Assemblies
Multimeric state:
hetero octadecamer
Accessible surface area:
117764.18 Å2
Buried surface area:
98467.05 Å2
Dissociation area:
1,150.17
Å2
Dissociation energy (ΔGdiss):
0.83
kcal/mol
Dissociation entropy (TΔSdiss):
12.22
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-236689
Macromolecules
Chain: A
Length: 431 amino acids
Theoretical weight: 47.27 KDa
Source organism: Sus scrofa
UniProt:
Pfam:
Length: 431 amino acids
Theoretical weight: 47.27 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
A0A4X1SZP7 (Residues: 28-458; Coverage: 93%)
Pfam:
- Respiratory-chain NADH dehydrogenase 51 Kd subunit
- SLBB domain
- NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
- NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily
- NADH ubiquinone oxidoreductase, F subunit
- NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain
- NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site
- NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily
- NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain
Chain: B
Length: 176 amino acids
Theoretical weight: 20.21 KDa
Source organism: Sus scrofa
UniProt:
Pfam: 4Fe-4S dicluster domain
InterPro:
Length: 176 amino acids
Theoretical weight: 20.21 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
A0A287BDC0 (Residues: 37-212; Coverage: 83%)
Pfam: 4Fe-4S dicluster domain
InterPro:
Chain: C
Length: 156 amino acids
Theoretical weight: 17.87 KDa
Source organism: Sus scrofa
UniProt:
Pfam: NADH ubiquinone oxidoreductase, 20 Kd subunit
InterPro:
Length: 156 amino acids
Theoretical weight: 17.87 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
A0A8D1TL60 (Residues: 41-196; Coverage: 80%)
Pfam: NADH ubiquinone oxidoreductase, 20 Kd subunit
InterPro:
Chain: E
Length: 115 amino acids
Theoretical weight: 13.81 KDa
Source organism: Sus scrofa
UniProt:
Pfam: Complex 1 protein (LYR family)
InterPro:
Length: 115 amino acids
Theoretical weight: 13.81 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
F1SJP6 (Residues: 40-154; Coverage: 75%)
Pfam: Complex 1 protein (LYR family)
InterPro:
Chain: F
Length: 86 amino acids
Theoretical weight: 9.84 KDa
Source organism: Sus scrofa
UniProt:
Pfam: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
InterPro:
Length: 86 amino acids
Theoretical weight: 9.84 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
F1RGE3 (Residues: 14-99; Coverage: 87%)
Pfam: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
InterPro:
Chain: G
Length: 88 amino acids
Theoretical weight: 10.13 KDa
Source organism: Sus scrofa
UniProt:
Pfam: Phosphopantetheine attachment site
InterPro:
Length: 88 amino acids
Theoretical weight: 10.13 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
A0A287AAR5 (Residues: 69-156; Coverage: 56%)
Pfam: Phosphopantetheine attachment site
InterPro:
Chain: H
Length: 112 amino acids
Theoretical weight: 12.95 KDa
Source organism: Sus scrofa
Length: 112 amino acids
Theoretical weight: 12.95 KDa
Source organism: Sus scrofa
Chain: I
Length: 112 amino acids
Theoretical weight: 12.52 KDa
Source organism: Sus scrofa
UniProt:
Pfam: NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Length: 112 amino acids
Theoretical weight: 12.52 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
A0A4X1VLA2 (Residues: 2-113; Coverage: 99%)
Pfam: NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Chain: J
Length: 341 amino acids
Theoretical weight: 38.84 KDa
Source organism: Sus scrofa
UniProt:
Pfam: NAD dependent epimerase/dehydratase family
InterPro:
Length: 341 amino acids
Theoretical weight: 38.84 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
A0A287AE88 (Residues: 36-406; Coverage: 84%)
Pfam: NAD dependent epimerase/dehydratase family
InterPro:
Chain: K
Length: 42 amino acids
Theoretical weight: 5.05 KDa
Source organism: Sus scrofa
UniProt:
Pfam: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
