› › Function and Biology

Complex I from Ovis aries at pH9, Closed state

Source organism: Ovis aries
Biochemical function: NADH dehydrogenase (ubiquinone) activity
Biological process: mitochondrial electron transport, NADH to ubiquinone
Cellular component: obsolete mitochondrial respiratory chain complex I

Quick links

EC 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating)

Reaction catalysed:
NADH + ubiquinone + 5 H(+)(Side 1) = NAD(+) + ubiquinol + 4 H(+)(Side 2)
Systematic name:
NADH:ubiquinone oxidoreductase
Alternative Name(s):
  • Coenzyme Q reductase
  • Complex 1 dehydrogenase
  • Complex I (NADH:Q1 oxidoreductase)
  • Complex I (electron transport chain)
  • Complex I (mitochondrial electron transport)
  • DPNH-coenzyme Q reductase
  • DPNH-ubiquinone reductase
  • Dihydronicotinamide adenine dinucleotide-coenzyme Q reductase
  • Electron transfer complex I
  • Mitochondrial electron transport complex 1
  • Mitochondrial electron transport complex I
  • NADH coenzyme Q1 reductase
  • NADH dehydrogenase (ubiquinone)
  • NADH-CoQ oxidoreductase
  • NADH-CoQ reductase
  • NADH-Q6 oxidoreductase
  • NADH-coenzyme Q oxidoreductase
  • NADH-coenzyme Q reductase
  • NADH-ubiquinone oxidoreductase
  • NADH-ubiquinone reductase
  • NADH-ubiquinone-1 reductase
  • NADH:ubiquinone oxidoreductase complex
  • Reduced nicotinamide adenine dinucleotide-coenzyme Q reductase
  • Type 1 dehydrogenase
  • Ubiquinone reductase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF00361
Domain description: Proton-conducting membrane transporter
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
  2. NADH-ubiquinone oxidoreductase chain 4
  3. NADH-ubiquinone oxidoreductase chain 2
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF00361 (Proton-conducting membrane transporter) in NADH-ubiquinone oxidoreductase chain 5. Showing 1 copy in chain F [auth L].
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF00361 (Proton-conducting membrane transporter) in NADH-ubiquinone oxidoreductase chain 4. Showing 1 copy in chain G [auth M].
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF00361 (Proton-conducting membrane transporter) in NADH-ubiquinone oxidoreductase chain 2. Showing 1 copy in chain H [auth N].

PF05347
Domain description: Complex 1 protein (LYR family)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
  2. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF05347 (Complex 1 protein (LYR family)) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9. Showing 1 copy in chain W [auth t].

PF00550
Domain description: Phosphopantetheine attachment site
Occurring in:
  1. Acyl carrier protein
The deposited structure of PDB entry 7zeb contains 2 copies of Pfam domain PF00550 (Phosphopantetheine attachment site) in Acyl carrier protein. Showing 1 copy in chain K [auth X].

PF15879
Domain description: NADH-ubiquinone oxidoreductase MWFE subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF15879 (NADH-ubiquinone oxidoreductase MWFE subunit) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1. Showing 1 copy in chain CA [auth z].

PF08040
Domain description: MNLL subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF08040 (MNLL subunit) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1. Showing 1 copy in chain BA [auth y].

PF15088
Domain description: NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF15088 (NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial) in NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial. Showing 1 copy in chain AA [auth x].

PF10183
Domain description: ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF10183 (ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial. Showing 1 copy in chain Z [auth w].

PF05821
Domain description: NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF05821 (NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial. Showing 1 copy in chain Y [auth v].

PF14813
Domain description: NADH dehydrogenase 1 beta subcomplex subunit 2
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF14813 (NADH dehydrogenase 1 beta subcomplex subunit 2) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial. Showing 1 copy in chain X [auth u].

PF05676
Domain description: NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF05676 (NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7. Showing 1 copy in chain V [auth s].

PF09782
Domain description: NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF09782 (NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6. Showing 1 copy in chain U [auth r].

PF06212
Domain description: GRIM-19 protein
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF06212 (GRIM-19 protein) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13. Showing 1 copy in chain T [auth q].

PF07225
Domain description: NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF07225 (NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4. Showing 1 copy in chain S [auth p].

PF06374
Domain description: NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 subunit C2
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF06374 (NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2)) in NADH dehydrogenase [ubiquinone] 1 subunit C2. Showing 1 copy in chain R [auth o].

