The Electron Microscopy Data Bank (EMDB) is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, helical reconstruction, electron tomography, subtomogram averaging, and electron crystallography. More...
As of 15 May 2024, EMDB contains 35462 entries (latest entries, trends).
EMDB News
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06 January 2024: We are delighted to share that EMDB has officially been elevated to a Core Data Resource by ELIXIR, recognising it as a European data resource of fundamental importance to the wider life-science community and the long-term preservation of biological data.
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22 November 2023: We are happy to share the most recent version of the EMDB Nucleic Acids Research paper. The paper describes recent developments and future plans of the EMDB in the context of the worldwide Protein Data Bank. Check it out now! https://doi.org/10.1093/nar/gkad1019
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(Show all)Cryo-EM structure of tetrameric human SAMHD1 State V - Depleted relaxed
Human histone H2B variant H2BFWT Cryo-EM structure with 601 DNA sequence
HIV-1 capsid-SP1 subtomogram averaging obtained from EMPIAR-10164 using TomoNet and Relion4 (4 tilt-series)
SARS-CoV-2 Omicron BA.4 spike trimer (6P) in complex with 3 D1F6 Fabs (2 RBD up)
The Anoxybacillus pushchinoensis ORF-less Group IIC Intron HYER1 at symmetric post cleavge state
nhTMEM16 R432A mutant in lipid nanodiscs with MSP1E3 scaffold protein in the presence of Ca2+
SARS-CoV-2 Omicron BA.4 spike trimer (6P) in complex with 3 D1F6 Fabs (1 RBD up)
Thinner is not always better: Optimising cryo lamellae for subtomogram averaging - Ion-damage layer analysis
Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, ADP-ribose, Adenosine monophosphate, and Ribose-5-phosphate, closed state
Cryo-EM Structure of Spike Glycoprotein from Civet Coronavirus SZ3 in Closed Conformation
Cryo-EM structure of the human TRPM4 in complex with calcium at 18 degrees Celsius
The Streptococcus azizii ORF-less Group IIC intron HYER2 at apo state
HIV Env BG505_MD39_B16 SOSIP boosting trimer in complex with B16_d77.5 mouse Fab and RM20A3 Fab
Cryo-EM structure of the Rpd3S-nucleosome complex from budding yeast in State 3
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN
Cryo-EM structure of the human TRPM4 channel in complex with calcium and ATP at 37 degrees Celsius
Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant desipramine in an inward-open state at resolution of 2.5 angstrom.
Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, open state
HIV Env BG505_MD39_B11 SOSIP boosting trimer in complex with B11_d77.7 mouse Fab and RM20A3 Fab
The Anoxybacillus pushchinoensis ORF-less Group IIC Intron DR1 at symmetric pre-cleavage state
Structure of the non-canonical CTLH E3 substrate receptor WDR26 bound to YPEL5
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and decavanadate at 37 degrees Celsius
Cryo-EM structure of the human TRPM4 channel in complex with calcium and decavanadate at 37 degrees Celsius
Cryo-EM structure of the human TRPM4 in complex with calcium at 37 degrees Celsius
Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate
SARS-CoV-2 Omicron BA.4 spike trimer (6P) in complex with D1F6 Fab, focused refinement of RBD region
Buspirone-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex
A homotrimeric GPCR architecture of the human cytomegalovirus (UL78) revealed by cryo-EM
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium and ATP at 37 degrees Celsius
SARS-CoV-2 Omicron BA.1 spike trimer (x2-4P) in complex with 3 D1F6 Fabs (0 RBD up)
NMNAT1 loop-bound RANBP9-TWA1-WDR26 module of WDR26-CTLH E3 ligase
HIV Envelope trimer CH505 SOSIP.664 in complex with wild type CH103 antibody
Structure of the NCOA4 (Nuclear Receptor Coactivator 4)-FTH1 (H-Ferritin) complex
NMNAT1 core-bound RANBP9-TWA1-WDR26 module of WDR26-CTLH E3 ligase
Cryo-EM structure of tetrameric human SAMHD1 State II - Hemi-relaxed
Human serotonin 5-HT3A receptor in complex with vortioxetine (nanodiscs, ECD, active/distorted conformation)
Cryo-EM structure of human norepinephrine transporter NET in an inward-open state at resolution of 2.5 angstrom
Human serotonin 5-HT3A receptor (apo, active/distorted conformation)
SARS-CoV-2 Omicron BA.2 spike trimer (6P) in complex with 3 D1F6 Fabs (2 RBD up)
5-MeO-DMT-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex
HIV Envelope trimer BG505 SOSIP.664 in complex with wild type CH103 antibody
Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, closed state
CryoEM structure of H7 hemagglutinin from A/Shanghai2/2013 H7N9 in complex with a human neutralizing antibody H7.HK1
Cryo-EM structure of human norepinephrine transporter NET in the presence of dopamine in an inward-open state at resolution of 3.0 angstrom.
