YRSPDRQNSLAL-N-I---------------------------------------NTTRARGY--QSYHQ---------------F--GLAADAAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYQLYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 502
 503 -----------------------------------RYGY-ELVLLEG-YRSPARQNMLSG-N-K---------------------------------------NTTRAKAF--QSYHQ---------------F--GLAADVAFK-------------RDGK----VVISE-------------RDPWA-------------------WKGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IH-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 503
 504 -----------------------------FKIMKERYNY-EMVLLEG-YRSPARQNMLSS-N-I---------------------------------------NTTRAKAF--QSYHQ---------------F--GLASDIAFK-------------REGK----VVISE-------------RDPWA-------------------WRGYQLYGEVA--ES----VG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 504
 505 ----------------------------------EQHGY-ELVLLEG-YRSPERQNSLAT-N-S---------------------------------------NITKAKGF--QSYHQ---------------F--GLAADIAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELFGQIA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 505
 506 ----------------------------------EQHGY-ELVLLEG-YRSPERQNSLAT-N-S---------------------------------------NITKAKGF--QSYHQ---------------F--GLAADIAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELFGQIA--ES----MG--L------TW----GGR-W------------------------------K-S-IK-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 506
 507 -----------------------------------QHGY-ELVLLEG-YRSPERQNSLAT-N-S---------------------------------------NITKAKGF--QSYHQ---------------F--GLAADIAFK-------------RNGK----VVISE-------------RDPCA-------------------MRGYELFGQIA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 507
 508 ----------------------------------EQHGY-ELVLLEG-YRSPERQNSLAS-N-S---------------------------------------NITKAKGF--QSYHQ---------------F--GLAADIAFK-------------RNGK----VVISE-------------RDPWA-------------------MRGYELFGQIA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 508
 509 -----------------------------------QYGY-ELVLLEG-YRSPERQNSLAT-N-R---------------------------------------NITQAKGF--QSYHQ---------------F--GLAADIAFK-------------RHGK----VVISE-------------RDPWA-------------------MRGYQLYGQIA--ES----VG--L------TW----GGR-W------------------------------K-T-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 509
 510 ------------------------------KIMKEQHDY-ELVLLEG-YRSPERQNSLAA-D-S---------------------------------------NITKAKGF--QSYHQ---------------F--GLAADIAFK-------------RHGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 510
 511 ------------------------------KIMKEQHDY-ELVLLEG-YRSPKRQNSLAA-D-S---------------------------------------NITKAKGF--QSYHQ---------------F--GLAADIAFK-------------RHGK----VVITE-------------RDPWA-------------------MRGYELYGQVA--ES----VG--L------TW----GGR-W------------------------------K-S-IK-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 511
 512 ----------------------------------ERHGY-EMVLLEG-YRSPEQQNLLAG-N-R---------------------------------------HVTRAKGF--QSYHQ---------------F--GLAADIAFK-------------RNGK----VVISE-------------RNPEV-------------------MKGYQLYGEVA--ES----LG--L------TW----GGR-W------------------------------K-S-IQ-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 512
 513 ------------------------------KIMKERHGY-EMVLLEG-YRSPERQTRLSG-N-T---------------------------------------ATTLAKAY--QSYHQ---------------F--GLAADVAFK-------------RDGK----VVISE-------------RDPWA-------------------WKGYQLYGVVA--ES----VG--L------TW----GGR-W------------------------------T-R-IH-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 513
 514 --------------------------------MKERHGY-EMVLLEG-YRSPERQTRLSG-N-T---------------------------------------ATTLAKAY--QSYHQ---------------F--GLAADVAFK-------------RDGK----VVISE-------------RDPWA-------------------WKGYQLYGVVA--ES----VG--L------TW----GGR-W------------------------------T-R-IH-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 514
 515 ------------------------------KIMKERHGY-EMVLLEG-YRSPERQTRLSG-N-T---------------------------------------ATTLAKAY--QSYHQ---------------F--GLAADVAFK-------------RDGK----VVISE-------------RDPWA-------------------WKGYQLYGVVA--ES----VG--L------TW----GGR-W------------------------------T-R-IH-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 515
 516 ------------------------------KIMKERHGY-EMVLLEG-YRSPERQTRLSG-N-T---------------------------------------ATTLAKAY--QSYHQ---------------F--GLAADVAFK-------------RDGK----VVISE-------------RDPWA-------------------WKGYQLYGVVA--ES----VG--L------TW----GGR-W------------------------------T-R-IH-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 516
 517 --------------------------------MKERHGY-EMVLLEG-YRSPERQTRLSG-N-T---------------------------------------ATTLAKAY--QSYHQ---------------F--GLAADVAFK-------------RDGK----VVISE-------------RDPWA-------------------WKGYQLYGVVA--ES----VG--L------TW----GGR-W------------------------------T-R-IH-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 517
 518 ------------------------------KIMKERHGY-EMVLLEG-YRSPERQTRLSG-N-T---------------------------------------ATTLAKAY--QSYHQ---------------F--GLAADVAFK-------------RDGK----VVISE-------------RDPWA-------------------WKGYQLYGVVA--ES----VG--L------TW----GGR-W------------------------------T-R-IH-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 518
 519 ------------------------------KIMKERHGY-EMVLLEG-YRSPERQTRLSG-N-T---------------------------------------ATTLAKAY--QSYHQ---------------F--GLAADVAFK-------------RDGK----VVISE-------------RDPWA-------------------WKGYQLYGVVA--ES----VG--L------TW----GGR-W------------------------------T-R-IH-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 519
 520 -------------------------------IMKEQHGY-ELVLLEG-YRSPARQNSLSR-N-K---------------------------------------ATTLATAY--RSYHQ---------------F--GLAADVAFK-------------RDGK----VVISE-------------RDPWA-------------------MRGYQLYGQVA--ES----VG--L------VW----GGR-W------------------------------T-K-IH-----DYG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 520
 521 -----------------------------FKIMKEKYDY-EMVLLEG-YRNPQRQNMLSA-N-T---------------------------------------HTTHARAF--QSYHQ---------------F--GLAADIAFI-------------HEGK----VVISE-------------RDPWA-------------------MRGYQLYGEVA--ES----VG--L------VW----GGH-W------------------------------K-S-IK-----DFG----HTE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 521
 522 ----------------------------VYKVMSDQYGY-DMVLLEG-YRSPARQARLLKKG-T---------------------------------------HVTKAGSY--KSYHQ---------------F--GLAGDSAFI-------------RNGK----IVISE-------------KDPWA-------------------MRGYKLYGKVA--KS----AG--L------VW----GGD-W------------------------------R---MM-----DLG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 522
 523 ------------------------------KVMSDQYGY-DMVLLEG-YRSPARQARLLKKG-T---------------------------------------HVTKAGSY--KSYHQ---------------F--GLAGDSAFI-------------RNGK----IVISE-------------KDPWA-------------------MRGYKLYGKVA--KS----AG--L------VW----GGD-W------------------------------R---MM-----DLG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 523
 524 -----------------------------YKVMSDQYGY-DMVLLEG-YRSPARQARLLKKG-T---------------------------------------HVTKAGSY--KSYHQ---------------F--GLAADSAFI-------------RSGK----IVITE-------------KDPWA-------------------MRGYKLYGKVA--KS----AG--L------VW----GGD-W------------------------------R---MM-----DLG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 524
 525 -----------------------------------VHGY-DMVLLEG-YRSPFRQQLLATRG-S---------------------------------------GVTGAAAF--QSYHQ---------------Y--GLAADCAFL-------------RHGQ----LLMSE-------------KDPWT-------------------MRGYRLYGGLA--EA----AG--L------QW----GGR-W------------------------------S---IR-----DFG----HIEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 525
 526 ----------------------------------EQHGY-EMVLVEG-YRSPGRQAALARQG-G---------------------------------------SVTRAGAG--QSCHQ---------------Y--GVAVDAALY-------------RDGR----LHWDM-------------GDAWT-------------------RRGYALYGELA--VQ----AG--L------EW----GGS-W------------------------------R-N-LK-----DYV----HLEMK----------------------------------------------------------------------------------------------------------------------------------------------------------------- 526
 527 -----------------------------------VHGY-EMVLVEG-YRSPERQAALAAKG-G---------------------------------------AVTRAGAG--QSCHQ---------------Y--GLAVDSALY-------------RDGR----LQWDM-------------EDPWT-------------------RRGYFLYGELA--VE----AG--L------EW----GGN-W------------------------------R-S-IK-----DYV----HLELK----------------------------------------------------------------------------------------------------------------------------------------------------------------- 527
 528 ---------------------------------EEQYGY-RMVLVEG-FRSAQRQAELAAKG-A---------------------------------------GVTRAGAG--QSCHQ---------------Y--GMAVDSALY-------------RDGK----LQWDM-------------RDPWV-------------------RRGYFLYGELA--QQ----VG--L------EW----GGS-W------------------------------R-S-IK-----DYV----HLE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 528
 529 -------------------------VLAIYEVMRRQYGY-EMVLVEG-YRSPERQAELMS-G-G---------------------------------------KATRAGAW--QSCHQ---------------Y--GLGVDSAPI-------------RDGK----LQWDM-------------GDPWT-------------------RRGYFLYGELA--EQ----AG--L------EW----GGN-W------------------------------R-S-IK-----DYV----HVEMS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 529
 530 ----------------------------------RQYGY-EMVLIEG-YRSPQRQAELMA-G-G---------------------------------------KATRAGAW--QSCHQ---------------Y--GLGVDSAPI-------------RDGK----LQWDM-------------NDEWT-------------------KRGYFLYGELA--EQ----AG--L------DW----GGN-W------------------------------R-S-IK-----DYV----HVEMT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 530
 531 -------------------------------------GY-EMVLIEG-YRSPQRQAELMA-G-G---------------------------------------KATRAGAW--QSCHQ---------------Y--GLGVDSAPI-------------RDGK----LQWDM-------------NDEWT-------------------KRGYFLYGELA--EQ----AG--L------DW----GGN-W------------------------------R-S-IK-----DYV----HVEM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 531
 532 ----------------------------------RQYGY-EMVLVEG-YRSPERQAELMG-G-G---------------------------------------RATRASAW--QSCHQ---------------Y--GLAVDSAPL-------------RDGK----LQWDM-------------GDPWT-------------------RRAYFLYGELA--QQ----AG--L------EW----GGS-W------------------------------R-S-IK-----DYV----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 532
 533 --------------------------------MRRQYGY-EMVLVEG-YRSPERQAELMG-G-G---------------------------------------RATRASAW--QSCHQ---------------Y--GLAVDSAPL-------------RDGK----LQWDM-------------GDPWT-------------------KRAYFLYGELA--QQ----AG--L------EW----GGS-W------------------------------R-S-IK-----DYV----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 533
 534 -------------------------------------GY-EMVLVEG-YRSPERQAELMG-G-G---------------------------------------RATRAGSW--QSCHQ---------------Y--GLAVDSAPL-------------RDGK----LQWDM-------------GDPWT-------------------RRAYFLYGELA--QQ----AG--L------EW----GGS-W------------------------------R-S-IK-----DYV----HLEKL----------------------------------------------------------------------------------------------------------------------------------------------------------------- 534
 535 --------------------------------MRRQYGY-EMVLVEG-YRSPERQAELMG-D-G---------------------------------------RATRAGAW--QSCHQ---------------Y--GLAVDSAPL-------------RDGK----LQWDM-------------GDPLT-------------------KRVYFLYGELA--QQ----AG--L------EW----GGS-W------------------------------R-S-IK-----DYV----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 535
 536 -----------------------RQSVLAIHQAMARQGY-RMVLVEG-YRSPERQAALARRG-S---------------------------------------GTTLAGAG--RSCHQ---------------Y--GLAVDSALY-------------RDGR----LQWDM-------------DDPWT-------------------RRGYLLYGRLA--VD----AG--L------EW----GGN-W------------------------------R-R-LR-----DYV----HVEMR----------------------------------------------------------------------------------------------------------------------------------------------------------------- 536
 537 ------------------------------RVMKQQYGV-EMVLVEG-FRDAERQKKLMGKG------------------------------------------ASLAGAW--RSCHQ---------------Y--GLAVDSAPL-------------KDGM----LQWDM-------------EDPWT-------------------RRAYFLYGELA--KE----AG--L------AW----GGD-W------------------------------T-N-LK-----DYV----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 537
 538 ------------------------------RVMKQQYGV-EMVLVEG-FRDAERQKKLMGKG------------------------------------------ASLAGAW--RSCHQ---------------Y--GLAVDSAPL-------------KDGM----LQWDM-------------EDPWT-------------------RRAYFLYGELA--KE----AG--L------TW----GGD-W------------------------------T-N-LK-----DYV----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 538
 539 -----------------------------------QHGY-EMALVEG-YRSPERQARLAAQG-G---------------------------------------SVTRAGAG--RSWHQ---------------Y--GLAADSAPV-------------RNGQ----LQWDM-------------EDPWT-------------------RRGYQLYGEVA--RS----VG--L------VW----GGG-W------------------------------T-S-IQ-----DYG----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 539
 540 ---------------SKLQPQFRRRLVALFEIAQERHGY-QVVLMEG-HRSAERQARLAALG-P---------------------------------------ATTLAGPD--RSRHQ---------------A--GLAADLAFV-------------RDGR----LHWSE-------------RDPWT-------------------LQAYRHIGEIA--TS----LG--L------QW----GGH-W------------------------------T-S-LR-----DLA----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 540
 541 ------------------------------------------------------------------------------------------------------------------SRHQ---------------A--GLAADLAFV-------------REGR----LLLSE-------------RDPWT-------------------LQAYRHLGEIA--TT----LG--L------QW----GGE-W------------------------------S-S-LR-----DLG----HVEW------------------------------------------------------------------------------------------------------------------------------------------------------------------ 541
 542 -------------------------------YEQ--LGI-TWVITDG-YRSPATQGSLSG-------------------------------------------GVTNAGPL--QSYHQ---------------Y--GLAIDIVSV-R------------DSKI-TYLSDGK-----------QSIADSK------------------------ALGLIG--EQ----LG--L------VW----GGR-F------------------------------KTK-NG----PDYP----HFELHPN--------------------------------------------------------------------------------------------------------------------------------------------------------------- 542
 543 -------------------------------YEQ--LGI-TWVITDG-YRSPAAQGSLSG-------------------------------------------GVTNAGPL--QSYHQ---------------Y--GLAIDIVSV-R------------DSKI-TYLSDGK-----------QSIADSK------------------------ALGLIG--EQ----LG--L------VW----GGR-F------------------------------KTK-NG----PDYP----HFELHPN--------------------------------------------------------------------------------------------------------------------------------------------------------------- 543
 544 ---------------LHPTYQPYVIRLINTAYKK--LGI-TWVVTDG-YRSPAAQGNLSG-------------------------------------------GVTNAGPL--QSYHQ---------------Y--GLAIDVVSV-R------------NGKI-TYLSDGK-----------QSIADSK------------------------AIGLIG--ES----LG--L------VW----GGR-F------------------------------KTK-NG----PDYP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 544
 545 -------------------------------------GI-CWTIKDS-YRSPDAQDALTG-------------------------------------------GVTNAGPL--QSYHQ---------------Y--GLAIDIVSV-R------------NGEIVNYDSRLK-----RQSRQDQAIADQT------------------------LLAPIG--ES----LG--L------IW----GGR-W------------------------------KKP-FD----P--P----HFELHPN--------------------------------------------------------------------------------------------------------------------------------------------------------------- 545
 546 ------------------------IKLINAAYQS--LGI-AWVITDG-YRSPSAQDALPS-------------------------------------------ANTNAKAL--QSYHQ---------------Y--GLAIDIWSV-R------------DGQIVAYNTKIS-----QADRAKIAIDDAK------------------------QIGSIG--LE----LG--L------GW----GGT-W------------------------------KKK--------DYP----HFELKPN--------------------------------------------------------------------------------------------------------------------------------------------------------------- 546
 547 -----------------------------EQCRA--KGI-ELAFVET-YRTHAKQNEYKGMG-K---------------------------------------KYTRSGGG--KSKHQ---------------Y--GLAVDVVPI-V------------NGEA-----------------QWDNLALWR------------------------KIGVIG--EK----LG--L------RW----GGR-W------------------------------RHP-FD----P--G----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 547
 548 --------------------PALREKVEAVQAQLAAEGF-DVRPVEG-YRSPERQAALLASG-S---------------------------------------GVTSVGAF--SSCHN---------------F--GLAVDAAVF-------------VNGE----PSWNL-------------DDAHV-------------------MAGYQRFGELA--EI----VG--L------NW----GGR-W------------------------------T-S-PK-----DYP----HVELK----------------------------------------------------------------------------------------------------------------------------------------------------------------- 548
 549 --------------------PALREKVEAVQAQLAAEGF-DVRPVEG-YRSPERQAALLASG-S---------------------------------------GVTSVGAF--SSCHN---------------F--GLALDAAVF-------------INGE----PSWNL-------------DDAHV-------------------MAGYQRFGELA--EI----VG--L------NW----GGR-W------------------------------T-S-PK-----DYP----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 549
 550 --------------------PALREKVEAVQAQLAAEGY-DVRPVEG-YRSPERQAALLASA-S---------------------------------------NVTTVGAY--SSCHN---------------F--GLALDAAVF-------------VNGE----PSWNL-------------DDAYV-------------------MAGYQRFGELA--EI----VG--L------NW----GGR-W------------------------------T-N-PK-----DYP----HVELK----------------------------------------------------------------------------------------------------------------------------------------------------------------- 550