PF08122
Domain description: NADH-ubiquinone oxidoreductase B12 subunit family
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF08122 (NADH-ubiquinone oxidoreductase B12 subunit family) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3. Showing 1 copy in chain Q [auth n].

PF14987
Domain description: NADH dehydrogenase 1 alpha subcomplex subunit 3
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF14987 (NADH dehydrogenase 1 alpha subcomplex subunit 3) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3. Showing 1 copy in chain P [auth m].

PF10200
Domain description: NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
Occurring in:
  1. Complex I-15 kDa
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF10200 (NADH:ubiquinone oxidoreductase, NDUFS5-15kDa) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 5. Showing 1 copy in chain O [auth l].

PF01712
Domain description: Deoxynucleoside kinase
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF01712 (Deoxynucleoside kinase) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial. Showing 1 copy in chain N [auth k].

PF05071
Domain description: NADH ubiquinone oxidoreductase subunit NDUFA12
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF05071 (NADH ubiquinone oxidoreductase subunit NDUFA12) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12. Showing 1 copy in chain RA [auth i].

PF07347
Domain description: NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF07347 (NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7. Showing 1 copy in chain QA [auth h].

PF04716
Domain description: ETC complex I subunit conserved region
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF04716 (ETC complex I subunit conserved region) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5. Showing 1 copy in chain OA [auth f].

PF05047
Domain description: Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF05047 (Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2. Showing 1 copy in chain NA [auth e].

PF01370
Domain description: NAD dependent epimerase/dehydratase family
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF01370 (NAD dependent epimerase/dehydratase family) in NAD-dependent epimerase/dehydratase domain-containing protein. Showing 1 copy in chain MA [auth d].

PF04800
Domain description: NADH dehydrogenase ubiquinone Fe-S protein 4
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF04800 (NADH dehydrogenase ubiquinone Fe-S protein 4) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. Showing 1 copy in chain LA [auth c].

PF10276
Domain description: Zinc-finger domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF10276 (Zinc-finger domain) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial. Showing 1 copy in chain KA [auth b].

PF15880
Domain description: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF15880 (NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial) in NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial. Showing 1 copy in chain JA [auth a].

PF10249
Domain description: NADH-ubiquinone oxidoreductase subunit 10
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF10249 (NADH-ubiquinone oxidoreductase subunit 10) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10. Showing 1 copy in chain M [auth Z].

PF06747
Domain description: CHCH domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF06747 (CHCH domain) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8. Showing 1 copy in chain L [auth Y].

PF09781
Domain description: NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF09781 (NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit) in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial. Showing 1 copy in chain J [auth W].

PF02466
Domain description: Tim17/Tim22/Tim23/Pmp24 family
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF02466 (Tim17/Tim22/Tim23/Pmp24 family) in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11. Showing 1 copy in chain I [auth V].

PF06444
Domain description: NADH dehydrogenase subunit 2 C-terminus
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 2
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF06444 (NADH dehydrogenase subunit 2 C-terminus) in NADH-ubiquinone oxidoreductase chain 2. Showing 1 copy in chain H [auth N].

PF01059
Domain description: NADH-ubiquinone oxidoreductase chain 4, amino terminus
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF01059 (NADH-ubiquinone oxidoreductase chain 4, amino terminus) in NADH-ubiquinone oxidoreductase chain 4. Showing 1 copy in chain G [auth M].

PF06455
Domain description: NADH dehydrogenase subunit 5 C-terminus
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF06455 (NADH dehydrogenase subunit 5 C-terminus) in NADH-ubiquinone oxidoreductase chain 5. Showing 1 copy in chain F [auth L].

PF00662
Domain description: NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF00662 (NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus) in NADH-ubiquinone oxidoreductase chain 5. Showing 1 copy in chain F [auth L].

PF00420
Domain description: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4L
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF00420 (NADH-ubiquinone/plastoquinone oxidoreductase chain 4L) in NADH-ubiquinone oxidoreductase chain 4L. Showing 1 copy in chain E [auth K].

PF00499
Domain description: NADH-ubiquinone/plastoquinone oxidoreductase chain 6
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 6
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF00499 (NADH-ubiquinone/plastoquinone oxidoreductase chain 6) in NADH-ubiquinone oxidoreductase chain 6. Showing 1 copy in chain D [auth J].

PF00146
Domain description: NADH dehydrogenase
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 1
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF00146 (NADH dehydrogenase) in NADH-ubiquinone oxidoreductase chain 1. Showing 1 copy in chain C [auth H].

