Structure for peptidase homologue T01.983: proteasome subunit beta 3
 
TERTIARY STRUCTURE DATA | ||||||||
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Comment | Resolution | PDB | PDBe | SCOP | CATH | PDBSum | Proteopedia | Reference |
Homo sapiens | ||||||||
20S proteasome | 2.60 Å | 4R3O | 4R3O | 4R3O | 4R3O | 4R3O | 4R3O | Harshbarger et al., 2015 |
20S proteasome; complex with carfilzomib | 2.89 Å | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | 4R67 | Harshbarger et al., 2015 |
cryo-em reveals the conformation of a substrate analogue in the human 20s proteasome core | 3.50 Å | 5A0Q | 5A0Q | 5A0Q | 5A0Q | 5A0Q | 5A0Q | |
26S proteasome; complex with USP14-UbAl | 4.35 Å | 5GJQ | 5GJQ | 5GJQ | 5GJQ | 5GJQ | 5GJQ | |
26S proteasome | 3.50 Å | 5GJR | 5GJR | 5GJR | 5GJR | 5GJR | 5GJR | |
native human 20s proteasome at 1.8 angstrom ***caveat 5le5 6v1 u 47 has wrong chirality at atom c1 | 1.80 Å | 5LE5 | 5LE5 | 5LE5 | 5LE5 | 5LE5 | 5LE5 | |
native human 20s proteasome in mg-acetate at 2.2 angstrom ***caveat 5lex 6v1 u 47 has wrong chirality at atom c1 | 2.20 Å | 5LEX | 5LEX | 5LEX | 5LEX | 5LEX | 5LEX | |
20s proteasome; complex with oprozomib | 1.90 Å | 5LEY | 5LEY | 5LEY | 5LEY | 5LEY | 5LEY | |
20s proteasome; complex with oprozomib in mg-acetate | 2.19 Å | 5LEZ | 5LEZ | 5LEZ | 5LEZ | 5LEZ | 5LEZ | |
human 20s proteasome complex with epoxomicin at 2.4 angstrom ***caveat 5lf0 6v1 u 47 has wrong chirality at atom c1 iml c 2 has wrong ***caveat 2 5lf0 chirality at atom cb iml d 2 has wrong chirality at atom ca ***caveat 3 5lf0 iml d 2 has wrong chirality | 2.41 Å | 5LF0 | 5LF0 | 5LF0 | 5LF0 | 5LF0 | 5LF0 | |
human 20s proteasome complex with dihydroeponemycin at 2.0 angstrom ***caveat 5lf1 6v1 u 47 has wrong chirality at atom c1 | 2.00 Å | 5LF1 | 5LF1 | 5LF1 | 5LF1 | 5LF1 | 5LF1 | |
human 20s proteasome complex with bortezomib at 2.1 angstrom ***caveat 5lf3 6v1 u 47 has wrong chirality at atom c1 | 2.10 Å | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | 5LF3 | |
human 20s proteasome complex with delanzomib at 2.0 angstrom ***caveat 5lf4 6v1 u 47 has wrong chirality at atom c1 6v7 n 307 has wrong ***caveat 2 5lf4 chirality at atom c9 6v7 y 306 has wrong chirality at atom ***caveat 3 5lf4 c9 | 1.99 Å | 5LF4 | 5LF4 | 5LF4 | 5LF4 | 5LF4 | 5LF4 | |
human 20s proteasome complex with z-lly-ketoaldehyde at 2.1 angstrom ***caveat 5lf6 6v1 u 47 has wrong chirality at atom c1 | 2.07 Å | 5LF6 | 5LF6 | 5LF6 | 5LF6 | 5LF6 | 5LF6 | |
human 20s proteasome complex with ixazomib at 2.0 angstrom ***caveat 5lf7 6v1 u 47 has wrong chirality at atom c1 | 2.00 Å | 5LF7 | 5LF7 | 5LF7 | 5LF7 | 5LF7 | 5LF7 | |
