$VAR1 = undef;
Summary for peptidase S09.004: acylaminoacyl-peptidase
Names | |
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MEROPS Name | acylaminoacyl-peptidase |
Other names | acylamino-acid-releasing enzyme, APEH g.p. (Homo sapiens), N-acylpeptide hydrolase, N-formylmethionine (fMet) aminopeptidase, oxidized protein hydrolase, OPH |
Domain architecture |
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MEROPS Classification | |
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Classification | Clan SC >> Subclan (none) >> Family S9 >> Subfamily C >> S09.004 |
Holotype | acylaminoacyl-peptidase (Homo sapiens), Uniprot accession P13798 (peptidase unit: 477-728), MERNUM MER0000408 |
History | Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London. |
Activity | |||
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Catalytic type | Serine | ||
Peplist | Included in the Peplist with identifier PL00369 | ||
NC-IUBMB | Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.19 (Omega peptidases) >> Peptidase 3.4.19.1 | ||
Enzymology | BRENDA database | ||
Activity status | human: active (Manning, 2004) mouse: active (Kobayashi et al., 1987) | ||
Other databases | TREEFAM | http://www.treefam.org/family/TF312937 | |
Cleavage site specificity | Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here. | ||
Cleavage pattern | -/-/-/fah-/-/-/- (based on 14 cleavages) |
Specificity matrix | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Human genetics | ||||||
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Gene symbol | Locus | Megabases | Ensembl | Entrez gene | Gene Cards | OMIM |
APEH | 3p21 | ENSG00000164062 | 327 | APEH | 102645 | |
Mouse genetics | ||||||
Gene symbol | Position | Megabases | Ensembl | Entrez gene | MGI | |
Apeh | 9:F2 | ENSMUSG00000032590 | 235606 | MGI:88041 |