 551 ----------------------------------ASQGF-DLRPLEG-FRSPERQAMLTASG-N---------------------------------------GVTRAGAW--ASCHN---------------Y--GLAVDATIY-------------VDDK----PSWNL-------------NDPHV-------------------RAGLQRFGEFS--EV----LG--L------NW----GGR-W------------------------------K-D-PV-----DFP----HVEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 551
 552 -------------------------KLEAVYDVMKERGY-DMRPMEG-MRSEARQAALLASN-A---------------------------------------GVTSVGAG--MSCHN---------------H--GYAVDSVMH-------------VNGK----PTWNM--------HDPHVRDGYK------------------------LFGELV--QA----VD--L------EW----GGN-W--------------------------------TTLQ-----DYP----HVEMK----------------------------------------------------------------------------------------------------------------------------------------------------------------- 552
 553 -------------------------KLEAVYDVMKERGY-DMRPMEG-MRSEARQAALLASN-A---------------------------------------GVTSVGAG--MSCHN---------------H--GYAVDSVMH-------------VNGK----PTWNM--------HDPHVRDGYK------------------------LFGELV--QA----VD--L------EW----GGN-W--------------------------------TTLQ-----DYP----HVEMK----------------------------------------------------------------------------------------------------------------------------------------------------------------- 553
 554 ---------------------ELRSALERIALQMKDEGY-DLRLMEG-YRSKQRQAELLASQ-K---------------------------------------GVTQVGRG--SSCHN---------------H--GWAADMVIY-------------KRGR----PSWDL--------------------------------KDEQVRQGYQRFGELA--QQ----AG--L------RW----GGA-W------------------------------K-S-FK-----DMP----HVE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 554
 555 -----------------PK------------------------------------------------GQ----------------------------------HVTNALPG--MSWHQ---------------W--GEAVDCYWE-------------VNGK----PEWD-------PDAVHGGVKGYH------------------------VYADLAETKQ----IG--L------NA----GGH-W------------------------------S-S-FK-----DWP----HVQLR----------------------------------------------------------------------------------------------------------------------------------------------------------------- 555
 556 -----------------PK------------------------------------------------GQ----------------------------------HVTNALPG--MSWHQ---------------W--GEAVDCYWE-------------VNGK----PEWD-------PDAVHGGVKGYH------------------------VYADLAETKQ----IG--L------NA----GGH-W------------------------------S-S-FK-----DWP----HVQLR----------------------------------------------------------------------------------------------------------------------------------------------------------------- 556
 557 --------------------------------------------------------------------------------------------------------LSKAKPG--QSAHN---------------V--GLAVDIVHG--------------------TKAWDL------------TRKQWD------------------------LVGHIG--KE----VA--ASLGIKVEW----GGD-W--------------------------------S-FY-----DPA----HWEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 557
 558 --------------------------VRVLPKRMAKHGV-PMFASEV-WRSDERQNQLFEQG------------------------------------------FSKARAG--QGPHP---------------F--GCAADLVHG--------------------VRGWNL------------NRDQWR------------------------LVGHIG--QE----LV--TQKGLNLVW----GGN-W------------------------------P-D-FY-----DPA----HWQV------------------------------------------------------------------------------------------------------------------------------------------------------------------ 558
 559 ------------------------------------TEV-DFTVVEG-VRTVAQQREYVTRG-A---SK------------------------------------SMN------SYHL----------PQADGL--GHAVDLAPL------V-------GG----AIPWNN----------------WQ-----------------GFADLAAVVKACA--AE----LG--V----PVEW----GGD-W------------------------------K-S-FK-----DGP----HFQIP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 559
 560 ----------------------------QR------TAV-DFTVVEG-VRTVAQQREYVARG-A---SQ------------------------------------TMA------SCHL----------PQADGL--GHAVDLAPL------V-------GG----AIPWND----------------WQ-----------------AFADLAAVVKACA--AE----LG--V----PVEW----GGD-W------------------------------K-S-FK-----DGP----HFQIPRDWRG------------------------------------------------------------------------------------------------------------------------------------------------------------ 560
 561 --------------------------------------V-DFMVVEG-VRTLAQQRDYVARG-A---SR------------------------------------TMS------SYHL----------PQTDGF--GHAVDLAPL------M-------GG----AIPWNN----------------WS-----------------AFSDLAAVVKACA--AE----LG--V----PVEW----GGD-W------------------------------K-S-FK-----DGP----HFQIPRDWRG------------------------------------------------------------------------------------------------------------------------------------------------------------ 561
 562 -------------------------------------------VVEG-VRTVAQQCEYVARG-T---SK------------------------------------TMN------SYHL----------PQADGL--GHAVDLAPL------T-------GG----AIPWGD----------------WS-----------------KFKGLADVVKACA--AE----LG--V----PLEW----GGD-W------------------------------K-T-FK-----DGP----HFQIPREWKG------------------------------------------------------------------------------------------------------------------------------------------------------------ 562
 563 --FSLSARSLQRLDGVHPRLVEIVKLAIQR------TAV-DFTVVEG-VRTPERQRELVAQG-A---SQ------------------------------------TQN------SLHL----------QQQDGY--GHAVDLAPL------V-------GG----AIPWND----------------WE-----------------QFRRLADVVKACA--AE----LG--T----PVEW----GGD-W------------------------------K-S-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 563
 564 ---------------------------ARR------YEG-KFIVVEG-LRTPERQRELVAKG-A---SQ------------------------------------TRD------SYHL----------RQADGY--GHAVDLAPL------V-------AG----AIPWDN----------------WP-----------------AFAGLAAVVKACA--AE----LG--V----PVEW----GGD-W------------------------------R-T-LK-----DGP----HFQIP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 564
 565 ----------------------------------------DFQVGEG-LRSKAQQVANVKKG-V---ST------------------------------------TMH------SRHL----------D-------GHAVDLLPV------V-------NG----APTY-D----------------WK-----------------YYYPMAKAVKQAA--KE----VG--V----PIEW----GGD-W------------------------------K-T-FK-----DGP----HFQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 565
 566 ---------------------KVVRTAIAE------STF-DFMVVEG-KRSKARQAALVKSG-A---SK------------------------------------TMN------SRHL----------T-------GHAVDLAPVTV----E-------NGKT--VIDWNN----------------KA-----------------KFKVLAELVKAIG--KR----LH--I----EVEW----GGD-W------------------------------R-S-FY-----DGP----HFQLS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 566
 567 ------------LVGVHPDLVKVVRTAIAE------STF-DFMVVEG-KRSKARQAALVKSG-A---SK------------------------------------TMN------SRHL----------T-------GHAVDLAPVTV----E-------NGKT--VIDWNN----------------KA-----------------KFKALAELVKAIG--KR----LH--I----EVEW----GGD-W------------------------------R-S-FY-----DGP----HFQLSRQAY------------------------------------------------------------------------------------------------------------------------------------------------------------- 567
 568 ------------------------RTAISE------SDF-DFMVVEG-KRSKARQAELVKSG-A---SK------------------------------------TMN------SRHL----------T-------GHAVDLAPITV----E-------KGKT--VIDWKN----------------KA-----------------KFNALAELVKSIG--KR----LN--I----DVEW----GGD-W------------------------------R-T-FY-----DGP----HFQLS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 568
 569 ---------------------KVVRAAITE------SEF-DFMVIEG-KRSKARQAELVKRG-A---SK------------------------------------TMN------SRHL----------T-------GHAVDLAPITV----E-------NGKA--VIDWNN----------------KA-----------------KFKTLAELIKSIG--KR----LN--I----DVEW----GGD-W------------------------------R-S-FY-----DGP----HFQLS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 569
 570 ------------------------RTAITE------SEF-DFMVIEG-KRSKARQAELVKSG-A---SK------------------------------------TMN------SRHL----------T-------GHAVDLAPITV----E-------NGKT--VIDWNN----------------KA-----------------KFKTLAELIKSIG--KR----LN--I----DVEW----GGD-W------------------------------R-S-FY-----DGP----HFQLS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 570
 571 ---------------VHRDLVKVVRLALHQ------TDM-DFRVIEG-VRNMARQRQLVSSG-K---SQ------------------------------------TLH------SRHL----------T-------GHAIDLAPW------V-------NH----TIPWHD----------------WD-----------------AFALVSKAMKQAA--IQ----LS--T----PIVW----GGD-W------------------------------K-T-LK-----DGP----HFELA----------------------------------------------------------------------------------------------------------------------------------------------------------------- 571
 572 ------------MRGVHGDLIKVVRLALRK------SEI-DFRVIEG-VRNMARQRQLVSSG-K---SH------------------------------------TLQ------SRHL----------T-------GHAIDLAPW------I-------NH----TIPWED----------------WN-----------------AFALLAKAMKQAA--AQ----LS--T----PIVW----GGD-W------------------------------K-T-LK-----DGP----HFELAKGIY------------------------------------------------------------------------------------------------------------------------------------------------------------- 572
 573 DRYHFSRISEQNLRGVHGDLVNVVRLALRL------SQI-DFRVIEG-MRNTARQRQLVSSG-K---SQ------------------------------------TLN------SRHL----------T-------GHAVDLAPW------V-------NH----SIPWQD----------------WE-----------------AFALVAKAMKKAA--AQ----LD--I----PLVW----GGD-W------------------------------K-T-LK-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 573
 574 DRYHFSRISEQNLRGVHGDLVNVVRLALRL------SQI-DFRVIEG-MRNTARQRQLVSSG-K---SQ------------------------------------TLN------SRHL----------T-------GHAVDLAPW------V-------NH----SIPWQD----------------WE-----------------AFSLVAKAMKKAA--AQ----LD--I----PLVW----GGD-W------------------------------K-T-LK-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 574
 575 ------------LRGVHSDLVKVVRLALRL------SQI-DFRVIEG-MRNMARQRQLVSSG-K---SQ------------------------------------TLN------SRHL----------T-------GHAVDLAPW------V-------NH----SIPWQD----------------WD-----------------AFVLIAKAMKKAS--AQ----SE--I----PLVW----GGD-W------------------------------K-T-LK-----DGP----HFELTREKY------------------------------------------------------------------------------------------------------------------------------------------------------------- 575
 576 --------------------------------------I-DFCVIEG-VRDISRQRQMVLTG-K---SQ------------------------------------TLN------SRHL----------T-------GHAVDLAPW------I-------NQ----SIPWDN----------------WS-----------------AFKVVADAMKVSA--EK----LT--I----PIVW----GGD-W------------------------------Q-T-LK-----DGP----HFELS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 576
 577 --------------------------------------I-DFCVIEG-VRDISRQRQMVLTD-K---SQ------------------------------------TLN------SRHL----------T-------GHAVDLAPW------I-------NQ----SIPWDN----------------WS-----------------AFKVVADAMKISA--EK----LN--I----LIVW----GGD-W------------------------------K-T-LK-----DGP----HFELSRKSY------------------------------------------------------------------------------------------------------------------------------------------------------------- 577
 578 -------------------------------------------VIEG-VRSLERQRQLVRNG-S---SK------------------------------------TLN------SRHL----------T-------GHAVDLAPL------I-------NN----KIPWED----------------WQ-----------------AFDQVAKAMKQAA--KE----ME--L----PLQW----GGD-W------------------------------K-T-FK-----DGP----HFELPREVY------------------------------------------------------------------------------------------------------------------------------------------------------------- 578
 579 -----------NLRGIHPDLVLIVRRALTL------STV-DFRVIEG-VRTSERQRQLVRNG-S---SK------------------------------------TLN------SRHL----------T-------GHAVDLAPM------V-------NN----QIPWED----------------WS-----------------AFHLVAKAMKQAA--KE----ME--L----PLQW----GGD-W------------------------------K-T-FK-----DGP----HFELPREVY------------------------------------------------------------------------------------------------------------------------------------------------------------- 579
 580 --------------------------------------V-DFRVIEG-IQTAERQRQLVRNG-S---SK------------------------------------TLN------SRHL----------T-------GHAVDLAPL------I-------NN----KIPWED----------------WG-----------------AFHQVAKAMKQAA--LE----ME--L----PLQW----GGD-W------------------------------K-S-FK-----DGP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 580
 581 -------------------------------------HI-DFRVIEG-IRTPERQRQMVLNG-H---SK------------------------------------TMN------SRHL----------T-------GHAVDLAPM------V-------NN----RIPWDD----------------WH-----------------AFAHVAKAMKQAA--KV----ME--L----PLLW----GGD-W------------------------------K-N-FR-----DGP----HFELPR---------------------------------------------------------------------------------------------------------------------------------------------------------------- 581
 582 -----------NLHHVHPDLVLIVRRALTL------SHI-DFRVIEG-IRTPERQRQMVLNG-H---SK------------------------------------TMN------SRHL----------T-------GHAVDLAPM------V-------NN----RIPWDD----------------WH-----------------AFAHVAKAMKQAA--KA----ME--L----PLQW----GGD-W------------------------------K-N-FR-----DGP----HFELPRECY------------------------------------------------------------------------------------------------------------------------------------------------------------- 582
 583 -----------NLHHVHPDLVLIVRRALTL------SHI-DFRVIEG-IRTPERQRQMVLNG-H---SK------------------------------------TMN------SRHL----------T-------GHAVDLAPM------V-------NN----RIPWDD----------------WH-----------------AFVHVAKAMKQAA--KA----ME--L----PLQW----GGD-W------------------------------K-N-FR-----DGP----HFELPRECY------------------------------------------------------------------------------------------------------------------------------------------------------------- 583
 584 ----------------------------------------DFIVIEG-LRTAESQKKMVNSG-H---SQ------------------------------------TLN------SRHL----------T-------GHAVDLAPL------I-------NG----MIPWSN----------------WS-----------------NFAELANTVKQAA--QN----LN--I----PIIW----GGD-W------------------------------I-S-LK-----DGP----HFELS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 584
 585 -----------NLIGVHPDLVKVTRLALQL------SNT-DFCVIEG-LRTAERQRQMFADG-H---SQ------------------------------------TLN------SRHL----------T-------GHAVDLAPL------I-------NS----TIPWDN----------------WQ-----------------AFIELATTVKQAA--QR----LN--I----PIIW----GGD-W------------------------------K-S-LK-----DGP----HFELPRQYY------------------------------------------------------------------------------------------------------------------------------------------------------------- 585
 586 QNFIFSHRSEKNLQGVHPDLVRLVRSALLL------SEV-DFCVIEG-VRTLDRQRQLMREG-H---SQ------------------------------------TLN------SRHL----------T-------GHAVDLAPL------I-------EK----TIPWDR----------------WE-----------------FFQMVAEVMKESA--MR----AD--I----PIIW----GGD-W------------------------------K-N-FK-----DGV----HFELSREHYA------------------------------------------------------------------------------------------------------------------------------------------------------------ 586
 587 --------SQSNLKGVHQDLVRVVHLAITF------SEY-DFVVIEG-IRSLARQKALIKEG-K---SK------------------------------------TLN------SRHL----------T-------GHAVDIVPI------V-------NG----VIPWQD----------------WS-----------------AFEAVSKVMKQAA--QQ----LG--I----SINW----GGD-W------------------------------A-S-FR-----DGP----HYEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 587
 588 ----------------------------------------DFVVIEG-VRSLERQKALIKEG-K---SK------------------------------------TLN------SRHL----------T-------GHAVDIVPL------V-------NG----AIPWQD----------------WS-----------------AFESVSKAMKQAS--SQ----LG--V----SINW----GGN-W------------------------------V-S-FR-----DGP----HYELCREAY------------------------------------------------------------------------------------------------------------------------------------------------------------- 588
 589 --------------------------ALTL------SEY-DFVVIEG-LRSFVRQKVLMKEG-K---SK------------------------------------TLN------SRHL----------T-------GHAVDIVPL------V-------NG----SIPWHD----------------WS-----------------AFESVSKAMKQAA--HQ----LG--V----SMNW----GGD-W------------------------------V-S-FR-----DGP----HYELS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 589
 590 --------------------------------------M-DFTVLEG-VRSLARQKQLVARG-A---SK------------------------------------TMN------SRHLPKVPKGGGEPV-------AHAVDLGAY------V-------DG----EVRW-D----------------WP-----------------LYHKIAKAVKQAA--RE----LN--V----PIEW----GGD-W------------------------------R-T-FK-----DGP----HWQLPW---------------------------------------------------------------------------------------------------------------------------------------------------------------- 590
 591 --YVLSQRSLARLDGVHPDLVRVVRRAIQI------TEI-DFVVTEG-VRTLEKQKDMVARG-A---SK------------------------------------TMN------SRHL-KAANG----Y-------SHAVDLAAL------V-------GG----SVVW-D----------------WP-----------------LYAKLAKAMKQAA--KE----LG--I----PLEW----GGD-W------------------------------K-S-FK-----DGP----HFQLPW---------------------------------------------------------------------------------------------------------------------------------------------------------------- 591
 592 ------------------------------------------TVGEG-LRTIETQRKYVAEG-K---SK------------------------------------TMN------SRHL----------T-------GHAVDLWPL------V-------DG----KVSW-D----------------WK-----------------YYYPLADAMKAAA--KE----LG--V----PLEW----GGD-W------------------------------T-T-FK-----DGP----HFQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 592
