Structure for peptidase A01.041: BACE2 g.p. (Homo sapiens)

PDB	Organism	Resolution	Comment
2EWY_A	Homo sapiens	3.10 Å	complex with hydroxyethylenamine transition-state inhibitor N-(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methylbenzyl)amino]propyldibenzo[B,F]oxepine-10-carboxamide
One molecule of the oligomer is shown. Active site residues are shown in ball-and-stick representation: Asp110 and Asp303 in pink, and Tyr149 in green. Bound inhibitor is shown in green in ball-and-stick representation.

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TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Homo sapiens
complex with hydroxyethylenamine transition-state inhibitor N-(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methylbenzyl)amino]propyldibenzo[B,F]oxepine-10-carboxamide	3.10 Å	2EWY	2EWY	2EWY	2EWY	2EWY	2EWY	Ostermann et al., 2006
mature peptidase	1.90 Å	3ZKG	3ZKG	3ZKG	3ZKG	3ZKG	3ZKG	Banner et al., 2013
mature peptidase	2.40 Å	3ZKI	3ZKI	3ZKI	3ZKI	3ZKI	3ZKI	Banner et al., 2013
mature peptidase	1.85 Å	3ZKM	3ZKM	3ZKM	3ZKM	3ZKM	3ZKM	Banner et al., 2013
mature peptidase	2.00 Å	3ZKN	3ZKN	3ZKN	3ZKN	3ZKN	3ZKN	Banner et al., 2013
mature peptidase	1.51 Å	3ZKQ	3ZKQ	3ZKQ	3ZKQ	3ZKQ	3ZKQ	Banner et al., 2013
mature peptidase	2.11 Å	3ZKS	3ZKS	3ZKS	3ZKS	3ZKS	3ZKS	Banner et al., 2013
mature peptidase	2.37 Å	3ZKX	3ZKX	3ZKX	3ZKX	3ZKX	3ZKX	Banner et al., 2013
mature peptidase	3.20 Å	3ZL7	3ZL7	3ZL7	3ZL7	3ZL7	3ZL7	Banner et al., 2013
mature peptidase	2.10 Å	3ZLQ	3ZLQ	3ZLQ	3ZLQ	3ZLQ	3ZLQ	Hilpert et al., 2013
mature peptidase	1.85 Å	4BEL	4BEL	4BEL	4BEL	4BEL	4BEL	Banner et al., 2013
mature peptidase	2.21 Å	4BFB	4BFB	4BFB	4BFB	4BFB	4BFB	Banner et al., 2013