PF00507
Domain description: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 3
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF00507 (NADH-ubiquinone/plastoquinone oxidoreductase, chain 3) in NADH-ubiquinone oxidoreductase chain 3. Showing 1 copy in chain B [auth A].

PF12838
Domain description: 4Fe-4S dicluster domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF12838 (4Fe-4S dicluster domain) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial. Showing 1 copy in chain IA [auth 9].

PF01058
Domain description: NADH ubiquinone oxidoreductase, 20 Kd subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF01058 (NADH ubiquinone oxidoreductase, 20 Kd subunit) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial. Showing 1 copy in chain HA [auth 6].

PF00329
Domain description: Respiratory-chain NADH dehydrogenase, 30 Kd subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF00329 (Respiratory-chain NADH dehydrogenase, 30 Kd subunit) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial. Showing 1 copy in chain GA [auth 5].

PF00346
Domain description: Respiratory-chain NADH dehydrogenase, 49 Kd subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF00346 (Respiratory-chain NADH dehydrogenase, 49 Kd subunit) in NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial. Showing 1 copy in chain A [auth 4].

PF01257
Domain description: Thioredoxin-like [2Fe-2S] ferredoxin
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF01257 (Thioredoxin-like [2Fe-2S] ferredoxin) in NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial. Showing 1 copy in chain EA [auth 2].

PF10589
Domain description: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF10589 (NADH-ubiquinone oxidoreductase-F iron-sulfur binding region) in NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial. Showing 1 copy in chain DA [auth 1].

PF22461
Domain description: SLBB domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

PF01512
Domain description: Respiratory-chain NADH dehydrogenase 51 Kd subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
The deposited structure of PDB entry 7zeb contains 1 copy of Pfam domain PF01512 (Respiratory-chain NADH dehydrogenase 51 Kd subunit) in NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial. Showing 1 copy in chain DA [auth 1].

