Substrates for peptidase S45.001: penicillin G acylase precursor

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
cephalosporin acylase precursor P07662 30-720 peptide-Gly189+Asp-peptide P NT Leu Gly Glu Gly Asp Pro Pro Asp Lee & Park, 1998 17763
cephalosporin acylase precursor P07662 30-720 peptide-Gly198+Ser-peptide P NT Ala Asp Gln Gly Ser Asn Ser Trp Lee & Park, 1998
penicillin G acylase precursor ({Pseudomonas} sp. GK16) A4ZVL3 1-720 peptide-Gly198+Ser-peptide P Ala Asp Gln Gly Ser Asn Ser Trp Park, 2004