the human 26s proteasome at 6.8 ang. ***caveat 5ln3 pro h 311 has wrong chirality at atom ca thr n 752 has wrong ***caveat 2 5ln3 chirality at atom ca | 6.80 Å | 5LN3 | 5LN3 | 5LN3 | 5LN3 | 5LN3 | 5LN3 | |
26s proteasome; complex with oprozomib | 3.80 Å | 5M32 | 5M32 | 5M32 | 5M32 | 5M32 | 5M32 | |
structural basis for dynamic regulation of the human 26s proteasome ***caveat 5t0g entry contains improper peptide linkages. | 4.40 Å | 5T0G | 5T0G | 5T0G | 5T0G | 5T0G | 5T0G | |
structural basis for dynamic regulation of the human 26s proteasome ***caveat 5t0h entry contains improper peptide linkages. | 6.80 Å | 5T0H | 5T0H | 5T0H | 5T0H | 5T0H | 5T0H | |
structural basis for dynamic regulation of the human 26s proteasome ***caveat 5t0i entry contains improper peptide linkages. residue arg k 20 ***caveat 2 5t0i is incorrectly modeled. | 8.00 Å | 5T0I | 5T0I | 5T0I | 5T0I | 5T0I | 5T0I | |
structural basis for dynamic regulation of the human 26s proteasome ***caveat 5t0j entry contains improper peptide linkages. | 8.00 Å | 5T0J | 5T0J | 5T0J | 5T0J | 5T0J | 5T0J | |
nucleotide-driven triple-state remodeling of the aaa-atpase channel inthe activated human 26s proteasome | 3.50 Å | 5VFO | 5VFO | 5VFO | 5VFO | 5VFO | 5VFO | |
nucleotide-driven triple-state remodeling of the aaa-atpase channel inthe activated human 26s proteasome | 4.90 Å | 5VFR | 5VFR | 5VFR | 5VFR | 5VFR | 5VFR | |
nucleotide-driven triple-state remodeling of the aaa-atpase channel inthe activated human 26s proteasome | 7.00 Å | 5VFT | 5VFT | 5VFT | 5VFT | 5VFT | 5VFT | |
cryo-em structure of human immunoproteasome with a novel noncompetitive inhibitor that selectively inhibits activated lymphocytes | 3.80 Å | 6AVO | 6AVO | 6AVO | 6AVO | 6AVO | 6AVO | |
endogeneous native human 20s proteasome | 3.50 Å | 6R70 | 6R70 | 6R70 | 6R70 | 6R70 | 6R70 | |
Mus musculus | ||||||||
20S proteasome; complex with PR-957 | 2.90 Å | 3UNB | 3UNB | 3UNB | 3UNB | 3UNB | 3UNB | Huber et al., 2012 |
20S proteasome | 3.20 Å | 3UNE | 3UNE | 3UNE | 3UNE | 3UNE | 3UNE | Huber et al., 2012 |
20S immunoproteasome; complex with PR-957 | 2.90 Å | 3UNF | 3UNF | 3UNF | 3UNF | 3UNF | 3UNF | Huber et al., 2012 |
20S immunoproteasome | 3.20 Å | 3UNH | 3UNH | 3UNH | 3UNH | 3UNH | 3UNH | Huber et al., 2012 |
Rattus norvegicus | ||||||||
ground state 26s proteasome (gs2) | 12.30 Å | 6EPC | 6EPC | 6EPC | 6EPC | 6EPC | 6EPC | |
substrate processing state 26s proteasome (sps1) ***caveat 6epd pro 2 231 has wrong chirality at atom ca | 15.40 Å | 6EPD | 6EPD | 6EPD | 6EPD | 6EPD | 6EPD | |
substrate processing state 26s proteasome (sps2) | 12.80 Å | 6EPE | 6EPE | 6EPE | 6EPE | 6EPE | 6EPE | |
ground state 26s proteasome (gs1) | 11.80 Å | 6EPF | 6EPF | 6EPF | 6EPF | 6EPF | 6EPF |