Structure for peptidase S01.229: mannan-binding lectin-associated serine peptidase 2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

PDB Organism Resolution Comment
1Q3X Homo sapiens 2.23 Å catalytic domain only
Catalytic residues are shown in ball-and-stick representation: His483 in purple, Asp532 in pink and Ser633 in orange. The structural sodium atom is shown as a brown CPK sphere. The fragment of the heavy chain (CCP2-SP) is shown in grey ribbon representation.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Homo sapiens
catalytic domain only 2.23 Å 1Q3X 1Q3X 1Q3X 1Q3X 1Q3X 1Q3X Harmat et al., 2004
zymogen catalytic region 2.18 Å 1ZJK 1ZJK 1ZJK 1ZJK 1ZJK 1ZJK Gal et al., 2005
complex with complement c4 3.75 Å 4FXG 4FXG 4FXG 4FXG 4FXG 4FXG
complex with human complement c4 3.75 Å 5JPM 5JPM 5JPM 5JPM 5JPM 5JPM
Rattus norvegicus
mature  peptidase 2.70 Å 1NT0 1NT0 1NT0 1NT0 1NT0 1NT0 Feinberg et al., 2003