Protein Data Bank in Europe

Chain: A
Length: 1743 amino acids
Theoretical weight: 194.11 KDa
Source organism: Linanthus concinnus
UniProt:

• Canonical: C4R4Y0 (Residues: 1-1743; Coverage: 100%)

Gene name: PAS_chr3_0568
Pfam:

• RNA polymerase Rpb1, domain 1
• RNA polymerase Rpb1, domain 2
• RNA polymerase Rpb1, domain 3
• RNA polymerase Rpb1, domain 4
• RNA polymerase Rpb1, domain 5
• RNA polymerase Rpb1, domain 6
• RNA polymerase Rpb1, domain 7
• RNA polymerase Rpb1 C-terminal repeat

InterPro:

• RNA polymerase Rpb1, clamp domain superfamily
• RNA polymerase Rpb1, domain 1
• DNA-directed RNA polymerase, subunit beta-prime
• RNA polymerase, N-terminal
• RNA polymerase, alpha subunit
• RNA polymerase Rpb1, domain 3
• RNA polymerase Rpb1, domain 3 superfamily
• RNA polymerase Rpb1, funnel domain superfamily
• RNA polymerase Rpb1, domain 4
• RNA polymerase Rpb1, domain 5
• RNA polymerase Rpb1, domain 6
• RNA polymerase Rpb1, domain 7
• RNA polymerase Rpb1, domain 7 superfamily
• RNA polymerase II, heptapeptide repeat, eukaryotic

Chain: B
Length: 1227 amino acids
Theoretical weight: 139.75 KDa
Source organism: Komagataella phaffii GS115
UniProt:

• Canonical: C4QZQ7 (Residues: 1-1227; Coverage: 100%)

Gene name: PAS_chr2-1_0125
Pfam:

• RNA polymerase beta subunit
• RNA polymerase Rpb2, domain 2
• RNA polymerase Rpb2, domain 3
• RNA polymerase Rpb2, domain 4
• RNA polymerase Rpb2, domain 5
• RNA polymerase Rpb2, domain 6
• RNA polymerase Rpb2, domain 7

InterPro:

• DNA-directed RNA polymerase, subunit 2
• RNA polymerase, beta subunit, protrusion
• RNA polymerase Rpb2, domain 2
• RNA polymerase Rpb2, domain 2 superfamily
• RNA polymerase Rpb2, domain 3
• RNA polymerase Rpb2, domain 4
• RNA polymerase Rpb2, domain 5
• DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
• DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily
• RNA polymerase Rpb2, OB-fold
• RNA polymerase, beta subunit, conserved site
• RNA polymerase Rpb2, domain 7

Chain: C
Length: 304 amino acids
Theoretical weight: 34.22 KDa
Source organism: Komagataella phaffii GS115
UniProt:

• Canonical: C4R7L2 (Residues: 1-304; Coverage: 100%)

Gene name: PAS_chr4_0344
Pfam:

• RNA polymerase Rpb3/Rpb11 dimerisation domain
• RNA polymerase Rpb3/RpoA insert domain

InterPro:

• RNA polymerase, RBP11-like subunit
• DNA-directed RNA polymerase subunit Rpo3/Rpb3/RPAC1
• DNA-directed RNA polymerase, RpoA/D/Rpb3-type
• DNA-directed RNA polymerase, 30-40kDa subunit, conserved site
• DNA-directed RNA polymerase, insert domain superfamily
• DNA-directed RNA polymerase, insert domain

CATH:

• RNA polymerase, RBP11-like subunit
• DNA-directed RNA polymerase, insert domain

Chain: D
Length: 186 amino acids
Theoretical weight: 20.62 KDa
Source organism: Komagataella phaffii GS115
UniProt:

• Canonical: C4R2U9 (Residues: 1-186; Coverage: 100%)

Gene name: PAS_chr2-2_0104
Pfam: RNA polymerase Rpb4
InterPro:

• DNA-directed RNA polymerase II subunit Rpb4-like
• RNA polymerase Rpb4/RPC9, core
• HRDC-like superfamily
• RNA polymerase subunit Rpb4/RPC9
• Rpb4/RPC9 superfamily

CATH: Growth Hormone; Chain: A;

Chain: E
Length: 214 amino acids
Theoretical weight: 24.96 KDa
Source organism: Komagataella phaffii GS115
UniProt:

• Canonical: C4R3P8 (Residues: 1-214; Coverage: 100%)

Gene name: PAS_chr3_0157
Pfam:

• RNA polymerase Rpb5, N-terminal domain
• RNA polymerase Rpb5, C-terminal domain

InterPro:

• DNA-directed RNA polymerase subunit Rpo5/Rpb5
• RNA polymerase Rpb5, N-terminal domain superfamily
• RNA polymerase, Rpb5, N-terminal
• RPB5-like RNA polymerase subunit superfamily
• RNA polymerase, subunit H/Rpb5 C-terminal
• RNA polymerase, subunit H/Rpb5, conserved site

CATH:

• RNA polymerase, Rpb5, N-terminal domain
• RPB5-like RNA polymerase subunit

Chain: F
Length: 155 amino acids
Theoretical weight: 17.8 KDa
Source organism: Komagataella phaffii GS115
UniProt:

• Canonical: C4R1V1 (Residues: 1-155; Coverage: 100%)

Gene name: PAS_chr2-2_0434
Pfam: RNA polymerase Rpb6
InterPro:

• Archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit
• DNA-directed RNA polymerase, subunit RPB6
• RPB6/omega subunit-like superfamily
• RNA polymerase, subunit omega/Rpo6/RPB6
• DNA-directed RNA polymerase, 14-18kDa subunit, conserved site

CATH: Eukaryotic RPB6 RNA polymerase subunit

Chain: G
Length: 171 amino acids
Theoretical weight: 18.8 KDa
Source organism: Komagataella phaffii GS115
UniProt:

• Canonical: C4R9A1 (Residues: 1-171; Coverage: 100%)

Gene name: PAS_chr4_0906
Pfam:

• SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397
• S1 RNA binding domain

InterPro:

• RNA polymerase Rpb7-like, N-terminal domain superfamily
• RNA polymerase subunit Rpb7-like
• RNA polymerase Rpb7-like , N-terminal
• S1 domain
• Nucleic acid-binding, OB-fold

CATH:

• RNA polymerase Rpb7-like, N-terminal domain
• Nucleic acid-binding proteins

Chain: H
Length: 145 amino acids
Theoretical weight: 16.25 KDa
Source organism: Komagataella phaffii GS115
UniProt:

• Canonical: C4R273 (Residues: 1-145; Coverage: 100%)

Gene name: PAS_chr2-2_0309
Pfam: RNA polymerase Rpb8
InterPro:

• Nucleic acid-binding, OB-fold
• DNA-directed RNA polymerases I, II, and III subunit RPABC3

CATH: Nucleic acid-binding proteins

Chain: I
Length: 115 amino acids
Theoretical weight: 13.61 KDa
Source organism: Komagataella phaffii CBS 7435
UniProt:

• Canonical: F2QPE6 (Residues: 1-115; Coverage: 100%)

Gene names: PP7435_Chr1-1144, RPB9
Pfam:

• RNA polymerases M/15 Kd subunit
• Transcription factor S-II (TFIIS)

InterPro:

• DNA-directed RNA polymerase subunit/transcription factor S
• DNA-directed RNA polymerase II subunit RPB9-like, zinc ribbon
• DNA-directed RNA polymerase M, 15kDa subunit, conserved site
• Pol II subunit B9, C-terminal zinc ribbon
• Zinc finger, TFIIS-type

Chain: J
Length: 72 amino acids
Theoretical weight: 8.55 KDa
Source organism: Komagataella phaffii GS115
UniProt:

• Canonical: C4R009 (Residues: 1-72; Coverage: 100%)

Gene name: PAS_chr2-1_0223
Pfam: RNA polymerases N / 8 kDa subunit
InterPro:

• DNA-directed RNA polymerase subunit RPABC5/Rpb10
• RNA polymerase subunit RPB10
• RNA polymerases, subunit N, zinc binding site

CATH: Homeodomain-like

Chain: K
Length: 118 amino acids
Theoretical weight: 13.83 KDa
Source organism: Komagataella phaffii GS115
UniProt:

• Canonical: C4R3Z5 (Residues: 1-118; Coverage: 100%)

Gene name: PAS_chr3_0244
Pfam: RNA polymerase Rpb3/Rpb11 dimerisation domain
InterPro:

• RNA polymerase, RBP11-like subunit
• RNA polymerase RBP11
• DNA-directed RNA polymerase subunit Rpo11-like
• DNA-directed RNA polymerase, RBP11-like dimerisation domain
• DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site

CATH: RNA polymerase, RBP11-like subunit

Chain: L
Length: 72 amino acids
Theoretical weight: 7.86 KDa
Source organism: Komagataella phaffii CBS 7435
UniProt:

• Canonical: F2QMI1 (Residues: 1-72; Coverage: 100%)

Gene names: PP7435_Chr1-0476, RPC10
Pfam: DNA directed RNA polymerase, 7 kDa subunit
InterPro:

• DNA-directed RNA polymerases I, II, and III subunit RPABC4
• RNA polymerase subunit RPABC4/transcription elongation factor Spt4
• RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4

