Structure for peptidase M12.005: procollagen C-peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

PDB Organism Resolution Comment
3EDG Homo sapiens 1.27 Å peptidase domain only
The catalytic and structural zinc atoms are shown as light grey CPK spheres. The zinc ligands are shown in ball-and-stick representation: His213,His217 and His223 in purple. The catalytic Glu214 is shown in blue ball-and-stick representation.
This browser does not have a Java Plug-in.
Get the latest Java Plug-in here.
Show surface
TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Homo sapiens
peptidase domain only 1.27 Å 3EDG 3EDG 3EDG 3EDG 3EDG 3EDG
complex with partially bound dimethyl sulfoxide (DMSO) 1.25 Å 3EDH 3EDH 3EDH 3EDH 3EDH 3EDH
complex with a reverse hydroxymate - compound 22 1.45 Å 6BSL 6BSL 6BSL 6BSL 6BSL 6BSL
complex with a reverse hydroxamate - compound 4 2.33 Å 6BSM 6BSM 6BSM 6BSM 6BSM 6BSM
complex with a reverse hydroxymate - compound 1 2.05 Å 6BTN 6BTN 6BTN 6BTN 6BTN 6BTN
complex with (2~s)-2-[[(1~r,3~s,4~s)-2-[(2~r)-2-[2- (oxidanylamino)-2-oxidanylidene-ethyl]heptanoyl]-2- azabicyclo[2.2.1]heptan-3-yl]carbonylamino]-2-phenyl-ethanoic acid 2.05 Å 6BTO 6BTO 6BTO 6BTO 6BTO 6BTO
complex with a hydroxamate 1.93 Å 6BTP 6BTP 6BTP 6BTP 6BTP 6BTP
complex with a hydroxamate - compound 2 1.75 Å 6BTQ 6BTQ 6BTQ 6BTQ 6BTQ 6BTQ