Activity |
Catalytic type | Cysteine |
Peplist | Included in the Peplist with identifier PL00050 |
NC-IUBMB | Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.22 (Cysteine endopeptidases) >> Peptidase 3.4.22.32
|
Enzymology | BRENDA database |
Biotechnology | Laboratory reagent in blood group determination. |
Pharmaceutical relevance | Bromelain may be effective for burn debridement (Rowan et al., 1990). It may also be useful to activate inflammatory response or as vaccine adjuvant (Engwerda et al.%, 2001; Engwerda et al.%, 2001). It has been suggested to be useful in the treatment of osteoarthritis (Brien et al., 2004). Bromelain has been shown to improve the decrease in defecation in postoperative rats, and it is suggested that bromelain may benefit patients with postoperative ileus (Wen et al., 2005). |
Other databases
| WIKIPEDIA | http://en.wikipedia.org/wiki/Bromelain |
Cleavage site specificity |
Explanations of how to interpret the
following cleavage site sequence logo and specificity matrix can be found here. |
Cleavage pattern | -/pl/-/--/-/-/- (based on 26 cleavages) |