 593 --FKLGSRSLQRLQGVHPDLVKVVKRAIEI------SPV-DFTVTEG-LRTLERQKELFAKG-A---SK------------------------------------TMR------SRHL----------T-------GHAVDISPL------V-------DG----KVSW-D----------------WK-----------------YYYPMADAMKQAA--KE----LN--I----PVEW----GGD-W------------------------------K-T-FK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 593
 594 ------------------------------------TEV-DFRVSEG-LRTKARQAELVKSG-A---SQ------------------------------------TQN------SRHL----------T-------GHAVDLVAM------I-------GL----DIRW-D----------------WP-----------------LYYKIADAVKQAA--KE----LN--V----PIEW----GGD-W------------------------------K-T-FK-----DGP----HFQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 594
 595 --YTLSKRSLDNLKGVHPDLVAVVHRAIQL------TPV-DFAVIEG-LRSVSRQKELVAAG-A---SK------------------------------------TMN------SRHL----------T-------GHAVDLAAY------V--------N----GIRW-D----------------WP-----------------LYDAIAVAVKAAA--KE----LG--V----AIVW----GGD-W------------------------------T-T-FK-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 595
 596 --------------------------------------V-DFTVLEG-LRTIERQRRLLSSG-S---ST------------------------------------TLR------SRHL----------T-------GHAVDLGAW------I-------DG----TVDW-S----------------WP-----------------LYYKIADAMKQAA--EE----LR--I----PIEW----GGD-W------------------------------R-T-FK-----DGP----HFQLSWAQYPED---------------------------------------------------------------------------------------------------------------------------------------------------------- 596
 597 ----------------------------EI------TDV-DFMVLEG-LRTVERQEELFSSG-A---SR------------------------------------TMN------SRHL----------T-------GHAVDLGAY------V-------AS----SVRW-D----------------WP-----------------LYHKIADAMKQAA--NE----LN--I----PIQW----GGD-W------------------------------S-S-FK-----DGP----HFQLPHSDY------------------------------------------------------------------------------------------------------------------------------------------------------------- 597
 598 ------------------------------------TPI-DFKVIEG-RRTLERQRELVKAG-A---SQ------------------------------------TLN------SRHL----------T-------GHAVDIVPL------P-------DG----KVSW-E----------------WK-----------------YFYPMADAMKQAA--AE----LG--I----VVEW----GGN-W------------------------------T-T-FK-----DGP----HFQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 598
 599 --------------------------------------I-DFKVIEG-RRTIERQRDLVKAG-A---SQ------------------------------------TLN------SRHL----------T-------GHAVDIVPL------P-------DG----KISW-E----------------WR-----------------YFYPMADAMKQAA--AE----LG--I----AVEW----GGN-W------------------------------T-T-FK-----DGP----HFQLPARQY------------------------------------------------------------------------------------------------------------------------------------------------------------- 599
 600 --FIFGKASESNLIGVHPDLVKVVRRALEL------TPL-DFKVIEG-RRTLERQRQLVKAG-A---SQ------------------------------------TLN------SRHL----------T-------GHAVDIVPL------P-------NG----KVSW-E----------------WQ-----------------YFRPMAEAVKQAA--AE----LG--I----AVEW----GGN-W------------------------------T-T-FK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 600
 601 ------------------------------------TSI-DFKVIEG-VRTLERQRQLVNAG-A---SQ------------------------------------TMN------SRHL----------T-------GHAVDIVPL------P-------DG----KVSW-E----------------WK-----------------YFYPMADAMKQAA--AE----LG--I----AVEW----GGN-W------------------------------T-T-FK-----DGP----HFQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 601
 602 --FIFGKASESNLIGVHPDLVKVVRRALEI------TPI-DFKVIEG-CRTVERQRELVKDS-A---SQ------------------------------------TMN------SRHL----------T-------GHAVDIVPL------P-------NG----KVSW-E----------------WK-----------------YFYPMADAMKQAA--AE----LG--I----AVEW----GGN-W------------------------------T-T-FK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 602
 603 --FILGKASESNLIGVHPDLVKVVRRALEL------TPL-DFKVIEG-CRTLERQRELVKVG-A---SQ------------------------------------TLN------SRHL----------T-------GHAVDIVPL------P-------DG----KISW-E----------------WK-----------------YFYPMADAMKRAA--AE----LK--I----AVEW----GGN-W------------------------------T-T-FK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 603
 604 ------------------------------------TTI-DFRVIEG-LRTKERQRQLVNSG-A---ST------------------------------------TMN------SRHL----------T-------GHAIDIVPL------P-------DG----KVSW-D----------------WK-----------------YFYPLAEAMKRAA--DE----LG--V----PLEW----GGD-W------------------------------K-T-FK-----DGP----HFQLS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 604
 605 --FKFSQRSENNLKGVYPDLVAVVHRALAL------TPV-DFTVIEG-LRTIERQKQLFAAK-K---SQ------------------------------------TMK------SRHL----------H-------GFAVDLYPG--------------------SWEWTE----------------F--------------------YKLEKAMKTAA--SE----LG--I----PIEW----GGD-WKS--------------------------------FK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 605
 606 ------------------------DRAIAT------TDI-DFTVLEG-MRTMSRQRKLVASG-A---SR------------------------------------TLR------SRHL----------T-------GHAVDIAPL------V-------DG----KVSW-D----------------WP-----------------IYHRLAPTIKKAA--QD----VG--V----KIEW----GGD-W------------------------------R-S-FK-----DGP----HWQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 606
 607 ------------------------------------TPV-DFQILEG-VRSLARQKQLVAQG-A---ST------------------------------------TLR------SRHL----------T-------GHAVDIAPL------I-------DG----KVSW-H----------------WP-----------------HYYPLAEAIKKAA--KE----VG--V----AIEW----GGD-W------------------------------K-S-FK-----DGP----HWQLPH---------------------------------------------------------------------------------------------------------------------------------------------------------------- 607
 608 ----------------------------------------DFTVVEG-VRSLDRQKRLYASG-A---ST------------------------------------TMN------SRHL----------T-------GHAVDMIPY------PFHGDFDGDG----VPNIED----------------WD-----------------QYYPIATAMKTAA--LQ----LG--I----EIEW----GGD-W------------------------------K-S-FK-----DGP----HWQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 608
 609 -------------------------------------SV-DFRVIEG-VRSEERQRQLVRNG-A---SQ------------------------------------TLN------SRHI----------T-------GHAVDCAPL------V-------NS----AIPWND----------------QS-----------------KFKAVSDAMFQAA--KE----LG--V----RIRW----GGD-WNENGRSND----------------------E-K-FY-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 609
 610 -------------------------------------KV-DFKVIEG-KRSEARQRQLVVNG-K---SK------------------------------------TMN------SRHL----------T-------GHAVDCAPL------V-------AG----VIPWND----------------RK-----------------AFASVSKAMFAAA--NE----LG--I----PLRW----GGD-WNQNGRSDD----------------------E-R-FY-----DGP----HFELP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 610
 611 SKFKFSKRSEENLRGVHPDLVKVTRRAIEL------TNI-DFMVIEG-KRTEARQRQLVKNG-A---SQ------------------------------------TMN------SRHL----------T-------GHAVDCAPL------V-------NR----EIPWND----------------WS-----------------KFKLVADAMLQAA--KE----LN--V----DLEW----GGN-WKS--------------------------------FK-----DGP----HFQLTHKSY------------------------------------------------------------------------------------------------------------------------------------------------------------- 611
 612 -----------NLRGVHPDLVKVVRRAIKL------SRV-DFMVIEG-KRNEARQRQLVANG-Q---SQ------------------------------------TMN------SRHL----------T-------GHAVDCAPL------I-------HR----QIPWND----------------WS-----------------KFELVARAMKKAA--AE----LN--V----EIEW----GGD-WVN--------------------------------FK-----DGP----HFQLSYRAY------------------------------------------------------------------------------------------------------------------------------------------------------------- 612
 613 ------------------------------------TDV-DFMVIEG-KRNEARQRQLVING-K---SR------------------------------------TMN------SRHL----------T-------GHAVDCAPI------V-------NG----SIPWQE----------------WS-----------------YFKKVADAMSQAG--KE----FG--I----DVEW----GGN-WDS--------------------------------FK-----DGP----HFQLT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 613
 614 -----------------------VRKALEY------STV-DFAVIEG-VRTKARQAQLFKQG-A---TK------------------------------------TMN------SRHL----------T-------GHAVDLAPL------V-------EG----KIPWSE----------------RD-----------------KFKEIAKAMFRAA--KE----LN--V----TIRW----GGD-WNGNGKSED----------------------E-R-FY-----DGP----HFELH----------------------------------------------------------------------------------------------------------------------------------------------------------------- 614
 615 ----FSQRSEKHLQGVHDDLVKVVRKALEY------STV-DFAVIEG-VRTKARQAQLFKQG-A---TK------------------------------------TMN------SRHL----------T-------GHAVDLAPL------V-------EG----KIPWSE----------------RD-----------------KFKEIAKAMFRAA--KE----LN--V----TIRW----GGD-WNGNGKSED----------------------E-R-FY-----DGP----HFELHRAVY------------------------------------------------------------------------------------------------------------------------------------------------------------- 615
 616 -------------------------------------TV-DFAVIEG-VRTKERQAQLFKQG-A---TK------------------------------------TMN------SRHL----------T-------GHAVDLAPL------V-------EG----KIPWSE----------------RD-----------------KFKEIAKAMFRAA--KE----LN--V----TIRW----GGD-WNGNGKSED----------------------E-R-FY-----DGP----HFELH----------------------------------------------------------------------------------------------------------------------------------------------------------------- 616
 617 -------------------------RAKAI------ASL-DFIVIEG-VRSIIRQKELVGQG-A---SR------------------------------------TMN------SRHL----------T-------GHAIDLAPW------M-------DG----AIPWEN----------------WP-----------------AFEEVGLAMKKAA--SG----LK--I----PIVW----GGD-W------------------------------K-N-FR-----DGP----HFELP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 617
 618 ---------------VHVDLVMVARRAKAI------ASL-DFIVIEG-VRSIIRQKELVGQG-A---SR------------------------------------TMN------SRHL----------T-------GHAIDLAPW------M-------DG----AIPWEN----------------WP-----------------AFEEVGLAMKKAA--SE----LK--I----PIVW----GGD-W------------------------------K-N-FR-----DGP----HFELPRVYY------------------------------------------------------------------------------------------------------------------------------------------------------------- 618
 619 ------------------------------------------------------------------------------------------------------------------SKHT----------T-------GKAVDLVPY--------------------PVDWND----------------LS-----------------KFKKIAVAMKQAA--KE----LG--V----ELDW----GGD-W------------------------------K-S-SK-----DYP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 619
 620 --------------------------------------------------------------------------------------------------------------------HV----------T-------GHAVDLVPY--------------------PVDWND----------------LN-----------------KFKKISVAMKQAA--KD----LG--V----ALDW----GGD-W------------------------------R-S-SK-----DYP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 620
 621 -------------------------------------------------------------------------------------------------------------------KHT----------T-------GKAIDLIPY--------------------PVDWND----------------LK-----------------KFHMIATAMKQAA--AE----LG--V----KIKW----GGD-W------------------------------K-K-SK-----DYP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 621
 622 --FKLSAASEEKLVGVHADLVKVAHRAIEL------SVV-DFKVIEG-KRTLERQKELFAKK-A---TK------------------------------------TMN------SRHL----------T-------GHAVDLVPL--------------------PVNWND----------------RE-----------------PFKNVASAMFQAA--KQ----LG--V----AIRW----GGD-WNMNESSDD----------------------E-H-FY-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 622
 623 -------------------------------------EC-DFTVTEG-LRSKERQAQLLKEK-K---TT------------------------------------TSN------SRHL----------T-------GHAVDLAAW------V-------NN----TVSW-D----------------WK-----------------YYYQIADAMKKAA--SE----LN--V----SIDW----GGD-W------------------------------K-K-FK-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 623
 624 -------------------------------------AQ-DFIVTEG-VRTPERQRELYAQG-R---TK----PGK------IVT----------------K-------TL--TSNHF----------KHADGY--GHAVDLT---------------------------------------------PY-----PVDYEGPVKFPKHEAIAKAMKAAA--AE----LG--V----KIQW----GGD-W------------------------------K-G-FI-----DRP----HYELI----------------------------------------------------------------------------------------------------------------------------------------------------------------- 624
 625 ---KLGQRSLDRLKGVNPPLVAVFKRACETMPF-------DVTVLEG-LRSYERQQELLKQG--------------------------------------------ATKVS--ISRH-----------------MSGNALDIAPY--------------------PIDWND---------------------------------LERFQIVAEHMFKAA--KE----LGIVI------RW----GGT-WER--SFTKPV--------------------KWAKFL-----DAP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 625
 626 ----------------------------ETLTF-------DVTVIEG-VRDQKRQAQLFAEG--------------------------------------------KTKVM--TSRH-----------------MSGNAVDMAPY--------------------PVDWND---------------------------------TERFVILAHHMFAAA--KE----LGITI------RW----GGN-WSRIDENQKPP----------------------SSFV-----DMP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 626
 627 -------------------------------------PV-DFMITEG-LRTPARQAELVRAG-A---SR------------------------------------TLN------SRHL----------T-------GHAVDVAAW------I-------DG----EVRW-D----------------WP-----------------LYPRIAEAFKAAA--KD----RD--V----ALIW----GGD-W------------------------------P-R-LR-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 627
 628 MSFRLSQRSRAALQGVHPDLVAVVEAALEL------TPV-DFMVTEG-LRTAARQAELVRAG-A---SR------------------------------------TLN------SRHL----------T-------GHAVDVAAW------V-------GG----QVRW-D----------------WP-----------------LYPRIAEAFKAAA--KG----RG--V----RLIW----GGD-W------------------------------P-R-LR-----DGP----HFELDRGAY------------------------------------------------------------------------------------------------------------------------------------------------------------- 628
 629 --------------------------------------V-DFMVTEG-LRTPARQAELVRAG-A---SR------------------------------------TLN------SRHL----------T-------GHAVDVAAW------V-------DG----GVRW-D----------------WP-----------------LYPRIAGAFKEAA--AA----AS--A----PLIW----GGD-W------------------------------P-R-LR-----DGP----HFELDRRAY------------------------------------------------------------------------------------------------------------------------------------------------------------- 629
 630 ----LSSRSRDHLKGVHPALAGVIEAAILT------SPV-DFMVTEG-LRSPARQAALVKAG-A---SR------------------------------------TLN------SRHL----------T-------GHAVDLAAL------V-------DG----RIRW-D----------------WP-----------------LYPRIAAHIKATA--AA----RG--V----ALVW----GGD-W------------------------------P-R-LR-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 630
 631 -------------------------AAVAR------SPV-DFMITEG-LRSPERQAALVQAG-A---SR------------------------------------TLR------SRHL----------S-------GHAVDVAAL------V-------DG----QVRW-D----------------WP-----------------LYGRIASAFKAAA--VE----LK--T----PIVW----GGD-W------------------------------K-S-LR-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 631
 632 ----LSVRSRARLKGVHPALVAVVEAAVAR------SPV-DFMITEG-LRSPERQAALVQAG-A---SR------------------------------------TLR------SRHL----------S-------GHAVDVAAL------V-------EG----QVRW-D----------------WP-----------------LYGRIASAFKAAA--LE----LK--T----PIVW----GGD-W------------------------------K-S-LR-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 632
 633 ------------------------------------TPV-DFMITEG-LRTAERQAALVKVG-A---SR------------------------------------TTR------SRHL----------T-------GHAVDVAAL------V-------EG----QVRW-D----------------WP-----------------LYGRIAEAFKAAA--LD----LK--T----PLIW----GGD-W------------------------------K-T-LR-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 633
 634 ------------------------------------TPV-DFMITEG-LRTAERQAALVKVG-A---SR------------------------------------TTR------SRHL----------T-------GHAVDVAAL------V-------EG----QVRW-D----------------WP-----------------LYGRIAEAFKAAA--LD----LK--T----PLIW----GGD-W------------------------------K-T-LR-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 634
 635 -----------ALAGVHDDLVRVARRALEL------TEV-DFVVTEG-RRTEARQRSLVAAG-A---SR------------------------------------TMR------SRHL----------T-------GHALDVAAW------V-------DG----GVRW-D----------------WP-----------------LYPRIAAAFKAAA--AE----LG--V----AIRW----GGD-W------------------------------P-R-FR-----DGP----HFELDRRSY------------------------------------------------------------------------------------------------------------------------------------------------------------- 635
 636 --------------------------------------V-DFCVTEG-VRTAERQRELVAKG-A---ST------------------------------------TTN------SRHIPKKPAAR---PELGPV--SHAVDLAAM------I-------GA----EVRW-D----------------WP-----------------LYHKLADAMKTAA--FK----LK--V----PIAW----GGD-W------------------------------T-S-FK-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 636
 637 ------TRSESRLNGVHADLAKVVRRCAKD------SKI-EFIVTEG-RRTMERQKALVAAG-A---SK------------------------------------TLK------SRHL----------T-------GHAIDLAVK------V-------GG----KVRW-D----------------WP-----------------LYARLAADMKKAA--AA----VG--V----PIEW----GGD-W------------------------------R-S-LK-----DGP----HFQLPWAKY------------------------------------------------------------------------------------------------------------------------------------------------------------- 637
