Structure for peptidase C05.001: adenain

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

PDB Organism Resolution Comment
1AVP_A human adenovirus type 2 2.60 Å complex with peptide cofactor
Catalytic residues are shown in ball-and-stick representation: His54 in purple, Glu71 in blue and Cys122 in yellow. The peptide cofactor is shown at the bottom of the figure.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
human adenovirus D
complex with N-[(3,5-dichlorophenyl)acetyl]-L-threonyl- N-[(2Z)-2-iminoethyl]glycinamide 2.07 Å 4PIQ 4PIQ 4PIQ 4PIQ 4PIQ 4PIQ Mac et al., 2014
complex with N~2~-[(2R)-2-(3,5-dichlorophenyl)-2-(dimethylamino)acetyl]- N-(2-[(Z)-iminomethyl]pyrimidin-4-ylmethyl)- L-isoleucinamide 2.10 Å 4PIS 4PIS 4PIS 4PIS 4PIS 4PIS Mac et al., 2014
complex with a nitrile inhibitor 1.03 Å 4WX4 4WX4 4WX4 4WX4 4WX4 4WX4
crystal structure of human adenovirus 8 protease with an irreversible vinyl sulfone inhibitor 2.15 Å 4WX6 4WX6 4WX6 4WX6 4WX6 4WX6
crystal structure of adenovirus 8 protease with a nitrile inhibitor 2.40 Å 4WX7 4WX7 4WX7 4WX7 4WX7 4WX7
human adenovirus type 2
complex with peptide cofactor 2.60 Å 1AVP 1AVP 1AVP 1AVP 1AVP 1AVP Ding et al., 1996
complex with 11 amino acid cofactor 1.60 Å 1NLN 1NLN 1NLN 1NLN 1NLN 1NLN McGrath et al., 2003
mature  peptidase 0.98 Å 4EKF 4EKF 4EKF 4EKF 4EKF 4EKF Baniecki et al., 2013
complex with N-benzyl-2-[(Z)-iminomethyl]pyrimidine-5- carboxamide 1.59 Å 4PID 4PID 4PID 4PID 4PID 4PID Mac et al., 2014
complex with N-(2S)-2-(3-chlorophenyl)-2-[(methylsulfonyl)amino]acetyl- L-phenylalanyl-N-[(2Z)-2-iminoethyl]glycinamide 1.94 Å 4PIE 4PIE 4PIE 4PIE 4PIE 4PIE Mac et al., 2014
structure of human adenovirus 2 protease with cofactor pvic 2.10 Å 5FGY 5FGY 5FGY 5FGY 5FGY 5FGY