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Drosophila melanogaster TRAPPIII partial complex: core plus C8 and C11 attached region

Electron Microscopy
5.8Å resolution
PDB entry 7b6r coloured by chain, front view.
PDB entry 7b6r coloured by chain, side view.
PDB entry 7b6r coloured by chain, top view.
Source organism: Drosophila melanogaster
Assembly composition:
hetero decamer (preferred)
Entry contents: 9 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero decamer
Accessible surface area: 102059.25 Å2
Buried surface area: 21940.76 Å2
Dissociation area: 1,165.64 Å2
Dissociation energy (ΔGdiss): -11.67 kcal/mol
Dissociation entropy (TΔSdiss): 30.28 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-106775

Macromolecules

FI18195p1
Chain: A
Length: 307 amino acids
Theoretical weight: 35.41 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q9VW22 (Residues: 355-661; Coverage: 23%)
Gene names: CG8793, Dmel\CG8793, Dmel_CG8793, TRAPPC8, l(3)76BDm, l(3)76BDm-RA, l(3)L3809
Pfam: ER-Golgi trafficking TRAPP I complex 85 kDa subunit
InterPro: TRAPP III complex, Trs85
FI18195p1 in PDB entry 7b6r, assembly 1, front view.
FI18195p1 in PDB entry 7b6r, assembly 1, side view.
FI18195p1 in PDB entry 7b6r, assembly 1, top view.
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Trafficking protein particle complex subunit 11
Chain: B
Length: 718 amino acids
Theoretical weight: 81.85 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q8IRE3 (Residues: 1-718; Coverage: 54%)
Gene names: CG17569, Dmel\CG17569, Dmel_CG17569, TRAPPC11, gry, gryz, l(3)63Bd
Pfam: Foie gras liver health family 1
InterPro: Trafficking protein particle complex subunit 11
Trafficking protein particle complex subunit 11 in PDB entry 7b6r, assembly 1, front view.
Trafficking protein particle complex subunit 11 in PDB entry 7b6r, assembly 1, side view.
Trafficking protein particle complex subunit 11 in PDB entry 7b6r, assembly 1, top view.
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Trafficking protein particle complex subunit
Chains: C, I
Length: 178 amino acids
Theoretical weight: 20.49 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q9VSY8 (Residues: 1-178; Coverage: 100%)
Gene names: BET3, Bet3, Bet3p, CG3911, Dmel\CG3911, Dmel_CG3911, TRAPPC3, dBet3
Pfam: Transport protein particle (TRAPP) component
InterPro:
Trafficking protein particle complex subunit in PDB entry 7b6r, assembly 1, front view.
Trafficking protein particle complex subunit in PDB entry 7b6r, assembly 1, side view.
Trafficking protein particle complex subunit in PDB entry 7b6r, assembly 1, top view.
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GEO08327p1
Chain: D
Length: 152 amino acids
Theoretical weight: 17.6 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q9VF82 (Residues: 1-152; Coverage: 100%)
Gene names: BcDNA:RH37427, CG6196, Dmel\CG6196, Dmel_CG6196, TRAPPC6, Trs33, Trs33p, dTrs33
Pfam: Transport protein particle (TRAPP) component
InterPro:
TRAPP subunit 33 in PDB entry 7b6r, assembly 1, front view.
TRAPP subunit 33 in PDB entry 7b6r, assembly 1, side view.
TRAPP subunit 33 in PDB entry 7b6r, assembly 1, top view.
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Trafficking protein particle complex subunit
Chain: E
Length: 145 amino acids
Theoretical weight: 16.99 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q9VA95 (Residues: 1-145; Coverage: 100%)
Gene names: BET5, Bet5, Bet5p, CG1359, CG1359-RA, Dmel\CG1359, Dmel_CG1359, TRAPPC1
Pfam: Sybindin-like family
InterPro:
Trafficking protein particle complex subunit in PDB entry 7b6r, assembly 1, front view.
Trafficking protein particle complex subunit in PDB entry 7b6r, assembly 1, side view.
Trafficking protein particle complex subunit in PDB entry 7b6r, assembly 1, top view.
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Trafficking protein particle complex subunit
Chain: F
Length: 219 amino acids
Theoretical weight: 24.74 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q9VLI9 (Residues: 1-219; Coverage: 100%)
Gene names: CG9298, CG9298-RA, Dmel\CG9298, Dmel_CG9298, TRAPPC4, TRS23, Trs23, Trs23p
Pfam: Sybindin-like family
InterPro:
Trafficking protein particle complex subunit in PDB entry 7b6r, assembly 1, front view.
Trafficking protein particle complex subunit in PDB entry 7b6r, assembly 1, side view.
Trafficking protein particle complex subunit in PDB entry 7b6r, assembly 1, top view.
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Probable trafficking protein particle complex subunit 2
Chain: G
Length: 139 amino acids
Theoretical weight: 16.67 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q9VUZ1 (Residues: 1-139; Coverage: 100%)
Gene names: CG5161, Trs20, l(3)72Dh
Pfam: Sedlin, N-terminal conserved region
InterPro:
Probable trafficking protein particle complex subunit 2 in PDB entry 7b6r, assembly 1, front view.
Probable trafficking protein particle complex subunit 2 in PDB entry 7b6r, assembly 1, side view.
Probable trafficking protein particle complex subunit 2 in PDB entry 7b6r, assembly 1, top view.
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Trafficking protein particle complex subunit 5
Chain: H
Length: 194 amino acids
Theoretical weight: 22.37 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: Q7K2Q8 (Residues: 1-194; Coverage: 100%)
Gene names: CG10153, Dmel\CG10153, Dmel_CG10153, TRAPPC5, Trs31, Trs31p
Pfam: Transport protein particle (TRAPP) component
InterPro:
Trafficking protein particle complex subunit 5 in PDB entry 7b6r, assembly 1, front view.
Trafficking protein particle complex subunit 5 in PDB entry 7b6r, assembly 1, side view.
Trafficking protein particle complex subunit 5 in PDB entry 7b6r, assembly 1, top view.
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Trafficking protein particle complex subunit 2-like protein
Chain: J
Length: 138 amino acids
Theoretical weight: 15.51 KDa
Source organism: Drosophila melanogaster
Expression system: Spodoptera aff. frugiperda 1 BOLD-2017
UniProt:
  • Canonical: A1Z8I0 (Residues: 1-138; Coverage: 100%)
Gene names: CG9067, Dmel\CG9067, Dmel_CG9067, TRAPPC2L, Tca17
Pfam: Sedlin, N-terminal conserved region
InterPro:
Trafficking protein particle complex subunit 2-like protein in PDB entry 7b6r, assembly 1, front view.
Trafficking protein particle complex subunit 2-like protein in PDB entry 7b6r, assembly 1, side view.
Trafficking protein particle complex subunit 2-like protein in PDB entry 7b6r, assembly 1, top view.
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