 638 ------------------------------------SAV-DFGVTEG-LRSMAREKEMVAEG-H---SE------------------------------------TMH------SRHL----------T-------GHAVDVVAY------V-------NG----AVSW-D----------------WS-----------------LYEQIAAAFKQAS--AS----LG--V----PVEW----GGD-W------------------------------K-T-LK-----DGA----HFQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 638
 639 ----FSERSETNLKGVNSDLVKVARLALEL------SPV-DFGITEG-LRDMAKQREMVRTG-K---SQ------------------------------------TLK------SRHL----------T-------GHAVDVVAY------V-------GG----KVSW-D----------------WG-----------------PYEQIAKAFKLAG--SQ----LG--I----KIEW----GGD-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 639
 640 ---------------------KVVRRALQL------SAV-DFGITEG-LRSVERQKQLVAEG-K---SQ------------------------------------TMN------SRHL----------S-------GHAVDVFAY------P-------TP----AGSW-D----------------WK-----------------FYQQISEAFKQAG--KE----LN--I----PIEW----GGD-W------------------------------K-T-LK-----DGP----HFQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 640
 641 SEFKFSQRSGNNLKGVNADLVKVVRRALHL------SAV-DFGITEG-LRSVERQKQLVAEG-K---SQ------------------------------------TMN------SRHI----------S-------GHAVDVFAY------P-------TP----AGSW-D----------------WK-----------------YYQQISEAFKQAG--KE----LN--I----PVEW----GGD-W------------------------------K-T-LK-----DGP----HFQLPYAAY------------------------------------------------------------------------------------------------------------------------------------------------------------- 641
 642 ---------------------KVVRRALQL------SAV-DFGITEG-LRTVERQKKLVAEG-K---SQ------------------------------------TMN------SRHI----------S-------GHAVDVFAY------P-------TP----AGSW-D----------------WK-----------------YYQQISEAFKQAG--KE----LN--I----PVEW----GGD-W------------------------------K-T-LK-----DGP----HFQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 642
 643 ----FSQRSENNLKGVNADLVKVVRRAIQL------SAI-DFGVTEG-LRSVERQKQLVAEG-K---SQ------------------------------------TMN------SRHI----------S-------GHAVDVFAY------P-------TP----AGSW-D----------------WK-----------------YYQQISEAFKQAG--KE----LN--V----PVEW----GGD-W------------------------------T-T-LK-----DGP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 643
 644 ----FSQRSENNLRGVHPDLVKVVRLALEL------SPV-DFGITEG-LRTVERQKQLVAEG-K---SQ------------------------------------TMN------SRHI----------S-------GHAVDVFAY------P-------TP----AGSW-D----------------WQ-----------------YYQQISQAFKQAG--KN----LG--I----PVEW----GGD-W------------------------------K-T-LK-----DGP----HFQLPYADY------------------------------------------------------------------------------------------------------------------------------------------------------------- 644
 645 ---------------------KIVRRALQL------SSV-DFGITEG-LRTVERQRQLVATG-K---SQ------------------------------------TMN------SRHI----------S-------GHAVDVFAY------P-------TS----AGSW-E----------------WK-----------------YYEQIATAFKQAA--KE----LN--I----PVEW----GGD-W------------------------------K-T-LK-----DGP----HFQLPH---------------------------------------------------------------------------------------------------------------------------------------------------------------- 645
 646 ---------------------KIVRRALQL------SPV-DFGITEG-LRTVERQRQLVAAG-K---SQ------------------------------------TMN------SRHI----------S-------GHAVDVFAY------P-------TS----AGSW-E----------------WK-----------------YYEQIATAFKQAA--KE----LN--I----PVEW----GGD-W------------------------------K-T-LK-----DGP----HFQLPH---------------------------------------------------------------------------------------------------------------------------------------------------------------- 646
 647 ---------------------KIVRRALQL------SPV-DFGITEG-LRTVERQRQLVAAG-K---SQ------------------------------------TMN------SRHI----------S-------GHAVDVFAY------P-------TS----AGSW-E----------------WK-----------------YYEQIATAFKQAA--KE----LN--I----PVEW----GGD-W------------------------------K-T-LK-----DGP----HFQLPH---------------------------------------------------------------------------------------------------------------------------------------------------------------- 647
 648 -------------------------------------PV-DFAITEG-VRSIERQKQLVAAG-K---SQ------------------------------------TSN------SRHL----------T-------GHAVDVFAY------P-------TS----AGSW-E----------------WK-----------------YYVQIANAFKAAA--NE----LR--I----VIEW----GGD-W------------------------------K-S-LK-----DGP----HYQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 648
 649 -------------------------------------VV-DFGVTEG-LRTVARQKELVAAG-K---SQ------------------------------------TMN------SRHI----------T-------GHAIDVFAY------P-------TA----SGSW-E----------------WK-----------------YYEQISTAFKQAA--KD----IG--V----PIEW----GGD-W------------------------------K-T-LK-----DGP----HFQLPH---------------------------------------------------------------------------------------------------------------------------------------------------------------- 649
 650 -------------------------------------PI-DFGVTEG-LRTVARQKELVAAG-K---SQ------------------------------------TMN------SRHI----------T-------GHAIDVFAY------P-------TA----SGSW-E----------------WK-----------------YYEQISAAFKQAA--KD----VG--V----PIEW----GGD-W------------------------------K-T-LK-----DGP----HFQLPH---------------------------------------------------------------------------------------------------------------------------------------------------------------- 650
 651 --FRFSQRSENNLKGVNPALVQVVRRALEL------SIV-DFGVTEG-LRTVERQKELVAKG-A---SQ------------------------------------TMN------SRHI----------T-------GHAIDVFAY------P-------AA----SGSW-E----------------WK-----------------YYEQIATAFKLAA--KD----VG--V----SIEW----GGD-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 651
 652 --FSFSQRSDSNLRGVHPDLARLARAALQL------SPV-DFGVTEG-LRTLERQKQLVASG-A---SQ------------------------------------TMK------SRHI----------T-------GHAIDVFAY------P-------TN----GGSW-E----------------WK-----------------YYETIAAAFKQAS--EA----MG--I----PVEW----GGD-W------------------------------Q-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 652
 653 ----------------------------------------------------------VAEG-K---SQ------------------------------------TMN------SRHL----------T-------GDAVDVVAW------V-------GS----QVSW-D----------------WP-----------------LYEKIAQAFKQAA--AE----LG--T----AIEW----GGD-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 653
 654 GKFRFSRRSEKNLEGVKPQLVAVVRRALEL------TEV-DFGITEG-LRTKERQKQLVAEG-K---SQ------------------------------------TMN------SRHL----------T-------GDAVDVVAY------I-------GS----QVSW-D----------------WP-----------------LYEKIAQAFKQAA--AE----LG--T----AIEW----GGD-W------------------------------K-T-LK-----DGP----HFQLKW---------------------------------------------------------------------------------------------------------------------------------------------------------------- 654
 655 ------------------------RRALAL------SDV-DFGITEG-LRTKERQKQLVAEG-K---SQ------------------------------------TMN------SRHL----------T-------GDAVDVVAY------V-------GG----TISW-D----------------WP-----------------LYEKIARAFKQAA--AE----LG--V----AIEW----GGD-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 655
 656 ------------------------------------TEV-DFGITEG-LRTKERQKQLVAEG-K---SQ------------------------------------TMN------SRHL----------T-------GDAVDVVAW------V-------GS----QVSW-D----------------LP-----------------LYEKIAQAFKQAS--AE----LN--T----PIEW----GGE-W------------------------------R-S-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 656
 657 ----------------------------------------------------------------------------------------------------------MN------SRHL----------T-------GHAVDVVAY------V-------GS----DISW-D----------------MP-----------------LYQQIAQAFKQAS--AE----LS--I----PVEW----GGD-W------------------------------K-T-LK-----DGP----HFQLPFKEY------------------------------------------------------------------------------------------------------------------------------------------------------------- 657
 658 ------------------------------------SEV-DFGITEG-GRSRYRQKQLVATG-K---SQ------------------------------------TMN------SRHL----------T-------GHAVDVVAY------I-------GS----QVSW-E----------------WP-----------------LYEKIAAAFRQAS--RE----LN--I----PVEW----GGD-W------------------------------K-T-LK-----DGP----HFQLPHG--------------------------------------------------------------------------------------------------------------------------------------------------------------- 658
 659 ------------------------------------SEV-DFGITEG-LRSRYRQKQLVATG-K---SQ------------------------------------TMN------SRHL----------T-------GHAVDVVAY------I-------GS----QVSW-E----------------WP-----------------LYEKIAAAFRQAS--RE----LN--I----PVEW----GGD-W------------------------------K-T-LK-----DGP----HFQLPHG--------------------------------------------------------------------------------------------------------------------------------------------------------------- 659
 660 --FKFSSRSEKNLQGVNPDLVKVTRRALEI------SEV-DFGITEG-LRSRYRQKQLVATG-K---SQ------------------------------------TMN------SRHL----------T-------GHAVDVVAY------I-------GS----QVSW-E----------------WP-----------------LYEKIAAAFRQAS--RE----LN--I----PVEW----GGD-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 660
 661 ------------------------RRALEI------SEV-DFGITEG-LRSRYRQKQLVATG-K---SQ------------------------------------TMN------SRHL----------T-------GHAVDVVAY------I-------GS----QVSW-E----------------WP-----------------LYEKIAAAFRQAS--RE----LN--I----PVEW----GGD-W------------------------------K-T-LK-----DGP----HFQLPHGAY------------------------------------------------------------------------------------------------------------------------------------------------------------- 661
 662 --FKFSSRSEKNLQGVNPDLVKVTRRALEI------SEV-DFGITEG-LRSRYRQKQLVATG-K---SQ------------------------------------TMN------SRHL----------T-------GHAVDVVAY------I-------GS----QVSW-E----------------WP-----------------LYEKIAAAFRQAS--RE----LN--I----PVEW----GGD-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 662
 663 --FKFSSRSEKNLQGVNPDLVKVTRRALEI------SEV-DFGITEG-LRSRYRQKQLVATG-K---SH------------------------------------TIN------SRHL----------T-------GHAVDVVAY------V-------GS----QVSW-E----------------WP-----------------LYEKIAAAFRQAS--QE----LN--I----PVEW----GGD-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 663
 664 --YKFSQRSEKNLVGVNPALVAVARRALEL------SPV-DFGITEG-LRSRERQKQMVAAG-A---SQ------------------------------------TMN------SRHL----------T-------GHAVDVVAY------L-------GS----NISW-E----------------WK-----------------YYEQIAIAFKQAG--AE----LG--T----PIEW----GGD-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 664
 665 --YKFSQRSEKNLVGVNPALVAVARRALEL------SPV-DFGITEG-LRSRERQKQMVAAG-A---SQ------------------------------------TMN------SRHL----------T-------GHAVDVVAY------L-------GS----NISW-E----------------WK-----------------YYEQIAIAFKQAG--AE----LG--T----PIEW----GGD-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 665
 666 --YKFSQRSEKNLVGVNPALVAVARRALEL------SPV-DFGITEG-LRSRERQKQMVAAG-A---SQ------------------------------------TMN------SRHL----------T-------GHAVDVVAY------L-------GS----NISW-E----------------WK-----------------YYEQIAIAFKQAG--AE----LG--T----PIEW----GGD-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 666
 667 ------------------------------------TTV-DFGITEG-LRTVEREKEMVAGG-H---SQ------------------------------------TMN------SRHL----------T-------GHAVDVVAY------V-------GS----QVSW-E----------------WP-----------------LYEQIASAFKQAS--SE----LA--V----PVEW----GGD-W------------------------------T-T-LK-----DGA----HFQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 667
 668 -------------------------------------EV-DFGVTEG-LRTKDRQRQLVAEG-K---SR------------------------------------TAN------SRHL----------T-------GDAIDVVAY------L-------GA----AVTW-E----------------WK-----------------YYEQIAVAFKRAS--AE----LG--I----PVEW----GGD-W------------------------------K-S-LK-----DGP----HFQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 668
 669 --------------------------------------I-DFGITEG-LRTLEKQKEMVRTG-K---SQ------------------------------------TMK------SRHL----------T-------GHAIDVFAY------P-------TP----AGSW-D----------------FA-----------------DYELISNAFKQAA--KS----LG--H----SIEW----GGD-W------------------------------K-T-LK-----DGP----HFQLT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 669
 670 ------ERSLKNLQGVHPDLVAICKKALDL------TLI-DFGITEG-LRSLDKQKEMVRTG-K---SQ------------------------------------TMK------SRHL----------T-------GHAIDVFAY------P-------TP----AGSW-D----------------FA-----------------DYELISNAFKQAA--KS----LG--H----SIEW----GGD-W------------------------------K-S-LK-----DGP----HFQLTWSEY------------------------------------------------------------------------------------------------------------------------------------------------------------- 670
 671 KKFSFSHRSENNLKGVDPRLVTIARRALVL------SEV-DFGITEG-LRTKERQKQLFEQG-K---SM------------------------------------TMN------SRHL----------T-------GDAIDVVAY------I-------DG----KVSW-D----------------WL-----------------LYEIISRAFKQAA--AE----YG--V----TIEW----GGD-W------------------------------E-K-LK-----DGV----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 671
 672 --FKLSQRSKDRLVGVHPDLVKVVHRALEL------TPV-DFGITEG-VRSLATQKKYVAEG-K---SK------------------------------------TMK------SRHL----------H-------GFAVDVVAY------P-------KD----KDTW-N----------------MK-----------------YYRMIADAFKQAG--RE----LG--V----PVEW----GGD-W------------------------------V-S-FK-----DGP----HLQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 672
 673 --FKLSQRSKDRLVGVHPDLVKVVHRALEL------TPV-DFGITEG-VRSLETQKKYVAEG-K---SK------------------------------------TMK------SRHL----------H-------GFAVDVVAY------P-------KD----KDTW-N----------------MK-----------------YYRMIADAFKQAG--RE----LG--V----PVEW----GGD-W------------------------------T-S-FK-----DGP----HLQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 673
 674 -----------------PDLVKVVHRALEL------TPV-DFGITEG-VRSLETQKKYVAEG-K---SK------------------------------------TMK------SRHL----------H-------GFAVDVVAY------P-------KD----KDTW-N----------------MK-----------------YYRMIADAFKQAG--RE----LG--V----PVIC----GVD-W------------------------------V-T-FK-----DGP----HMELDKKVY------------------------------------------------------------------------------------------------------------------------------------------------------------- 674
 675 ------------------------------------------SITEG-LRTMARQRDLVRGG-Q---SQ------------------------------------TLK------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-E----------------WD-----------------YYAQIAVAVRRAA--RE----CA--V----NVEW----GGE-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 675
 676 ----FTARSEANLIGVHPDLVRVIRLALHY------SLV-PFSITEG-LRTMARQRDLVRGG-Q---SQ------------------------------------TLK------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-E----------------WD-----------------YYAQIAVAVRRAA--RE----CA--V----NVEW----GGE-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 676
 677 ---RFTARSETNLMDVHPDLVRVMRLALYY------SLV-PFSITEG-RRSMARQRDLVRGG-Q---SQ------------------------------------TLK------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-E----------------WD-----------------YYAQIAVAVRRAA--RE----CA--V----AVEW----GGE-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 677
 678 ----FTARSEENLIGVHPDLVRVMRLALNY------SLV-PFSISEG-VRSMARQRDMLRTG-K---SQ------------------------------------TLR------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-E----------------WD-----------------YYAQIAVAVRRAA--RE----CA--V----SVEW----GGE-W------------------------------R-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 678
 679 -------------------------------------------ISEG-VRSMARQRDMLRTG-K---SQ------------------------------------TLR------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-E----------------WD-----------------YYAQIAVAVRRAA--RE----CA--V----SVEW----GGE-W------------------------------R-T-LK-----DGP----HFQLSFKDY------------------------------------------------------------------------------------------------------------------------------------------------------------- 679
 680 ----FTARSEENLIGVHPDLVRVMRLALNY------SLV-PFSISEG-VRSMARQRDMLRTG-K---SQ------------------------------------TLR------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-E----------------WD-----------------YYAQIAVAVRRAA--RE----CA--V----SVEW----GGE-W------------------------------R-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 680
 681 ----FTARSEENLIGVHPDLVRVMRLALNY------SLV-PFSISEG-VRSMARQRDMLRTG-K---SQ------------------------------------TLR------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-E----------------WD-----------------YYAQIAVAVRRAA--RE----CA--V----SVEW----GGE-W------------------------------R-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 681
 682 -------------------------------------------VSEG-LRSMARQREMVRAG-S---SQ------------------------------------TLR------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-E----------------WD-----------------YYAQIAVAVRRAA--RE----CG--I----NVEW----GGE-W------------------------------K-T-LK-----DGP----HFQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 682
 683 -------------------------------------------VSEG-LRSMARQREMVRAG-S---SQ------------------------------------TLR------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-E----------------WD-----------------YYAQIAVAVRRAA--RE----CG--I----NVEW----GGE-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 683
 684 -------------------------------------------VSEG-LRSMARQREMVRAG-S---SQ------------------------------------TLR------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-E----------------WD-----------------YYAQIAVAVRRAA--RE----CG--I----NVEW----GGE-W------------------------------K-T-LK-----DGP----HFQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 684