InterPro: NADH-ubiquinone oxidoreductase flavoprotein 3
Length: 42 amino acids
Theoretical weight: 5.05 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
I3LRR4 (Residues: 69-110; Coverage: 38%)
Pfam: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
InterPro: NADH-ubiquinone oxidoreductase flavoprotein 3
Chain: L
Length: 125 amino acids
Theoretical weight: 14.44 KDa
Source organism: Sus scrofa
UniProt:
Pfam: NADH dehydrogenase ubiquinone Fe-S protein 4
InterPro:
Length: 125 amino acids
Theoretical weight: 14.44 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
A0A4X1SN37 (Residues: 51-175; Coverage: 71%)
Pfam: NADH dehydrogenase ubiquinone Fe-S protein 4
InterPro:
Chain: M
Length: 690 amino acids
Theoretical weight: 75.77 KDa
Source organism: Sus scrofa
UniProt:
Pfam:
Length: 690 amino acids
Theoretical weight: 75.77 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
A0A4X1V1H9 (Residues: 29-718; Coverage: 95%)
Pfam:
- 2Fe-2S iron-sulfur cluster binding domain
- NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
- NADH-quinone oxidoreductase subunit 3, ferredoxin-like domain
- NADH-ubiquinone oxidoreductase NDSU1/NuoG-like, 4Fe-4S domain
- Molybdopterin oxidoreductase
- NADH-ubiquinone oxidoreductase subunit G, C-terminal
- 2Fe-2S ferredoxin-type iron-sulfur binding domain
- 2Fe-2S ferredoxin-like superfamily
- NADH:ubiquinone oxidoreductase, subunit G
- NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site
- NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding
- Molybdopterin oxidoreductase, 4Fe-4S domain
- Molybdopterin oxidoreductase
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial-like
Chain: N
Length: 144 amino acids
Theoretical weight: 17.03 KDa
Source organism: Sus scrofa
UniProt:
Pfam: NADH ubiquinone oxidoreductase subunit NDUFA12
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
Length: 144 amino acids
Theoretical weight: 17.03 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
F1SQP4 (Residues: 2-145; Coverage: 99%)
Pfam: NADH ubiquinone oxidoreductase subunit NDUFA12
InterPro: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
Chain: O
Length: 217 amino acids
Theoretical weight: 23.83 KDa
Source organism: Sus scrofa
UniProt:
Pfam: Thioredoxin-like [2Fe-2S] ferredoxin
InterPro:
Length: 217 amino acids
Theoretical weight: 23.83 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
A0A287BG40 (Residues: 33-249; Coverage: 87%)
Pfam: Thioredoxin-like [2Fe-2S] ferredoxin
InterPro:
Chain: P
Length: 208 amino acids
Theoretical weight: 24.52 KDa
Source organism: Sus scrofa
UniProt:
Pfam: Respiratory-chain NADH dehydrogenase, 30 Kd subunit
InterPro:
Length: 208 amino acids
Theoretical weight: 24.52 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
A0A286ZNN4 (Residues: 43-250; Coverage: 79%)
Pfam: Respiratory-chain NADH dehydrogenase, 30 Kd subunit
InterPro:
Chain: Q
Length: 385 amino acids
Theoretical weight: 44.04 KDa
Source organism: Sus scrofa
UniProt:
Pfam: Respiratory-chain NADH dehydrogenase, 49 Kd subunit
InterPro:
Length: 385 amino acids
Theoretical weight: 44.04 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
F1S1A8 (Residues: 85-469; Coverage: 86%)
Pfam: Respiratory-chain NADH dehydrogenase, 49 Kd subunit
InterPro:
Chain: T
Length: 96 amino acids
Theoretical weight: 10.57 KDa
Source organism: Sus scrofa
UniProt:
Pfam: Zinc-finger domain
InterPro:
Length: 96 amino acids
Theoretical weight: 10.57 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
F1S031 (Residues: 28-123; Coverage: 78%)
Pfam: Zinc-finger domain
InterPro:
Chain: W
Length: 29 amino acids
Theoretical weight: 3.2 KDa
Source organism: Sus scrofa
UniProt:
InterPro: GRIM-19
Length: 29 amino acids
Theoretical weight: 3.2 KDa
Source organism: Sus scrofa
UniProt:
- Canonical:
A0A8D1NRT6 (Residues: 3-31; Coverage: 20%)
InterPro: GRIM-19