InterPro InterPro annotations
IPR003231
Domain description: Acyl carrier protein
Occurring in:
  1. Acyl carrier protein
IPR003918
Domain description: NADH:ubiquinone oxidoreductase
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4
IPR003917
Domain description: NADH:ubiquinone oxidoreductase, chain 2
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 2
IPR009081
Domain description: Phosphopantetheine binding ACP domain
Occurring in:
  1. Acyl carrier protein
IPR036736
Domain description: ACP-like superfamily
Occurring in:
  1. Acyl carrier protein
IPR001750
Domain description: NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
  2. NADH-ubiquinone oxidoreductase chain 4
  3. NADH-ubiquinone oxidoreductase chain 2
IPR001694
Domain description: NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 1
IPR017896
Domain description: 4Fe-4S ferredoxin-type, iron-sulphur binding domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
IPR010226
Domain description: NADH-quinone oxidoreductase, chain I
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
IPR006138
Domain description: NADH-ubiquinone oxidoreductase, 20 Kd subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
IPR022885
Domain description: NAD(P)H-quinone oxidoreductase subunit D/H
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
IPR019574
Domain description: NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
IPR000283
Domain description: NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
IPR002023
Domain description: NADH-quinone oxidoreductase subunit E-like
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
IPR017384
Domain description: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex subunit 1
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
IPR019329
Domain description: NADH:ubiquinone oxidoreductase, ESSS subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial
IPR008698
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7, NDUB7
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
IPR009346
Domain description: GRIM-19
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13
IPR009866
Domain description: NADH:ubiquinone oxidoreductase, subunit NDUFB4
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4
IPR009423
Domain description: NADH dehydrogenase [ubiquinone] 1 subunit C2, NDUC2
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 subunit C2
IPR012576
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
IPR026626
Domain description: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3
IPR019342
Domain description: NADH:ubiquinone oxidoreductase, iron-sulphur subunit 5
Occurring in:
  1. Complex I-15 kDa
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
IPR015828
Domain description: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
IPR007763
Domain description: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
IPR009947
Domain description: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
IPR008011
Domain description: Complex 1 LYR protein domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
  2. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
IPR016488
Domain description: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
IPR006806
Domain description: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
IPR007741
Domain description: Ribosomal protein/NADH dehydrogenase domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
IPR016464
Domain description: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
IPR006885
Domain description: NADH dehydrogenase ubiquinone Fe-S protein 4 mitochondrial-like
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
IPR026193
Domain description: NADH-ubiquinone oxidoreductase flavoprotein 3
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial
IPR016680
Domain description: NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
IPR006162
Domain description: Phosphopantetheine attachment site
Occurring in:
  1. Acyl carrier protein
IPR018086
Domain description: NADH:ubiquinone oxidoreductase, subunit 1, conserved site
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 1
IPR000440
Domain description: NADH:ubiquinone/plastoquinone oxidoreductase, chain 3
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 3
IPR017900
Domain description: 4Fe-4S ferredoxin, iron-sulphur binding, conserved site
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial
IPR010218
Domain description: NADH dehydrogenase, subunit C
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
IPR037232
Domain description: NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
IPR029014
Domain description: [NiFe]-hydrogenase, large subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
IPR001041
Domain description: 2Fe-2S ferredoxin-type iron-sulfur binding domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
IPR036249
Domain description: Thioredoxin-like superfamily
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
  2. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
IPR019575
Domain description: NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
IPR037207
Domain description: NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
IPR001949
Domain description: NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
IPR037225
Domain description: NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
IPR012575
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1, NDUB1
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1
IPR026192
Domain description: NADH-ubiquinone oxidoreductase 1 subunit C1
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
IPR016551
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, metazoa
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
IPR008699
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
IPR026627
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, animal type
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial
IPR045292
Domain description: NDUFB9, LYR domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
IPR033034
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
IPR019174
Domain description: NADH dehydrogenase 1, beta subcomplex, subunit 6
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6
IPR031314
Domain description: Deoxynucleoside kinase domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
IPR045299
Domain description: NDUFA6, LYR domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
IPR001509
Domain description: NAD-dependent epimerase/dehydratase
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
IPR036291
Domain description: NAD(P)-binding domain superfamily
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial
IPR038532
Domain description: NADH dehydrogenase ubiquinone Fe-S protein 4-like superfamily
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
IPR019401
Domain description: Zinc finger, CHCC-type
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
IPR016668
Domain description: NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial
IPR019377
Domain description: NADH-ubiquinone oxidoreductase, subunit 10
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
IPR039993
Domain description: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10
IPR010625
Domain description: CHCH
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
IPR019173
Domain description: NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
IPR039205
Domain description: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
Occurring in:
  1. NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11
IPR010933
Domain description: NADH dehydrogenase subunit 2, C-terminal
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 2
IPR010227
Domain description: NADH-quinone oxidoreductase, chain M/4
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4
IPR000260
Domain description: NADH:ubiquinone oxidoreductase chain 4, N-terminal
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4
IPR010934
Domain description: NADH dehydrogenase subunit 5, C-terminal
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
IPR001516
Domain description: NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
IPR003945
Domain description: NADH-quinone oxidoreductase, chain 5-like
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
IPR018393
Domain description: NADH-plastoquinone oxidoreductase, chain 5 subgroup
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 5
IPR039428
Domain description: NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4L
IPR001133
Domain description: NADH-ubiquinone oxidoreductase chain 4L/K
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 4L
IPR001457
Domain description: NADH:ubiquinone/plastoquinone oxidoreductase, chain 6
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 6
IPR042106
Domain description: NADH-ubiquinone/plastoquinone oxidoreductase chain 6, subunit NuoJ
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 6
IPR038430
Domain description: NADH:ubiquinone oxidoreductase, subunit 3 superfamily
Occurring in:
  1. NADH-ubiquinone oxidoreductase chain 3
IPR006137
Domain description: NADH:ubiquinone oxidoreductase-like, 20kDa subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial
IPR020396
Domain description: NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
IPR001268
Domain description: NADH:ubiquinone oxidoreductase, 30kDa subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
IPR001135
Domain description: NADH-quinone oxidoreductase, subunit D
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
IPR014029
Domain description: NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site
Occurring in:
  1. NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
IPR015405
Domain description: NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial-like
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
IPR006656
Domain description: Molybdopterin oxidoreductase
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
IPR006963
Domain description: Molybdopterin oxidoreductase, 4Fe-4S domain
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
IPR010228
Domain description: NADH:ubiquinone oxidoreductase, subunit G
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
IPR036010
Domain description: 2Fe-2S ferredoxin-like superfamily
Occurring in:
  1. NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
IPR042128
Domain description: NuoE domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
IPR041921
Domain description: NADH-quinone oxidoreductase subunit E, N-terminal
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
IPR019554
Domain description: Soluble ligand binding domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
IPR011538
Domain description: NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
IPR011537
Domain description: NADH ubiquinone oxidoreductase, F subunit
Occurring in:
  1. NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

Quick links