 685 -------------------------------------------VSEG-LRSMARQREMVRAG-S---SQ------------------------------------TLR------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-E----------------WD-----------------YYAQIAVAVRRAA--RE----CG--I----IVEW----GGE-W------------------------------K-T-LK-----DGP----HFQLT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 685
 686 -------------------------------------------VSEG-LRSMARQREMVRAG-S---SQ------------------------------------TLR------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-E----------------WD-----------------YYAQIAVAVRRAA--RE----CG--V----NVEW----GGE-W------------------------------K-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 686
 687 -------------------------------------------VSEG-LRSMARQREMVRAG-N---SQ------------------------------------TLR------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-E----------------WD-----------------YYAQIAVAVRRAA--RE----CG--I----NVEW----GGE-W------------------------------K-T-LK-----DGP----HFQLP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 687
 688 -------------------------------------------ITEG-RRNIERQRELVRTG-K---SQ------------------------------------TLN------SRHL----------T-------GHAVDVVAM------P-------AG----VVSW-Q----------------WD-----------------YYAQIAVAVRRAA--RE----LG--I----QVEW----GGA-W------------------------------Q-S-LR-----DGP----HFQLAVKDY------------------------------------------------------------------------------------------------------------------------------------------------------------- 688
 689 --FYLGKRSKSRLVGLHPDLVKVIERAIQI------TPI-DFTVLEG-LRSIERQKELYKAR-K---SK------------------------------------TMR------SRHL----------T-------GHAVDLGAL------I-------NG----AITW-E----------------TR-----------------YYQILADAVKQAA--EE----LG--I----PIEW----GGD-F------------------------------N-G-FF-----DGP----HYQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 689
 690 ---------------------EVMRKALKL------SPV-DFGISEG-VRNQKRQLELLALG-K---SL------------------------------------TSK------SRHL----------T-------GHAVDVFAV------I-------NG----TVSW-D----------------FK-----------------HYQTIATAVFQAA--KE----LS--V----DIEW----GGN-W------------------------------T-E-IK-----DGV----HFQLS----------------------------------------------------------------------------------------------------------------------------------------------------------------- 690
 691 --------------------------------------I-DFGISEG-LRNQKRQLELLASG-K---SL------------------------------------TSK------SRHL----------T-------GHAVDIFAV------I-------NG----TASW-E----------------FK-----------------HYQTIATTVFQAA--KE----LA--I----DVEW----GGN-W------------------------------A-E-IK-----DGV----HFQLSRKMY------------------------------------------------------------------------------------------------------------------------------------------------------------- 691
 692 --FQLSARDRQRLAGVYPDLAAVVEAAAGA------YNG-RFTVLEG-ARSAQRQSRLLAQG-V---SQ------------------------------------TLR------SLHI----------PQPDGW--AHAVDLAPL------V-------EG----TIPWED----------------WA-----------------SFKRLAEVMKESA--AR----LE--I----PLEW----GGD-W------------------------------T-T-LK-----DGP----HFQLPRGW-------------------------------------------------------------------------------------------------------------------------------------------------------------- 692
 693 -------------------------AAAGA------YNG-RFTVLEG-ARSAQRQSRLLAQG-V---SQ------------------------------------TLR------SLYI----------PQPDGW--AHAVDLAPL------V-------EG----TISWED----------------WA-----------------SFKRLAEVMKESA--AR----LE--I----PLGW----GGD-W------------------------------T-T-LK-----DGP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 693
 694 --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SFKRLAEVMKQSA--AR----LE--V----PLEW----GGD-W------------------------------T-T-LK-----DGP----HFQLPR---------------------------------------------------------------------------------------------------------------------------------------------------------------- 694
 695 ---------------------RVVQRAAQD------SPM-PFVVLEG-LRTRERQAQLLRQG-A---TK------------------------------------TMN------SRHI----------T-------GHAVDLAPLND----L-------DGDGDLDISWR-----------------WP-----------------HYFELAKHIKAAA--ML----EG--I----EIEW----GGD-W------------------------------R-E-FK-----DGP----HWQLT----------------------------------------------------------------------------------------------------------------------------------------------------------------- 695
 696 ------------------------------------------VVFEG-VRSLERERSLIARG-K---TA------------------------------------LKNPFR---CRHVPTKD------ARHGLV--AHAVDLVPI------V-------DG----RPQW-L----------------WP-----------------QIYPIARAMKAAA--LS----EH--V----TVEW----GGD-W------------------------------R-T-FK-----DGP----HFQLPWSLY------------------------------------------------------------------------------------------------------------------------------------------------------------- 696
 697 --------------------------------------F-DFGITSG-KRTAKQQNALFKKG-A---SQ------------------------------------LDGYSK--ISRHQ----------T-------GHAVDFVVY------------DEDG----KVTW-G----------------FS-----------------YYEQVSWAFKQAA--RE----LG--V----SIIW----GGD-W------------------------------A-S-FK-----DGP----HVELN----------------------------------------------------------------------------------------------------------------------------------------------------------------- 697
 698 --------------------------------------F-DFGITCG-LRTAEQQNALFKKG-A---SQ------------------------------------LDGYAK--ISRHQ----------T-------GHAVDFVVY------------DENG----KVTW-G----------------FS-----------------YYEQVSWAFKQAA--RE----LG--V----SIVW----GGD-W------------------------------T-S-FK-----DGP----HVELN----------------------------------------------------------------------------------------------------------------------------------------------------------------- 698
 699 ------ARSEARMVGVHTDLKAVVRRAIEL------SPF-DFGITSG-KRTAEQQNALFKKG-A---SQ------------------------------------LDGYSK--LSRHQ----------T-------GHAVDFVVY------------DENN----KVTW-G----------------FS-----------------YYEQVSWAFKQAA--RE----LD--V----PIKW----GGD-W------------------------------K-S-FK-----DGP----HVELD----------------------------------------------------------------------------------------------------------------------------------------------------------------- 699
 700 ----LSARSEARMGGVHRDLKAVVHRAIQL------SPF-DFGITSG-KRTAEEQNVLFKKG-A---SQ------------------------------------LDGYSR--KSRHQ----------T-------GHAIDFVVY------------DENG----KVTW-G----------------FS-----------------YYEQVSWAFKQAA--RE----LG--V----PIKW----GGD-W------------------------------K-S-FK-----DGP----HIEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 700
 701 --FALSARSEMRMVGVRGDLKRVVRRAIEL------TPF-DFGITSG-KRTAEEQNALFKQG-A---SQ------------------------------------LDGYSK--KSRHQ----------S-------GCAVDFVVY------------DENG----KVTW-G----------------FS-----------------YYEQVSWAFKQAA--DE----LG--I----PIVW----GGD-W------------------------------V-S-FK-----DGP----HIEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 701
 702 -----SARSEARMMGVKTELKEVVRLALTY------SRY-DFGITSG-VRTAKEQNELYLKN-A---SQ------------------------------------LDGYQR--KSKHQ----------T-------GDAIDFVAY------------DENG----RVTW-D----------------FR-----------------YYEAIADAFKRAA--SE----LK--T----PIVW----GGD-W------------------------------R-T-FK-----DGP----HIEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 702
 703 -KFIFSQRSKNNLSGVNPLLVKIAYRALDI------STA-DFAVIEG-VRTLKKQKENVKKG-V---SK------------------------------------TLN------SRHL----------T-------GDAIDILPSAI----KP------------GMEW-H----------------PH-----------------FFEPVLMAFKQAA--DE----EG--V----TLRF----GKN-WKSDPSLPV----------------------E-TRFP-----DYP----HIEIP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 703
 704 -KFKFSQRSEKNLNGVNPDLVKVIRRALEI------TPV-DFIVIEG-VRTQARQKDMVATG-K---SQ------------------------------------TMN------SRHL----------S-------GNAVDIIPVNT----TW------------KIEE--------------------------------------FKPLLKAVKQAA--DE----QG--M----KLRF----GIN-WKHDPSLPI----------------------E-TKFI-----DAP----HVEIP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 704
 705 -KFKFSQRSEKNLNGVNPDLVKVIRRALEI------TPV-DFIVIEG-VRTQARQKDMVATG-K---SQ------------------------------------TMN------SRHL----------S-------GNAVDIIPVNT----TC------------KIEE--------------------------------------FKPLLKAVKQAA--DE----QG--M----KLRF----GIN-WKHDPSLPI----------------------E-TKFI-----DAP----HVEIP----------------------------------------------------------------------------------------------------------------------------------------------------------------- 705
 706 --FKLSQRSENNLKGIHPDLVAVVRRALAL------SPV-DFTVIEG-LRTLERQTQLVAEK-K---SR------------------------------------TMN------SRHL----------T-------GHAVDLLPV--------------------GADWND----------------YT-----------------CWLPVLNAMRQAG--EE----RG--I----KLRF----GIT-WTNNPNDKP----------------------A-K-FL-----DAP----HIEI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 706
 707 -------------------------------------------ITEG-IRTLKRQKELVAQG-K---SK------------------------------------TLK------SYHL----------K-------GKAVDIAVW------I-------NG----KVTW-D----------------FK-----------------YYKEVADCVKEVA--RK----LG--Y----IITW----GGD-W------------------------------K-T-FK-----DGP----HFQIE----------------------------------------------------------------------------------------------------------------------------------------------------------------- 707
 708 ------NRSLNNLKGVDMKLVDLMTEVLQK------SPY-DFGIAEG-LRTIEKQKEYVRTG-K---SQ------------------------------------TMN------SYHL----------K-------GKAVDIKVY------K-------DG----EVTW-D----------------LK-----------------YYKEIADLVKRIA--AE----KG--L----KITW----GGD-W------------------------------K-T-LV-----DGP----HFQIE----------------------------------------------------------------------------------------------------------------------------------------------------------------- 708
 709 ----------------------------------------------GGKRTAQQQNNLFHKRPK----------------------------------------VTQLDGFKKKSYHQ---------------S--GKAVDIFIY-----------------DEHGACWNCISKYKDVAKIMKAEFLLM--------------------------------KEEGKFKGENL------EW----GGD-W--------------------------------TRFK-----DYP----HFQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 709
 710 ----------------------------------------------GGKRTAQQQNNLFHKRPK----------------------------------------VTQLDGFKKKSYHQ---------------S--GKAVDIFIY-----------------DEHGACWNCISKYKDVAKIMKAEFLLM--------------------------------KEEGKFKGENL------EW----GGD-W--------------------------------TRFK-----DYP----HFQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 710
 711 ----------------------------------------------GGKRTAQQQNNLFHKRPK----------------------------------------VTQLDGFKKKSYHQ---------------S--GKAVDIFIY-----------------DEHGACWNCISKYKDVAKIMKAEFLLM--------------------------------KEEGKFKGENL------EW----GGD-W--------------------------------TRFK-----DYP----HFQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 711
 712 --------------------RDVVRLAITRTTV-------DFGVIQG-GRTLDEQMRLYGKGRNAAECA--------------------------------KMGVPAAYAKPKESKVTWVNPRNGNHVVDGSGF--GRAVDLAPY-------------IQGK----LEWDN------------------------------DGKLGLYPKIAEAMFSAA--NE----LG-I-----QIVW----GGN-W------------------------------K-S-TP-----DRP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 712
 713 --FALGAKSLAELNGVHPDLVRVVKRAIQITAQ-------DFGVHDG-LRTEAEQR---AY-------V--------------------------------KAGVSQTMNSMHRPQ--------------ADGF--GHAVDLVPY-------------INGK----LRWE----------------------------------WPAIYPIAAAVWQAA--KD----EG-V-----PLRW----GGA-WIDMRDIKGGTPAAMKAAVDAYGARQRAKGRK-A-FT-----DGP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 713
 714 --FKFSQRSLDRLKGVHPDLVRVTHRALEL------SPY-DFTITEG-LRSLEQSAKNIANG-T---SF------------------------------------LKDPSK---SKHV----------Q-------GRAVDFAPL------K-------DG----KIDWND----------------LE-----------------SFKLVADAFFKAA--EE----LG--V----KIRW----GGD-WNQNGSYKDEI--------------------Q-RGTF-----DGP----HIELV----------------------------------------------------------------------------------------------------------------------------------------------------------------- 714
 715 --FKFGKNSEKQLATVKPELQKVARRALEL------SPY-DFTIVQG-IRTVAQSAQNIANG-T---SF------------------------------------LKDPSK---SKHI----------T-------GDAIDFAPY------I-------NG----KIDWND----------------LE-----------------AFWAVKKAFEQAG--KE----LG--I----KLRF----GAD-WNASGDYHDEI--------------------K-RGTY-----DGG----HVELV----------------------------------------------------------------------------------------------------------------------------------------------------------------- 715
 716 ---------YKASKRSKENLKGVDERLVLLVGYALAISKVDFVVVEG-LRSTERQKQLYREK------------------------------------------KSKCDGVTNISKHQ---------------E--GKAIDVYYV----------------------GWKN--------TDSSKDDRWK------------------------KLIETF--KLAGKKLG--LKLTFGYDW----G---W-----------------------------------------DNP----HIEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 716
 717 --------------------------------------EGDFFVNEG-LRTVEKQQEYYRKG------------------------------------------TTKLDGINKKSNHQ---------------L--GRAVDIYYT----------------------GWTN--------KDKEDDSRWL------------------------PIIEAF--RKAGEMLG--IKLELGYDW----G---W-----------------------------------------DRP----HIEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 717
 718 ----------------------------------------DIVITEG-LRTAETQMEYYSYG-R---TK------------------------FINKWGQKTGIITKCDGIKLKSQHQ----------AHDDEY--SHAIDFAF---------------SGETKGKLDFSA--------------------------------------KKYYEIRKIA--EP----LMQKY----NIEW----GGD-W------------------------------K-T-FK-----DMP----HWQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 718
 719 ----------------------IMEEAIKD------SPV-DFTITEG-VRTAKTQQEYYSWG-R---TK----RNPNTGNMTKVT----------------Y---ADGVIR--KSNHQ----------VKADGY--GHAVDLY---------------------------------------------PFFEGKVQVNHKDTLL--KLNLIAGHIKATA--KR----LG--I----NIVW----GGD-W------------------------------R-K-PY-----DPP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 719
 720 ------------------NLVKLMQEAIKD------SPV-DFTITEG-VRTAKAQQEYYSWG-R---TK----KNPHTGKMTKVT----------------Y---ADGVKR--KSNHQ----------VKADGY--GYAVDLY---------------------------------------------PFIDDKVQTRGDDVIP--ALKEISDHIKATA--KR----LG--I----NIVW----GGD-W------------------------------R-K-PY-----DPP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 720
 721 --YKFGSRSLNNLKGVHPNMVRLMNESIKD------SPY-DFTITEG-LRTAKRQNELYQQG-R---AK----PGI------KVT----------------S---LDGYNK--KSNHQ----------AKSDAY--GYAVDLY---------------------------------------------PYINGSVRVEYERYKK--ETNAIAEHILSTA--KR----LG--I----KVEC----GGY-W------------------------------K-S-PF-----DPP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 721
 722 ----------------------LIKESITN------SPV-DFTVVEG-VRTLKRQQELFAQG-R---TR----PGK------RVT----------------N---ADGVRN--KSNHQ----------VKPDGF--GHAVDIY---------------------------------------------PFFLGQVQVNHRDTIK--NLKLISDHIKATA--KR----LE--I----PITW----GGD-W------------------------------R-R-PY-----DPP----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 722
 723 -----------------------------D------SPV-DFTVVEG-LRTTARQQALFAQG-R---TQ----PGP------RVT----------------N---VDGIRR--RSNHQ----------AKPDGF--GHAVDIY---------------------------------------------PYFLGQVQVNHKDTIK--NLRLIAGHIKKVA--RS----LN--L----EISW----GGD-W------------------------------R-S-FY-----DPP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 723
 724 ------------LDKIHPNLVKIMKCAITN------SPV-DFTIIEG-VRTLKRQQDLYAQG-R---AK----PGI------KVT----------------N---ADGIRN--KSNHQ----------VKKDGY--GYAVDLY---------------------------------------------PFFNGKVQVNHPDTLK--KLKLIADHIKKVA--KE----LE--V----NIIW----GGD-W------------------------------K-Q-LY-----DPA----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 724
 725 ------------MEKVHPKLVEVMKTAIEN------SPY-DFRITSG-ARTTEEQKALFALG-R---TK----PGE------IVT----------------Y---ANGVTS--KSNHQ----------IKSDGF--GHAVDIFLTG--------------------VYENG-----------------SYRKFSEQEGYDV--K--RLKDVADHILAVA--KS----KN--I----NVGW----GGN-W------------------------------K-K--K-----DTP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 725
 726 -------------------------------------------ITSG-ARTTEEQKALFALG-R---TK----PGE------IVT----------------Y---ANGVTS--KSNHQ----------IKSDGF--GHAVDIFPCG--------------------VVENG-----------------VYRKFTSEEGYDE--K--KLKLIANHILAVA--KS----KN--I----NIEW----GGN-W------------------------------K-M--K-----DTP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 726
 727 ------------------KLVEVMKTAITD------SPY-DFRITDG-ARTTEEQFALYQIG-R---NK----PGR------IVT----------------N---CDGKKA--KSNHQ----------IKADGY--GHAVDIFPCG--------------------VIENG-----------------VYRKFTSEEGYDE--K--KLKLIANHILAVA--KS----KN--I----NIEW----GGN-W------------------------------K-M--N-----DTP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 727
 728 ------------------KLIEVMKEAIKN------SPF-DFRITDG-ARTAEEQFALYQKG-R---TK----PGP------KVT----------------N---CDGYKA--KSNHQ----------IKSDGY--GHAVDIFPCG--------------------IEENG-----------------EYRKFTSEEGYDD--K--KLKIISEHILKIA--KE----RG--A----NVEW----GGN-W------------------------------K-M--H-----DTP----HFEI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 728
 729 -------------------------------------------ITDG-VRTATEQNKLYQSG-R---TI----PGP------WKT----------------N---CDGYKK--ISNHQ----------TKIDGL--GYAVDIGVLV---------KE-HGR----I-------------------------------VYKGDWK--DFHYYQD-IYNTA--KK----TG--LIEKYGIEW----GGT-W------------------------------K-N-RK-----DGP----HFQISGA--------------------------------------------------------------------------------------------------------------------------------------------------------------- 729
