Structure for peptidase A02.012: retropepsin (human T-cell leukemia virus)

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

 

PDB Organism Resolution Comment
2B7F human T-cell lymphotropic virus type 1 2.60 Å mature
The dimer is shown. The active site residue Asp32 is shown in ball-and-stick representation in pink (one for each monomer). A bound statin inhibitor is shown in grey in ball-and-stick representation.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
human T-cell lymphotropic virus type 1
mature  peptidase 2.60 Å 2B7F 2B7F 2B7F 2B7F 2B7F 2B7F Li et al., 2005
complex with the inhibitor, kni- 10562 1.96 Å 3LIN 3LIN 3LIN 3LIN 3LIN 3LIN
complex with the inhibitor, kni- 10673 2.29 Å 3LIQ 3LIQ 3LIQ 3LIQ 3LIQ 3LIQ
complex with the inhibitor kni-10681 2.19 Å 3LIT 3LIT 3LIT 3LIT 3LIT 3LIT
complex with the inhibitor kni- 10683 2.59 Å 3LIV 3LIV 3LIV 3LIV 3LIV 3LIV
complex with the inhibitor kni- 10729 2.70 Å 3LIX 3LIX 3LIX 3LIX 3LIX 3LIX
complex with statine-containing peptide inhibitor 1.86 Å 3LIY 3LIY 3LIY 3LIY 3LIY 3LIY
complex with the hiv-1 protease inhibitor indinavir 2.40 Å 3WSJ 3WSJ 3WSJ 3WSJ 3WSJ 3WSJ
complex with compound 9 2.80 Å 4YDF 4YDF 4YDF 4YDF 4YDF 4YDF