Assemblies
Assembly Name:
THO complex
Multimeric state:
hetero pentamer
Accessible surface area:
126900.76 Å2
Buried surface area:
44555.06 Å2
Dissociation area:
2,613.36
Å2
Dissociation energy (ΔGdiss):
19.11
kcal/mol
Dissociation entropy (TΔSdiss):
15.49
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-126884
Macromolecules
Chain: F
Length: 752 amino acids
Theoretical weight: 87.94 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Spodoptera frugiperda
UniProt:
Pfam: THO complex subunit 1 transcription elongation factor
InterPro: THO complex, subunit THOC1
Length: 752 amino acids
Theoretical weight: 87.94 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P17629 (Residues: 1-752; Coverage: 100%)
Pfam: THO complex subunit 1 transcription elongation factor
InterPro: THO complex, subunit THOC1
Chain: G
Length: 1597 amino acids
Theoretical weight: 184.16 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Spodoptera frugiperda
UniProt:
Pfam:
Length: 1597 amino acids
Theoretical weight: 184.16 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P53552 (Residues: 1-1597; Coverage: 100%)
Pfam:
- THO complex subunit 2 N-terminus
- Transcription- and export-related complex subunit
- Transcription factor/nuclear export subunit protein 2
Chain: H
Length: 422 amino acids
Theoretical weight: 47.23 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Spodoptera frugiperda
UniProt:
Pfam: WD domain, G-beta repeat
InterPro:
Length: 422 amino acids
Theoretical weight: 47.23 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P53851 (Residues: 1-422; Coverage: 100%)
Pfam: WD domain, G-beta repeat
InterPro:
Chain: I
Length: 392 amino acids
Theoretical weight: 45.06 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Spodoptera frugiperda
UniProt:
Pfam: Tho complex subunit 7
InterPro: THO complex subunit 7/Mft1
Length: 392 amino acids
Theoretical weight: 45.06 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P33441 (Residues: 1-392; Coverage: 100%)
Pfam: Tho complex subunit 7
InterPro: THO complex subunit 7/Mft1
Chain: J
Length: 261 amino acids
Theoretical weight: 30.34 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Spodoptera frugiperda
UniProt:
Pfam: Tho complex subunit THP2
InterPro: THO complex subunit Thp2
Length: 261 amino acids
Theoretical weight: 30.34 KDa
Source organism: Saccharomyces cerevisiae S288C
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
O13539 (Residues: 1-261; Coverage: 100%)
Pfam: Tho complex subunit THP2
InterPro: THO complex subunit Thp2