 730 -------------------------------------------ITDG-VRTATEQNKLYQSG-R---TI----PGP------WKT----------------N---CDGYKK--ISNHQ----------TKIDGL--GYAVDIGVLI---------KEKNGK----I-------------------------------VYKGDWK--DFHYYQD-IYNTA--KK----VG--LIEKYSIEW----GGT-W------------------------------K-N-RK-----DGP----HFQILGA--------------------------------------------------------------------------------------------------------------------------------------------------------------- 730
 731 ----------------------------------------------G-MRTAEEQNKLYQYG-R---TI----PGT------WRT----------------N---CDGYKV--QSNHQ----------EKIDGL--GYAIDIGVLV---------KEKTKK----IVVENG----------------KKVEKEVEKTVYKAGPQ--DFHYYKD-IYETA--KK----HG--LIDKYNIEW----GGE-W------------------------------K---KV-----DAV----HFQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 731
 732 ----------------------------------------NFKITAG-VRTAEEQNRLYQKG-R---TA----PGS------KVT----------------N---VDGYKL--KSNHQ----------IKFDGL--GYAADIGVIV---------NG----------------------------------------EYKGTWK--DFHYYQD-IYNTA--KN----AG--LLEKYSIEW----GGNCW------------------------------R-T-FK-----DAP----HWQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 732
 733 ----------------------------------------NFKITAG-VRTAEEQNRLYQKG-R---TA----PGA------KVT----------------K---VDGYRL--KSNHQ----------IKFDGL--GYAADIGVIV---------NG----------------------------------------EYKGSWK--DFHYYQD-IYNVA--KE----KG--LLEKYGIEW----GGNCW------------------------------K-L-FK-----DAP----HWQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 733
 734 ---------------------NFIKELIKE------SPY-DFKITCG-VRTAEEQNHEYQKG-R---TILYDSNGN------KQP----------------KVSWCDGYKL--KSKHQ----------VKIDGY--GYAVDIAVLEK----E------------------------------------KYTDKKTGEEKEKTVARWDYKYYKA-IYDVA--KS----KG--LIDKYNIVW----GGN-W------------------------------K-Q--K-----DSV----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 734
 735 ---------------------NFMKELIKE------SPY-DFKITCG-VRTAEEQNREYQKG-R---TILFDENGK------KQP----------------KVSWCDGYKY--KSKHQ----------VKVDGY--GYAIDIAVLEK----E------------------------------------KYTDKKTGEEKEKTVAKWDYKYYKA-IYDVA--KS----KG--LIDKYGIVW----GGN-W------------------------------K-Q--K-----DSV----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 735
 736 -----------------------MEELIKE------SPY-DFKITCG-LRTAEEQNHEYQKG-R---TLLYDSNGN------KLS----------------KVSWCDGYKL--KSKHQ----------MKADGY--GYAVDIAVLEK----E------------------------------------KYTDKKTGEEKEKTVARWDYKYYKA-IYDVA--KS----KG--LIDKYGIVW----GGN-W------------------------------K-Q--K-----DLV----HFQL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 736
 737 --YKFSKRSLNNLEGLHPKLQEFATELIKV------TPY-DISITCG-VRTAEEQNKIYQQG-R---TI----PGK------IVT----------------K---CDGYKI--KSKHQ----------VKADGL--GYAFDIAVIID----N------------------------------------K--------------SNWNKKVFKD-VADSA--RE--------LMKKYNIEW----GGD-W------------------------------K-N-FS-----DYP----HFQY------------------------------------------------------------------------------------------------------------------------------------------------------------------ 737
 738 ---------------IHPQLAEFMKELIKI------SPY-DFKITQG-VRTAEYQNALYQQG-R---TK----PGP------KVT----------------N---CDGHIY--KSNHQ----------VKSDGL--GYAVDIAILVY----KFVKDQKTGK----V-------------------------------VKQLDWN--G-KYYNE-VYEFA--KK----YG--LLEKYGVEW----GGNCF------------------------------R-N-FI-----DKP----HWQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 738
 739 ------------------KLIELMKKAISN------SPY-DFKIVQG-LRTAEYQNELYQQG-R---TR----PGK------IVT----------------K---LDGYNR--KSNHQ----------AKADGY--GHAVDIAVCG--------------------YYDGN----------------GSYVKSTTDAEMFDN-K--KLVEISKHIKAVA--KD----MG--L----EIVW----GGD-W------------------------------K-T-LY-----DTP----HYEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 739
 740 -----------------------------S------SPF-PFMITEG-LRSMERQKQLFQEG-K---TK------------------------------------TLD------SYHL----------K-------GRAVDIAII------V-------EN----HITW-N----------------YS-----------------FYEKVAKHILKIA--HR----KH--L----KITW----GGT-W------------------------------N-T-LV-----DAC----HFQLE----------------------------------------------------------------------------------------------------------------------------------------------------------------- 740
 741 -----------------------------S------SPF-PFMITEG-LRSMERQKQLFQEG-K---TK------------------------------------TLD------SYHL----------K-------GRAVDIAVI------V-------EK----HITW-N----------------YS-----------------FYEKVAKHILKIA--HR----KH--L----KITW----GGT-W------------------------------S-T-LV-----DAC----HFQLE----------------------------------------------------------------------------------------------------------------------------------------------------------------- 741
 742 -----------------------------S------SPF-PFVITEG-CRSLERQKQLLKEK-K---TR------------------------------------TLQ------SYHL----------T-------GHAVDIAIK------V-------GE----KITW-E----------------YR-----------------YYEAVAKHIQKIA--HR----QH--I----LITW----GGT-W------------------------------K-N-LV-----DAC----HFQLE----------------------------------------------------------------------------------------------------------------------------------------------------------------- 742
 743 -----------------------------S------SPF-PFVITEG-CRSLERQKQLLKEK-K---TR------------------------------------TLQ------SYHL----------T-------GHAVDIAIK------V-------GE----KITW-E----------------YR-----------------YYEAVAKHIQKIA--HR----QH--I----LITW----GGT-W------------------------------K-N-LV-----DAC----HFQLE----------------------------------------------------------------------------------------------------------------------------------------------------------------- 743
 744 -----------------------------------------VYVFES-RRSWARQAKLYAA-------C--------------------------------KAGTGSCPAAPPGSS--------------AHQY--GRALD-----------------VNG------------------------------------------------------FSAV--KDRKQIES-VLVNHSGIEW----GVD-W------------------------------K-Q--S-----DPP----HFQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 744
 745 --------------------------------S-------NVRVFES-RRSWARQAKLYAA-------C--------------------------------KAGTGSCPAAPPGSS--------------AHQY--GRALD-----------------ING------------------------------------------------------FSAV--RDRKTIES-VLAKHPDIEW----GID-W------------------------------K-A--T-----DPP----HFQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 745
 746 ----------------------------AV------TPV-DFIVTEG-FRGREAQEEAYANG-F---SK------------------------------------ARWGKS--PHNHE----------P-------SLALDVVPY--------------------PVDWDD----------------VA-----------------KFKAIAAAFKQAA--GE----LG--V----VLRW----GGD-F------------------------------K-S-IL-----DTP----HFEI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 746
 747 ----LSKKSIQKLNTCHSDLKRLIKTVALEE---------KCAVICG-FRGRYEQEKAYYDG--------------------------------------------KSKAKWGMSKHN---------------LKPSQAVDVVPL--------------------PLDWNN---------------------------------IERFEKLGRKIMQKA--DE----LNINI------KW----GRD-F--------------------------------KGLK-----DYP----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 747
 748 ---------ERSLQKLRPEFRILVERFIESCKT---AGI-EVLIYNT-YRRKEEQYALYLQG-RAPLEV---------------VNNARKKAGMPPISEKENKVVTMLKD----SPHC---------------H--GLAVDFVPL-------------IDGK----AVWNN-------------YTLWH------------------------KCGKIA--ES----LG--I------EW----GGS-W------------------------------K-D-FP-----DHP----HLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 748
 749 -----------NLEKLETSFKKLVYKFLSECQR---QGI-QVKIYNT-LRTKEEQYALYLQG-RAPLEV---------------VNEARKRAKLKPITQSENKIVTYLKN----SPHC---------------Y--GLAFDFVPI-------------INGK----VVWNN-------------DKIWE------------------------KCGKIA--ET----FG--L------EW----GGR-W------------------------------K-N-FP-----DKP----HIQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 749
 750 -------RLEIGLSNLNYQFRRYVEKFVMECSK---EGI-SVWIYNT-YRSRAVQNALYAQG-REPLEVVNLLRQKAKLEPIDER------------------KNRYVVTKLRVSAHN---------------Y--GLAADFVPV-------------VDG----KPQW-------------------------------------YNDELWLRCGYIA--LN----LG--M------EW----GGM-W------------------------------K-G-LV-----DKP----HIQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 750
 751 --------------------------------D---NGI-EVLIYET-IRTVEQQREYVRKG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVPI------------QSNG----TEDWNG-----------------------------------YNKEPWASAIRYA--KQ----IG--F------EW----GGD-W------------------------------K-G-FV-----DSP----HLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 751
 752 --------------------------------D---NGI-EVLIYET-IRTVEQQREYVRKG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVPI------------QSNG----TEDWNG-----------------------------------YNKEPWASAIRYA--KQ----IG--F------EW----GGD-W------------------------------K-G-FV-----DSP----HLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 752
 753 ----YHNRNVSNLNKLADNTKAAAFKWYQYCID---NGI-EVLIYET-IRTVEQQREYVRKG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVPI------------QSNG----TEDWNG-----------------------------------YNKEPWASAIRYA--KQ----IG--F------EW----GGD-W------------------------------K-G-FV-----DSP----HLQYNYKGYGTDTFGKGAQNVVAPPT-SNDSVGIAYINGSNVNLRKGPGTRYGV---------------------------------------------------------------------------------------------------------------- 753
 754 --------------------------------D---NGI-EVLIYET-IRTVEQQREYVRKG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVPI------------QSNG----TEDWNG-----------------------------------YNKEPWASAIRYA--KQ----IG--F------EW----GGD-W------------------------------K-G-FV-----DSP----HLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 754
 755 --------------------------------D---NGI-EVLIYET-IRTVEQQREYVRKG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVPI------------QSNG----TEDWNG-----------------------------------YNKEPWASAIRYA--KQ----IG--F------EW----GGD-W------------------------------K-G-FV-----DSP----HLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 755
 756 ----YHNRNVSNLNKLADNTKAAAFKWYQYCID---NGI-EVLIYET-IRTVEQQREYVRKG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVPI------------QSNG----TEDWNG-----------------------------------YNKELWASAIRYA--KQ----IG--F------EW----GGD-W------------------------------K-G-FV-----DSP----HLQYNYKGYGTDTFGKGAQNVVAPPT-SNDSVGIAYINGSNVNLRKGPGTGYGV---------------------------------------------------------------------------------------------------------------- 756
 757 --MKYHNRNVSNLNKLADNTKAAAFKWYQYCIN---NGI-EVLIYET-IRTVEQQREYVRKG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVPI------------QSNG----TEDWNG-----------------------------------YNKEPWASAIRYA--KQ----IG--F------EW----GGD-W------------------------------K-G-FV-----DSP----HLQYNYKGYGTDTFGKGAQNVVTSPP-SNDSVGVAYINGSNVNLRKGPGTGYGVIRQLGKGESYKVFGKSNGWLNLGGDQWIYNDPSYIRYTGGNVPTSSQSSNDGVGVVTIIADVLRVRTGPGTNYGIVKNVYQGEKYQSFGYKDGWYNVGGNQWVSGEYVTFIK 757
 758 --MKYHNRNVSNLNKLADNTKAAAFKWYQYCID---NGI-EVLIYET-IRTVERQREYVRKG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVPI------------QSNG----TEDWNS-----------------------------------YNKEPWASAIRYA--KQ----IG--F------EW----GGD-W------------------------------K-G-FV-----DSP----HLQYNYKGYGTDTFGKGSQNVATPPP-TNDGVGVAYINGSNVNLRKGPGTGYGVIRQLGKGESYKVFGQSNGWLNLGGDQWIYNDPSYIRYTGGNVPATSQSSNDGVGVVTIIADVLRVRTGPGTNYGIVKNVYQGAKYQSFGYKDGWYNVGGNQWVSGEYVTFVK 758
 759 ----------------------------------------------------------------------------------------------------------------MRSYHL---------------I--GQALDFVPI------------KPNG----TEDWQG-----------------------------------YNKEPWASAIRYA--KQ----IG--F------EW----GGD-W------------------------------K-G-FV-----DSP----HLQYNYKGYGTDTFGKGAQNVSSPPP-SNDGAGVAYINGNNVNLRKGPGTGYGV---------------------------------------------------------------------------------------------------------------- 759
 760 ----YHERNVRNLNQLADNTKAAAFKWYQYCVD---NGI-EVLIYET-IRTVEQKRENVRKG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVSI------------KLNG----TEDWNG-----------------------------------YNKEPWASAIRYA--KN----IG--F------EW----GGD-W------------------------------K-G-FV-----DSP----HLQYNYKGYGTDIFGKGAQNIPSPPP-SNDNAGVAYINGNNVNLRKGPGTGYGV---------------------------------------------------------------------------------------------------------------- 760
 761 ----YHERNVRNLNQLADNTKAAAFKWYQYCVD---NGI-DVLIYET-IRTKEKQREYVNKG----------------------------------------------ASQTMKSYHI---------------V--GQALDFVPI------------KSNG----TEDWNG-----------------------------------YNKEPWASAIRYA--KQ----IG--F------EW----GGD-W------------------------------K-G-FV-----DSP----HLQYNYKGYGTDTFGKGAQNVPSPPPVSNDSARIAYINGNNVNLRKGPGTGYGV---------------------------------------------------------------------------------------------------------------- 761
 762 ----------------APNTKRAAKEWYNWCVA---NSI-DILIYET-LRTKEQQRYYVASG----------------------------------------------KSQTMRSYHL---------------V--GQALDFVPV------------VGKK----T-DWNG-----------------------------------YGRPEIQQAIAKA--KQ----IG--F------EW----GGD-W------------------------------K-G-FV-----DKP----HLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 762
 763 -------------------------------------DI-NILIYET-IRTVEMQRENVRKG----------------------------------------------ASKTMKSYHL---------------V--GQALDFVPV------------DSKG----QSDWKG-----------------------------------YDNPKIKQAIIEA--KR----LG--F------EW----GGD-W------------------------------K-S-FI-----DKP----HLQFNH---------------------------------------------------------------------------------------------------------------------------------------------------------------- 763
 764 ------------------KTREKAMQWYNYCIA---NGL-DILIYET-KRTEEQQRKYVAEG----------------------------------------------KSKTMRSYHL---------------V--GQALDFVPI-------------VNG----KADWNG-----------------------------------YDRPEIKKAIAFA--KS----LG--F------TW----GGD-W------------------------------K-T-LV-----DKP----HLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 764
 765 -----------------------AKKLMDYAEK---NKI-GVLIYET-IRSEAQQRENVRKG----------------------------------------------ASQTMKSYHL---------------V--GQALDFVP--------------TGGYSKSDTKWNG-----------------------------------YGASDIKKFIAYA--KS----IG--F------EW----GGD-W------------------------------T-G-FV-----DQP----HLQF------------------------------------------------------------------------------------------------------------------------------------------------------------------ 765
 766 MTMYYYKRNMDNINKLGDNTKAAAKKLMDYAEK---NKI-GVLIYET-IRSEAQQRENVRKG----------------------------------------------ASQTMKSYHL---------------V--GQALDFVP--------------TGGYSKSDTKWNG-----------------------------------YGASDIKKFIAYA--KS----IG--F------EW----GGD-W------------------------------T-G-FV-----DQP----HLQFNYKGYGTDTFGKKASSAPSKTTNSGIKSVGKI---------------------------------------------------------------------------------------------------------------------------------- 766
 767 ----------------------AAKKLLAYAEK---NKI-GVLIYGT-IRTEAQQRQNVNKG----------------------------------------------VSQTMKSYHL---------------V--GQALDFVP--------------TGGYSKSDTKWNG-----------------------------------YGTANIKKFIAYA--KS----IG--F------EW----GGD-W------------------------------K-G-FV-----DQP----HLQF------------------------------------------------------------------------------------------------------------------------------------------------------------------ 767
 768 MSMYYYSRNLDNINKLADNTKAAAKKLLDYAEK---NKL-GVLVYET-IRTEAQQRENVRKG----------------------------------------------ASQTMKSYHL---------------V--GQALDFVP--------------TKGYSSSAVDWNG-----------------------------------YGSSTAKKFVAYA--KK----LG--F------EW----GGD-W------------------------------K-S-FV-----DKP----HLQFNYKGYGTDTFGKKAVTPSKPKA-------------------------------------------------------------------------------------------------------------------------------------------- 768
 769 ---------------------AKATALFKYAED---NNI-EVLIYET-IRTKAQQEANVKSG----------------------------------------------ASQTMKSYHL---------------V--GQALDFVP--------------TKG---SATKWDE-----------------------------------YGRADIKKFIAKA--KA----LG--F------EW----GGD-W------------------------------T-S-FV-----DKP----HLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 769
 770 ----------------------KATALFKYAED---NNI-EVLIYET-IRTKAQQEANVASG----------------------------------------------ASQTMKSYHL---------------V--GQALDFVP--------------TKG---SATKWDE-----------------------------------YGRADIKKFIAKA--KA----LG--F------EW----GGD-W------------------------------T-S-FV-----DKP----HLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 770
 771 ----------------------KATALFKYAED---NNI-EVLIYET-IRTKAQQEANVASG----------------------------------------------ASQTMKSYHL---------------V--GQALDFVP--------------TKG---SATKWDE-----------------------------------YDRADIKKFITKA--KS----LG--F------EW----GGD-W------------------------------K-G-FV-----DKP----HLQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 771
 772 ---------------------------LKWAEQ---EKI-DVLIYET-LRSKAQQEENVRKG----------------------------------------------ASQTMKSYHL---------------V--GQALDFVP--------------AKG---TAVNWNG-----------------------------------YDEPSMKRFVAQA--KL----LG--F------QW----GGD-W------------------------------K-S-FI-----DKP----HLEYPH---------------------------------------------------------------------------------------------------------------------------------------------------------------- 772
 773 ---------------------------LDWSES---NGI-EVLIYET-IRTKEQQAANVASG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVM--------------AKG---KTVDWGA-----------------------------------YRSDKGKKFVAKA--KS----LG--F------EW----GGD-W------------------------------S-G-FV-----DNP----HLQF------------------------------------------------------------------------------------------------------------------------------------------------------------------ 773
