Structure for peptidase S08.070: kexin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

PDB Organism Resolution Comment
1OT5_A Saccharomyces cerevisiae 2.40 Å complex with N-acetyl-L-alanyl-6-ammonio-N-[(1R)-4-carbamimidamido-1-(dihydroxyboranyl)butyl]-L-norleucinamide
Catalytic residues are shown in ball-and-stick representation: Asp175 in pink, His213 in purple and Ser385 in orange. The structural calcium ions are shown as yellow CPK spheres. Carbohydrates are shown as CPK spheres in yellow.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Saccharomyces cerevisiae
complex with N-acetyl-L-alanyl-6-ammonio-N-[(1R)-4-carbamimidamido-1-(dihydroxyboranyl)butyl]-L-norleucinamide 2.40 Å 1OT5 1OT5 1OT5 1OT5 1OT5 1OT5 Holyoak et al., 2003
complex with Ac-Arg-Glu-Lys-boroArg peptidyl boronic acid inhibitor 2.20 Å 1R64 1R64 1R64 1R64 1R64 1R64 Holyoak et al., 2004
complex with N~2~-acetyl-N~5~-[amino(iminio)methyl]-L-ornithyl-L-alpha-glutamyl-N-[(1S)-5-amino-1-(chloroacetyl)pentyl]-N~5~-[amino(iminio)methyl]-L-ornithinamide 1.90 Å 2ID4 2ID4 2ID4 2ID4 2ID4 2ID4 Wheatley & Holyoak, 2007