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Crystal structure of a truncated variant of indole-3-glycerol phosphate synthase from Sulfolobus solfataricus

X-ray diffraction
2.8Å resolution
PDB entry 2c3z coloured by chain, front view.
PDB entry 2c3z coloured by chain, side view.
PDB entry 2c3z coloured by chain, top view.
Source organism: Saccharolobus solfataricus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Indole-3-glycerol phosphate synthase
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Multimeric state: monomeric
Accessible surface area: 9701.71 Å2
Buried surface area: 254.35 Å2
Dissociation area: 127.18 Å2
Dissociation energy (ΔGdiss): 20.34 kcal/mol
Dissociation entropy (TΔSdiss): 0.63 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-170286

Macromolecules

Indole-3-glycerol phosphate synthase
Chain: A
Length: 222 amino acids
Theoretical weight: 25.48 KDa
Source organism: Saccharolobus solfataricus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q06121 (Residues: 27-248; Coverage: 90%)
Gene names: SSO0895, trpC
Pfam: Indole-3-glycerol phosphate synthase
InterPro:
CATH: Aldolase class I
Indole-3-glycerol phosphate synthase in PDB entry 2c3z, assembly 1, front view.
Indole-3-glycerol phosphate synthase in PDB entry 2c3z, assembly 1, side view.
Indole-3-glycerol phosphate synthase in PDB entry 2c3z, assembly 1, top view.
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