 774 MTSYYYSRSLANVNKLADNTKAAARKLLDWSES---NGI-EVLIYET-IRTKEQQAANVASG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVM--------------AKG---KTVDWGA-----------------------------------YRSDKGKKFVAKA--KA----LG--F------EW----GGD-W------------------------------S-G-FV-----DNP----HLQFNYKGYGTDNFGKGASTSNSSKPSANTNTNSLGLVDYMNLNKLDSSFANRKKLATSYGIKNYSGTATQNTTLLAKLKAGKPHTPASSNKNTYYTENPKKIKTLVQCDLYNSVDFTEKHKTGGTFPPGTVFTISGMAKTKGGTPRLKTKSGYYLTANTKFVKKI 774
 775 MTSYYYSRSLANVNKLADNTKAAARKLLDWSES---NGI-EVLIYET-IRTKEQQAANVNSG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVM--------------AKG---KTVDWGA-----------------------------------YRSDKGKKFVAKA--KS----LG--F------EW----GGD-W------------------------------S-G-FV-----DNP----HLQFNYKGYGTDTFGKGASTSNSSKPSADTNTNSLGLVDYMNLNKLDSSFANRKKLATSYGIKNYSGTATQNTTLLAKLKAGKPHTPAS--KNTYYTENPRKVKTLVQCDLYKSVDFTTKNQTGGTFPPGTVFTISGMGKTKGGTPRLKTKSGYYLTANTKFVKKI 775
 776 MTSYYYSRSLANVNKLADNTKAAARKLLDWSES---NGI-EVLIYET-IRTKEQQSANVASG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVM--------------AKG---KTVDWGA-----------------------------------YRSDKGKKFVAKA--KS----LG--L------EW----GGD-W------------------------------S-G-FV-----DNP----HLQFNYKGYGTDTFGKGASTSNSSKPSANTNTNSLGLVDYMNMNKLDSSFANRKKLATSYGIKNYSGTASQNTTLLAKLKAGKPHTPAS--NNTYYTENPGKIKTLVQCDLYNSVDFTASHKTGGTYPPGTIFTIAGMAKTKGGTPRLKTKSGYFLTANKKFVKKI 776
 777 -------------------------------EN---NGI-EVLIYET-IRTKEQQAANVASG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVM--------------TKS---KTVDWGA-----------------------------------YRSDKGKKFVAKA--KA----LG--F------EW----GGD-W------------------------------S-G-FV-----DNP----HLQFNYKGYGTDTFGKGASTSNSPKPSANANTNSLGLVDYMNLNKLDSSFANRKKLATSYGIKNYSGTATQNTTLLAKLKAGKSHTPAS--KNTYYTENPGKVKTLVQCDLYNSVDFTTKTKTGGTFPPGTIFTITGMAKTKGGTPRLKTKSGYYLTANKKFVKKI 777
 778 -----------------------ARKLLDWAEN---SGI-EVLIYET-IRTKEQQSANVANG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVM--------------AKG---KTVDWGA-----------------------------------YRSDKGKKFVAKA--KS----LG--L------EW----GGD-W------------------------------S-G-FV-----DNP----HLQI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 778
 779 MTSYYYSRSLANVNKLADNTKAAARKLLDWAEN---SGI-EVLIYET-IRTKEQQSANVANG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVM--------------AKG---KTVDWGA-----------------------------------YRSDKGKKFVAKA--KS----LG--F------EW----GGD-W------------------------------S-G-FV-----DNP----HLQFNYKGYGTDTFGKGASTSNSSKPSA--NTNSLGLVDYMVSKKMDSSFSNRAKLAAKYGIKGYKGTASQNTTLLAKLKAGKPHTPASSNKNTYYTENPKKIKTLVQCDLYNSVDFTASHKTGGTYPPGTIFTIAGMAKTKGGTPRLKTKSGYFLTANKKFVKKI 779
 780 MTSYYYSRSLANVNKLADNTKVAARKLLDWAEN---SGI-EVLIYET-IRTKEQQSANVASG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVM--------------AKG---KTVNWGG-----------------------------------YRSANAKKFIAKA--KA----LG--F------TW----GGD-W------------------------------D-G-FV-----DNP----HLQFEYKGYGTDTFGKGASANVPAKPNTQSNS-SLGLVDYMNMNKLDSSFANRKKLASSYGIKNYTGTASQNTTLLAKLKAGKPHTPAS--KNTYYTENPGKIKTLVQCDLYNSVDFTEKHKTGGTYPAGTVFTISGMGKTKGGTPRLKTKSGYFLTANKKFVKKI 780
 781 MTSYYYSRSLANVNKLADNTKVAARKLLDWAEN---SGI-EVLIYET-IRTKEQQSANVASG----------------------------------------------ASQTMRSYHL---------------V--GQALDFVM--------------AKG---KTVNWGG-----------------------------------YRSANAKKFIAKA--KA----LG--F------TW----GGD-W------------------------------D-G-FV-----DNP----HLQFEYKGYGTDTFGKG----------------------------------------------------------------------------------------------------------------------------------------------------- 781
 782 -------------------TKKAATTLLNWAES---EGI-EVLIYET-IRTKEQQAENVKKG----------------------------------------------ASQTIKSYHL---------------T--GQALDFVP--------------AKG---STVQWDG-----------------------------------YGRAEIKNFVAKA--KS----LG--F------EW----GGD-W------------------------------K-S-FI-----DKP----HLQF------------------------------------------------------------------------------------------------------------------------------------------------------------------ 782
 783 MALYYEERSRNNIAKLAANTRKKAREWFDWCCE---NGI-EVLVYET-IRTKAQQSANVANG----------------------------------------------KSQTMRSYHI---------------V--GQAFDFVM--------------TKG---NTVNWNG-----------------------------------YNTSNAKKAIAKA--KS----LG--F------SW----GGD-W------------------------------S-G-FF-----DCP----HMQYEYKGYGTDKFTADTPTTTKNTGKQGVYARGNLN--------------------------------------------------------------------------------------------------------------------------------- 783
 784 MTMYYEERSRNNIAKLATNTRAKALEWFNWCCK---NGI-EILVYET-IRTKEQQSANVANG----------------------------------------------KSQTMRSYHI---------------V--GQAFDFVM--------------TKG---KTVDWSG-----------------------------------YKTATAKKAIAKA--KS----LG--F------SW----GGD-W------------------------------S-G-FF-----DCP----HMQYEYKGYGTDKFTADTPTTTKKTGKQGVYARGNLNI-------------------------------------------------------------------------------------------------------------------------------- 784
 785 MTMYYEERSRNNIAKLAANTRAKALEWFNWCCK---NGI-EVLVYET-IRTKEQQAANVANG----------------------------------------------KSQTMRSYHI---------------V--GQAFDFVM--------------AKG---KTVDWGG-----------------------------------YKTAKAKKVIAKA--KA----LG--F------SW----GGD-W------------------------------S-G-FV-----DCP----HMQYEYKGYGTDKFTADKLVANNKTGKQGVYARDFLNI-------------------------------------------------------------------------------------------------------------------------------- 785
 786 ----YDERNRRTLAELAPNTKAAAMKWYAFCEK---HGI-EILIYDA-MRTEAEQRANVEKG----------------------------------------------VSGTMKSYHL---------------V--GQAIDFVPA------------NPEG----KVSWNW-----------------------------------YDRDDIQKAVKEA--KR----LG--F------TW----GGD-W------------------------------W-N-FV-----DKP----HLQYDKIAYGQDKVLAGPPTTS------------------------------------------------------------------------------------------------------------------------------------------------ 786
 787 --------------------------------------------------------------------------------------------------------------RGGTSEHN---------------Y--GLAIDINPNEN----YMIN--SSGNVV------SGSFWDPNKS---------P-----------------YSIKENGDVVTAF--KK----YG--F------AW----GGNAW------------------------------K-S-SK-----DYM----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 787
 788 ------------------------------------------------------------------------------------------------------------------SEHN---------------W--GLAVDLNPNEN----AMIN--SSGEVV------AGSFWDPQKS---------P-----------------YSIPEDGDVVKAF--QK----YG--F------AW----GGNAW------------------------------K-S-SN-----DYM----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 788
 789 ------------------------------------------------------------------------------------------------------------------SQHS---------------Y--GRAVDVNPRQN----PMIR--GD-----YLDPPNTERWL-ARE------NYWP-----------------GMVHENG-AVEAF--TA----NG--F------AW----GGR-W------------------------------K-S-LK-----DYM----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 789
 790 ------------------------------------------------------------------------------------------------------------------SMHA---------------R--GWAVDLNPRLN----PYIK------GE-TMLPPRSAY---DPS--------MP-----------------GTLTADHPVVLKF--KE----LG--W------EW----GGD-W------------------------------T-S-LK-----DYM----HFEKVP---------------------------------------------------------------------------------------------------------------------------------------------------------------- 790
 791 ---------------------------------------------------------------------------------------------------------ISTSGNGSRSVHS---------------Y--GMAIDINPYNN----PAVL------ANGKVIPQGGTY---DRD--------IP-----------------GTLADTSPVVKEF--IR----LG--W------TW----GGN-W------------------------------T-S-LK-----DYM----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 791
 792 ----------------------------------------------------------------------------------------------------GGFVCRPSVGQTSFSQHA---------------Y--GLAIDINTFQN----PYVK--GDR-----VIPELARWYL-NRS------RKAP-----------------GMIHADDVVVRAF--AD----IG--W------EW----GGD-W------------------------------N-S-LK-----DYQ----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 792
 793 ------------------------------------------------------------------------------------------------------------------SNHA---------------Y--GKAIDINPIEN----PYIS--RSG----HIAHRASLPYR-IRRHKNPFHPEDR-----------------ALIAPHDPIVRIF--KS----RG--W------RW----GGD-W------------------------------H-S-IK-----DYQ----HFD------------------------------------------------------------------------------------------------------------------------------------------------------------------- 793
 794 ------------------------------------------------------------------------------------------------------------------SFHS---------------Y--GIALDLNPRENFGWVP-------RGIEKAIAPFSEQWCE-------------K-----------------YPRGLGETVVRCF--KK----AG--Y------AW----GGD-W------------------------------P-S-FR-----DPM----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 794
 795 ------------------------------------------------------------------------------------------------------------------SNHA---------------Y--GMAIDLNPMVN----PY-----VKNGR--VSPANGKLYK-ERNVSKCRGKYKK-----------------NMIHKNDKVYKIF--KK----YG--F------TW----GGD-W------------------------------S-S-PK-----DYQ----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 795
 796 ------------------------------------------------------------------------------------------------------------------SNHS---------------Y--GMAIDINPRIN----PW-----VKGNK--VSPANGKVYK-QRKTSKCKGKYKR-----------------YMIHKNDTAYKIF--KK----YG--F------SW----GGE-W------------------------------R-S-SK-----DYQ----HFEV------------------------------------------------------------------------------------------------------------------------------------------------------------------ 796
 797 ------------------------------------------------------------------------------------------------------------------SNHS---------------Y--GMAIDINPRIN----PW-----VKGNK--VSPANGKVYK-QRKTSKCKGKYKR-----------------YMIHKNDTAYKIF--KK----YG--F------SW----GGE-W------------------------------R-S-SK-----DYQ----HFEV------------------------------------------------------------------------------------------------------------------------------------------------------------------ 797
 798 ------------------------------------------------------------------------------------------------------------------SNHS---------------Y--GMAIDINPRIN----PW-----VKGNK--VSPANGKVYK-QRKTSKCKGKYKR-----------------YMIHKNDTAYKIF--KK----YG--F------SW----GGE-W------------------------------R-S-SK-----DYQ----HFEV------------------------------------------------------------------------------------------------------------------------------------------------------------------ 798
 799 ---------------------------------------------------------------------------------------------SMEDNNTYAFSVRPKTGKKSFSKHA---------------Y--GFAVDINPVQN----PYI---KNN----VIEPKNSIDYL-DRKSIR------K-----------------GMIVKGDVCYNAF--KK----RG--W------TW----GGE-W------------------------------K-S-LK-----DYQ----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 799
 800 ------------------------------------------------------------------------------------------------------------------SKHG---------------R--GLAVDINTLYN----PYHK--RLKNGKEVVEPATARPYL-DRS------KNHA-----------------YMIKKGDLCYRLF--KA----KG--F------RW----GGD-W------------------------------K-H-SK-----DYQ----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 800
 801 ------------------------------------------------------------------------------------------------------------------SKHG---------------L--GLAIDINTLYN----PYHK--YLKDGKEIVEPITAKPYL-NRN------ANFP-----------------YKIVKGDLCYRLF--KK----YG--F------KW----GGE-W------------------------------K-S-SK-----DYQ----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 801
 802 ----------------------------------------------------------IADDLLEIFQALYEAKYPIEKIKLVDEYYADDERSMADNNSSSFNFRFISHTTKI-SKHG---------------Y--GLAMDINTLYN----PYVK--TV-NGKLSIEPANAADYV-DRS------QDFP-----------------YKIDENDLAYQLF--IA----HG--F------QW----GGA-W------------------------------K-N-SK-----DYQ----HFEVPD---------------------------------------------------------------------------------------------------------------------------------------------------------------- 802
 803 ------------------------------------------------------------------------------------------------------------------SKHG---------------L--GLAIDINALYN----PYVK--RKDDGTWHIEPATAEPYAFDRE----SRTDIP-----------------YKIDHDDLAYKLF--TE----AG--F------EW----GGD-W------------------------------T-S-LK-----DYQ----HFEI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 803
 804 ------------------------------------------------------------------------------------------------------------------SKHG---------------L--GLAIDINTLYN----PYVK--RKDDGTWHIEPATAEPYAFDRE----SRTDIP-----------------YKIDHDDLAYKLF--TE----AG--F------EW----GGD-W------------------------------T-S-LK-----DYQ----HFEI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 804
 805 --------------------------------------VLHRNADGNPQRGEMVVNAAIADKAIDIFRQLYLADYRIERMVLIDNYDADDESSMRANNSSSFNFRFMTGSTTKISKHG---------------L--GLAIDINTLYN----PYVK--EKADGSWHIEPATGEPYALDRD----NRTDIP-----------------YKIDHNDLAYRLF--TE----AG--F------EW----GGD-W------------------------------I-S-LK-----DYQ----HFEI------------------------------------------------------------------------------------------------------------------------------------------------------------------ 805
 806 ------------------------------------------------------------------------------------------------------------------SNHS---------------Y--GLAVDINPLYN----PYIQ--TV-NGELHVEPANSVPYT-DRS----KA--WP-----------------YKIERGDLCFRLF--EE----HG--F------TW----GGD-W------------------------------T-E-SK-----DYQ----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 806
 807 ---------------------------------------------------------------------------------------------------------------GKLSNHA---------------Y--GFAIDINPQQN----PYVS--Y-RDGKARWSHENANDYI-DRS------TGLP-----------------HVITHEDLAFKVF--SA----HG--F------SW----GGD-W------------------------------N-N-PK-----DYQ----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 807
 808 ------------------------------------------------------------------------------------------------------------------SKHA---------------Y--GLAIDLNPFYN----PYIT--YNKDGTTNVSPEGSRIYE-DRS------SAFP-----------------YKIDENDLACKLF--KA----HG--F------RW----GGD-W------------------------------N-S-VK-----DYQ----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 808
 809 -------------------------------------------------------------------------------------FGADDEASMRANNSSAFNFRVVKGS-KKLSAHA---------------R--GLAVDINPLYN----PYVR--VMKDGTTVVQPEAGRPYA-DRE----GI--YP-----------------FRIDADDLAVKLF--KA----KG--W------SW----GGD-W------------------------------K-S-LK-----DFQ----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 809
 810 ----------------------------------------------G-FVDRNMRGTN-----K-------------------------------------------------LSEHA---------------K--GDALDINPR-----------------------------------------------NNP--------FLTHKTDLPPDISDMA--KA----RG--L------KW----GGD-W--------------------------------KTRT-----DPM----HFQVDKSVSNEQIAALQQ---------------------------------------------------------------------------------------------------------------------------------------------------- 810
 811 ---------------------------------------VVVHVTHS-FRKKGRRTANTTTPAR-------------------------------------------------YSNHF---------------I--GHAIDVN-L-----------------------------------------------ATPNGWCAALCLFDHRNPHAKCFINTL--KS----IG--L------RW----GGD-W--------------------------------RPKA-----DPV----HFD-DNYNSNRT---------------------------------------------------------------------------------------------------------------------------------------------------------- 811
 812 ------------------------------------KAF-QDMYAAG-FPVRAEDTDTYNWR--------------------------------------------SMASGRNRSHHS---------------Y--GCVVDLNWN------SNPMIGVTEGEYKPGVDPYS---------------------------------------VTTEVVAIW--KK----HG--F------YW----GGA-W------------------------------K-S-SK-----DYM----HFT------------------------------------------------------------------------------------------------------------------------------------------------------------------- 812
 813 ------------------------------------------------------------------------------------------------------------------SMHS---------------F--GLAIDIQPKRLGSKAIYWQWEAERNPQWMLVSQSNRWAP------------------------------------PEAVIKAF--EA----EG--F------VW----GGK-W--------------------------------D-LY-----DQM----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 813
 814 ------------------------------------------------------------------------------------------------------------------SYHS---------------Y--GAAIDLLPKSWGGLETYWQWAAEKNPEWWAVPYTRRFHP------------------------------------PMEVVKAF--EA----LG--F------LW----GGK-W--------------------------------M-TY-----DTM----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 814
 815 ------------------------------------------------------------------------------------------------------------------SFHA---------------Y--GVAVDLLMKAQAGMETYWQWTAAKGINWQTVPAEKRQNP------------------------------------PAPVIRAF--EE----QG--F------IW----GGR-W--------------------------------P-RY-----DTM----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 815
 816 ------------------------------RA-IRDRGI-PLTINSA-YRTIAQQLILYNHYRGGR--R--------------------------------CGIQLAARPP--RSNHQ---------------S--GLALD-----------------------------------IQ-DTDG----W-----------------------RPFL--E----R----HG--W------RW----LGP-------------------------------------R-----DYP----HFD------------------------------------------------------------------------------------------------------------------------------------------------------------------- 816