Structure of the non-canonical CTLH E3 substrate receptor WDR26 bound to NMNAT1 substrate
Cryo-EM structure of the Rpd3S-nucleosome complex from budding yeast in State 1
Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of EDTA, apo state
Cryo-EM structure of an Enterobacter GH43 Beta-Xylosidase: EcXyl43
Cryo-EM structure of tetrameric human SAMHD1 State IV - Depleted relaxed
Cryo-EM structure of the human TRPM4 channel subunit in complex with calcium 37 degrees Celsius
The Anoxybacillus pushchinoensis ORF-less Group IIC Intron HYER1 at symmetric apo state
Thinner is not always better: Optimising cryo lamellae for subtomogram averaging
HIV Env germline targeting BG505_MD64_N332-GT5 SOSIP in complex with V3-glycan polyclonal Fab isolated from immunized wild type mice, and NHP monoclonal Fab RM20A3
Thinner is not always better: Optimising cryo lamellae for subtomogram averaging - Lamella thickness analysis
Vilazodone-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex
Cryo-ET map of RuBisCO-SSUL at 5.9 angstroms from Synechococcus elongatus PCC 7942 beta-carboxysome
Cryo-EM structure of DRH-1 helicase and C-terminal domain bound to dsRNA
Cryo-EM structure of the Rpd3S-nucleosome complex from budding yeast in State 2
Cryo-EM structure of human norepinephrine transporter NET in the presence of the antidepressant bupropion in an inward-open state at resolution of 3.0 angstrom.
Cryo-EM structure of TRPM2 chanzyme (without NUDT9-H domain) in the presence of Ca and ADP-ribose
Cryo-EM structure of C. elegans antiviral complex Dicer-1, DRH-1, and RDE-4 bound to one dsRNA
Human serotonin 5-HT3A receptor in complex with vortioxetine (detergent, ECD only, active/distorted conformation)
PhiCb5 maturation protein with Caulobacter crescentus bNY30a pili
Cryo-ET map of RuBisCO at the outermost layer that is loosely attached to the shell of Synechococcus elongatus PCC 7942 beta-carboxysome
Cryo-ET structure of RuBisCO from 3.9 angstroms Synechococcus elongatus PCC 7942
Local map of SV2A LD4-BoNT/A2 Hc from SV2A-BoNT/A2 Hc-brivaracetam complex
CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : LM32Cs3H1 sKO STRAIN
SARS-CoV-2 Omicron BA.2 spike trimer (6P) in complex with 3 D1F6 Fabs (1 RBD up)
Structure of the FADD/Caspase-8/cFLIP death effector domain assembly
CryoEM structure of H7 hemagglutinin from A/Shanghai2/2013 H7N9 in complex with a human neutralizing antibody H7.HK2
SARS-CoV-2 Omicron BA.2 spike trimer (6P) in complex with D1F6 Fab, focused refinement of RBD region
Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '2 up 1 down' RBD conformation
Cryo-ET map of RuBisCO at the outermost layer that is tightly attached to the shell of Synechococcus elongatus PCC 7942 beta-carboxysome
Structure of p53 DNA-binding domain and ZNF568 KRAB domain complex
HIV Envelope BG505 SOSIP.664 in complex with one Fab of CH103 E75K/D76N mutant
Cryo-EM structure of TRPM2 chanzyme (E1114A) in the presence of Magnesium and ADP-ribose, closed state
Cryo-EM structure of human norepinephrine transporter NET in the presence of norepinephrine in an inward-open state at resolution of 2.9 angstrom.
HIV Env germline targeting BG505_MD64_N332-GT5 SOSIP in complex with V3-glycan polyclonal Fab isolated from immunized BG18HCgl knock-in mice
Cryo-EM structure of the human TRPM4 channel in the presence of EDTA at 37 degrees Celsius
Cryo-EM structure of the AlbAB cyclodipeptide oxidase enzyme filament
Structure of the FADD/Caspase-8/cFLIP death effector domain assembly
Cryo-EM structure of C. elegans antiviral complex Dicer-1, DRH-1, and RDE-4 bound to two dsRNA
4-F, 5-MeO-PyrT-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex
Cryo-EM structure of TRPM2 chanzyme in the presence of Magnesium and ADP-ribose, open state
Cryo-ET map of RuBisCO at 4.4 angstroms from Synechococcus elongatus PCC 7942 beta-carboxysome