Structure for peptidase M34.002: Pro-Pro endopeptidase 1 (Clostridium difficile-type)

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Peptoclostridium difficile
precursor	1.40 Å	5A0P	5A0P	5A0P	5A0P	5A0P	5A0P	Schacherl et al., 2015
Glu143Ala mutant; complex with product	1.25 Å	5A0R	5A0R	5A0R	5A0R	5A0R	5A0R	Schacherl et al., 2015
Glu143Ala mutant	2.56 Å	5A0S	5A0S	5A0S	5A0S	5A0S	5A0S	Schacherl et al., 2015
Ala143Glu, Phe178Tyr mutant	1.70 Å	5A0X	5A0X	5A0X	5A0X	5A0X	5A0X	Schacherl et al., 2015
crystal structure of tce treated rppep-1	1.38 Å	5N12	5N12	5N12	5N12	5N12	5N12
crystal structure of apo ppep-1(Glu143Ala/Tyr178Phe) in complex with substratepeptide ac-evnapvp-conh2	1.39 Å	6R4W	6R4W	6R4W	6R4W	6R4W	6R4W
crystal structure of ppep-1(Glu143Ala/Tyr178Phe) in complex with substrate peptide ac-evnpavp-conh2	1.83 Å	6R4X	6R4X	6R4X	6R4X	6R4X	6R4X
crystal structure of holo ppep-1(Glu143Ala/Tyr178Phe) in complex with product peptide ac-evnp-co2 (substrate peptide: ac-evnpavp-conh2)	1.45 Å	6R4Y	6R4Y	6R4Y	6R4Y	6R4Y	6R4Y
crystal structure of holo ppep-1Glu143Ala/Tyr178Phe) in complex with product peptide ac-evnp-co2 (substrate peptide: ac-evnppvp-conh2)	1.05 Å	6R4Z	6R4Z	6R4Z	6R4Z	6R4Z	6R4Z
crystal structure of holo ppep-1Glu143Ala/Tyr178Phe) in complex with substrate peptide ac-evnapvp-conh2	1.81 Å	6R50	6R50	6R50	6R50	6R50	6R50
crystal structure of apo ppep-1(Glu143Ala/Tyr178Phe) in complex with fibrinogen-derived substrate peptide ac-slrpapp-conh2	1.94 Å	6R51	6R51	6R51	6R51	6R51	6R51
crystal structure of ppep-1(k101a)	2.02 Å	6R52	6R52	6R52	6R52	6R52	6R52
crystal structure of ppep-1(k101r)	1.80 Å	6R53	6R53	6R53	6R53	6R53	6R53
crystal structure of ppep-1(e184a)	1.42 Å	6R54	6R54	6R54	6R54	6R54	6R54
crystal structure of ppep-1(e184k)	1.40 Å	6R55	6R55	6R55	6R55	6R55	6R55
crystal structure of ppep-1(k101e/e184k)	1.77 Å	6R56	6R56	6R56	6R56	6R56	6R56
crystal structure of ppep-1(Glu143Ala/Tyr178Phe/Glu184Ala) in complex with substrate peptide ac-evnppvp-conh2	1.90 Å	6R57	6R57	6R57	6R57	6R57	6R57
crystal structure of ppep-1(Glu143Ala/Tyr178Phe/Glu184Ala) in complex with substrate peptide ac-evnapvp-conh2	1.90 Å	6R58	6R58	6R58	6R58	6R58	6R58
crystal structure of ppep-1(Glu143Ala/Tyr178Phe) in complex with substrate peptide ac-evappvp-nh2	1.65 Å	6R59	6R59	6R59	6R59	6R59	6R59
crystal structure of ppep-1(w103f)	1.48 Å	6R5A	6R5A	6R5A	6R5A	6R5A	6R5A
crystal structure of ppep-1(Trp103His/Glu143Ala/Tyr178Phe) in complex with substrate peptide ac-evnppvp-conh2	2.06 Å	6R5B	6R5B	6R5B	6R5B	6R5B	6R5B
crystal structure of ppep-1(Trp103His/Glu143Ala/Tyr178Phe) in complex with substrate peptide ac-evnppvp-conh2	1.88 Å	6R5C	6R5C	6R5C	6R5C	6R5C	6R5C