 817 --------------------------RALERA-IQDRGV-PMVINSA-YRTIAQQLVLYNHYR-NR--R--------------------------------CGIPIAARPS--RSNHQ---------------S--GLAID-----------------------------------IS-DYLS----W-----------------------RPYL--Q----K----YG--W------RW----LGW-------------------------------------G-----DPV----HFDYVGGRTRDIRSLAVRAFQRVWNRY------------------------------------------------------------------------------------------------------------------------------------------- 817
 818 ------------PARLLPFIGGPTAKARLKTA-IDNRGV-TLRVNSA-YRTFAQQYLLFREHHSGHPTK--------------------------------CGISAVARPG--TSNHE---------------S--GLALD-----------------------------------IQ-NPMT----W-----------------------RPFL--EF--SG----LG--W------RW----FGP-------------------------------------K-----DTP----HYDFV----------------------------------------------------------------------------------------------------------------------------------------------------------------- 818
 819 -----------------------------AIAECERENL-DAMVYEG-YRSQQLQAIYFARG-RTVVPP--------------------------------HHTVTNASTNL-RSWHG---------------Y--GLAVDVVHS---------------------------------------EHFWE---------------PPGGEGWFRQVAEIF--KI----HG--C------KW----GGD-W--------------------------------TN-R-----DLP----HMQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 819
 820 ---------------------------ERAIADANARGF-DAIVYEA-YRSPELQAAYYARG-RTVVPP--------------------------------EDTVTNAPTNL-FSWHG---------------Y--GLAVDVVSR---------------------------------------NHGWD---------------RP--RAWFEGVAESF--KR----EG--C------KW----GGD-W--------------------------------TK-P-----DLP----HFQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 820
 821 -----------------------------------------ALVP---------------------------------------------------------------PTNATYSNHS---------------S--GTAVDLNLE------------IHGG----QGFSGT-----------------------------------FTPEQTAKIRAKL--AS----MGGQI------VW----GGE-W------------------------------S-T-LP-----DDP----HFEV------------------------------------------------------------------------------------------------------------------------------------------------------------------ 821
 822 ------------------------KNFINRVEIE--LGY-KFRISDG-YRDFKHQAGLTT--------------------------------------------AIKAAPG--KSYHN---------------Y--GLAIDIVQI-T----N-------NGKSDSYKLLEN---------------PNN------------------------KIAKIG--KE----IG--F------EW----GGH-W------------------------------KTR--------DLP----HFEM------------------------------------------------------------------------------------------------------------------------------------------------------------------ 822
 823 --------------------FVVVALEVIARC--AARGV-RYVATHG-FRDLTEQAELRRLYLAGKGGK-------------------------------------AAPAG--LSAHN---------------Y--GLAFDFVCD-------------------------------AS-PQPGVQPDWC-------------------ESAYLVLGEES--AK----AG--L------VW----GGR-F-----------------------------------G-----DSP----HVQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 823
 824 -------------------PFVAVSLEVIARS--AAHGV-RYVATHG-FRDLPEQAELRRLYAAGKGGK-------------------------------------ASPAG--LSAHN---------------Y--GLAFDFVCD-------------------------------AS-PRPGVQPDWR-------------------ESAYRVLGDES--TK----AG--L------VW----GGR-F-----------------------------------G-----DSP----HVQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 824
 825 -------------------PFAAVAFEVISRC--EARGA-SYIATFG-SRSLEEQAELYRLYREGKGGK-------------------------------------AAPAG--LSAHN---------------Y--GLAFDFCRD-------------------------------GDRAKPGLQPDWR-------------------ASAFKELGEES--QR----AG--L------VW----GGT-F-----------------------------------A-----DAP----HVQ------------------------------------------------------------------------------------------------------------------------------------------------------------------- 825
 826 ------------------------------LNALRLRGF-QPKLFYG-WRSVAVQQELYKKG----------------------------------------------RSKVRFSFHN---------AQAPSGVPNAYAADIIDK--------------------RYAWSE---------SEETQKFWK------------------------ALGEEA--KK----AG--L------YW----GGD-W--------------------------------VNFK-----DWA----HVQFYPN--------------------------------------------------------------------------------------------------------------------------------------------------------------- 826
 827 ---------------------------------------------WG-LRSALGSGARGAPG-----------------------------------------------------------------------LQEGIWV------------------------------------------------------------------LPPYTRSVVGESS--RP----AG--L----CPTW----GL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 827
 828 ---KFSKISATRLASCHPKLQSVFTAVLEVC---------DCSILCG-HRTKEEQN-ALPST--------------------------------------------NTQVRYPNSKHN---------------SLPSKAVDATPY--------------------PYDEDD---------------------------------RERFSYFAGIVIGVG--AS----MGVAI------RW----GGD-WDKDNELKD------------------------NGFD-----DLM----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 828
 829 ---KFSKKSASRLATCHPDLITVFTRVLEIC---------DCSILCG-HRTKEEQN-ALPST--------------------------------------------NTQVRYPNSKHN---------------SLPSEAVDATPY--------------------PYDEDD---------------------------------RERFSYFAGIVMGVG--AS----MGIAI------RW----GGD-WDRDFDLKD------------------------NTFD-----DLM----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 829
 830 ---KFSKTSAARLATCHPDLIKVFTRVLELC---------DCSILCG-HRTEEEQNTAFAEG--------------------------------------------KSQVKYPNGKHN---------------TLPSRAVDVAPY--------------------PIDWND---------------------------------RERFSYFAGLVVGVG--VS----MGVAI------RW----GGD-WDKDNELKD------------------------NNFD-----DLV----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 830
 831 ---KFSETSKARLAKCDARLQEIFYAVVTKA---------DCSILEG-HRNEQKQRMMLMQG--------------------------------------------RTKLAWPNSKHN---------------RVPSLAVDVAPY--------------------PIIWDE---------------------------------RERFIYFAGFVKGIA--AA----KGIGL------RW----GGD-WDMDNSLKD------------------------NRFD-----DLV----HFEL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 831
 832 ---------------VHKNVAYAFKLMLDDAKAD------GVDLSGGGFRTRERQIELRKVN----------------------------GCPDIYTAPASSCRVPTAIPG--RSLHE---------------L--GLAIDITS---------------GGRTLTA-------------------------------------------------------GS----AG--F------KWLSANAGR-Y--------------------------------G-FV-----NLPSEPWHW-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 832
 833 -----------------------------LIHWAEEHGY-RLTFGEA-YRTPEQAALNAKKG-----------------------------------------------SGITNSLHT---------------Q--RLAVDFNLF-V------------NGQYKTNTADYL------------------------------------------PLGEYW--ES----LGGT--------W----GGR-F------------------------------K-SRP------DGN----HFSLEHNG-------------------------------------------------------------------------------------------------------------------------------------------------------------- 833
 834 ---------------LSEKQQLFTVMVANLIHWAEERGY-RLTFGEA-YRTPEQAALNAKKG-----------------------------------------------SGISNSLHT---------------Q--RLAVDFNLF-V------------NGQYQTRTEDYL------------------------------------------PLGEYW--ES----LGGS--------W----GGR-F------------------------------K-SRP------DGN----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 834
 835 ---------------LSEKQQLFTVMVANLIHWAEEHGY-RLTFGEA-YRTPEQAALNAKKG-----------------------------------------------SGITNSLHT---------------R--RLAVDFNLF-V------------NGQYQTRTEDYL------------------------------------------PLGEYW--ES----LGGS--------W----GGR-F------------------------------K-SRP------DGN----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 835
 836 ---------------LSEKQQLFTVMVANLIHWAEEHGY-RLTFGEA-YRTPEQAALNAKKG-----------------------------------------------SGITNSLHT---------------R--RLAVDFNLF-V------------NGQYQTRTEDYL------------------------------------------PLGEYW--ES----LGGS--------W----GGR-F------------------------------K-SRP------DGN----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 836
 837 ---------------LSEKQQLFTVMVANLIHWAEEKGY-RLTFGEA-YRTPEQAALNAKKG-----------------------------------------------SGISNSLHT---------------Q--RLAVDFNLF-I------------NGKYATRTEDYL------------------------------------------PLGEYW--ES----LGGS--------W----GGR-F------------------------------K-TNP------DGN----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 837
 838 -----------------------------LIHWADEHGY-RLTFGEA-YRTPEQAALNAKKG-----------------------------------------------SGISNSLHT---------------Q--RLAVDFNLF-V------------NGKYMTRTEDYR------------------------------------------PLGEFW--ES----LGGS--------W----GGR-F------------------------------K-SNP------DGN----HFSLEHNG-------------------------------------------------------------------------------------------------------------------------------------------------------------- 838
 839 -----------------------------LIQYANANGM-WLTFGEA-YRTPEQAALNAKKG-----------------------------------------------SGISNSLHT---------------L--RLAVDFNLF-V------------KGEYKTRTEDYL------------------------------------------PLGEYW--ES----LGGS--------W----GGR-F------------------------------K-SRP------DGN----HFSLEHNG-------------------------------------------------------------------------------------------------------------------------------------------------------------- 839
 840 ----------------------------QLITWANDKGY-RLTFGEA-YRTPEQAKLNAKSG-----------------------------------------------AGIANSLHT---------------Q--RLAVDFNLF-V------------NGEYKTKTEDYL------------------------------------------PLGEYW--ES----LGGA--------W----GGR-F------------------------------K-SRP------DGN----HFSLEHNG-------------------------------------------------------------------------------------------------------------------------------------------------------------- 840
 841 ---------------LSEKQQLFVQLIGQLIEWAGNHGY-RLTFGEA-YRTPEQAKLNAKSG-----------------------------------------------AGIANSLHT---------------Q--RLAMDFNLF-I------------NGQYQTSTEAYT------------------------------------------PLGEYW--ES----LGGA--------W----GGR-F------------------------------K-SRP------DGN----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 841
 842 ---------------------------------AHQRGY-GLTFGEA-YRTPEQAKLNAQKG-----------------------------------------------SGIANSLHC---------------Q--RLAVDFNLF-I------------NGEYQTRTEAYR------------------------------------------ELGEYW--ES----LGGA--------W----GGR-F------------------------------K-KRP------DGN----HFSLEH---------------------------------------------------------------------------------------------------------------------------------------------------------------- 842
 843 ---------------------------------AHQRGY-GLTFGEA-YRTPEQAKLNAQKG-----------------------------------------------SGIANSLHC---------------Q--RLAVDFNLF-I------------NGEYQTRTEAYR------------------------------------------ELGEYW--ES----LGGA--------W----GGR-F------------------------------K-KRP------DGN----HFSLEH---------------------------------------------------------------------------------------------------------------------------------------------------------------- 843
 844 ---------------------------------AHQRGY-GLTFGEA-YRTPEQAKLNAQKG-----------------------------------------------SGIANSLHC---------------Q--RLAVDFNLF-I------------NGEYQTRTEAYR------------------------------------------ELGEYW--ES----IGGA--------W----GGR-F------------------------------K-NRP------DGN----HFSLEH---------------------------------------------------------------------------------------------------------------------------------------------------------------- 844
 845 ---------------LSEKQQLFTQLVAQLIQWAGERGY-RLTFGEA-YRTPEQAKLNARNG-----------------------------------------------SGIANSLHT---------------Q--RLAVDLNLF-I------------NGEYQTRTEAYL------------------------------------------PLGEYW--ES----LGGC--------W----GGR-F------------------------------T-SRP------DGN----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 845
 846 ---------------LSEKQQLFTQLIAQLISWAGERGY-RLTLGEA-YRTPEQAKLNAKTG-----------------------------------------------SGISNSLHT---------------S--RLAVDFNLF-I------------NGVYQTKSEAYL------------------------------------------PLGEQW--EK----LGGS--------W----GGR-F------------------------------K-SNP------DGN----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 846
 847 ---------------LSEKQQLFAQLIAQLIVWAGDNGY-RLTFGEA-YRTPAQAALNARAG-----------------------------------------------TGIRNSLHT---------------Q--RLAVDFNLF-I------------NGVYQTKTEAYA------------------------------------------PLGEYW--EK----LGGT--------W----GGR-F------------------------------K-SNP------DGN----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 847
 848 ---------------LSEKQAVFTLMIAQLINWAGNHNY-RLTFGEA-WRTPEQAALNAKNG-----------------------------------------------KGIANSLHT---------------Q--RLAVDFNLF-I------------NGQYQTSTEAYK------------------------------------------PLGEYW--ES----IGGS--------W----GGR-F------------------------------K-SNP------DGN----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 848
 849 ---------------LSEKQQLFSVLIAQLILWADEHGY-RVTFGEA-YRTPEQAALNAKKG-----------------------------------------------MGIRNSLHS---------------Q--RLAVDLNLF-I------------QGTYQTSSTAYL------------------------------------------PLGEYW--ES----LGGT--------W----GGR-F--------------------------------SRP------DGN----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 849
 850 -------------------------------------------------RTEAQANLNAANG-----------------------------------------------SGISNSLHK---------------H--RLAVDFNLF-K------------DGKYLTATSDYK------------------------------------------ELGEYW--ES----LGGS--------W----GGR-F------------------------------K-TRP------DGN----HFSL------------------------------------------------------------------------------------------------------------------------------------------------------------------ 850
 851 ---------------LVDKQNTFTGMVAKLITFAQQKGY-KLTFGEA-YRTEEQAKLNAKKG-----------------------------------------------SGISNSLHT---------------Q--RLAVDFNLFDA------------NGKYLTATSDYK------------------------------------------ELGEYW--ES----LGGS--------W----GGR-F------------------------------K-TRP------DGN----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 851
 852 ---------------LSQKQQRFTVMVGQLIAWAAAHGY-GLTFGEA-YRTPEQAKLNAAAG-----------------------------------------------KGIVASLHG---------------Q--RLAVDFNLF-K------------DGVYQDKTEAYS------------------------------------------PLGEYW--ES----LGGA--------W----GGR-F------------------------------N-SRP------DGN----HF-------------------------------------------------------------------------------------------------------------------------------------------------------------------- 852
 853 ----------------------------KLIIFAQANGY-QLTFGEA-YRTKEQAALNEKAG-----------------------------------------------KGISKSLHT---------------E--RLAVDFNLF-K------------DGKWLTASSDHK------------------------------------------PLGEYW--ES----IGGS--------W----GGR-F------------------------------N----------DGN----HYSLEHNG-------------------------------------------------------------------------------------------------------------------------------------------------------------- 853
 854 -----------------------------LIIFAYDNGY-ELTFSEA-YRTPEQAALNAKSG-----------------------------------------------SGIKNSLHT---------------Q--RLAVDFNLF-K------------DGKYLTASSDHK------------------------------------------LLGEYW--ES----IGGT--------W----GGR-F------------------------------N----------DGN----HYSLEHNG-------------------------------------------------------------------------------------------------------------------------------------------------------------- 854
 855 ----------------------------KLIVYAYQHGL-ELTFGEA-YRTAEQQEIYVKAG----------------------------------------------KSKTMNSDHL---------------R--RLAVDFNVF-T------------NNKLTYDWATVK------------------------------------------ILGDYW--ET----LHPSN------RW----GGD-W------------------------------N-KNNIKDGFIDVP----HFEMH----------------------------------------------------------------------------------------------------------------------------------------------------------------- 855
 856 -----------------------------------DNGY-AVRIGEV-ERTQAQQEIYIKEG----------------------------------------------KSRTSNSMHL---------------K--RCAADLHIF-K------------NGEWLQSKAQLQ------------------------------------------SIGDYW--ES----LDQSN------KW----GGN-F------------------------------K-NFI------DTP----HFE------------------------------------------------------------------------------------------------------------------------------------------------------------------- 856
 857 ---------------LGENQEAFMRDVEKLLIYLHINGY-YVRGGEL-ERTQAQQEIYYNTG----------------------------------------------KSKTMQSNHL---------------K--RCAIDLHIF-K------------NGVWLQSKQDLQ------------------------------------------EIGNYW--ES----LNSLN------RW----GGN-F------------------------------T-SFL------DTP----HFERN----------------------------------------------------------------------------------------------------------------------------------------------------------------- 857
 858 ---------------------AAAAFNAMSQAYAKQTGS-PICVTDS-YRSLSQQYI--TKAKRGR---------------------------------------FAARPG--TSRHG---------------L--GMALDLCGG-------------------------------IQ-NFGAPAHLWM-------------------KQNAP---------L----YG--W---FHPSW----AGP-M--------------------------------QATP-----EPW----HWEF------------------------------------------------------------------------------------------------------------------------------------------------------------------ 858
 859 --------------------------------STKEEFMTDYRLYIELLRNLADEAGLPKTLDTGSLAG----------------------------------IKTHEYCTNNQPNNH------------------SDHVDPYPY----------------------------------------------------------------------------------LA---------KW----GIS--------------------------------R-EQFK-------------YDIENGLT------------------------------------------------------------------------------------------------------------------------------------------------------------- 859