Structure for peptidase C14.009: caspase-8

PDB	Organism	Resolution	Comment
1QDU	Homo sapiens	2.80 Å	complex with tripeptide ketone inhibitor Z-Glu-Val-Asp-dichloromethylketone
One heterodimer is shown. Catalytic residues are shown in ball-and-stick representation: His317 in purple and Cys360 in yellow. The inhibitor Glu-Val-dehydroxymethylaspartic acid is shown in ball-and-stick representation in grey.

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TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Homo sapiens
complex with Z-Asp-Glu-Val-Asp-CHO inhibitor	2.90 Å	1F9E	1F9E	1F9E	1F9E	1F9E	1F9E	Blanchard et al., 2000
complex with baculovirus P35 inhibitor	3.00 Å	1I4E	1I4E	1I4E	1I4E	1I4E	1I4E	Xu et al., 2001
complex with tripeptide ketone inhibitor Z-Glu-Val-Asp-dichloromethylketone	2.80 Å	1QDU	1QDU	1QDU	1QDU	1QDU	1QDU	Blanchard et al., 1999
complex with acetyl-Ile-Glu-Thr-aspartic aldehyde	1.20 Å	1QTN	1QTN	1QTN	1QTN	1QTN	1QTN	Watt et al., 1999
complex with	1.95 Å	2C2Z	2C2Z	2C2Z	2C2Z	2C2Z	2C2Z
alternative p35-caspase-8 complex	3.00 Å	2FUN	2FUN	2FUN	2FUN	2FUN	2FUN	Lu et al., 2006
complex with darpin-8.4	1.80 Å	2Y1L	2Y1L	2Y1L	2Y1L	2Y1L	2Y1L
zymogen; complex with c-flipl	1.90 Å	3H11	3H11	3H11	3H11	3H11	3H11	Yu et al., 2009
complex with a covalent inhibitor	1.80 Å	3KJN	3KJN	3KJN	3KJN	3KJN	3KJN
complex with a covalent inhibitor	1.80 Å	3KJQ	3KJQ	3KJQ	3KJQ	3KJQ	3KJQ
caspase-3 specific unnatural amino acid-based peptides	1.18 Å	4JJ7	4JJ7	4JJ7	4JJ7	4JJ7	4JJ7
caspase-8 specific unnatural amino acid peptides	2.12 Å	4PRZ	4PRZ	4PRZ	4PRZ	4PRZ	4PRZ
caspase-8 specific unnatural amino acid peptides	1.73 Å	4PS1	4PS1	4PS1	4PS1	4PS1	4PS1