Structure for peptidase A22.001: presenilin 1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Homo sapiens
NMR structure; CTF subunit 0.00 Å 2KR6 2KR6 2KR6 2KR6 2KR6 2KR6
mature  peptidase 4.40 Å 4UIS 4UIS 4UIS 4UIS 4UIS 4UIS Sun et al., 2015
mature  peptidase 3.40 Å 5A63 5A63 5A63 5A63 5A63 5A63 Bai et al., 2015
mature  peptidase 4.20 Å 5FN2 5FN2 5FN2 5FN2 5FN2 5FN2 Bai et al., 2015
mature  peptidase 4.10 Å 5FN3 5FN3 5FN3 5FN3 5FN3 5FN3 Bai et al., 2015
mature  peptidase 4.00 Å 5FN4 5FN4 5FN4 5FN4 5FN4 5FN4 Bai et al., 2015
mature  peptidase 4.30 Å 5FN5 5FN5 5FN5 5FN5 5FN5 5FN5 Bai et al., 2015
complex with a notch fragment 2.70 Å 6IDF 6IDF 6IDF 6IDF 6IDF 6IDF
recognition of the amyloid precursor protein by human gamma-secretase 2.60 Å 6IYC 6IYC 6IYC 6IYC 6IYC 6IYC