CATH: RNA polymerase ii, chain L

Chain: M
Length: 113 amino acids
Theoretical weight: 12.61 KDa
Source organism: Komagataella phaffii GS115
Expression system: Escherichia coli
UniProt:

• Canonical: C4QZ45 (Residues: 1-110; Coverage: 100%)

Gene name: PAS_c121_0006
Pfam: Transcription elongation factor Elf1 like
InterPro:

• Transcription elongation factor 1
• Transcription elongation factor 1 superfamily

CATH: N-terminal domain of TfIIb

Chain: V
Length: 108 amino acids
Theoretical weight: 12.04 KDa
Source organism: Komagataella phaffii GS115
Expression system: Escherichia coli
UniProt:

• Canonical: C4R0E6 (Residues: 8-114; Coverage: 94%)

Gene name: PAS_chr2-1_0350
Pfam: Spt4/RpoE2 zinc finger
InterPro:

• RNA polymerase subunit RPABC4/transcription elongation factor Spt4
• Transcription initiation Spt4
• Spt4 superfamily
• Spt4/RpoE2 zinc finger

CATH: Herpes Virus-1

Chain: W
Length: 911 amino acids
Theoretical weight: 101.46 KDa
Source organism: Komagataella phaffii GS115
Expression system: Escherichia coli
UniProt:

• Canonical: C4R370 (Residues: 1-908; Coverage: 100%)

Gene name: PAS_chr3_1136
Pfam:

• Spt5 transcription elongation factor, acidic N-terminal
• Early transcription elongation factor of RNA pol II, NGN section
• KOW motif
• Spt5 C-terminal nonapeptide repeat binding Spt4

InterPro:

• Transcription elongation factor Spt5, eukaryote
• Transcription elongation factor SPT5
• Spt5 transcription elongation factor, N-terminal
• NusG, N-terminal domain superfamily
• NGN domain
• NGN domain, eukaryotic
• KOW
• Spt5, KOW domain repeat 1
• Large ribosomal subunit protein uL2, domain 2
• Spt5, KOW domain repeat 2
• Translation protein SH3-like domain superfamily
• Spt5, KOW domain repeat 3
• Spt5, KOW domain repeat 4
• Spt5, KOW domain repeat 5

Chains: a, e
Length: 139 amino acids
Theoretical weight: 15.64 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

• Canonical: P84243 (Residues: 1-136; Coverage: 100%)

Gene names: H3-3A, H3-3B, H3.3A, H3.3B, H3F3, H3F3A, H3F3B, PP781
Pfam: Core histone H2A/H2B/H3/H4
InterPro:

• Histone H3/CENP-A
• Histone H2A/H2B/H3
• Histone-fold

CATH: Histone, subunit A

Chains: b, f
Length: 106 amino acids
Theoretical weight: 11.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

• Canonical: P62805 (Residues: 1-103; Coverage: 100%)

Gene names: H4-16, H4/A, H4/B, H4/C, H4/D, H4/E, H4/G, H4/H, H4/I, H4/J, H4/K, H4/M, H4/N, H4/O, H4C1, H4C11, H4C12, H4C13, H4C14, H4C15, H4C16, H4C2, H4C3, H4C4, H4C5, H4C6, H4C8, H4C9, H4F2, H4FA, H4FB, H4FC, H4FD, H4FE, H4FG, H4FH, H4FI, H4FJ, H4FK, H4FM, H4FN, H4FO, HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4, HIST2H4A, HIST2H4B, HIST4H4
Pfam: Centromere kinetochore component CENP-T histone fold
InterPro:

• Histone-fold
• Histone H4
• Histone H4, conserved site
• TATA box binding protein associated factor (TAF), histone-like fold domain
• CENP-T/Histone H4, histone fold

CATH: Histone, subunit A

Chains: c, g
Length: 133 amino acids
Theoretical weight: 14.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

• Canonical: P04908 (Residues: 1-130; Coverage: 100%)

Gene names: H2AC4, H2AC8, H2AFA, H2AFM, HIST1H2AB, HIST1H2AE
Pfam:

• Core histone H2A/H2B/H3/H4
• C-terminus of histone H2A

InterPro:

• Histone H2A/H2B/H3
• Histone-fold
• Histone H2A
• Histone H2A conserved site
• Histone H2A, C-terminal domain

CATH: Histone, subunit A

Chains: d, h
Length: 129 amino acids
Theoretical weight: 14.22 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

• Canonical: P06899 (Residues: 1-126; Coverage: 100%)

Gene names: H2BC11, H2BFR, HIST1H2BJ
Pfam: Core histone H2A/H2B/H3/H4
InterPro:

• Histone H2A/H2B/H3
• Histone-fold
• Histone H2B

CATH: Histone, subunit A